{"corpus_id":15733484,"paper_sha":"86c35bd11c48cd435f6143f9740d26d8e7a40ab5","doi":null,"arxiv_id":null,"pmid":21526072,"pmcid":"3082802","mag_id":2259722601,"dblp_id":null,"acl_id":null,"title":"The assessment value of transcranial Doppler sonography versus magnetic resonance angiography in vertebrobasilar stroke","year":2010,"publication_date":"2010-02-22","venue":"Journal of Research in Medical Sciences","journal":{"name":"Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences","pages":"133 - 139","volume":"15"},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle"],"pubmed_pub_types":["Journal Article"],"s2_fields_of_study":["Medicine"],"reference_count":20,"citation_count":13,"influential_citation_count":0,"is_open_access":false,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":null,"chemicals":null,"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":null,"s2_open_access_landing_url":null,"s2_open_access_license":null,"s2_open_access_status":null,"pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"BACKGROUND: The goal of this study was to determine the reliability of TCD in evaluation of vertebrobasilar arteries in comparison with brain MRA in patients suffering from acute vertebrobasilar stroke. METHODS: Samples were patients with definite clinical diagnosis of vertebrobasilar stroke. For all patients brain MRI, MRA and TCD were performed during the first 48 hours of admission. Basilar artery was insonated at the depth of 75 to 85 mm and vertebral arteries were insonated at the depth of 45 to 55 mm. On brain MRA, the degree of stenosis in vertebrobasilar arteries was graded from I (normal) to IV (total stenosis) and the correlation between the grade of stenosis and TCD indices were studied. RESULTS: Spearman correlation test revealed a significant correlation between mean flow velocity (MFV) and MRA grading (correlation coefficient = -0.486) as well as end diastolic velocity (EDV) and MRA grading (correlation coefficient = -0.323) with no significant correlation between pulsatility index, peak systolic velocity and MRA grading (p > 0.05). One way ANOVA analysis showed that there was only significant mean MFV and mean EDV difference between grade 1 and other grades. CONCLUSIONS: TCD was only able to differentiate between stenotic and normal pattern and could not assist in the grading of stenosis. On the other hand, in acute vertebrobasilar stroke that TCD performed blindly without visualization of arteries and in a fixed depth it might have limited value in the grading of vertebrobasilar system stenosis.","claims":[{"public_id":"cl_c237d38c738a5d7b4a258add74d0cf0b","status":"active","text":"One-way ANOVA showed significant differences in mean MFV and mean EDV only between grade 1 (normal) and the other stenosis grades, with no significant differences among stenotic grades.","confidence":0.92,"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_c237d38c738a5d7b4a258add74d0cf0b"},{"public_id":"cl_51f493247d6e7e330c1728364bdf6b70","status":"active","text":"Spearman correlation revealed significant correlations between mean flow velocity and MRA stenosis grading (r = -0.486) and between end diastolic velocity and MRA stenosis grading (r = -0.323), while pulsatility index and peak systolic velocity showed no significant correlation with MRA stenosis grading.","confidence":0.95,"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_51f493247d6e7e330c1728364bdf6b70"},{"public_id":"cl_efc250d1dc4841127995075218918bfa","status":"active","text":"TCD performed blindly without arterial visualization at a fixed insonation depth in acute vertebrobasilar stroke has limited value in grading vertebrobasilar system stenosis.","confidence":0.88,"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_efc250d1dc4841127995075218918bfa"},{"public_id":"cl_4882505fc0eae501458790d8b5fe0f46","status":"active","text":"TCD was only able to differentiate between stenotic and normal vascular patterns and could not assist in grading the degree of stenosis in vertebrobasilar arteries.","confidence":0.93,"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_4882505fc0eae501458790d8b5fe0f46"}],"concepts":[{"public_id":"co_25ff65bb6d6571888cad318efe183767","status":"active","name":"acute vertebrobasilar stroke","description":"An ischemic stroke in the vertebrobasilar territory studied here within the first 48 hours of hospital admission.","types":["condition"],"aliases":["vertebrobasilar stroke"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_25ff65bb6d6571888cad318efe183767"},{"public_id":"co_2deb0fc924810979ceed438fb457c42e","status":"active","name":"end diastolic velocity","description":"A TCD-derived measure of blood flow velocity at end-diastole, which showed a significant inverse correlation with MRA stenosis grading in this study.","types":["measurement"],"aliases":["EDV"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_2deb0fc924810979ceed438fb457c42e"},{"public_id":"co_36b2e78ca835e33e7872c5830d60981a","status":"active","name":"peak