The genus Aglaia is a a rich source of different compounds with interesting biological activities. A part of our continuing search for novel biologically active compounds from Indonesia Aglaia plants, the ethyl acetate extract of bark of Aglaia eximia showed significant antioxidant activity. Four antioxidant compounds, kaempferol ( 1 ), kaempferol-3- O- α-L-rhamnoside (2), kaempferol-3- O- β-D-glucoside (3) and kaempferol-3- O -β-D-glucosyl-(1→4)-α-L-rhamnoside (4) were isolated from the bark of Aglaia eximia (Meliaceae). The chemical structures of compounds 1 - 4 were identified on the basis of spectroscopic datas including UV, IR, NMR and MS along with by comparison with those spectra datas previously reported. All compounds showed DPPH radical-scavenging activity with IC 50 values of 1.18, 6.34, 8.17, 10.63 m g/mL, respectively.
Antioxidant Constituents from the Bark of Aglaia eximia (Meliaceae)
J. Sianturi,K. Farabi,T. Mayanti,D. Harneti,Darwati Darwati,U. Supratman,K. Awang,H. Hayashi
Published 2016 in Makara Journal of Science
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- Publication year
2016
- Venue
Makara Journal of Science
- Publication date
2016-03-31
- Fields of study
Medicine, Chemistry, Environmental Science
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