José A López

Dysregulated Autophagy in Platelets from JAK2V617F-Positive Polycythemia Vera and Essential Thrombocythemia Underlies Bioenergetic Failure As a Possible Mechanism for Thrombohemorrhagic Complications
20220 citationsauthor #9
Unfolded Von Willebrand Factor Interacts with Protein S and Limits Its Anticoagulant Activity
20222 citationsauthor #16
Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP
202215 citationsauthor #14
Introduction to a Review Series on Platelets and Cancer.
202117 citationsauthor #1
Arterial Platelet Adhesion in Atherosclerosis‐Prone Arteries of Obese, Insulin‐Resistant Nonhuman Primates
202118 citationsauthor #8
Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contribute to thrombus propagation.
202056 citationsauthor #8
Proteolysis of Von Willebrand Factor Influences Inflammatory Endothelial Activation and Vascular Compliance in Atherosclerosis
202014 citationsauthor #10
Targeted Proteomics Reveals That the Dominant Mechanism of Gpibα Loss during Platelet Storage Depends on Temperature of Storage
20200 citationsauthor #10
Plasma proteomic profile associated with platelet dysfunction after trauma
202011 citationsauthor #11
Remembering Earl W. Davie, PhD (1927-2020)
20200 citationsauthor #1
Human Platelets Stored at Room Temperature Demonstrate Diminished Resistance to Oxidative Stress Compared to Those Stored at 4°C
20201 citationsauthor #9
Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity
202033 citationsauthor #11
ECHOCARDIOGRAPHIC MOLECULAR IMAGING OF THE EFFECT OF ANTI-CYTOKINE THERAPY FOR ATHEROSCLEROSIS.
202011 citationsauthor #10
Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib.
201918 citationsauthor #10
Transforming Endothelium with Platelet‐Rich Plasma in Engineered Microvessels
201914 citationsauthor #8
Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib.
201978 citationsauthor #16
Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress
201948 citationsauthor #8
Von Willebrand Factor Adhesive Activity and ADAMTS13 Protease Activity in HIV-1-Infected Men
201913 citationsauthor #7
Platelets retain inducible alpha granule secretion by P‐selectin expression but exhibit mechanical dysfunction during trauma‐induced coagulopathy
201927 citationsauthor #11
Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline
20181 citationsauthor #11
Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis
20185 citationsauthor #13
Effects of anti‐β2GPI antibodies on VWF release from human umbilical vein endothelial cells and ADAMTS13 activity
201813 citationsauthor #11
Assessment of Novel Antioxidant Therapy in Atherosclerosis by Contrast Ultrasound Molecular Imaging
201812 citationsauthor #7
Introduction to a review series on nontraditional roles for the hemostatic system in the vessel wall.
20180 citationsauthor #1
Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries.
201840 citationsauthor #9
Molecular Imaging of VWF (von Willebrand Factor) and Platelet Adhesion in Postischemic Impaired Microvascular Reflow
201818 citationsauthor #8
Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment
201811 citationsauthor #10
Introduction to a series of reviews on clinical platelet disorders.
20174 citationsauthor #1
Corrigendum: Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
20176 citationsauthor #12
N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.
201755 citationsauthor #11
Effects of Oral N -Acetylcysteine on Oxidative Stress in Patients with Sickle Cell Disease
20174 citationsauthor #25
Identification of extant vertebrate Myxine glutinosa VWF: evolutionary conservation of primary hemostasis.
20179 citationsauthor #9
Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells.
20171,140 citationsauthor #13
LDL and HDL Have Opposing Effects on VWF Self-Association
20175 citationsauthor #5
Specific electrostatic interactions between charged amino acid residues regulate binding of von Willebrand factor to blood platelets
201723 citationsauthor #7
Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor-modified T-cell therapy.
2017960 citationsauthor #8
Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after CD19 CAR-T Cell Immunotherapy
20173 citationsauthor #6
Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα
2017151 citationsauthor #12
miR-155 Modifies Inflammation, Endothelial Activation and Blood-Brain Barrier Dysfunction in Cerebral Malaria
201766 citationsauthor #12
Glycoprotein Ib-IX-V Complex Transmits Cytoskeletal Forces That Enhance Platelet Adhesion.
