Regenerative Growth of Corticospinal Tract Axons via the Ventral Column after Spinal Cord Injury in Mice

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Neuroscience

• Publication date

  2008-07-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1523/JNEUROSCI.5372-07.2008PMID 18596159PMCID PMC2745399
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice.

  2008cited by this paper
• CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure.

  2008cited by this paper
• Nonsteroidal Anti-Inflammatory Drugs Promote Axon Regeneration via RhoA Inhibition

  2007cited by this paper
• Response to Correspondence: Kim et al., “Axon Regeneration in Young Adult Mice Lacking Nogo-A/B.” Neuron 38, 187–199

  2007cited by this paper
• Response to: Kim et al., "axon regeneration in young adult mice lacking Nogo-A/B." Neuron 38, 187-199.

  2007cited by this paper
• Textbook of Neural Repair and Rehabilitation: Anatomical and biochemical plasticity of neurons: regenerative growth of axons, sprouting, pruning, and denervation supersensitivity

  2006cited by this paper
• Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?

  2006cited by this paper
• Experimental strategies to promote spinal cord regeneration--an integrative perspective.

  2006cited by this paper
• Genetic mouse models for studying inhibitors of spinal axon regeneration.

  2006cited by this paper
• Glial inhibition of CNS axon regeneration

  2006cited by this paper
• Nogo-A-Deficient Mice Reveal Strain-Dependent Differences in Axonal Regeneration

  2006cited by this paper
• Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury

  2005cited by this paper
• Nogo‐A antibody improves regeneration and locomotion of spinal cord–injured rats

  2005cited by this paper
• The Nogo signaling pathway for regeneration block.

  2004cited by this paper
• Regeneration beyond the glial scar

  2004cited by this paper
• The dorsolateral corticospinal tract in mice: An alternative route for corticospinal input to caudal segments following dorsal column lesions

  2004cited by this paper
• The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats

  2004cited by this paper
• Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord.

  2003cited by this paper
• Axon regeneration in young adult mice lacking Nogo-A/B.

  2003influential reference
• Lack of enhanced spinal regeneration in Nogo-deficient mice.

  2003cited by this paper
• Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury

  2003influential reference
• Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

  2003cited by this paper
• False resurrections: Distinguishing regenerated from spared axons in the injured central nervous system

  2003cited by this paper
• Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury

  2003cited by this paper
• A New Millenium for Spinal Cord Regeneration: Growth-Associated Genes

  2002cited by this paper
• Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury

  2001cited by this paper
• Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses.

  2001cited by this paper
• Ipsilateral, ventral corticospinal tract of the adult rat: Ultrastructure, myelination and synaptic connections

  2000cited by this paper
• Regeneration of Lesioned Corticospinal Tract Fibers in the Adult Rat Induced by a Recombinant, Humanized IN-1 Antibody Fragment

  2000cited by this paper
• Influence of the axotomy to cell body distance in rat rubrospinal and spinal motoneurons: Differential regulation of GAP‐43, tubulins, and neurofilament‐M

  1999cited by this paper
• Robust Regeneration of Adult Sensory Axons in Degenerating White Matter of the Adult Rat Spinal Cord

  1999cited by this paper
• Repairing the damaged spinal cord.

  1999cited by this paper

• SpinalTRAQ: A Novel Pipeline for Volumetric Cervical Spinal Cord Analysis Identifies the Corticospinal Tract Synaptic Projectome in Healthy and Post-stroke Mice

  2025cites this paper
• Schwann Cells and Their Exosomes: Research Progress and Prospect in Spinal Cord Injury

  2025cites this paper
• Spontaneously regenerative corticospinal neurons in mice

  2024cites this paper
• Biomaterial-mediated delivery of traditional Chinese medicine ingredients for spinal cord injury: a systematic review

  2024cites this paper
• SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice

  2024cites this paper
• Combination of Engineered Expression of Polysialic Acid on Transplanted Schwann Cells and in Injured Rat Spinal Cord Promotes Significant Axonal Growth and Functional Recovery

  2023cites this paper
• A spatially specified systems pharmacology therapy for axonal recovery after injury

  2023cites this paper
• Exosomal microRNAs have great potential in the neurorestorative therapy for traumatic brain injury.

