Methodologic problems in clinical trials in heart failure.

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Journal of Chronic Diseases

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/0021-9681(85)90081-5PMID 3998050
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Acute hemodynamic and long-term clinical effects of prazosin in the treatment of chronic congestive heart failure.

  2009cited by this paper
• Sustained effect of hydralazine in long term treatment of CHF.

  2009cited by this paper
• A placebo-controlled trial of captopril in refractory chronic congestive heart failure. Captopril Multicenter Research Group.

  1983cited by this paper
• Efficacy of prazosin in the management of chronic congestive heart failure: a 6-month randomized, double-blind, placebo-controlled study.

  1983cited by this paper
• Long-term ambulatory therapy with prazosin versus placebo for chronic heart failure: relation between clinical response and left ventricular function at rest and during exercise.

  1983cited by this paper
• Improved Exercise Capacity and Differing Arterial and Venous Tolerance During Chronic Isosorbide Dinitrate Therapy for Congestive Heart Failure

  1983cited by this paper
• Controlled Trial of Captopril in Chronic Heart Failure: A Rest and Exercise Hemodynamic Study

  1983cited by this paper
• Hemodynamic patterns of response during long-term captopril therapy for severe chronic heart failure.

  1983cited by this paper
• Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure.

  1982cited by this paper
• Clinical and hemodynamic improvement of congestive heart failure by long-term vasodilator therapy with postjunctional alpha 1-adrenoceptor blockade.

  1982cited by this paper
• Acute and long-term effects of captopril on exercise cardiac performance and exercise capacity in congestive heart failure.

  1982cited by this paper
• Long-term hemodynamic and clinical efficacy of captopril therapy in ambulatory management of severe chronic congestive heart failure.

  1982cited by this paper
• Long-term captopril therapy in congestive heart failure: serial hemodynamic and echocardiographic changes.

  1982cited by this paper
• Pitfalls in the serial assessment of cardiac functional status. How a reduction in "ordinary" activity may reduce the apparent degree of cardiac compromise and give a misleading impression of improvement.

  1982cited by this paper
• Hemodynamic characterization of tolerance to long-term hydralazine therapy in severe chronic heart failure.

  1982cited by this paper
• Acute and long-term effects of captopril on exercise cardiac performance and exercise capacity in congestive heart failure.

  1982cited by this paper
• Heart failure in outpatients: a randomized trial of digoxin versus placebo.

  1982cited by this paper
• Is digoxin really important in treatment of compensated heart failure? A placebo-controlled crossover study in patients with sinus rhythm.

  1982cited by this paper
• Hydralazine in the long-term treatment of chronic heart failure: lack of difference from placebo.

  1982cited by this paper
• Increase in plasma norepinephrine during prazosin therapy for chronic congestive heart failure.

  1981cited by this paper
• Therapeutic efficacy or oral pirbuterol in severe chronic congestive heart failure: acute hemodynamic and long-term ambulatory evaluation.

  1981cited by this paper
• Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure.

  1981cited by this paper
• The pharmacokinetic, pharmacodynamic and haemodynamic effects of acute and chronic alpha-adrenoceptor blockade in chronic heart failure.

  1981cited by this paper
• Acute and Long‐term Effects of Vasodilator Therapy on Resting and Exercise Hemodynamics and Exercise Tolerance

  1981cited by this paper
• Comparative Reproducibility and Validity of Systems for Assessing Cardiovascular Functional Class: Advantages of a New Specific Activity Scale

  1981cited by this paper
• Acute and chronic effects of pirbuterol on left ventricular ejection fraction and clinical status in severe congestive heart failure.

  1981cited by this paper
• Metabolic Assessment of Exercise in Chronic Heart Failure Patients: Treated with Short–term Vasodilators

  1980cited by this paper
• Oral hydralazine in chronic heart failure: sustained beneficial hemodynamic effects.

  1980cited by this paper
• Exercise Capacity in Patients with Severe Left Ventricular Dysfunction

  1980cited by this paper
• Acute and Long‐term Response to an Oral Converting‐enzyme Inhibitor, Captopril, in Congestive Heart Failure

  1980cited by this paper
• Improved exercise ejection fraction with long-term prazosin therapy in patients with heart failure.

  1980cited by this paper
• Acute and chronic effects of oral hydralazine on left ventricular pump function and renal hemodynamics in chronic left heart failure.

