Germline transformation with Drosophila mutant actin genes induces constitutive expression of heat shock genes.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Cell

• Publication date

  1986-01-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0092-8674(86)90763-4PMID 3080247
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isolation of Drosophila flightless mutants which affect myofibrillar proteins of indirect flight muscle

  2004cited by this paper
• Cytogenic mapping and isolation of mutations of the β-Gal-1 locus of Drosophila melanogaster

  2004cited by this paper
• The flightless Drosophila mutant raised has two distinct genetic lesions affecting accumulation of myofibrillar proteins in flight muscles.

  1985cited by this paper
• Control elements of the Drosophila segmentation gene fushi tarazu.

  1985cited by this paper
• Actin gene mutations in Drosophila; heat shock activation in the indirect flight muscles

  1985cited by this paper
• Remote regulatory sequences of the Drosophila glue gene sgs3 as revealed by P-element transformation.

  1985cited by this paper
• The use of promoter fusions in Drosophila genetics: isolation of mutations affecting the heat shock response.

  1984cited by this paper
• Is actin a transcription initiation factor for RNA polymerase B?

  1984cited by this paper
• Organization of contractile protein genes within the 88F subdivision of the D. melanogaster third chromosome.

  1984cited by this paper
• Analysis of P transposable element functions in Drosophila.

  1984cited by this paper
• Drosophila melanogaster has only one myosin alkali light-chain gene which encodes a protein with considerable amino acid sequence homology to chicken myosin alkali light chains

  1984cited by this paper
• Microinjection of actin-binding proteins and actin antibodies demonstrates involvement of nuclear actin in transcription of lampbrush chromosomes.

  1984cited by this paper
• A nonsense mutation within the act88F actin gene disrupts myofibril formation in Drosophila indirect flight muscles.

  1984cited by this paper
• Transcripts of the six Drosophila actin genes accumulate in a stage- and tissue-specific manner.

  1983cited by this paper
• Cellular oncogenes and retroviruses.

  1983cited by this paper
• Vectors for P element-mediated gene transfer in Drosophila.

  1983cited by this paper
• New versatile plasmid vectors for expression of hybrid proteins coded by a cloned gene fused to lacZ gene sequences encoding an enzymatically active carboxy-terminal portion of beta-galactosidase.

  1983cited by this paper
• Two Drosophila actin genes in detail. Gene structure, protein structure and transcription during development.

  1983cited by this paper
• Identification of Drosophila indirect flight muscle myofibrillar proteins by means of two-dimensional electrophoresis.

  1982cited by this paper
• Transposition of cloned P elements into Drosophila germ line chromosomes.

  1982cited by this paper
• Genetic transformation of Drosophila with transposable element vectors.

  1982cited by this paper
• Translational control of protein synthesis in response to heat shock in D. melanogaster cells.

  1980cited by this paper
• The effect of heat shock on gene expression in Drosophila melanogaster.

  1978cited by this paper
• Isolation and characterization of flightless mutants in Drosophila melanogaster.

  1978cited by this paper
• The presence of actin in nuclei: a critical appraisal.

  1977cited by this paper
• Diffusible and bound actin nuclei of Xenopus laevis oocytes.

  1977cited by this paper
• High resolution two-dimensional electrophoresis of proteins.

  1975cited by this paper
• Genetic variations of Drosophila melanogaster

  1967cited by this paper

• Classic and exertional heatstroke

  2022cites this paper
• Actin.

  2020cites this paper
• Transcriptome analysis of IFM-specific actin and myosin nulls in Drosophila melanogaster unravels lesion-specific expression blueprints across muscle mutations.

  2017cites this paper
• A note in passing : Walter Gehring and desert ants

  2014cites this paper
• Differential scales of protein quality control.

  2014influential citation
• A note in passing: Walter Gehring and desert ants

  2014cites this paper
• The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis

  2011cites this paper
• Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies.

  2011cites this paper
• Protein homeostasis in models of aging and age-related conformational disease.

  2010cites this paper
• Dominant Negative Mutant Actins Identified in Flightless Drosophila Can Be Classified into Three Classes*

  2009cites this paper
• Molecular Basis of Muscle Structure

  2006cites this paper
• Actin and Arthrin

  2006cites this paper
• Overexpression of troponin T in Drosophila muscles causes a decrease in the levels of thin-filament proteins.

  2005cites this paper
• 2.2 – The Development of the Flight and Leg Muscle

  2005cites this paper
• Flight muscle properties and aerodynamic performance of Drosophila expressing a flightin transgene

  2005influential citation
• Invertebrate muscles: muscle specific genes and proteins.

  2005cites this paper
• Mutant actin: A dead end?