  2022cites this paper
• biPACT: a method for three-dimensional visualization of mouse spinal cord circuits of long segments with high resolution

  2021cites this paper
• The Necessity of Vesicle-Associated Membrane Protein Expression by NG2 Glia for Maintenance of Glial and Neuronal Health

  2021cites this paper
• Therapeutic Effect of BDNF-Overexpressing Human Neural Stem Cells (F3.BDNF) in a Contusion Model of Spinal Cord Injury in Rats

  2021cites this paper
• Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury

  2021cites this paper
• Spinal Cord Imaging Markers and Recovery of Volitional Leg Movement With Spinal Cord Epidural Stimulation in Individuals With Clinically Motor Complete Spinal Cord Injury

  2020cites this paper
• Rostro-caudal specificity of corticospinal tract projections in mice

  2020cites this paper
• In-Depth Characterization of Layer 5 Output Neurons of the Primary Somatosensory Cortex Innervating the Mouse Dorsal Spinal Cord

  2020cites this paper
• Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury.

  2020cites this paper
• Molecular Mechanisms of Central Nervous System Axonal Regeneration and Remyelination: A Review

  2020cites this paper
• [Development of New Therapies for Neurodegenerative Diseases via Axonal Growth].

  2019cites this paper
• High-resolution 3D imaging and analysis of axon regeneration in unsectioned spinal cord with or without tissue clearing

  2019cites this paper
• Enhanced axonal transport: A novel form of “plasticity” after primate and rodent spinal cord injury

  2018cites this paper
• Protective effect of Lithium on Schwann cell transplantation via Wnt / β-catenin signaling pathway after spinal cord injury in vitro and vivo

  2018cites this paper
• Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1

  2018cites this paper
• Taxol-modified collagen scaffold implantation promotes functional recovery after long-distance spinal cord complete transection in canines.

  2018cites this paper
• Rodent spinal cord injury models for studies of axon regeneration

  2017cites this paper
• The crossed phrenic phenomenon

  2017influential citation
• Acute Ischemic Stroke 2 adopt the function of neural tissue destroyed by ischemia

  2017cites this paper
• Adaptive Plasticity After Focal Ischemic Stroke

  2017cites this paper
• Variable laterality of corticospinal tract axons that regenerate after spinal cord injury as a result of PTEN deletion or knock‐down

  2016cites this paper
• Neuroprotective and Neurorestorative Processes after Spinal Cord Injury: The Case of the Bulbospinal Respiratory Neurons

  2016cites this paper
• The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.

  2015influential citation
• Investigating local circuit function following spinal cord injury and cell transplant therapy

  2015cites this paper
• Randomized, Crossover Study Respiratory Neuromechanical Outputs in Humans? A Double-Blind, Sham-Controlled, Does Trans-Spinal Direct Current Stimulation Alter Phrenic Motoneurons and

  2015cites this paper
• Local Injection of Lenti–BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice

  2015cites this paper
• Regeneration and plasticity of descending propriospinal neurons after transplantation of Schwann cells overexpressing glial cell line-derived neurotrophic factor following thoracic spinal cord injury in adult rats

  2015cites this paper
• Schwann cell transplantation and descending propriospinal regeneration after spinal cord injury.

  2015cites this paper
• Nonspecific labeling limits the utility of Cre‐Lox bred CST‐YFP mice for studies of corticospinal tract regeneration

  2015cites this paper
• Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice

  2015cites this paper
• Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1−/− Mice

  2015influential citation
• Thinking outside the brain: structural plasticity in the spinal cord promotes recovery from cortical stroke.

  2014cites this paper
• Activation of Akt/FKHR in the medulla oblongata contributes to spontaneous respiratory recovery after incomplete spinal cord injury in adult rats.