  1980cited by this paper
• Sustained hemodynamic effects without tolerance during long-term isosorbide dinitrate treatment of chronic left ventricular failure.

  1980cited by this paper
• The acute and chronic haemodynamic effects of prazosin in severe congestive cardiac failure.

  1980cited by this paper
• Long-term therapy of heart failure with prazosin: a randomized double blind trial.

  1980cited by this paper
• Low-dose captopril in chronic heart failure: acute haemodynamic effects and long-term treatment.

  1980cited by this paper
• Contrasting immediate and long-term effects of isosorbide dinitrate on exercise capacity in congestive heart failure.

  1980cited by this paper
• Hydralazine in the management of left ventricular failure.

  1979cited by this paper
• Effect of Prazosin vs Placebo on Chronic Left Ventricular Heart Failure

  1979cited by this paper
• Marked early attenuation of hemodynamic effects of oral prazosin therapy in chronic congestive heart failure.

  1979cited by this paper
• Reliability and Validity Assessment

  1979cited by this paper
• Immediate Effects of Hydralazine-Isosorbide Dinitrate Combination on Exercise Capacity and Exercise Hemodynamics in Patients with Left Ventricular Failure

  1979cited by this paper
• Effect of isosorbide dinitrate on response to submaximal and maximal exercise in patients with congestive heart failure.

  1979cited by this paper
• Attenuation of prazosin effect on cardiac output in chronic heart failure.

  1979cited by this paper
• Paradox of improved exercise but not resting hemodynamics with short-term prazosin in chronic heart failure.

  1979cited by this paper
• Functional capacity of patients with chronic left ventricular failure. Relationship of bicycle exercise performance to clinical and hemodynamic characterization.

  1979cited by this paper
• Nitrate therapy for congestive heart failure.

  1978cited by this paper
• Nitrate Therapy for Congestive Heart Failure

  1978cited by this paper
• Hemodynamic improvement after oral hydralazine in left ventricular failure: a comparison with nitroprusside infusion in 16 patients.

  1977cited by this paper
• Efficacy of Ambulatory Systemic Vasodilator Therapy with Oral Prazosin in Chronic Refractory Heart Failure: Concomitant Relief of Pulmonary Congestion and Elevation of Pump Output Demonstrated by Improvements in Symptomatology, Exercise Tolerance, Hemodynamics and Echocardiography

  1977cited by this paper
• Measurement of functional capacity with visual analogue scales.

  1977cited by this paper
• Sustained haemodynamic action of nitroglycerin ointment.

  1976cited by this paper
• The reliability of clinical methods, data and judgments (first of two parts).

  1975cited by this paper
• Hemodynamic and metabolic effects of isosorbide dinitrate in chronic congestive heart failure.

  1975cited by this paper
• Letter: Reye's syndrome.

  1975cited by this paper
• The reliability of clinical methods, data and judgments (second of two parts).

  1975cited by this paper
• Hemodynamic Effects of Orally Administered Isosorbide Dinitrate in Patients with Congestive Heart Failure

  1974cited by this paper
• Case 16391: Sudden Aging in a Man of Seventy-Six

  1930cited by this paper
• Case 16402: Inexcusable Delay. Whose Fault Was It?

  1930cited by this paper

• Health-Related Quality of Life and Associated Factors Among Adult Patients With Heart Failure in Tertiary Hospitals, Tigray Region, Northern Ethiopia, 2020.

  2021cites this paper
• Drugs for Heart Failure

  2020cites this paper
• Montelukast for prevention and treatment of asthma exacerbations in adults: Systematic review and meta-analysis.

  2014cites this paper
• Cancer Pain: Understanding clinical trials in pain research

  2009cites this paper
• Pharmacological management to reduce exacerbations in adults with asthma: a systematic review and meta-analysis.

  2004cites this paper
• Why different trials on digitalis give conflicting data

  2004cites this paper
• Understanding clinical trials in pain research

  2003cites this paper
• The SWAL-QOL Outcomes Tool for Oropharyngeal Dysphagia in Adults: I. Conceptual Foundation and Item Development

  2000cites this paper
• The congestion score: a simple tool for a complicated disease?

  2000cites this paper
• A Review of Quality-of-Life Evaluations in Patients with Congestive Heart Failure

  1999cites this paper
• Health status assessment methods for adults: past accomplishments and future challenges.

