{"corpus_id":32374584,"paper_sha":"8ed5232fc9e71f3a0bd20ea6cd513ceb7e5f3198","doi":"10.1016/0014-4886(78)90069-9","arxiv_id":null,"pmid":729684,"pmcid":null,"mag_id":1973527018,"dblp_id":null,"acl_id":null,"title":"Effect of chronic protein malnutrition on experimentally induced seizures in the rat.","year":1978,"publication_date":"1978-11-01","venue":"Experimental Neurology","journal":{"name":"Experimental neurology","pages":"\n          475-81\n        ","volume":"62 2"},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle"],"pubmed_pub_types":["Journal Article"],"s2_fields_of_study":["Biology","Medicine","Psychology"],"reference_count":20,"citation_count":27,"influential_citation_count":0,"is_open_access":false,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":[{"d":"Animals","mj":false,"ui":"D000818"},{"d":"Brain","mj":false,"qs":[{"q":"physiopathology","mj":true,"ui":"Q000503"}],"ui":"D001921"},{"d":"Electroshock","mj":false,"ui":"D004597"},{"d":"Female","mj":false,"ui":"D005260"},{"d":"Injections, Intraperitoneal","mj":false,"ui":"D007274"},{"d":"Pentylenetetrazole","mj":false,"qs":[{"q":"administration & dosage","mj":false,"ui":"Q000008"}],"ui":"D010433"},{"d":"Protein Deficiency","mj":false,"qs":[{"q":"physiopathology","mj":true,"ui":"Q000503"}],"ui":"D011488"},{"d":"Rats","mj":false,"ui":"D051381"},{"d":"Seizures","mj":true,"qs":[{"q":"chemically induced","mj":false,"ui":"Q000139"},{"q":"etiology","mj":false,"ui":"Q000209"}],"ui":"D012640"}],"chemicals":[{"n":"Pentylenetetrazole","ui":"D010433","reg":"WM5Z385K7T"}],"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":null,"s2_open_access_landing_url":null,"s2_open_access_license":null,"s2_open_access_status":null,"pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Abstract Rats malnourished at various stages of development by feeding them a low protein diet were tested at adulthood for susceptibility to motor seizures induced by pentylenetetrazol (PTZ), electroconvulsive shock (ECS), or amygdaloid kindling. Compared to control animals, malnourished rats were more sensitive to ECS, less susceptible to kindled motor seizures, and did not differ in sensitivity to PTZ. We conclude that malnutrition during development does not exert a uniform effect on all classes of seizure phenomena.","claims":[{"public_id":"cl_15b91b0dc22a77a758c00b139e128a56","status":"active","text":"Developmental protein malnutrition decreases susceptibility to amygdaloid kindling-induced motor seizures in adulthood.","confidence":0.97,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"url":"https://sah.borca.ai/claims/cl_15b91b0dc22a77a758c00b139e128a56"},{"public_id":"cl_4d90839dca9384503c30f13a56c54c8b","status":"active","text":"Developmental protein malnutrition increases sensitivity to electroconvulsive shock-induced seizures in adulthood.","confidence":0.98,"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous 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