  2014influential citation
• Use of Self-Complementary Adeno-Associated Virus Serotype 2 as a Tracer for Labeling Axons: Implications for Axon Regeneration

  2014cites this paper
• Gait Control and Locomotor Recovery after Spinal Cord Injury

  2014cites this paper
• Neuroprosthetic rehabilitation and translational mechanism after severe spinal cord injury

  2014cites this paper
• Textbook of Neural Repair and Rehabilitation: Degenerative changes and reactive growth responses of neurons following denervation and axotomy: historical concepts and their modern embodiments

  2014cites this paper
• Exercise Training after Spinal Cord Injury Selectively Alters Synaptic Properties in Neurons in Adult Mouse Spinal Cord

  2013cites this paper
• The Ryk Receptor Is Expressed in Glial and Fibronectin-Expressing Cells after Spinal Cord Injury

  2013cites this paper
• Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter.

  2013influential citation
• Novel Use of Dual Anti-Inflammatory Therapy to Overcome Drug Resistance and Improve Functional Recovery Following Spinal Cord Injury

  2012cites this paper
• Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

  2012cites this paper
• p53 Regulates the Neuronal Intrinsic and Extrinsic Responses Affecting the Recovery of Motor Function following Spinal Cord Injury

  2012influential citation
• Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-³H-aspartic acid.

  2012cites this paper
• Single Collateral Reconstructions Reveal Distinct Phases of Corticospinal Remodeling after Spinal Cord Injury

  2012cites this paper
• Concepts and methods for the study of axonal regeneration in the CNS.

  2012cites this paper
• Biotinylated dextran amine anterograde tracing of the canine corticospinal tract

  2012cites this paper
• Extensive respiratory plasticity after cervical spinal cord injury in rats: axonal sprouting and rerouting of ventrolateral bulbospinal pathways.

  2012cites this paper
• Replication and reproducibility in spinal cord injury research.

  2012cites this paper
• Diaschisis, Degeneration, and Adaptive Plasticity After Focal Ischemic Stroke

  2012cites this paper
• c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.

  2011cites this paper
• Syndromics: A Bioinformatics Approach for Neurotrauma Research

  2011cites this paper
• Changes in CNS structures after spinal cord lesions implications for BMI.

  2011cites this paper
• Caltubin, a Novel Molluscan Tubulin-Interacting Protein, Promotes Axonal Growth and Attenuates Axonal Degeneration of Rodent Neurons

  2011cites this paper
• PTEN Deletion Enhances the Regenerative Ability of Adult Corticospinal Neurons

  2010cites this paper
• Cough following low thoracic hemisection in the cat.

  2010cites this paper
• Co-transplantation of olfactory ensheathing glia and mesenchymal stromal cells does not have synergistic effects after spinal cord injury in the rat.

  2010cites this paper
• Regenerated synapses in lamprey spinal cord are sparse and small even after functional recovery from injury

  2010cites this paper
• Paired Immunoglobulin-like Receptor B Knockout Does Not Enhance Axonal Regeneration or Locomotor Recovery after Spinal Cord Injury*

  2010cites this paper
• Assessing spinal axon regeneration and sprouting in Nogo-, MAG-, and OMgp-deficient mice.

  2010cites this paper
• Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord

  2010cites this paper
• Acute Care in Cervical Spinal Cord Trauma with Long-Term Benefit: A Review

  2009cites this paper
• Intrinsic regenerative mechanisms of central nervous system neurons.

  2009cites this paper
• Descending bulbospinal pathways and recovery of respiratory motor function following spinal cord injury.

  2009cites this paper
• Effect of cervical spinal cord hemisection on the expression of axon growth markers.

  2009cites this paper
• Targeting a dominant negative rho kinase to neurons promotes axonal outgrowth and partial functional recovery after rat rubrospinal tract lesion.

  2009cites this paper
• A re-assessment of the effects of a Nogo-66 receptor antagonist on regenerative growth of axons and locomotor recovery after spinal cord injury in mice.

  2008cites this paper