Effects of Proton Linkage on Thermodynamic Properties of Enzyme- Antibiotic Complexes of the Aminoglycoside Nucleotidyltransferase (2")-Ia

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Thermodynamics and Catalysis

• Publication date

  2011-06-30

• Fields of study

  Chemistry

• Identifiers
  DOI 10.4172/2157-7544.1000105
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Aminoglycoside modifying enzymes.

  2010cited by this paper
• Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme.

  2010cited by this paper
• The Crystal Structures of Substrate and Nucleotide Complexes of Enterococcus faecium Aminoglycoside-2′′-Phosphotransferase-IIa [APH(2′′)-IIa] Provide Insights into Substrate Selectivity in the APH(2′′) Subfamily

  2009cited by this paper
• Pseudomonas aeruginosa - a phenomenon of bacterial resistance.

  2009cited by this paper
• Protein‐Carbohydrate Interaction: Fundamental Considerations

  2008cited by this paper
• Dissection of aminoglycoside-enzyme interactions: a calorimetric and NMR study of neomycin B binding to the aminoglycoside phosphotransferase(3')-IIIa.

  2006cited by this paper
• Molecular determinants of affinity for aminoglycoside binding to the aminoglycoside nucleotidyltransferase(2'')-Ia.

  2006cited by this paper
• Aminoglycoside Resistance in Pseudomonas aeruginosa

  2005cited by this paper
• Enzyme-substrate interactions with an antibiotic resistance enzyme: aminoglycoside nucleotidyltransferase(2'')-Ia characterized by kinetic and thermodynamic methods.

  2005cited by this paper
• Thermodynamics of aminoglycoside binding to aminoglycoside-3'-phosphotransferase IIIa studied by isothermal titration calorimetry.

  2004cited by this paper
• A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones.

  2004cited by this paper
• Isolation of aminoglycoside nucleotidyltransferase (2'')-Ia from inclusion bodies as active, monomeric enzyme.

  2004cited by this paper
• The determinants of carboxyl pKa values in turkey ovomucoid third domain

  2004cited by this paper
• Thermodynamic Quantities for the Ionization Reactions of Buffers

  2002cited by this paper
• Structural Basis of Perturbed pKa Values of Catalytic Groups in Enzyme Active Sites

  2002cited by this paper
• Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry.

  2002cited by this paper
• Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry

  2002cited by this paper
• Classical electrostatics in biology and chemistry.

  1995cited by this paper
• Calorimetric analysis of the binding of lectins with overlapping carbohydrate-binding ligand specificities.

  1995cited by this paper
• Structural investigation of the antibiotic and ATP-binding sites in kanamycin nucleotidyltransferase.

  1995cited by this paper
• Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

  1993cited by this paper
• Rapid measurement of binding constants and heats of binding using a new titration calorimeter.

  1989cited by this paper
• Substrate specificities and structure-activity relationships for the nucleotidylation of antibiotics catalyzed by aminoglycoside nucleotidyltransferase 2''-I.

  1988cited by this paper
• Correlation of aminoglycoside resistance with the KmS and Vmax/Km ratios of enzymatic modification of aminoglycosides by 2''-O-nucleotidyltransferase

  1985cited by this paper
• Intercontinental spread of a new antibiotic resistance gene on an epidemic plasmid.

  1985cited by this paper
• Comparison of aminoglycoside resistance patterns in Japan, Formosa, and Korea, Chile, and the United States

  1985cited by this paper
• Purification and properties of gentamicin nucleotidyltransferase from Escherichia coli: nucleotide specificity, pH optimum, and the separation of two electrophoretic variants.

  1984cited by this paper
• Relation between aminoglycoside 2"-O-nucleotidyltransferase activity and aminoglycoside resistance

  1984cited by this paper
• Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.

  1974cited by this paper
• Calorimetric determination of the heat of oxygenation of human hemolgobin as a function of pH and the extent of reaction.

  1974cited by this paper
• Mechanisms of antibiotic resistance in bacteria.

  1973cited by this paper
• Calorimetric titration of lysozyme.

  1972cited by this paper
• Thermal titrimetric evaluation of the heats of ionization of the commonly occurring amino acids and their derivatives.

  1971cited by this paper

• Radiation synthesis of pH-sensitive 2-(dimethylamino)ethyl methacrylate/ polyethylene oxide/ZnS nanocomposite hydrogel membrane for wound dressing application

  2022cites this paper
• History of Chemistry: Review

  2016cites this paper
• Examining the Functional Consequences of the Flexibility of Aminoglycoside Phosphotransferase (3’)-IIIa

  2014cites this paper
• Thermodynamics of transport through the ammonium transporter Amt-1 investigated with free energy calculations.

  2012cites this paper
• Effect of protein dynamics and solvent in ligand recognition by promiscuous aminoglycoside-modifying enzymes.

  2012cites this paper