  1999cites this paper
• Methods of assessing the impact of climacteric complaints on quality of life.

  1998cites this paper
• Health-Related Quality of Life

  1998cites this paper
• Classification of heart failure in population based research: An assessment of six heart failure scores

  1997cites this paper
• Outcomes for Older Men and Women with Congestive Heart Failure

  1997cites this paper
• Measurement of quality of life in patients with ischemic disease of the heart or brain

  1996cites this paper
• Extended therapy with ipratropium is associated with improved lung function in patients with COPD. A retrospective analysis of data from seven clinical trials.

  1996cites this paper
• A comparison of quality of life scores in patients with angina pectoris after angioplasty compared with after medical therapy. Outcomes of a randomized clinical trial. Veterans Affairs Study of Angioplasty Compared to Medical Therapy Investigators.

  1995cites this paper
• A Comparison of Quality of Life Scores in Patients With Angina Pectoris After Angioplasty Compared With After Medical Therapy Outcomes of a Randomized Clinical Trial

  1995cites this paper
• A comparison of three quality of life instruments in subjects with angina pectoris: the Sickness Impact Profile, the Nottingham Health Profile, and the Quality of Well Being Scale.

  1994cites this paper
• Establishing and Evaluating Clinical Pharmacy Services in Primary Care

  1994cites this paper
• [Digoxin is effective in th treatment of patients with heart failure and sinus rhythm].

  1994cites this paper
• How do changes in lifestyle complement medical treatment in heart failure?

  1994cites this paper
• Quality of life and cardiovascular medication

  1994cites this paper
• Quality of life in cardiovascular disease.

  1993cites this paper
• Methods for assessing quality of life in the Cardiac Arrhythmia Suppression Trial (CAST)

  1992cites this paper
• Heart Failure Mechanisms and Management

  1992cites this paper
• Assessment of patients with clinical congestive heart failure: Ventilatory threshold or aerobic power determination?

  1991cites this paper
• A summary index for the assessment of quality of life in angina pectoris.

  1991cites this paper
• Comparison of perceived health status and conventional functional evaluation in stable patients with coronary artery disease.

  1991cites this paper
• Cardiac failure: symptoms and functional status.

  1991cites this paper
• Quality of life in cardiovascular diseases. Emphasis on beta-blocker treatment.

  1991cites this paper
• The relationship between exercise tolerance and quality of life in angina pectoris

  1991cites this paper
• Exercise Testing and Training of Patients with Congestive Heart Failure and Left Ventricular Dysfunction

  1991cites this paper
• To what extent do congestive heart failure patients in sinus rhythm benefit from digoxin therapy? A systematic overview and meta-analysis.

  1990cites this paper
• Factors of importance when evaluating quality of life in clinical trials.

  1990cites this paper
• Centrally Acting Sympatholytic Agents in the Treatment of Congestive Heart Failure

  1990cites this paper
• CNS-related subjective symptoms during treatment with beta 1-adrenoceptor antagonists (atenolol, metoprolol): two double-blind placebo controlled studies.

  1989cites this paper
• Development and testing of a new measure of health status for clinical trials in heart failure

  1989cites this paper
• Quality of life: can it and should it be assessed in patients with heart failure?

  1989cites this paper
• A controlled trial of digoxin in congestive heart failure.

  1988cites this paper
• Measurement of the quality of life in congestive heart failure-Influence of drug therapy.

  1988cites this paper
• Diagnostic heterogeneity in clinical trials for congestive heart failure.

  1988cites this paper
• Relative efficacy of vasodilator therapy in chronic congestive heart failure. Implications of randomized trials.

  1988cites this paper
• Measurement of the quality of life in congestive heart failure—Influence of drug therapy

  1988cites this paper
• Self-assessed disability in patients with arthrosis of the hip joint. Reliability of the Swedish version of the Nottingham Health Profile.

  1988cites this paper
• Measurement of the quality of life in angina.

  1987cites this paper
• Day hospitals' cost and effectiveness: a summary.

  1987cites this paper
• Recruitment experience in clinical trials: literature summary and annotated bibliography.

  1987cites this paper
• Problems in New‐Drug Development: Therapeutic Agents for Ventricular Arrhythmias

  1986cites this paper
• The Treatment of Heart Failure

  1986cites this paper
• Determining optimal therapy--randomized trials in individual patients.

  1986cites this paper