K. Fuxe

PROFILE

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Aliases
Kjell G. Fuxe, K Fuxe, K. Fuxe, Kjell G Fuxe, Kjell Fuxe
Publication record
1,345 papers · 75,672 citations · H-index 124

PAPERS

5HT1AR-FGFR1 Heteroreceptor Complexes Differently Modulate GIRK Currents in the Dorsal Hippocampus and the Dorsal Raphe Serotonin Nucleus of Control Rats and of a Genetic Rat Model of Depression
20239 citationsauthor #7
Decreased medial prefrontal cortex activity related to impaired novel object preference task performance following GALR2 and Y1R agonists intranasal infusion.
202312 citationsauthor #6
GALR2 and Y1R agonists intranasal infusion enhanced adult ventral hippocampal neurogenesis and antidepressant‐like effects involving BDNF actions
202316 citationsauthor #8
Agonistic properties of a series of psychotropic drugs at 5-HT_1A receptors in rat and human brain membranes determined by [^35S]GTPγS binding assay
20231 citationsauthor #8
Increased density and antagonistic allosteric interactions in A2AR-D2R heterocomplexes in extinction from cocaine use, lost in cue induced reinstatement of cocaine seeking.
20223 citationsauthor #8
Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease
20220 citationsauthor #3
The integrative role of G protein-coupled receptor heterocomplexes in Parkinson’s disease
20223 citationsauthor #2
Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and Neuronal Precursor Cells Proliferation in the Dorsal Hippocampus in Rats
202220 citationsauthor #7
The oxytocin receptor represents a key hub in the GPCR heteroreceptor network: potential relevance for brain and behavior
202229 citationsauthor #10
The Combination of Galanin (1–15) and Escitalopram in Rats Suggests a New Strategy for Alcohol Use Disorder Comorbidity with Depression
20225 citationsauthor #7
Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus with Consequent Augmented Spatial Memory
202220 citationsauthor #6
The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson’s Disease
202210 citationsauthor #9
Dysfunctional Heteroreceptor Complexes as Novel Targets for the Treatment of Major Depressive and Anxiety Disorders
202213 citationsauthor #9
Galanin(1-15) Potentiates the Antidepressant-like Effects Induced by Escitalopram in a Rat Model of Depression
202114 citationsauthor #6
Serotonin Heteroreceptor Complexes and Their Integration of Signals in Neurons and Astroglia—Relevance for Mental Diseases
202123 citationsauthor #12
The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons
20210 citationsauthor #11
Correction to: The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons
20210 citationsauthor #11
Editorial: “Purinergic Signaling 2020: The State-of-The-Art Commented by the Members of the Italian Purine Club”
20212 citationsauthor #2
The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders
20218 citationsauthor #15
Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?
20214 citationsauthor #7
Galanin (1-15) Enhances the Behavioral Effects of Fluoxetine in the Olfactory Bulbectomy Rat, Suggesting a New Augmentation Strategy in Depression
202114 citationsauthor #8
Correction to: The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons
20211 citationsauthor #11
The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects
202193 citationsauthor #9
The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons
20214 citationsauthor #11
Study of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity Ligation Assay
20219 citationsauthor #12
Adenosine A2AReceptors in Substance Use Disorders: A Focus on Cocaine
202015 citationsauthor #6
Conventional and novel pharmacological approaches to treat dopamine-related disorders. Focus on Parkinson's disease and schizophrenia.
202020 citationsauthor #6
Amplification of potential thermogenetic mechanisms in cetacean brains compared to artiodactyl brains
202014 citationsauthor #12
Acute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
202010 citationsauthor #9
Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia
202020 citationsauthor #8
Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex.
202022 citationsauthor #10
Galanin and Neuropeptide Y interaction leads to antidepressant effects through hippocampal cell proliferation.
20200 citationsauthor #4
EVIDENCE FOR THE EXISTENCE OF A2AR-TRKB HETERORECEPTOR COMPLEXES IN THE DORSAL HIPPOCAMPUS OF THE RAT BRAIN: POTENTIAL IMPLICATIONS OF A2AR AND TRKB INTERPLAY UPON AGEING.
202015 citationsauthor #8
Existence of FGFR1-5-HT1AR heteroreceptor complexes in hippocampal astrocytes. Putative link to 5-HT and FGF2 modulation of hippocampal gamma oscillations.
202031 citationsauthor #8
Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus
202018 citationsauthor #5
Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
201917 citationsauthor #4
Galanin (1-15)-fluoxetine interaction in the novel object recognition test. Involvement of 5-HT1A receptors in the prefrontal cortex of the rats.
201921 citationsauthor #8
Galanin(1-15) reverses the impaired long-term memory effect of fluoxetine in the novel object recognition test. Role of 5-HT1A receptor in medial prefrontal cortex
20190 citationsauthor #8
Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS
201934 citationsauthor #2
Role of the galanin N-terminal fragment (1-15) in anhedonia: Involvement of the dopaminergic mesolimbic system
201915 citationsauthor #8
Ethanol Intake and A2A Receptor Overexpression.
20193 citationsauthor #10
Potentiation of cannabinoid signaling in microglia by adenosine A2A receptor antagonists
201952 citationsauthor #12
A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration
201910 citationsauthor #7
On Nobel Laureate Arvid Carlsson
20190 citationsauthor #1
Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids
20197 citationsauthor #6
Central administration of galanin N‐terminal fragment 1–15 decreases the voluntary alcohol intake in rats
201913 citationsauthor #9
Effects of galanin n-terminal fragment (1-15) in sac- charin self-administration and sucrose preference test in rats.
20190 citationsauthor #8
Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy?
20190 citationsauthor #2
Understanding receptor heteromerization and its allosteric integration of signals.
20192 citationsauthor #1
The dopaminergic mesolimbic system are involved in the anhedonic-like effects produced by galanin (1-15) in rats.
20190 citationsauthor #8
Attenuation of Oxytocin and Serotonin 2A Receptor Signaling through Novel Heteroreceptor Formation.
201924 citationsauthor #9
Volume Transmission in Transmitter Peptide Costoring Neurons in the Medulla Oblongata
20192 citationsauthor #1
OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes
201911 citationsauthor #7
Differential allosteric modulation within dopamine D2R - neurotensin NTS1R and D2R - serotonin 5-HT2AR receptor complexes gives bias to intracellular calcium signalling
201915 citationsauthor #6
Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson’s disease and its treatment
201934 citationsauthor #2
Improvement on hippocampal neuroproliferation through galanin and neuropeptide y y1 receptor agonist interaction
20190 citationsauthor #4
On the G Protein-Coupled Receptor Neuromodulation of the Claustrum
201911 citationsauthor #2
Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes
201910 citationsauthor #10
Galanin (1-15) enhancement of the behavioral effects of a 5-HT1AR agonist and fluoxetine in the forced swimming test gives a new therapeutic strategy against depression: possible role of GALR1-GALR2-5-HT1AR heteroreceptor complexes
20190 citationsauthor #9
A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction.
201844 citationsauthor #4
Coimmunoprecipitation (co-IP) Analysis for Protein-Protein Interactions in the Neurons of the Cerebral Ganglia of the Land Snails of the Genus Polymita During Aestivation
20180 citationsauthor #3
Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen
20187 citationsauthor #5
Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test
20180 citationsauthor #8
Searching the GPCR Heterodimer Network (GPCR-hetnet) Database for Information to Deduce the Receptor–Receptor Interface and Its Role in the Integration of Receptor Heterodimer Functions
20181 citationsauthor #17
Brain of the tree pangolin (Manis tricuspis). III. The unusual locus coeruleus complex
201811 citationsauthor #5
In Vivo Microdialysis Technique Applications to Understand the Contribution of Receptor–Receptor Interactions to the Central Nervous System Signaling
20180 citationsauthor #5
Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington’s disease
20189 citationsauthor #9
Electrophysiological Approach to GPCR–RTK Interaction Study in Hippocampus of Adult Rats
20184 citationsauthor #8
Isolation and Detection of G Protein-Coupled Receptor (GPCR) Heteroreceptor Complexes in Rat Brain Synaptosomal Preparation Using a Combined Brain Subcellular Fractionation/Co-immunoprecipitation (Co-IP) Procedures
20180 citationsauthor #13
Use of Superfused Synaptosomes to Understand the Role of Receptor–Receptor Interactions as Integrative Mechanisms in Nerve Terminals from Selected Brain Region
20181 citationsauthor #5
Receptor–Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment
201847 citationsauthor #15
Analysis and Quantification of GPCR Heteroreceptor Complexes and Their Allosteric Receptor–Receptor Interactions Using Radioligand Binding Autoradiography
20180 citationsauthor #5
Behavioral Methods to Study the Impact of Receptor–Receptor Interactions in Fear and Anxiety
20180 citationsauthor #5
Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation
201852 citationsauthor #6
Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats
201846 citationsauthor #8
Detection, Analysis, and Quantification of GPCR Homo- and Heteroreceptor Complexes in Specific Neuronal Cell Populations Using the In Situ Proximity Ligation Assay
20185 citationsauthor #26
Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer
201863 citationsauthor #8
Small Interference RNA Knockdown Rats in Behavioral Functions: GALR1/GALR2 Heteroreceptor in Anxiety and Depression-Like Behavior
20186 citationsauthor #5
Glutamate heteroreceptor complexes in the brain
201837 citationsauthor #4
A Novel Integrative Mechanism in Anxiolytic Behavior Induced by Galanin 2/Neuropeptide Y Y1 Receptor Interactions on Medial Paracapsular Intercalated Amygdala in Rats
201821 citationsauthor #11
Co-immunoprecipitation (Co-IP) of G Protein-Coupled Receptor (GPCR)-Receptor Tyrosine Kinase (RTK) Complexes from the Dorsal Hippocampus of the Rat Brain
20181 citationsauthor #7
Adenosine A2A receptor ligand recognition and signaling is blocked by A2B receptors
201878 citationsauthor #11
Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors
201846 citationsauthor #15
Effects of Long‐Term Alcohol Drinking on the Dopamine D2 Receptor: Gene Expression and Heteroreceptor Complexes in the Striatum in Rats
201859 citationsauthor #9
Galanin and neuropeptide y Y1 receptor agonist coinjection increases newborn cells proliferation on hippocampal dentate gyrus in rats
20180 citationsauthor #4
Differential activation of arginine-vasopressin receptor subtypes in the amygdaloid modulation of anxiety in the rat by arginine-vasopressin
201818 citationsauthor #9
Methods to Identify the Signature of Trimers Formed by Three G Protein-Coupled Receptors or by Two G Protein-Coupled and One Ionotropic Receptor with Special Emphasis in the Functional Role in the Central Nervous System
20181 citationsauthor #5
Detection of Fibroblast Growth Factor Receptor 1 (FGFR1) Transactivation by Muscarinic Acetylcholine Receptors (mAChRs) in Primary Neuronal Hippocampal Cultures Through Use of Biochemical and Morphological Approaches
20180 citationsauthor #4
Dopamine D2 Receptor Supersensitivity as a Spectrum of Neurotoxicity and Status in Psychiatric Disorders
201819 citationsauthor #8
Analysis and Quantification of GPCR Allosteric Receptor–Receptor Interactions Using Radioligand Binding Assays: The A2AR-D2R Heteroreceptor Complex Example
20180 citationsauthor #16
Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.
2018110 citationsauthor #13
On the Study of D 4 R-MOR Receptor–Receptor Interaction in the Rat Caudate Putamen: Relevance on Morphine Addiction
20181 citationsauthor #6
The 5-HT1A receptors are involved in the effect of galanin(1-15) on fluoxetine-mediated action in the forced swimming test
20170 citationsauthor #9
GALANIN ( 1-15 ) ENHANCES THE BEHAVIORAL EFFECTS OF FLUOXETINE IN THE FORCED SWIMMING TEST : A NEW THERAPEUTIC STRATEGY AGAINST DEPRESSION
20170 citationsauthor #7
Cocaine modulates allosteric D2-σ1 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum.
201723 citationsauthor #9
IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia
201717 citationsauthor #4
Existence of Brain 5-HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5-HT1A Receptor Recognition
201752 citationsauthor #14
Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease
2017120 citationsauthor #15
Disturbances in the FGFR1-5-HT1A Heteroreceptor Complexes in the Raphe-Hippocampal 5-HT System Develop in a Genetic Rat Model of Depression
201724 citationsauthor #16
Galanin (1–15) enhancement of the behavioral effects of Fluoxetine in the forced swimming test gives a new therapeutic strategy against depression
201739 citationsauthor #8

