A. Aguilera

PROFILE

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Aliases
A. Aguilera, Andrés Aguilera, Andrès Aguilera, Andres Aguilera, A Aguilera, Andrés Aguilera
Publication record
280 papers · 21,769 citations · H-index 78

PAPERS

Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast.
20234 citationsauthor #5
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
202326 citationsauthor #12
Actin nucleators safeguard replication forks by limiting nascent strand degradation
20238 citationsauthor #13
Actin nucleators safeguard replication forks by limiting nascent strand degradation
202313 citationsauthor #13
A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability
20225 citationsauthor #6
MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells.
202224 citationsauthor #6
Detection of R-Loops by In Vivo and In Vitro Cytosine Deamination in Saccharomyces cerevisiae.
20221 citationsauthor #2
Genome-Wide Analysis of DNA-RNA Hybrids in Yeast by DRIPc-Seq and DRIP-Seq.
20221 citationsauthor #3
RNase H1 Hybrid-Binding Domain-Based Tools for Cellular Biology Studies of DNA-RNA Hybrids in Mammalian Cells.
20226 citationsauthor #3
ADAR2-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
20211 citationsauthor #14
Heterogeneity of DNA damage incidence and repair in different chromatin contexts.
202113 citationsauthor #3
The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription–replication conflicts
2021121 citationsauthor #4
Actin nucleation safeguards single-stranded DNA and promotes replication fork protection
20210 citationsauthor #10
Analysis of repair of replication-born double-strand breaks by sister chromatid recombination in yeast.
20210 citationsauthor #3
Author response: DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
20210 citationsauthor #5
BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair ‡
202191 citationsauthor #14
DNA-RNA hybrids at DSBs interfere with repair by homologous recombination
202131 citationsauthor #5
Harmful R-loops are prevented via different cell cycle-specific mechanisms
202145 citationsauthor #5
The SWI/SNF complex, transcription-replication conflicts and cancer: a connection with high therapeutic potential
20214 citationsauthor #2
Editor's evaluation: Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae
20210 citationsauthor #1
Corrigendum: UAP56/DDX39B is a major cotranscriptional RNA-DNA helicase that unwinds harmful R loops genome-wide.
20212 citationsauthor #8
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
202148 citationsauthor #14
The role of chromatin at transcription-replication conflicts as a 8 genome safeguard 9 10 11
20210 citationsauthor #2
C. elegans THSC/TREX-2 deficiency causes replication stress and genome instability.
20211 citationsauthor #7
Homologous Recombination: Methods and Protocols
20213 citationsauthor #1
The Sister-Chromatid Exchange Assay in Human Cells.
202118 citationsauthor #2
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells
202111 citationsauthor #10
The SWI / SNF chromatin remodeling complex helps resolve R8 loop-mediated transcription-replication conflicts 9 10 11
20210 citationsauthor #4
The human nucleoporin Tpr protects cells from RNA-mediated replication stress
202133 citationsauthor #20
The role of chromatin at transcription-replication conflicts as a genome safeguard.
202112 citationsauthor #2
R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin
202128 citationsauthor #4
Editor's evaluation: The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions
20210 citationsauthor #1
VID22 counteracts G-quadruplex-induced genome instability
20213 citationsauthor #9
Detection of DNA Double-Strand Breaks by γ-H2AX Immunodetection.
202117 citationsauthor #2
A new interaction between BRCA2 and DDX5 promotes the repair of DNA breaks at transcribed chromatin
20216 citationsauthor #4
Origin matters: spontaneous DNA–RNA hybrids do not form in trans as a source of genome instability
20206 citationsauthor #2
Spontaneous DNA-RNA hybrids: differential impacts throughout the cell cycle
20203 citationsauthor #4
TDP-43 mutations link Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage
202073 citationsauthor #6
Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage
20201 citationsauthor #6
Histone deacetylases facilitate the accurate repair of broken forks
20206 citationsauthor #3
Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner
202020 citationsauthor #4
UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide
2020106 citationsauthor #8
The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops.
202037 citationsauthor #5
A CDK-regulated chromatin segregase promoting chromosome replication
20207 citationsauthor #9
Looping the (R) Loop in DSB Repair via RNA Methylation.
20203 citationsauthor #2
TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage
20201 citationsauthor #5
Homologous recombination and Mus81 promote replication completion in response to replication fork blockage
202026 citationsauthor #4
A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs
201923 citationsauthor #8
A new role of the Mus81 nuclease for replication completion after fork restart
20192 citationsauthor #4
The Nup84 complex coordinates the DNA damage response to warrant genome integrity
201924 citationsauthor #3
Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion
201919 citationsauthor #3
R-Loops as Promoters of Antisense Transcription.
20196 citationsauthor #2