  2005cites this paper
• Expression and function of the Drosophila ACT88F actin isoform is not restricted to the indirect flight muscles

  2004cites this paper
• Derepression of the activity of genetically engineered heat shock factor causes constitutive synthesis of heat shock proteins and increased thermotolerance in transgenic <i>Arabidopsis</i>

  2001cites this paper
• The role of Ultrabithorax in the patterning of adult thoracic muscles in Drosophila melanogaster

  2001cites this paper
• Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans.

  2000cites this paper
• Apterous mediates development of direct flight muscles autonomously and indirect flight muscles through epidermal cues.

  2000cites this paper
• A direct screen identifies new flight muscle mutants on the Drosophila second chromosome.

  1999cites this paper
• Substitution of flight muscle-specific actin by human (beta)-cytoplasmic actin in the indirect flight muscle of Drosophila.

  1999cites this paper
• Differential epitope tagging of actin in transformed Drosophila produces distinct effects on myofibril assembly and function of the indirect flight muscle.

  1999influential citation
• Direct observation of stress response in Caenorhabditis elegans using a reporter transgene.

  1999cites this paper
• A comparison of Hsp70 expression and thermotolerance in adults and larvae of three Drosophila species.

  1999cites this paper
• Physical activity, muscle, and the HSP70 response.

  1998cites this paper
• HSF3, a new heat shock factor from Arabidopsis thaliana, derepresses the heat shock response and confers thermotolerance when overexpressed in transgenic plants

  1998cites this paper
• Amino Acid Analogs Activate NF-κB through Redox-dependent IκB-α Degradation by the Proteasome without Apparent IκB-α Phosphorylation

  1998cites this paper
• Patterning Muscles Using Organizers: Larval Muscle Templates and Adult Myoblasts Actively Interact to Pattern the Dorsal Longitudinal Flight Muscles of Drosophila

  1998cites this paper
• Biochemical events in the activation and attenuation of the heat shock transcriptional response

  1998cites this paper
• Amino acid analogs activate NF-kappaB through redox-dependent IkappaB-alpha degradation by the proteasome without apparent IkappaB-alpha phosphorylation. Consequence on HIV-1 long terminal repeat activation.

  1998cites this paper
• Hsp70 and larval thermotolerance in Drosophila melanogaster: how much is enough and when is more too much?

  1998cites this paper
• Functional Nonequivalence of Drosophila Actin Isoforms

  1998cites this paper
• Homeotic genes and the regulation of myoblast migration, fusion, and fibre-specific gene expression during adult myogenesis in Drosophila.

  1997cites this paper
• Isolation of 88F actin mutants of Drosophila melanogaster and possible alterations in the mutant actin structures.

  1996cites this paper
• Patterning the dorsal longitudinal flight muscles (DLM) of Drosophila: insights from the ablation of larval scaffolds.

  1996cites this paper
• Stress proteins elicited by cold shock in the biting midge, Culicoides variipennis sonorensis wirth and jones

  1996cites this paper
• Muscle organizers in Drosophila: the role of persistent larval fibers in adult flight muscle development.

  1996cites this paper
• Muscle actin gene from Aedes aegypti (Diptera:Culicidae).

  1996cites this paper
• Transplanted wing and leg imaginal discs in Drosophila melanogaster demonstrate interactions between epidermis and myoblasts in muscle formation

  1996cites this paper
• Derepression of the activity of genetically engineered heat shock factor causes constitutive synthesis of heat shock proteins and increased thermotolerance in transgenic Arabidopsis.

  1995cites this paper
• Heat shock transcription factors: structure and regulation.

  1995cites this paper
• Monitoring development and pathology of Drosophila indirect flight muscles using green fluorescent protein.

  1995cites this paper
• Heat shock protein synthesis and thermotolerance in Cataglyphis, an ant from the Sahara desert.

  1995cites this paper
• Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene.

  1995cites this paper
• Recovery of dominant, autosomal flightless mutants of Drosophila melanogaster and identification of a new gene required for normal muscle structure and function.

  1994cites this paper
• Transformation of Drosophila melanogaster with the wild-type myosin heavy-chain gene: rescue of mutant phenotypes and analysis of defects caused by overexpression

  1994cites this paper
• Transgenic hsp 16‐Lacz strains of the soil nematode caenorhabditis elegans as biological monitors of environmental stress

  1994cites this paper
• Characterization of denatured protein inducers of the heat shock (stress) response in Xenopus laevis oocytes.

  1994cites this paper
• Basic methods for Drosophila muscle biology.

  1994cites this paper
• Developmental regulation of the Drosophila tropomyosin II gene in different muscles is controlled by muscle-type-specific intron enhancer elements and distal and proximal promoter control elements.

  1993cites this paper
• Drosophila hairy pair-rule gene regulates embryonic patterning outside its apparent stripe domains.

  1993cites this paper
• Coordinate regulation of Drosophila tropomyosin gene expression is controlled by multiple muscle-type-specific positive and negative enhancer elements.

