{"corpus_id":2308439,"paper_sha":"e8505f701b7f86e7c5b3e7efb1284035b3b3997c","doi":"10.2147/CLEP.S40245","arxiv_id":null,"pmid":24523597,"pmcid":"3921083","mag_id":2070831548,"dblp_id":null,"acl_id":null,"title":"The epidemiology of irritable bowel syndrome","year":2014,"publication_date":"2014-02-04","venue":"Clinical Epidemiology","journal":{"name":"Clinical Epidemiology","pages":"71 - 80","volume":"6"},"journal_issn":null,"journal_title":null,"publication_types":["Review","JournalArticle"],"pubmed_pub_types":["Journal Article","Review"],"s2_fields_of_study":["Medicine"],"reference_count":127,"citation_count":923,"influential_citation_count":44,"is_open_access":true,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":null,"chemicals":null,"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":"https://www.dovepress.com/getfile.php?fileID=18892","s2_open_access_landing_url":"https://www.semanticscholar.org/paper/e8505f701b7f86e7c5b3e7efb1284035b3b3997c","s2_open_access_license":"CCBYNC","s2_open_access_status":"GOLD","pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the diagnostic criteria employed, IBS affects around 11% of the population globally. Around 30% of people who experience the symptoms of IBS will consult physicians for their IBS symptoms. These people do not have significantly different abdominal symptoms to those who do not consult, but they do have greater levels of anxiety and lower quality of life. Internationally, there is a female predominance in the prevalence of IBS. There is 25% less IBS diagnosed in those over 50 years and there is no association with socioeconomic status. IBS aggregates within families and the genetic and sociological factors potentially underlying this are reviewed. Patients diagnosed with IBS are highly likely to have other functional disease and have more surgery than the general population. There is no evidence that IBS is associated with an increased mortality risk. The epidemiological evidence surrounding these aspects of the natural history is discussed.","claims":[{"public_id":"cl_18f202b8274a23495f6608d84e2867f7","status":"active","text":"Around 30% of people with IBS symptoms consult physicians for those symptoms.","confidence":0.95,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_18f202b8274a23495f6608d84e2867f7"},{"public_id":"cl_5aa220701a5f0590c11900856c8191cd","status":"active","text":"Depending on the diagnostic criteria employed, IBS affects around 11% of the global population.","confidence":0.97,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_5aa220701a5f0590c11900856c8191cd"},{"public_id":"cl_f47ebf76afe5dd3fc3f88751458c09cc","status":"active","text":"IBS aggregates within families, and patients diagnosed with IBS are highly likely to have other functional disease and to undergo more surgery than the general population.","confidence":0.93,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_f47ebf76afe5dd3fc3f88751458c09cc"},{"public_id":"cl_cda1ea4ad47ea7bfe292cad28e20c7ad","status":"active","text":"IBS prevalence shows a female predominance and is about 25% lower in people over 50 years, with no association with socioeconomic status.","confidence":0.95,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_cda1ea4ad47ea7bfe292cad28e20c7ad"},{"public_id":"cl_74f68230fb5ef41dff5cc20d1a5aa692","status":"active","text":"People who consult physicians for IBS symptoms do not have significantly different abdominal symptoms from non-consulters, but they have greater anxiety and lower quality of life.","confidence":0.94,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_74f68230fb5ef41dff5cc20d1a5aa692"},{"public_id":"cl_068d4508f3bc96bc7b7a9fdd93a18b82","status":"active","text":"There is no evidence that IBS is associated with an increased mortality risk.","confidence":0.96,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_068d4508f3bc96bc7b7a9fdd93a18b82"}],"concepts":[{"public_id":"co_04948e422e1f6b93f75979a9c4eef20a","status":"active","name":"surgery","description":"Operative procedures used more frequently among people diagnosed with IBS.","types":["medical procedure"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_04948e422e1f6b93f75979a9c4eef20a"},{"public_id":"co_17683d2f97b4ceeefe542234b6e90320","status":"active","name":"anxiety","description":"Psychological anxiety measured as a correlate of IBS consultation status.","types":["psychological outcome"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_17683d2f97b4ceeefe542234b6e90320"},{"public_id":"co_1b8c0265e60d1eb029ab6d54581cdbb2","status":"active","name":"mortality risk","description":"The risk of death associated with a condition in epidemiologic