Peptide ligands for the melanin-concentrating hormone (MCH) receptor 1.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Current Topics in Medicinal Chemistry

• Publication date

  2007-07-31

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.2174/156802607782194734PMID 17897029
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure-activity relationships of melanin-concentrating hormone.

  2009cited by this paper
• Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists.

  2006cited by this paper
• The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance

  2005cited by this paper
• Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice.

  2005cited by this paper
• Therapeutic potential of melanin-concentrating hormone-1 receptor antagonists for the treatment of obesity

  2004cited by this paper
• Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats.

  2003cited by this paper
• Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways.

  2003cited by this paper
• Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.

  2002cited by this paper
• Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression.

  2002cited by this paper
• Synthesis and Biological Evaluation in Vitro of a Selective, High Potency Peptide Agonist of Human Melanin-concentrating Hormone Action at Human Melanin-concentrating Hormone Receptor 1*

  2002cited by this paper
• Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist

  2002cited by this paper
• T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist.

  2002cited by this paper
• SLC-1 receptor mediates effect of melanin-concentrating hormone on feeding behavior in rat: a structure-activity study.

  2001cited by this paper
• Structure-Activity Relationship Studies of Melanin-concentrating Hormone (MCH)-related Peptide Ligands at SLC-1, the Human MCH Receptor*

  2001cited by this paper
• Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

  2001cited by this paper
• Short segment of human melanin-concentrating hormone that is sufficient for full activation of human melanin-concentrating hormone receptors 1 and 2.

  2001cited by this paper
• Molecular Cloning and Functional Characterization of MCH2, a Novel Human MCH Receptor*

  2001cited by this paper
• [125I]‐S36057: a new and highly potent radioligand for the melanin‐concentrating hormone receptor

  2001cited by this paper
• Melanin-concentrating hormone receptor: an orphan receptor fits the key.

  2000cited by this paper
• The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways.

  2000cited by this paper
• Synthesis and characterization of new radioligands for the mammalian melanin-concentrating hormone (MCH) receptor.

  1999cited by this paper
• Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1

  1999cited by this paper
• Mice lacking melanin-concentrating hormone are hypophagic and lean

  1998cited by this paper
• Melanin-concentrating hormone is a potent anorectic peptide regulated by food-deprivation and glucopenia in the rat.

  1996cited by this paper
• A role for melanin-concentrating hormone in the central regulation of feeding behaviour

  1996cited by this paper
• Binding sites for melanin-concentrating hormone (MCH) in brain synaptosomes and membranes from peripheral tissues identified with highly tritiated MCH.

  1995cited by this paper
• The melanin‐concentrating hormone system of the rat brain: An immuno‐ and hybridization histochemical characterization

  1992cited by this paper
• Structure-activity studies with fragments and analogous of salmonid melanin-concentrating hormone.

  1990cited by this paper
• Structure of the human melanin concentrating hormone mRNA.

  1990cited by this paper
• Characterization of melanin-concentrating hormone from rat hypothalamus.

  1989cited by this paper
• Melanin concentrating hormone. III. Melanin concentrating hormone (MCH): the message sequence.

  1989cited by this paper
• Melanin concentrating hormone (MCH): synthesis and bioactivity studies of MCH fragment analogues.

  1989cited by this paper
• Melanin concentrating hormone analogues: contraction of the cyclic structure. 1. Agonist activity.

  1988cited by this paper
• Characterization of melanin-concentrating hormone in chum salmon pituitaries

  1983cited by this paper
• The teleost melanin-concentrating hormone -- a pituitary hormone of hypothalamic origin.

  1979cited by this paper

• Angiostrongylus cantonensis induces energy imbalance and dyskinesia in mice by reducing the expression of melanin-concentrating hormone

  2024cites this paper
• The Role of Melanin-Concentrating Hormone and Its Receptors in Energy Homeostasis

  2013cites this paper
• Fighting Obesity with a Sugar-Based Library: Discovery of Novel MCH-1R Antagonists by a New Computational-VAST Approach for Exploration of GPCR Binding Sites

  2013cites this paper
• Peripheral injections of melanin-concentrating hormone receptor 1 antagonist S38151 decrease food intake and body weight in rodent obesity models

  2012cites this paper
• Recent progress in the discovery of melanin-concentrating hormone 1-receptor antagonists

  2011cites this paper
• MCH receptor peptide agonists and antagonists.

  2009cites this paper
• Promising strategies for obesity pharmacotherapy: melanocortin-4 (MC-4) receptor agonists and melanin concentrating hormone (MCH) receptor-1 antagonists.

  2009cites this paper
• Animals models of MCH function and what they can tell us about its role in energy balance.

  2009cites this paper