{"corpus_id":74636205,"paper_sha":"8ce6cfcc0e6f314b20ede39476120048d845d904","doi":"10.29333/EJGM/82836","arxiv_id":null,"pmid":null,"pmcid":null,"mag_id":2791933583,"dblp_id":null,"acl_id":null,"title":"Can hyperbaric oxygen therapy turn off the angiogenic switch in corneal neovascularization","year":2010,"publication_date":"2010-01-12","venue":"","journal":{"name":"European journal of general medicine","pages":null,"volume":"7"},"journal_issn":null,"journal_title":null,"publication_types":[],"pubmed_pub_types":null,"s2_fields_of_study":["Medicine","Environmental Science"],"reference_count":13,"citation_count":3,"influential_citation_count":0,"is_open_access":true,"arxiv_categories":null,"arxiv_license":null,"arxiv_journal_ref":null,"mesh_headings":null,"chemicals":null,"comments_corrections":null,"source_flags":1,"s2_open_access_pdf_url":"https://www.ejgm.co.uk/download/can-hyperbaric-oxygen-therapy-turnoff-the-angiogenic-switch-in-cornealneovascularization-6760.pdf","s2_open_access_landing_url":"https://www.semanticscholar.org/paper/8ce6cfcc0e6f314b20ede39476120048d845d904","s2_open_access_license":"CCBY","s2_open_access_status":"HYBRID","pmc_open_access_pdf_url":null,"pmc_open_access_landing_url":null,"pmc_open_access_license":null,"pmc_open_access_status":null,"unpaywall_open_access_pdf_url":null,"unpaywall_open_access_landing_url":null,"unpaywall_open_access_license":null,"unpaywall_open_access_status":null,"abstract":"Cornea normally does not have blood vessels. Corneal neovascularization may develop secondary to various inflammatory and infectious disorders. In corneal neovascularization, new blood vessels grow from the limbal vascular plexus into the cornea. Corneal neovascularization reduces visual acuity by disturbing corneal transparency and increases the risk of corneal graft rejection. Corneal avascularity is maintained by the equilibrium between the angiogenic and anti-angiogenic factors. A shift towards angiogenic factors in this equilibrium is called as “angiogenic switch” (1). 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