follow-up.","types":["outcome"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_1b8c0265e60d1eb029ab6d54581cdbb2"},{"public_id":"co_20613d81328fc44229be22a08c1be22b","status":"active","name":"IBS symptoms","description":"The symptom pattern experienced by people with irritable bowel syndrome.","types":["symptom"],"aliases":["symptoms of IBS"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_20613d81328fc44229be22a08c1be22b"},{"public_id":"co_27a86e1496188c21167377d2b3b336b0","status":"active","name":"socioeconomic status","description":"A person's social and economic position used as an epidemiologic correlate.","types":["demographic factor"],"aliases":["SES"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_27a86e1496188c21167377d2b3b336b0"},{"public_id":"co_28353b27b1f2cfe6667631d0ffc4aafd","status":"active","name":"irritable bowel syndrome","description":"A functional bowel disorder diagnosed using clinical criteria.","types":["condition"],"aliases":["IBS"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_28353b27b1f2cfe6667631d0ffc4aafd"},{"public_id":"co_6532db43f7d4a216249396b90285b66a","status":"active","name":"global population","description":"The worldwide population used as the reference for prevalence estimates.","types":["population"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_6532db43f7d4a216249396b90285b66a"},{"public_id":"co_6dbf755e1de2aced899bec8c5351c2bd","status":"active","name":"diagnostic criteria","description":"Clinical rules or standards used to identify IBS in epidemiological studies.","types":["clinical criterion"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_6dbf755e1de2aced899bec8c5351c2bd"},{"public_id":"co_8026987e608610836506163a55d1c857","status":"active","name":"physician consultation","description":"Seeking medical care from physicians for IBS-related symptoms.","types":["healthcare utilization"],"aliases":["consult physicians"],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_8026987e608610836506163a55d1c857"},{"public_id":"co_94b340cb586870d2e4ce0a5c79f2985c","status":"active","name":"familial aggregation","description":"The tendency for IBS to occur more often within families.","types":["epidemiologic pattern"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_94b340cb586870d2e4ce0a5c79f2985c"},{"public_id":"co_d1e902e2675daca268c9cc472995509c","status":"active","name":"abdominal symptoms","description":"Abdominal symptom burden reported in relation to IBS.","types":["symptom"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_d1e902e2675daca268c9cc472995509c"},{"public_id":"co_f3b09d48f44170b84072c599775c31dc","status":"active","name":"female predominance","description":"A higher prevalence of IBS in women than in men.","types":["epidemiologic pattern"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_f3b09d48f44170b84072c599775c31dc"},{"public_id":"co_ff9c9734278cdb2a99d33089756d6ea8","status":"active","name":"functional disease","description":"Other functional disorders occurring alongside IBS in diagnosed patients.","types":["condition"],"aliases":[],"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/concepts/co_ff9c9734278cdb2a99d33089756d6ea8"}],"external_ids":{"DOI":"10.2147/CLEP.S40245","ArXiv":null,"PubMed":24523597,"PubMedCentral":"3921083","MAG":2070831548,"DBLP":null,"ACL":null},"open_access":{"is_open_access":true,"pdf_url":"https://www.dovepress.com/getfile.php?fileID=18892","landing_url":"https://www.semanticscholar.org/paper/e8505f701b7f86e7c5b3e7efb1284035b3b3997c","source":"semantic_scholar","pdf_url_source":"semantic_scholar_open_access_pdf","license":"CCBYNC","status":"GOLD","reason":null},"reference_availability":{"status":"available","references_indexed":true,"full_text_available":false,"full_text_source":null,"count_basis":"semantic_scholar_metadata","extraction_status":"not_applicable","reason":null},"source":{"provider":"episteme2","base_corpus":"semantic_scholar_dump","freshness_mode":"unknown","basis":["semantic_scholar_metadata","postgres_metadata"],"limits":["paper metadata is based on indexed upstream scholarly datasets","claims and concepts are available only for extracted papers","absence of claims or concepts means no extracted graph data is available in this response"],"status":"available","degraded":false,"degraded_reasons":[],"diagnostics":{"status":"available","degraded":false,"degraded_reasons":[],"metadata_status":"available","graph_status":"available","abstract_status":"available"},"source_flags":5},"paper_id":631238,"paper_uid":"e1ffb7ae-530a-4bf7-9787-aeaca6e54f53","canonical_identity":{"paper_id":631238,"paper_uid":"e1ffb7ae-530a-4bf7-9787-aeaca6e54f53","identity_status":"available","lookup_basis":"semantic_scholar_external_id","compatibility_path":"corpus_id"},"url":"https://sah.borca.ai/papers/2308439"}