TIMELINE

1960 5 citations

1962 5 citations

1963 361 citations

1964 7,084 citations

1965 3,374 citations

1966 3,290 citations

1967 1,644 citations

1968 954 citations

1969 1,792 citations

1970 1,656 citations

1971 1,586 citations

1972 1,962 citations

1973 838 citations

1974 2,663 citations

1975 471 citations

1976 934 citations

1977 1,373 citations

1978 817 citations

1979 894 citations

1980 864 citations

1981 639 citations

1982 402 citations

1983 1,746 citations

1984 919 citations

1985 2,057 citations

1986 875 citations

1987 1,084 citations

1988 1,067 citations

1989 602 citations

1990 608 citations

1991 1,068 citations

1992 1,232 citations

1993 1,086 citations

1994 902 citations

1995 1,237 citations

1996 783 citations

1997 1,649 citations

1998 2,544 citations

1999 425 citations

2000 1,197 citations

2001 441 citations

2002 1,435 citations

2003 1,489 citations

2004 890 citations

2005 817 citations

2006 1,380 citations

2007 2,210 citations

2008 1,626 citations

2009 782 citations

2010 2,392 citations

2011 709 citations

2012 1,027 citations

2013 629 citations

2014 1,093 citations

2015 732 citations

2016 918 citations

2017 484 citations

2018 687 citations

2019 281 citations

2020 165 citations

2021 172 citations

2022 103 citations

2023 38 citations

Unknown 26 citations

K. Fuxe

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