201650 citationsauthor #7
VWF Cleavage Products Inhibit Shear-Induced Self-Association
20162 citationsauthor #7
High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion.
201677 citationsauthor #12
A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders.
2016173 citationsauthor #47
Potential Mechanisms for Enhanced Activity of Von Willebrand Factor in Patients with Sickle Cell Disease
20164 citationsauthor #9
Pursuing Ultra-Low VWF Adsorption for Blood-Contacting Devices Under Shear
20161 citationsauthor #4
Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury.
201657 citationsauthor #13
A Quantitative Assay of In Vivo Cleavage of Von Willebrand Factor By ADAMTS13 Reveals Excessive Cleavage in Type 2B Von Willebrand Disease and Diminished Cleavage in Thrombotic Thrombocytopenic Purpura
20160 citationsauthor #6
Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial
201629 citationsauthor #11
A Pilot Study of High-Dose N-Acetylcysteine Infusion in Patients with Sickle Cell Disease
20167 citationsauthor #10
Defective Association of the Platelet Glycoprotein Ib–IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma Formation
20167 citationsauthor #7
ADAMTS13 Synergizes with HDL in Preventing Von Willebrand Factor Self-Association Under Shear Stress
20150 citationsauthor #7
Variable content of von Willebrand factor mutant monomer drives the phenotypic variability in a family with von Willebrand disease.
201517 citationsauthor #10
Effect of N-Acetyl-L-Cysteine on Cysteine Redox Status in Patients with Thrombotic Thrombocytopenic Purpura: Protein Disulfide Bound Cysteine As a Biomarker of Oxidative Stress
20152 citationsauthor #7
The Role of Ligand Density in the Binding of Von Willebrand Factor by the Glycoprotein Ib-IX-V Complex in Platelets
20151 citationsauthor #6
The Transmembrane Domains of β and IX Subunits Mediate the Localization of the Platelet Glycoprotein Ib-IX Complex to the Glycosphingolipid-enriched Membrane Domain*
20156 citationsauthor #6
Evaluation of Cell Types and Morphologies in Sickle Cell Disease with an Imaging Flow Cytometer
20152 citationsauthor #7
Flow-driven assembly of VWF fibres and webs in in vitro microvessels
2015126 citationsauthor #3
N-Acetylcysteine Treatment in Two Patients with Relapsed Thrombotic Thrombocytopenic Purpura Increased ADAMTS13 Activity, Free Thiol Concentration in Plasma, and Inhibited Platelet Activation
20152 citationsauthor #10
Pronostic Value of Pretransplant Echocardiography in Allogeneic Hematopoietic Cell Transplantation
20150 citationsauthor #9
The Epidemiology of Transfusion-related Acute Lung Injury Varies According to the Applied Definition of Lung Injury Onset Time.
201511 citationsauthor #6
Molecular Imaging of Platelet–Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis
201558 citationsauthor #9
Microvascular platforms for the study of platelet-vessel wall interactions.
201417 citationsauthor #3
N‐Acetylcysteine: an old drug, a new insight, a potentially effective treatment for thrombotic thrombocytopenic purpura
201414 citationsauthor #2
Hypochlorous Acid Generated by Neutrophils Inactivates ADAMTS13
201457 citationsauthor #4
Quantitative Analysis of Small Molecular Weight Thiols and Disulfides in Blood from a Sickle Cell Disease Patient Infused with N-Acetyl-L-Cysteine
20141 citationsauthor #6
Anti-β2-GPI Antibodies Induce Von Willebrand Factor Release, Modulate Platelet Binding, and Affect VWF Proteolysis
20140 citationsauthor #8
Nanopost arrays reveal platelets use glycoprotein Ib-IX-V complex to squeeze tight onto von willebrand factor
20140 citationsauthor #5
Signal Transducer and Activator of Transcription 3 (STAT3) Regulates Collagen-Induced Platelet Aggregation Independently of Its Transcription Factor Activity
201367 citationsauthor #11
Viper Venom Proteins Modulating Cell Adhesion Identification and Characterization of Endothelial Glycoprotein Ib Using
20131 citationsauthor #4
Signal Transducer and Activator of Transcription 3 (STAT3) Regulates Collagen-Induced Platelet Aggregation Independently of Its Transcription Factor Activity
201367 citationsauthor #12
High Density Lipoprotein and Apolipoprotein A-I Bind Von Willebrand Factor and Prevent Its Self-Association Into Thick Fibers
20132 citationsauthor #5
Oxidation Of Von Willebrand Factor and ADAMTS13 In Patients With Sickle Cell Disease
20134 citationsauthor #5
Platelet Cytoskeletal Force Transmission Through The GPIb-IX-V Complex
20130 citationsauthor #4
Coagulopathy In Trauma Patients Is Accompanied By Oxidation Of a Methionine Residue In The αC Domain Of Fibrinogen and Abnormal Fibrin Polymerization
20130 citationsauthor #4
Nanopost Arrays Indicate that GPIb-VWf Interactions Play a Role in Platelet Contractility Independent of Integrin αIIbβ3
20131 citationsauthor #4
E-beam nanopost arrays reveal that glycoprotein Ib-IV-X complex and von Willebrand factor interactions transmit platelet cytoskeletal forces
20132 citationsauthor #4
The platelet Fc receptor: a new role for an old actor.