systolic velocity","description":"A TCD-derived measure of maximum blood flow velocity during systole, found here to have no significant correlation with MRA stenosis grading.","types":["measurement"],"aliases":[],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_36b2e78ca835e33e7872c5830d60981a"},{"public_id":"co_46744060fdc2ff4a3edb53dcc9f6aec1","status":"active","name":"pulsatility index","description":"A TCD parameter reflecting downstream arterial resistance, found here to have no significant correlation with MRA stenosis grading.","types":["measurement"],"aliases":[],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_46744060fdc2ff4a3edb53dcc9f6aec1"},{"public_id":"co_4989fc65870beff6ed4204c61d65031b","status":"active","name":"mean flow velocity","description":"A TCD-derived measure of average blood flow speed in an insonated artery, which showed a significant inverse correlation with MRA stenosis grading in this study.","types":["measurement"],"aliases":["MFV"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_4989fc65870beff6ed4204c61d65031b"},{"public_id":"co_5197a87f5460e1fd87a82a8c3720da40","status":"active","name":"Spearman correlation test","description":"A non-parametric statistical test used here to assess the relationship between TCD flow indices and MRA stenosis grades.","types":["statistical method"],"aliases":["Spearman correlation"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_5197a87f5460e1fd87a82a8c3720da40"},{"public_id":"co_96f6435161cf8933210fd1cead9536cf","status":"active","name":"vertebrobasilar arteries","description":"The posterior circulation vessels including the basilar artery and vertebral arteries evaluated here for stenosis using TCD and MRA.","types":["anatomical structure"],"aliases":[],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_96f6435161cf8933210fd1cead9536cf"},{"public_id":"co_da0ec92fe8f2f12da1c933d72e7d9a47","status":"active","name":"magnetic resonance angiography","description":"A non-invasive imaging modality used here as the reference standard for grading stenosis severity in vertebrobasilar arteries.","types":["diagnostic method"],"aliases":["MRA","brain MRA"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_da0ec92fe8f2f12da1c933d72e7d9a47"},{"public_id":"co_dcb4fcb448b1b6cbb4b49f4b56fe3893","status":"active","name":"one-way ANOVA","description":"A statistical test used here to compare mean TCD indices across the four MRA stenosis grade groups.","types":["statistical method"],"aliases":["one way ANOVA"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_dcb4fcb448b1b6cbb4b49f4b56fe3893"},{"public_id":"co_e1c4c017884670775b39a65aaa77cfe8","status":"active","name":"transcranial Doppler sonography","description":"An ultrasound technique used here to evaluate blood flow velocities in vertebrobasilar arteries in stroke patients by insonating at fixed depths.","types":["diagnostic method"],"aliases":["TCD"],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_e1c4c017884670775b39a65aaa77cfe8"},{"public_id":"co_f87cd3460ae96ce0f4de5c897ce2d022","status":"active","name":"MRA stenosis grading","description":"A four-level scale from grade I (normal) to grade IV (total stenosis) used here to classify vertebrobasilar artery stenosis severity on MRA.","types":["classification system"],"aliases":[],"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["review"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/concepts/co_f87cd3460ae96ce0f4de5c897ce2d022"}],"external_ids":{"DOI":null,"ArXiv":null,"PubMed":21526072,"PubMedCentral":"3082802","MAG":2259722601,"DBLP":null,"ACL":null},"open_access":{"is_open_access":false,"pdf_url":null,"landing_url":"https://sah.borca.ai/papers/15733484","source":null,"pdf_url_source":null,"license":null,"reason":"pdf_url_not_indexed"},"reference_availability":{"status":"available","references_indexed":true,"full_text_available":false,"full_text_source":null,"count_basis":"semantic_scholar_metadata","extraction_status":"not_applicable","reason":null},"source":{"provider":"episteme2","base_corpus":"semantic_scholar_dump","freshness_mode":"unknown","basis":["semantic_scholar_metadata","postgres_metadata"],"limits":["paper metadata is based on indexed upstream scholarly datasets","claims and concepts are available only for extracted papers","absence of claims or concepts means no extracted graph data is available in this response"],"status":"available","degraded":false,"degraded_reasons":[],"diagnostics":{"status":"available","degraded":false,"degraded_reasons":[],"metadata_status":"available","graph_status":"available","abstract_status":"available"},"source_flags":5},"paper_id":637766,"paper_uid":"19823015-a01e-447d-a9b5-8d6e63870b74","canonical_identity":{"paper_id":637766,"paper_uid":"19823015-a01e-447d-a9b5-8d6e63870b74","identity_status":"available","lookup_basis":"semantic_scholar_external_id","compatibility_path":"corpus_id"},"url":"https://sah.borca.ai/papers/15733484"}