Antioxidant Constituents from the Bark of Aglaia eximia (Meliaceae)

J. Sianturi,K. Farabi,T. Mayanti,D. Harneti,Darwati Darwati,U. Supratman,K. Awang,H. Hayashi

Published 2016 in Makara Journal of Science

ABSTRACT

The genus Aglaia is a a rich source of different compounds with interesting biological activities. A part of our continuing search for novel biologically active compounds from Indonesia Aglaia plants, the ethyl acetate extract of bark of Aglaia eximia showed significant antioxidant activity. Four antioxidant compounds, kaempferol ( 1 ), kaempferol-3- O- α-L-rhamnoside (2), kaempferol-3- O- β-D-glucoside (3) and kaempferol-3- O -β-D-glucosyl-(1→4)-α-L-rhamnoside (4) were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of compounds 1 - 4 were identified on the basis of spectroscopic datas including  UV, IR, NMR and MS along with by comparison with those spectra datas previously reported. All compounds showed DPPH radical-scavenging activity with IC 50 values of  1.18, 6.34, 8.17, 10.63 m g/mL, respectively.

PUBLICATION RECORD

  • Publication year

    2016

  • Venue

    Makara Journal of Science

  • Publication date

    2016-03-31

  • Fields of study

    Medicine, Chemistry, Environmental Science

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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REFERENCES

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