201310 citationsauthor #1
Cocaine and Specific Cocaine Metabolites Induce von Willebrand Factor Release From Endothelial Cells in a Tissue-Specific Manner
201326 citationsauthor #5
Antiphospholipid Antibodies Increase Von Willebrand Factor-Platelet String Formation From Human Endothelial Cells Under Physiologic Flow Conditions
201326 citationsauthor #7
Factor XIII: sticking it to platelets.
20137 citationsauthor #2
Neutrophil-Derived Oxidants Induce a Gain-Of-Function Phenotype In GPIbα
20130 citationsauthor #4
Platelet-Leukocyte Conjugation Mediated By GPIbα-αXβ2 (CD11c/CD18) Interaction
20131 citationsauthor #5
Inherited disorders of platelets: membrane glycoprotein disorders.
201316 citationsauthor #2
Thrombotic Thrombocytopenic Purpura and Related Thrombotic Microangiopathies
20135 citationsauthor #1
Reconstitution Of The Microvascular Thrombopoietic Niche Reveals Cross-Talk Between Megakaryocytes and The Microvasculature
20130 citationsauthor #8
Formation of microvascular networks in vitro
2013175 citationsauthor #11
strings by ADAMTS13 under flow conditions Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF
20130 citationsauthor #1
Reversible Association of 14-3-3 with Platelet Glycoprotein Ibα Regulates the Ability of Cells to Adhere, Roll and Spread On VWF
20120 citationsauthor #2
Simultaneous Exposure of Sites in von Willebrand Factor for Glycoprotein Ib Binding and ADAMTS13 Cleavage: Studies With Ristocetin
201229 citationsauthor #4
STAT 3 Regulates Collagen-Induced Platelet Aggregation Independent of its Transcription Factor Activity Running title :
20120 citationsauthor #11
In vitro microvessels for the study of angiogenesis and thrombosis
2012863 citationsauthor #10
Optical Tweezers High-Strength Bonds with the Platelet GP Ib-IX Complex: Studies Using Ultra-Large Multimers of Von Willebrand Factor form Spontaneous
20120 citationsauthor #1
Flow Driven Self-Assembly of Von Willebrand Factor Strands and Cables in Synthetic Blood Vessels
20120 citationsauthor #3
The Characterization of Microparticle Phenotypes in Stored Red Blood Cell Units.
20120 citationsauthor #4
The rate of hemolysis in sickle cell disease correlates with the quantity of active von Willebrand factor in the plasma.
201195 citationsauthor #6
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.
2011228 citationsauthor #8
Cocaine and Certain of Its Long-Acting Metabolites Stimulate Endothelial Cell Von Willebrand Factor Secretion
20112 citationsauthor #4
Platelet Glycoprotein Ibβ/IX Mediates Glycoprotein Ibα Localization to Membrane Lipid Domain Critical for von Willebrand Factor Interaction at High Shear*
201116 citationsauthor #4
Platelet-type von Willebrand disease update: the disease, the molecule and the animal model
201120 citationsauthor #2
in the resting platelet forms disulfide bonds with 2 glycoprotein Ibß subunits α
20110 citationsauthor #6

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