{"corpus_id":1276130,"paper_sha":"5152ce7a47b9058fe6efe28127db2f19a5849caf","doi":"10.1038/bjc.1991.14","arxiv_id":null,"pmid":1846553,"pmcid":"1971664","mag_id":2074122881,"dblp_id":null,"acl_id":null,"title":"Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor alpha and insulin like growth factor-I.","year":1991,"publication_date":"1991-01-01","venue":"British Journal of Cancer","journal":{"name":"British Journal of Cancer","pages":"67 - 70","volume":"63"},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle"],"pubmed_pub_types":["Journal Article"],"s2_fields_of_study":["Biology","Medicine"],"reference_count":28,"citation_count":65,"influential_citation_count":3,"is_open_access":true,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":[{"d":"Cell Division","mj":false,"qs":[{"q":"drug effects","mj":false,"ui":"Q000187"}],"ui":"D002455"},{"d":"Colonic Neoplasms","mj":false,"qs":[{"q":"drug therapy","mj":false,"ui":"Q000188"},{"q":"pathology","mj":true,"ui":"Q000473"},{"q":"ultrastructure","mj":false,"ui":"Q000648"}],"ui":"D003110"},{"d":"Drug Synergism","mj":false,"ui":"D004357"},{"d":"Drug Therapy, Combination","mj":false,"ui":"D004359"},{"d":"ErbB Receptors","mj":false,"qs":[{"q":"physiology","mj":false,"ui":"Q000502"}],"ui":"D066246"},{"d":"Gastrins","mj":false,"qs":[{"q":"pharmacology","mj":true,"ui":"Q000494"}],"ui":"D005755"},{"d":"Humans","mj":false,"ui":"D006801"},{"d":"Insulin-Like Growth Factor I","mj":false,"qs":[{"q":"pharmacology","mj":true,"ui":"Q000494"}],"ui":"D007334"},{"d":"Mitogens","mj":false,"qs":[{"q":"pharmacology","mj":false,"ui":"Q000494"}],"ui":"D008934"},{"d":"Receptors, Cell Surface","mj":false,"qs":[{"q":"physiology","mj":false,"ui":"Q000502"}],"ui":"D011956"},{"d":"Receptors, Somatomedin","mj":false,"ui":"D017451"},{"d":"Stomach Neoplasms","mj":false,"qs":[{"q":"drug therapy","mj":false,"ui":"Q000188"},{"q":"pathology","mj":true,"ui":"Q000473"},{"q":"ultrastructure","mj":false,"ui":"Q000648"}],"ui":"D013274"},{"d":"Transforming Growth Factor alpha","mj":false,"qs":[{"q":"pharmacology","mj":true,"ui":"Q000494"}],"ui":"D016211"},{"d":"Tumor Cells, Cultured","mj":false,"ui":"D014407"}],"chemicals":[{"n":"Gastrins","ui":"D005755","reg":"0"},{"n":"Mitogens","ui":"D008934","reg":"0"},{"n":"Receptors, Cell Surface","ui":"D011956","reg":"0"},{"n":"Receptors, Somatomedin","ui":"D017451","reg":"0"},{"n":"Transforming Growth Factor alpha","ui":"D016211","reg":"0"},{"n":"Insulin-Like Growth Factor I","ui":"D007334","reg":"67763-96-6"},{"n":"ErbB Receptors","ui":"D066246","reg":"EC 2.7.10.1"}],"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":"https://europepmc.org/articles/pmc1971664?pdf=render","s2_open_access_landing_url":"https://www.semanticscholar.org/paper/5152ce7a47b9058fe6efe28127db2f19a5849caf","s2_open_access_license":"CCBY","s2_open_access_status":"GREEN","pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Epidermal growth factor receptors and insulin like growth factor-I receptors were co-expressed on two gastric and three colorectal tumour cell lines. 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