Regulation of rat alveolar type 2 cell proliferation in vitro involves type II cAMP-dependent protein kinase.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPLUNG.00049.2006PMID 16980378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins.

  2005cited by this paper
• cAMP-PKA signaling to the mitochondria: protein scaffolds, mRNA and phosphatases.

  2005cited by this paper
• Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera.

  2004cited by this paper
• Localized effects of cAMP mediated by distinct routes of protein kinase A.

  2004cited by this paper
• Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry

  2003cited by this paper
• AKAP mediated signal transduction.

  2003cited by this paper
• Respiratory Research BioMed Central Review Measuring the lung function in the mouse: the challenge of size

  2003cited by this paper
• Epac: a new cAMP target and new avenues in cAMP research

  2003cited by this paper
• PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

  2002cited by this paper
• Heparin inhibits DNA synthesis and gene expression in alveolar type II cells.

  2002cited by this paper
• Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis.

  2001cited by this paper
• Cyclic AMP signalling.

  2001cited by this paper
• Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein

  2001cited by this paper
• Persistent versus transient map kinase (ERK) activation in the proliferation of lung epithelial type 2 cells.

  2001cited by this paper
• Molecular regulation of lung development.

  2001cited by this paper
• The Localization and Activity of cAMP-dependent Protein Kinase Affect Cell Cycle Progression in Thyroid Cells*

  2000influential reference
• Specificity in the cAMP/PKA signaling pathway. differential expression, regulation, and subcellular localization of subunits of PKA.

  2000cited by this paper
• The molecular basis of lung morphogenesis.

  2000cited by this paper
• Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding.

  2000cited by this paper
• Characterization of a Novel Giant Scaffolding Protein, CG-NAP, That Anchors Multiple Signaling Enzymes to Centrosome and the Golgi Apparatus*

  1999cited by this paper
• AKAPs: from structure to function.

  1999cited by this paper
• cAMP-dependent positive control of cyclin A2 expression during G1/S transition in primary hepatocytes.

  1999cited by this paper
• Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A.

  1999cited by this paper
• Mitosis-specific Phosphorylation and Subcellular Redistribution of the RIIα Regulatory Subunit of cAMP-dependent Protein Kinase*

  1998cited by this paper
• Cyclic AMP-dependent protein kinase (PKA) gene expression is developmentally regulated in fetal lung.

  1998cited by this paper
• Marker genes of decidualization: activation of the decidual prolactin gene.

  1998cited by this paper
• Localization of cAMP-dependent signal transducers in early rat liver carcinogenesis

  1998cited by this paper
• The RIα subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-Receptor

  1997cited by this paper
• Cell cycle kinetics in the alveolar epithelium.

  1997cited by this paper
• Transcriptional regulation by cyclic AMP.

  1997cited by this paper
• Cyclic AMP negatively controls c-myc transcription and G1 cell cycle progression in p210 BCR-ABL transformed cells: inhibitory activity exerted through cyclin D1 and cdk4

  1997cited by this paper
• Expression of CYP2B1 in freshly isolated and proliferating cultures of epithelial rat lung cells.

  1996cited by this paper
• Cloning and Characterization of A-kinase Anchor Protein 100 (AKAP100)

  1995cited by this paper
• The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.

  1994cited by this paper
• The RI alpha subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.

  1994cited by this paper
• Pulmonary epithelial cell proliferation in primary culture of alveolar type II cells.

  1993cited by this paper
• Flow cytometric analysis of the expression of PCNA during the cell cycle in HeLa cells and effects of the inhibition of DNA synthesis on it.

  1993cited by this paper
• Down‐regulation of riα subunit of camp‐dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c‐ha‐ras and c‐erbb‐2 proto‐oncogenes

  1993cited by this paper
• The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional-related diseases.

  1993cited by this paper
• 8-Cl-cAMP induces truncation and down-regulation of the RI alpha subunit and up-regulation of the RII beta subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells.

  1993cited by this paper
• Association of type II cAMP-dependent protein kinase with p34cdc2 protein kinase in human fibroblasts.

  1991cited by this paper
• Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin.

  1990influential reference
• Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: new approaches to therapy.

  1990cited by this paper
• The expression of cAMP-dependent protein kinase subunits in primary rat hepatocyte cultures. Cyclic AMP down-regulates its own effector system by decreasing the amount of catalytic subunit and increasing the mRNAs for the inhibitory (R) subunits of cAMP-dependent protein kinase.

  1990cited by this paper
• An antisense oligodeoxynucleotide targeted against the type II beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects.

  1990cited by this paper
• 8-Chloro-cAMP inhibits transforming growth factor alpha transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation.

  1990cited by this paper
• Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain.

  1989cited by this paper
• Role of cyclic AMP in proliferation of lung tissue in organ culture.

  1989cited by this paper
• A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

  1989cited by this paper
• Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.

  1989cited by this paper
• Protein serine/threonine kinases.

  1987cited by this paper
• Involvement of cAMP and cAMP-dependent protein kinase in the initiation of DNA synthesis by rat liver cells.

  1981cited by this paper
• A possible involvement of type II cAMP-dependent protein kinase in the initiation of DNA synthesis by rat liver cells.

  1980cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues.

  1977cited by this paper
• Flow microfluorometric analysis of nuclear DNA in cells from solid tumors and cell suspensions

  1977cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Inhaled b 2 Adrenergic Agonists and Other cAMP-Elevating Agents: Therapeutics for Alveolar Injury and Acute Respiratory Disease Syndrome?

  2022cites this paper
• Prkg2 regulates alveolar type 2-mediated re-alveolarization

  2022cites this paper
• Inhaled β2 Adrenergic Agonists and Other cAMP-Elevating Agents: Therapeutics for Alveolar Injury and Acute Respiratory Disease Syndrome?

  2021cites this paper
• Biotransformation enzymes and lung cell response to 2-hydroxyethyl-methacrylate.

  2012cites this paper
• Proteomic analysis of hepatitis C virus (HCV) core protein transfection and host regulator PA28γ knockout in HCV pathogenesis: a network-based study.

  2012cites this paper
• TACE/TGF-α/EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components

  2011cites this paper
• Balance of life and death in alveolar epithelial type II cells: proliferation, apoptosis, and the effects of cyclic stretch on wound healing.

  2011cites this paper
• Unraveling the intricacies of spatial organization of the ErbB receptors and downstream signaling pathways

  2009cites this paper
• Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair.

  2009cites this paper
• Mechanical stretch decreases migration of alveolar epithelial cells through mechanisms involving Rac1 and Tiam1.

  2008cites this paper