{"corpus_id":43740131,"paper_sha":"9a17509f791708159ca48aeff047170959b44fe7","doi":"10.1006/GYNO.1998.5223","arxiv_id":null,"pmid":10021308,"pmcid":null,"mag_id":2560024267,"dblp_id":null,"acl_id":null,"title":"Mandibular metastasis in a patient with endometrial cancer.","year":1999,"publication_date":"1999-02-01","venue":"Gynecologic Oncology","journal":{"name":"Gynecologic oncology","pages":"\n          243-5\n        ","volume":"72 2"},"journal_issn":null,"journal_title":null,"publication_types":["JournalArticle","CaseReport"],"pubmed_pub_types":["Case Reports","Journal Article"],"s2_fields_of_study":["Medicine"],"reference_count":10,"citation_count":36,"influential_citation_count":0,"is_open_access":false,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":[{"d":"Adenocarcinoma","mj":false,"qs":[{"q":"secondary","mj":true,"ui":"Q000556"},{"q":"therapy","mj":true,"ui":"Q000628"}],"ui":"D000230"},{"d":"Aged","mj":false,"ui":"D000368"},{"d":"Chemotherapy, Adjuvant","mj":false,"ui":"D017024"},{"d":"Endometrial Neoplasms","mj":false,"qs":[{"q":"pathology","mj":true,"ui":"Q000473"},{"q":"therapy","mj":true,"ui":"Q000628"}],"ui":"D016889"},{"d":"Female","mj":false,"ui":"D005260"},{"d":"Humans","mj":false,"ui":"D006801"},{"d":"Hysterectomy","mj":false,"ui":"D007044"},{"d":"Magnetic Resonance Imaging","mj":false,"ui":"D008279"},{"d":"Mandibular Neoplasms","mj":false,"qs":[{"q":"secondary","mj":true,"ui":"Q000556"},{"q":"therapy","mj":true,"ui":"Q000628"}],"ui":"D008339"},{"d":"Radiotherapy, Adjuvant","mj":false,"ui":"D018714"}],"chemicals":null,"comments_corrections":null,"source_flags":5,"s2_open_access_pdf_url":null,"s2_open_access_landing_url":null,"s2_open_access_license":null,"s2_open_access_status":null,"pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Gynecologic cancers metastatic to bone are a rare entity, and a metastasis to the mandible at initial presentation is even more infrequently seen. We present a case of a 71-year-old woman with stage IV endometrial cancer with a metastasis to the mandible, with no other sites of distal spread apparent. The endometrial tumor was a FIGO grade III adenocarcinoma. The pathologic evaluation of the mandibular lesion revealed poorly differentiated adenocarcinoma with focal squamous differentiation. She was treated with a total abdominal hysterectomy and bilateral salpingo-oophorectomy, radiation therapy to the mandible, and chemotherapy consisting of Taxol and carboplatin for six cycles. She had a complete response, but 10 months after the original diagnosis developed spinal cord compression and progressive disease in the pelvis. Patients in good clinical condition with a single bone metastasis should be treated aggressively, as survival can be extended.","claims":[{"public_id":"cl_c51012e9783e8db5f128bc2c77cc94bf","status":"active","text":"Despite the complete response, the patient developed spinal cord compression and progressive disease in the pelvis 10 months after the original diagnosis.","confidence":0.85,"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["review"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_c51012e9783e8db5f128bc2c77cc94bf"},{"public_id":"cl_0783de34c15ef4307149ec9058c47214","status":"active","text":"Patients in good clinical condition with a single bone metastasis should be treated aggressively, as survival can be extended.","confidence":0.75,"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["review"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_0783de34c15ef4307149ec9058c47214"},{"public_id":"cl_eeb46e2033e52618792098a373271238","status":"active","text":"The mandibular lesion in this patient showed poorly differentiated adenocarcinoma with focal squamous differentiation, consistent with metastasis from endometrial cancer without other sites of distal spread.","confidence":0.9,"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["review"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"url":"https://sah.borca.ai/claims/cl_eeb46e2033e52618792098a373271238"},{"public_id":"cl_760fc32ae457a384afb5f418ca9fcfdb","status":"active","text":"Treatment with total abdominal hysterectomy and bilateral salpingo-oophorectomy, radiation therapy to the mandible, and six cycles of Taxol plus carboplatin chemotherapy produced a complete response.","confidence":0.88,"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale 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