RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression

RBM4 modulates alternative exon selection of Numb and up-regulates proneural Mash1 gene expression, possibly via specific Numb isoforms. RBM4 overexpression promotes neuronal cell differentiation. Moreover, RBM4 is essential for neurite outgrowth in primary cortical neurons by modulating specific Numb isoform expression.

• Publication year

  2016

• Venue

  Molecular Biology of the Cell

• Publication date

  2016-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E15-11-0798PMID 27009199PMCID 4865323
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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