{"corpus_id":17141936,"paper_sha":"87fcbb8a85a5574aac295b96b8e3eea3e9b5a79c","doi":"10.1371/journal.pone.0135879","arxiv_id":null,"pmid":26313908,"pmcid":"4552093","mag_id":2124023809,"dblp_id":null,"acl_id":null,"title":"Improving Health-Related Quality of Life among People Living with HIV: Results from an Impact Evaluation of a Food Assistance Program in Uganda","year":2015,"publication_date":"2015-08-27","venue":"PLoS ONE","journal":{"name":"PLoS ONE","pages":null,"volume":"10"},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle"],"pubmed_pub_types":["Journal Article","Research Support, Non-U.S. Gov't"],"s2_fields_of_study":["Medicine","Environmental Science"],"reference_count":74,"citation_count":32,"influential_citation_count":2,"is_open_access":true,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":[{"d":"Adult","mj":false,"ui":"D000328"},{"d":"Female","mj":false,"ui":"D005260"},{"d":"Food Assistance","mj":false,"qs":[{"q":"organization & administration","mj":true,"ui":"Q000458"}],"ui":"D063105"},{"d":"Food Supply","mj":false,"qs":[{"q":"methods","mj":true,"ui":"Q000379"},{"q":"standards","mj":true,"ui":"Q000592"}],"ui":"D005523"},{"d":"HIV Infections","mj":false,"qs":[{"q":"complications","mj":false,"ui":"Q000150"},{"q":"psychology","mj":true,"ui":"Q000523"}],"ui":"D015658"},{"d":"HIV-1","mj":false,"qs":[{"q":"physiology","mj":false,"ui":"Q000502"}],"ui":"D015497"},{"d":"Humans","mj":false,"ui":"D006801"},{"d":"Male","mj":false,"ui":"D008297"},{"d":"Malnutrition","mj":false,"qs":[{"q":"etiology","mj":false,"ui":"Q000209"},{"q":"prevention & control","mj":true,"ui":"Q000517"}],"ui":"D044342"},{"d":"Mental Health","mj":false,"ui":"D008603"},{"d":"Prospective Studies","mj":false,"ui":"D011446"},{"d":"Quality of Life","mj":true,"ui":"D011788"}],"chemicals":null,"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135879&type=printable","s2_open_access_landing_url":"https://www.semanticscholar.org/paper/87fcbb8a85a5574aac295b96b8e3eea3e9b5a79c","s2_open_access_license":"CCBY","s2_open_access_status":"GOLD","pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Introduction Widespread food insecurity in Africa continues to compromise an effective response to the AIDS epidemic. Health-related quality of life (HRQoL) is a comprehensive indicator of physical, mental, and social well-being that is associated with food insecurity and increasingly used to assess the well-being of people living with HIV/AIDS (PLHIV). We examined the impact of a food assistance intervention, previously shown to have reduced household food insecurity and improved nutritional status, on HRQoL of PLHIV. Methods We capitalized on an existing intervention targeting antiretroviral therapy (ART)- naïve PLHIV in Uganda, and conducted a prospective impact evaluation including a treatment and a comparison group. Data analyzed included 640 participants from two districts (318 in the intervention district) interviewed in both clinic and household settings at baseline and again approximately one year later. The main outcomes considered were physical and mental health dimensions of HRQoL, and other outcomes included self- and healthcare provider-reported symptoms. We utilized difference-in-difference propensity score matching methodologies to infer causality and examine program impacts. Results Over 12 months, food assistance significantly increased physical health scores (PHS) by 2.85 (P < .01) or approximately 0.35 SD, and reduced substantially the number of self- and healthcare provider-reported HIV-related symptoms by 3.83 and 2.68, respectively (P < .01). There was no significant impact, however, on mental health scores (MHS). Conclusions This study demonstrates the potential importance for HRQoL of including food assistance programming as part of the standard of care for PLHIV in areas of widespread food insecurity.","claims":[{"public_id":"cl_9bb8cbd2c50536ac0ab22d201e5b2e26","status":"active","text":"A prospective impact evaluation using difference-in-difference propensity score matching assessed a food assistance intervention for antiretroviral therapy-naïve people living with HIV in Uganda.","confidence":0.95,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_9bb8cbd2c50536ac0ab22d201e5b2e26"},{"public_id":"cl_e908731d1442d87d07a100aadeb29f11","status":"active","text":"Food assistance had no significant impact on mental health scores.","confidence":0.97,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_e908731d1442d87d07a100aadeb29f11"},{"public_id":"cl_dcd3c1e630750b1648db69c2fb232483","status":"active","text":"Food assistance increased physical health scores by 2.85 points, about 0.35 standard deviations, over 12 months.","confidence":0.98,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_dcd3c1e630750b1648db69c2fb232483"},{"public_id":"cl_abf1e598dc39523b2d3c615d02d8b953","status":"active","text":"Food assistance reduced self-reported HIV-related symptoms by 3.83 and healthcare provider-reported HIV-related symptoms by 