cDNA Clones for Liver Cytochrome P-450s from Individual Aroclor-Treated Rats: Constitutive Expression of a New P-450 Gene Related to Phenobarbital-Inducible Forms

No abstract is available for this paper.

• Publication year

  1986

• Venue

  DNA

• Publication date

  1986-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/dna.1986.5.209PMID 3013548
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genes for cytochrome P-450 and their regulation.

  1986cited by this paper
• Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid.

  1985cited by this paper
• Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes.

  1985cited by this paper
• Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat.

  1985cited by this paper
• Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver.

  1985cited by this paper
• The complete amino acid sequence of a constitutive form of liver microsomal cytochrome P-450.

  1985cited by this paper
• Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family.

  1985cited by this paper
• Differential induction and tissue-specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene family.

  1984cited by this paper
• Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC.

  1984cited by this paper
• Segmental homologies in the coding and 3' non-coding sequences of rat liver cytochrome P-450e and P-450b cDNAs and cytochrome P-450e-like genes.

  1984influential reference
• Characterization of complementary DNA clones coding for two forms of 3-methylcholanthrene-inducible rat liver cytochrome P-450.

  1984cited by this paper
• Distinct organization of methylcholanthrene- and phenobarbital-inducible cytochrome P-450 genes in the rat.

  1984cited by this paper
• Microheterogeneity in a cytochrome P-450 multigene family

  1984influential reference
• A comprehensive set of sequence analysis programs for the VAX

  1984cited by this paper
• Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver.

  1984cited by this paper
• Molecular cloning of a complementary DNA to 3-methylcholanthrene-inducible cytochrome P-450 mRNA from rat liver.

  1983cited by this paper
• Mutagenic response of Ames strains cured of their inducible Fels 1 and Fels 2 prophages.

  1983cited by this paper
• Regulation of cytochrome P-450. Immunochemical quantitation of eight isozymes in liver microsomes of rats treated with polybrominated biphenyl congeners.

  1983cited by this paper
• Structural characteristics of cytochrome P-450. Possible location of the heme-binding cysteine in determined amino-acid sequences.

  1983cited by this paper
• Molecular induction by phenobarbital of a rat hepatic form of cytochrome P-450: expression of a 4-kilobase messenger RNA.

  1983cited by this paper
• Cloned cytochrome P-450 cDNA. Nucleotide sequence and homology to multiple phenobarbital-induced mRNA species.

  1983cited by this paper
• Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.

  1983cited by this paper
• Cloning and sequence analysis of a rat liver cDNA coding for a phenobarbital-inducible microheterogenous cytochrome P-450 variant: regulation of its messenger level by xenobiotics.

  1983cited by this paper
• Induction of two immunochemically related rat liver cytochrome P-450 isozymes, cytochromes P-450c and P-450d, by structurally diverse xenobiotics.

  1983cited by this paper
• A cytochrome P-450 multigene family. Characterization of a gene activated by phenobarbital administration.

  1983influential reference
• At least six forms of extremely homologous cytochromes P-450 in rat liver are encoded at two closely linked genetic loci.

  1983influential reference
• Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver.

  1982cited by this paper
• Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genes.

  1982influential reference
• A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments.

  1982cited by this paper
• The filamentous phage (Ff) as vectors for recombinant DNA--a review.

  1982cited by this paper
• Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

  1982cited by this paper
• Molecular cloning of cDNA for the alpha, beta, and gamma chains of rat fibrinogen. A family of coordinately regulated genes.

  1981cited by this paper
• Construction and identification of a hybrid plasmid containing DNA sequence complementary to phenobarbital-inducible cytochrome P-450 messenger RNA from rat liver.

  1981cited by this paper
• Amino acid sequence of an analogous peptide from two forms of cytochrome P-450.

  1981cited by this paper
• Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

  1980influential reference
• Sequencing end-labeled DNA with base-specific chemical cleavages.