What causes an RNA-DNA hybrid to compromise genome integrity?
201917 citationsauthor #2
R Loops: From Physiological to Pathological Roles.
2019531 citationsauthor #2
Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
201918 citationsauthor #7
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
201951 citationsauthor #26
The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins
201982 citationsauthor #6
Transcription-mediated replication hindrance: a major driver of genome instability
2019182 citationsauthor #2
Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
201833 citationsauthor #6
Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions.
201837 citationsauthor #6
Detection of DNA-RNA Hybrids In Vivo.
201836 citationsauthor #3
Guidelines and recommendations on yeast cell death nomenclature
2018170 citationsauthor #4
Gene gating at nuclear pores prevents the formation of R loops
20182 citationsauthor #3
Coordinated Activity of Y Family TLS Polymerases and EXO1 Protects Non-S Phase Cells from UV-Induced Cytotoxic Lesions.
20186 citationsauthor #6
The interface between transcription and replication
20180 citationsauthor #1
New insights into the mechanisms preventing co-transcriptional accumulation of R-loops
20180 citationsauthor #1
Transcription-replication conflicts: R-loops as obstacles to replication fork progression
20180 citationsauthor #1
The impact on chromatin and DNA damage response in R-loop-mediated genome instability
20180 citationsauthor #1
The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability
201833 citationsauthor #6
Epigenetic features of human telomeres
201882 citationsauthor #5
Yra1-bound RNA–DNA hybrids cause orientation-independent transcription–replication collisions and telomere instability
201862 citationsauthor #8
Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
201874 citationsauthor #3
The Role of Replication-Associated Repair Factors on R-Loops
201738 citationsauthor #3
DNA–RNA hybrids: the risks of DNA breakage during transcription
2017125 citationsauthor #1
Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability
201744 citationsauthor #3
C. elegans THSC complex deficiency leads to replication stress and genome instability
20170 citationsauthor #4
The need to regulate replication fork speed
20174 citationsauthor #2
The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage
201749 citationsauthor #8
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
201719 citationsauthor #8
Exploring transcription-mediated replication stress and RNA-DNA hybrids as targets of anticancer drugs
20170 citationsauthor #1
Human THO–Sin3A interaction reveals new mechanisms to prevent R‐loops that cause genome instability
2017120 citationsauthor #6
Histone Mutants Separate R Loop Formation from Genome Instability Induction.
201790 citationsauthor #6
Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells.
20178 citationsauthor #4
Understanding R loop-mediated genome instability: a new role for histones and chromatin modifications
20170 citationsauthor #9
Correction for Muñoz-Galván et al., “Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange”
20170 citationsauthor #8
Coordination of stress-mediated gene expression and DNA replication by signaling kinases
20170 citationsauthor #4
Correction: The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development
20161 citationsauthor #3
Transcription–replication conflicts: how they occur and how they are resolved
2016340 citationsauthor #2
Transcription as a Threat to Genome Integrity.
2016165 citationsauthor #2
FANCD2 Facilitates Replication through Common Fragile Sites.
2016159 citationsauthor #11
Mapping and characterization of R-loops causing genetic instability in S. cerevisiae
20160 citationsauthor #3
Roles of human POLD1 and POLD3 in genome stability
201657 citationsauthor #4
High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast
20167 citationsauthor #6
Role of chromatin and the DNA damage response in transcription-associated genome instability
20160 citationsauthor #3
Replication stress and cancer
2015895 citationsauthor #3
Polycomb RING1A- and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression
201533 citationsauthor #6
1 Transcription as a Threat to Genome Integrity
20150 citationsauthor #2
R loops: new modulators of genome dynamics and function
2015669 citationsauthor #2
Methods to study transcription-coupled repair in chromatin.
20156 citationsauthor #3
A unified model for the molecular basis of Xeroderma pigmentosum-Cockayne Syndrome
201514 citationsauthor #3

TIMELINE

1976 4 citations

1980 3 citations

1981 18 citations

1982 2 citations

1984 1 citations

1985 51 citations

1986 42 citations

1988 247 citations

1989 139 citations

1990 2 citations

1991 149 citations

1992 6 citations

1993 50 citations

1994 44 citations

1995 185 citations

1996 44 citations

1997 340 citations

1998 352 citations

1999 3 citations

2000 424 citations

2001 302 citations

2002 1,742 citations

2003 1,325 citations

2004 628 citations

2005 739 citations

2006 824 citations

2007 512 citations

2008 1,681 citations

2009 823 citations

2010 221 citations

2011 1,472 citations

2012 1,443 citations

2013 1,005 citations

2014 1,349 citations

2015 2,031 citations

2016 729 citations

2017 497 citations

2018 535 citations

2019 955 citations

2020 289 citations

2021 488 citations

2022 37 citations

2023 51 citations

Unknown 0 citations

A. Aguilera

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