2.68.","confidence":0.98,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_abf1e598dc39523b2d3c615d02d8b953"}],"concepts":[{"public_id":"co_066170dabbfacd56beb76d1c060df413","status":"active","name":"antiretroviral therapy-naïve people living with HIV","description":"People living with HIV who had not yet started antiretroviral therapy.","types":["population"],"aliases":["ART-naïve PLHIV"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_066170dabbfacd56beb76d1c060df413"},{"public_id":"co_2dd99094277cd6722dd7c217f56faf47","status":"active","name":"healthcare provider-reported HIV-related symptoms","description":"Symptoms related to HIV recorded by healthcare providers.","types":["outcome"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_2dd99094277cd6722dd7c217f56faf47"},{"public_id":"co_3bb9d54bb5979253183ec7b4e4f6173d","status":"active","name":"difference-in-difference propensity score matching","description":"An analytic approach combining difference-in-difference estimation with propensity score matching to estimate program impacts.","types":["method"],"aliases":["difference-in-difference","propensity score matching"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_3bb9d54bb5979253183ec7b4e4f6173d"},{"public_id":"co_6eaef4144b34902b97b1c44e7b132980","status":"active","name":"food assistance","description":"Provision of food support to participants as an intervention aimed at improving nutrition and well-being.","types":["intervention"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_6eaef4144b34902b97b1c44e7b132980"},{"public_id":"co_7a50537b090a433f4ebf37c3b7110513","status":"active","name":"self-reported HIV-related symptoms","description":"Symptoms related to HIV that participants reported themselves.","types":["outcome"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_7a50537b090a433f4ebf37c3b7110513"},{"public_id":"co_8411c0864d4538c383abbc33f8f1c2d7","status":"active","name":"physical health scores","description":"A health-related quality of life measure capturing participants' physical well-being.","types":["outcome"],"aliases":["PHS"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_8411c0864d4538c383abbc33f8f1c2d7"},{"public_id":"co_91f36381db1a1c402351b7864651ff7a","status":"active","name":"food assistance intervention","description":"The evaluated program that provided food support to antiretroviral therapy-naïve participants in Uganda.","types":["intervention"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_91f36381db1a1c402351b7864651ff7a"},{"public_id":"co_9f89a5c326429ae0fa49b19d7ac4ff00","status":"active","name":"people living with HIV","description":"Individuals living with human immunodeficiency virus infection.","types":["population"],"aliases":["PLHIV"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_9f89a5c326429ae0fa49b19d7ac4ff00"},{"public_id":"co_9fb0b894aeb6d40c1645bb2059486bd0","status":"active","name":"mental health scores","description":"A health-related quality of life measure capturing participants' mental well-being.","types":["outcome"],"aliases":["MHS"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_9fb0b894aeb6d40c1645bb2059486bd0"},{"public_id":"co_db6eb6f5b40a367deee075bf771666a6","status":"active","name":"health-related quality of life","description":"A measure of physical, mental, and social well-being used here to assess participant well-being.","types":["outcome measure"],"aliases":["HRQoL"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_db6eb6f5b40a367deee075bf771666a6"}],"external_ids":{"DOI":"10.1371/journal.pone.0135879","ArXiv":null,"PubMed":26313908,"PubMedCentral":"4552093","MAG":2124023809,"DBLP":null,"ACL":null},"open_access":{"is_open_access":true,"pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135879&type=printable","landing_url":"https://www.semanticscholar.org/paper/87fcbb8a85a5574aac295b96b8e3eea3e9b5a79c","source":"semantic_scholar","pdf_url_source":"semantic_scholar_open_access_pdf","license":"CCBY","status":"GOLD","reason":null},"reference_availability":{"status":"available","references_indexed":true,"full_text_available":false,"full_text_source":null,"count_basis":"semantic_scholar_metadata","extraction_status":"not_applicable","reason":null},"source":{"provider":"episteme2","base_corpus":"semantic_scholar_dump","freshness_mode":"unknown","basis":["semantic_scholar_metadata","postgres_metadata"],"limits":["paper metadata is based on indexed upstream scholarly datasets","claims and concepts are available only for extracted papers","absence of claims or concepts means no extracted graph data is available in this response"],"status":"available","degraded":false,"degraded_reasons":[],"diagnostics":{"status":"available","degraded":false,"degraded_reasons":[],"metadata_status":"available","graph_status":"available","abstract_status":"available"},"source_flags":5},"paper_id":631136,"paper_uid":"0825290b-f5f5-42c6-87ec-c32a1730d3c1","canonical_identity":{"paper_id":631136,"paper_uid":"0825290b-f5f5-42c6-87ec-c32a1730d3c1","identity_status":"available","lookup_basis":"semantic_scholar_external_id","compatibility_path":"corpus_id"},"url":"https://sah.borca.ai/papers/17141936"}