{"corpus_id":209672084,"paper_sha":"633344ba0c05d4ec20dd2ee15a7a454a20bdff84","doi":"10.1111/jocd.13283","arxiv_id":null,"pmid":31898391,"pmcid":null,"mag_id":2998213422,"dblp_id":null,"acl_id":null,"title":"Emotional disorder syndrome after cosmetic facial injection.","year":2020,"publication_date":"2020-01-02","venue":"Journal of Cosmetic Dermatology","journal":{"name":"Journal of cosmetic dermatology","pages":null,"volume":null},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle"],"pubmed_pub_types":["Case Reports","Journal Article"],"s2_fields_of_study":["Medicine"],"reference_count":18,"citation_count":12,"influential_citation_count":2,"is_open_access":false,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":[{"d":"Adult","mj":false,"ui":"D000328"},{"d":"Cosmetic Techniques","mj":true,"ui":"D003357"},{"d":"Face","mj":false,"ui":"D005145"},{"d":"Female","mj":false,"ui":"D005260"},{"d":"Forehead","mj":false,"ui":"D005546"},{"d":"Humans","mj":false,"ui":"D006801"},{"d":"Hyaluronic Acid","mj":false,"qs":[{"q":"adverse effects","mj":false,"ui":"Q000009"}],"ui":"D006820"},{"d":"Injections, Subcutaneous","mj":false,"ui":"D007279"}],"chemicals":[{"n":"Hyaluronic Acid","ui":"D006820","reg":"9004-61-9"}],"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":null,"s2_open_access_landing_url":null,"s2_open_access_license":null,"s2_open_access_status":null,"pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"There are a number of patients who develop severe anxiety or depression after receiving facial cosmetic injections. We presented a 32-year-old woman who developed frequent panic, tension headache, tachycardia, shortness of breath, and sleep disorder for a year after the injection of hyaluronic acid on her forehead and glabella. Brain magnetic resonance imaging (MRI) showed multiple flaky and slightly longer T1, slightly longer T2 signals on the anterior frontal white matter. However, the patient's brain MRI scan 5 months before the injection showed no such performance. The patient was asked to consult the psychiatrist and was diagnosed with anxiety disorder. We name such phenomenon by Emotional disorder syndrome after cosmetic facial injection and assume that there are three major reasons for the emergence of this syndrome. One reason may be that emotional disorder is caused by the mental state of the patient. The second reason to explain the emotional disorder might be the frontal lobe syndrome caused by the frontal embolism during the filler injection. Another reason may be leukoaraiosis, a brain white matter change which may cause depression and anxiety.","claims":[{"public_id":"cl_7e488b3d496c334bce8000315567e153","status":"active","text":"A 32-year-old woman developed panic, tension headache, tachycardia, shortness of breath, and sleep disorder for a year after hyaluronic acid facial injection.","confidence":0.97,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_7e488b3d496c334bce8000315567e153"},{"public_id":"cl_44eec85e6e78e53097e4ea42e0e80981","status":"active","text":"Brain magnetic resonance imaging after the injection showed multiple flaky, slightly longer T1 and slightly longer T2 signals in the anterior frontal white matter, whereas a scan 5 months before the injection showed no such abnormality.","confidence":0.94,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_44eec85e6e78e53097e4ea42e0e80981"},{"public_id":"cl_a836a639d78cfb8e18d9421d7139d97e","status":"active","text":"Psychiatric consultation led to a diagnosis of anxiety disorder.","confidence":0.93,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_a836a639d78cfb8e18d9421d7139d97e"},{"public_id":"cl_1a76814012dc4a9042e2a9d937349956","status":"active","text":"The term emotional disorder syndrome after cosmetic facial injection is proposed for this post-injection symptom pattern, with three suggested contributing explanations: the patient's mental state, frontal lobe syndrome from frontal embolism during filler injection, and leukoaraiosis.","confidence":0.9,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_1a76814012dc4a9042e2a9d937349956"}],"concepts":[{"public_id":"co_0253799578c2f494e8c493eb3ae8d086","status":"active","name":"anxiety disorder","description":"A psychiatric disorder characterized by excessive anxiety.","types":["diagnosis","condition"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_0253799578c2f494e8c493eb3ae8d086"},{"public_id":"co_32ce078f2f9e42218c23064eee67b851","status":"active","name":"emotional disorder syndrome after cosmetic facial injection","description":"A proposed syndrome describing anxiety- or depression-like symptoms occurring after cosmetic injection in the 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