  1993cites this paper
• Analysis of multistage mouse skin carcinogenesis by retroviral mediated gene transfer

  1993cites this paper
• A non-flight muscle isoform of Drosophila tropomyosin rescues an indirect flight muscle tropomyosin mutant

  1993cites this paper
• Role of the major heat shock proteins as molecular chaperones.

  1993cites this paper
• Muscle actin genes in insects.

  1993cites this paper
• A new method for manipulating transgenes: engineering heat tolerance in a complex, multicellular organism.

  1993cites this paper
• Molecular genetics of actin function.

  1993cites this paper
• Molecular genetic analysis of muscle development, structure, and function in Drosophila.

  1993cites this paper
• Characterization of Drosophila melanogaster Act88F Actin Allele with Point Mutation in Myosin Binding Site

  1993cites this paper
• Sequence analysis of the indirect flight muscle actin-encoding gene of Drosophila simulans.

  1992cites this paper
• Heat shock response in Drosophila.

  1992cites this paper
• Heat shock response inDrosophila

  1992cites this paper
• Development of the indirect flight muscles of Drosophila.

  1991influential citation
• Heat shock gene activation by mutant actin is independent of myofibril degeneration in Drosophila muscle.

  1991cites this paper
• Protein engineering and the study of muscle contraction in Drosophila flight muscles

  1991cites this paper
• Changes in hsp70 alter thermotolerance and heat-shock regulation in Drosophila.

  1991cites this paper
• Characterisation of missense mutations in the Act88F gene of Drosophila melanogaster

  1991cites this paper
• Functional and ultrastructural effects of a missense mutation in the indirect flight muscle-specific actin gene of Drosophila melanogaster.

  1991cites this paper
• Developmental and tissue specific control of the heat shock induced 70 kDa related proteins in the flesh fly, Sarcophaga crassipalpis

  1990cites this paper
• Actin with tumor-related mutation is antimorphic in Drosophila muscle: two distinct modes of myofibrillar disruption by antimorphic actins.

  1990cites this paper
• Cold shock elicits expression of heat shock proteins in the flesh fly, Sarcophaga crassipalpis

  1990cites this paper
• CHAPTER 6 – Biochemistry of Heat Shock Responses in Plants

  1990cites this paper
• Gene Transfer in Insects

  1989cites this paper
• Protein synthesis during flight muscle development in normal and wupB indirect flight muscles of Drosophila melanogaster

  1989cites this paper
• Genetic dissection of Drosophila myofibril formation: effects of actin and myosin heavy chain null alleles.

  1989cites this paper
• Modulation of protein degradation in mammalian cells by ligands and stress.

  1989cites this paper
• Bioenergetics, Behavior, and Resource Partitioning in Stressed Habitats: Biophysical and Molecular Approaches

  1989cites this paper
• Effects of heat and other inducers of the stress response on protein degradation in Chinese hamster and Drosophila cells

  1989cites this paper
• Tissue-specific expression of the 79B actin gene during Drosophila development.

  1989cites this paper
• UbiA, the major polyubiquitin locus in Caenorhabditis elegans, has unusual structural features and is constitutively expressed

  1989cites this paper
• Formation of reverse rigor chevrons by myosin heads

  1989cites this paper
• Alternative 5C actin transcripts are localized in different patterns during Drosophila embryogenesis.

  1989cites this paper
• Molecular and genetic characterization of the Drosophila melanogaster 87E actin gene region.

  1988cites this paper
• Protein Breakdown and the Heat-Shock Response

  1988cites this paper
• Identification of calcium binding proteins in two-dimensional gel electrophoretic pattern of Drosophila thorax and their distribution in two types of muscles.

  1988cites this paper
• Purified human factor activates heat shock promoter in a HeLa cell-free transcription system.

  1988cites this paper
• Transformation and rescue of a flightless Drosophila tropomyosin mutant.

  1987cites this paper
• Arthrin, a myofibrillar protein of insect flight muscle, is an actin-ubiquitin conjugate.

  1987cites this paper
• Expression of heat shock genes in homologous and heterologous systems

  1987cites this paper
• Retroviruses and the study of cell lineage.

  1987cites this paper
• Heat shock proteins from the lungless salamanders Eurycea bislineata and Desmognathus ochrophaeus

  1987cites this paper
• The white gene as a marker in a new P-element vector for gene transfer in Drosophila.

  1987cites this paper
• Expression of transfected mutant beta-actin genes: alterations of cell morphology and evidence for autoregulation in actin pools

  1987cites this paper
• Mutations that induce the heat shock response of Drosophila.

  1987cites this paper
• Two missense alleles of the Drosophila melanogaster act88F actin gene are strongly antimorphic but only weakly induce synthesis of heat shock proteins

  1987influential citation
• 5'-flanking sequence required for regulated expression of a muscle-specific Drosophila melanogaster actin gene

  1986cites this paper