  1980cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• The Ah locus: genetic regulation of the metabolism of carcinogens, drugs, and other environmental chemicals by cytochrome P-450-mediated monooxygenases.

  1979cited by this paper
• Increase in level of functional messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) during induction by cyclic adenosine 3':5'-monophosphate.

  1977cited by this paper
• Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

  1977cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper

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  2015cites this paper
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  2006cites this paper
• Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.

  2004cites this paper
• Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

  2004cites this paper
• Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells.

  2002cites this paper
• Acute sodium arsenite administration induces pulmonary CYP1A1 mRNA, protein and activity in the rat

  2002cites this paper
• Unaltered expression of multidrug resistance transporters in polycyclic aromatic hydrocarbon-resistant rat liver cells.

  2001cites this paper
• Differential effects of oltipraz on CYP1A and CYP2B in rat lung.

  2001cites this paper
• Nominal Growth Hormone Pulses in Otherwise Normal Masculine Plasma Profiles Induce Intron Retention of Overexpressed Hepatic CYP2C11 with Associated Nuclear Splicing Deficiency* * This work was supported by NIH Grants GM-45758 and HD-16358.

  2000cites this paper
• Nominal growth hormone pulses in otherwise normal masculine plasma profiles induce intron retention of overexpressed hepatic CYP2C11 with associated nuclear splicing deficiency.

  2000cites this paper
• Endotoxin suppresses the oltipraz‐mediated induction of major hepatic glutathione transferases and cytochromes P450 in the rat

  1998cites this paper
• Induction of multidrug resistance gene expression in rat liver cells in response to acute treatment by the DNA-damaging agent methyl methanesulfonate.

  1998cites this paper
• Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture.

  1997cites this paper
• Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes.

  1997cites this paper
• Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment.

  1997cites this paper
• Identification of CYP2B14P and CYP2B16P, two apparent pseudogenes in the rat cytochrome P450 2B (CYP2B) subfamily.

  1996cites this paper
• A comparison of the effect of inducers on the expression of glutathione‐S‐transferases in the liver of the intact rat and in hepatocytes in primary culture

  1996cites this paper
• P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment.

  1996cites this paper
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  1996cites this paper
• Differential regulation of mdr genes in response to 2-acetylaminofluorene treatment in cultured rat and human hepatocytes.

  1996cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994influential citation
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1992cites this paper
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  1992cites this paper
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  1991cites this paper
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  1991cites this paper
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  1991cites this paper
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  1990cites this paper
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  1990cites this paper
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  1990cites this paper
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  1989cites this paper
• Phenobarbital-inducible gene expression in developing rat liver: relationship to hepatocyte function.

  1989cites this paper
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  1989cites this paper
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  1989cites this paper
• Heme may not be a positive regulator of cytochrome-P450 gene expression.

  1989cites this paper
• EFFECT OF HAEM ON CYTOCHROME P‐450 SYNTHESIS

  1989cites this paper
• Cloning of rodent cDNA coding the poly(ADP-ribose) polymerase catalytic domain and analysis of mRNA levels during the cell cycle.

  1989cites this paper
• Olfactory-specific cytochrome P-450. cDNA cloning of a novel neuroepithelial enzyme possibly involved in chemoreception.

  1989cites this paper
• Expression of cytochrome P-450 isozymes in the liver of hypophysectomized rats. Evidence for different regulation mechanisms concerning P450IIB and P450IIIA subfamilies.

  1988cites this paper
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  1988cites this paper
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  1988cites this paper
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  1988cites this paper
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  1988influential citation
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  1988cites this paper
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  1988cites this paper
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  1988cites this paper
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  1987cites this paper
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  1987cites this paper
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  1987cites this paper
• Molecular Mechanisms Regulating ACTH Synthesis and Release a

  1987cites this paper
• P450 genes: structure, evolution, and regulation.

  1987cites this paper
• Isolation and characterization of cDNA clones for cytochromes P-450 immunochemically related to rat hepatic P-450 form PB-1.

  1986cites this paper