K. Hashimoto

PROFILE

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Aliases
K Hashimoto, K. Hashimoto, Kenji Hashimoto, Kijiro Hashimoto
Publication record
703 papers · 38,114 citations · H-index 100

PAPERS

Ketamine and its Metabolites: potential as novel treatments for depression.
20236 citationsauthor #1
Efficacy and safety of perioperative application of ketamine on postoperative depression: A meta-analysis of randomized controlled studies
202340 citationsauthor #5
Risk of esketamine anesthesia on the emergence delirium in preschool children after minor surgery: a prospective observational clinical study
202317 citationsauthor #8
The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling
202319 citationsauthor #13
Arketamine for cognitive impairment in psychiatric disorders
202333 citationsauthor #1
Overview of the potential use of fluvoxamine for COVID-19 and long COVID
202323 citationsauthor #1
Mesenchymal stem-cell-derived microvesicles ameliorate MPTP-induced neurotoxicity in mice: a role of the gut–microbiota–brain axis
20237 citationsauthor #7
Involvement of the agranular insular cortex in antidepressant actions of arketamine
20220 citationsauthor #12
Soluble Epoxide Hydrolase as a Therapeutic Target for Neuropsychiatric Disorders
202230 citationsauthor #2
Repeated intermittent administration of (R)-ketamine during juvenile and adolescent stages prevents schizophrenia-relevant phenotypes in adult offspring after maternal immune activation: a role of TrkB signaling
202221 citationsauthor #7
Effect of Intraoperative Esketamine Infusion on Postoperative Sleep Disturbance After Gynecological Laparoscopy
2022139 citationsauthor #6
Mental health during the COVID-19 pandemic, impact of childhood trauma in psychiatric disorders, and predictable biomarkers for bipolar disorder
20221 citationsauthor #1
Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine
202248 citationsauthor #11
The Toll-like receptor 4 antagonist TAK-242 induces antidepressant-like effects in a rat learned helplessness model of depression through BDNF-TrkB signaling and AMPA receptor activation.
202213 citationsauthor #5
Ketamine and its metabolites: Potential as novel treatments for depression.
202255 citationsauthor #3
Comments to behavioral tests for antidepressant-like actions of (2R,6R)–hydroxynorketamine by Bonaventura et al.
20226 citationsauthor #2
A Bibliometric Analysis of Research on the Role of BDNF in Depression and Treatment
202221 citationsauthor #8
Mechanisms of action of fluvoxamine for COVID-19: a historical review
2022107 citationsauthor #3
Do you know the novel antidepressant arketamine?
20220 citationsauthor #1
Comments to “Fluvoxamine and long COVID-19: a new role for sigma-1 receptor (S1R) agonists” by Khani and Entezari-Maleki
20227 citationsauthor #3
A role of GABAA receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
202216 citationsauthor #9
Deleterious effects of nervous system in the offspring following maternal SARS-CoV-2 infection during the COVID-19 pandemic
202216 citationsauthor #4
Ketamine: anesthetic, psychotomimetic, antidepressant, or anthelmintic?
202230 citationsauthor #1
Effects of splenectomy on skin inflammation and psoriasis-like phenotype of imiquimod-treated mice
202237 citationsauthor #10
Ifenprodil tartrate treatment of adolescents with post-traumatic stress disorder: A double-blind, placebo-controlled trial.
202210 citationsauthor #2
Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation
202235 citationsauthor #8
Gut–microbiota–brain axis by bile acids in depression
202224 citationsauthor #1
Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity
202231 citationsauthor #9
Effects of Subdiaphragmatic Vagotomy in the MPTP-induced Neurotoxicity in the Striatum and Colon of Mice
20225 citationsauthor #5
(R)-ketamine as prophylactic and therapeutic drug for neurological disorders: beyond depression.
202247 citationsauthor #3
EditorialSpecial issue on "Brain-body communication in health and diseases".
20224 citationsauthor #1
Arketamine, a new rapid-acting antidepressant: A historical review and future directions.
202278 citationsauthor #3
Sex-Specific Differences in the Transcriptome of the Human Dorsolateral Prefrontal Cortex in Schizophrenia
202211 citationsauthor #13
The role of hippocampal KCNQ2 channel in antidepressant actions of ketamine.
202221 citationsauthor #2
Reduction of dopamine and glycogen synthase kinase-3 signaling in rat striatum after repeated administration of haloperidol.
20214 citationsauthor #9
Neural rhythm in the retrosplenial cortex during ketamine-induced dissociation
20215 citationsauthor #1
No changes of expression of GPR56 protein in the parietal cortex, cerebellum, and liver from psychiatric disorders
20210 citationsauthor #2
Linking 5-hydroxytryptamine to antidepressant actions of (R)-ketamine and social stress model
20210 citationsauthor #2
A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.
2021141 citationsauthor #8
Regulation of neurotoxicity in the striatum and colon of MPTP-induced Parkinson's disease mice by gut microbiome.
202120 citationsauthor #7
(R)-Ketamine attenuates LPS-induced endotoxin-derived delirium through inhibition of neuroinflammation
202160 citationsauthor #6
Loss of parvalbumin-positive cells in mouse brain regions after repeated intermittent administration of esketamine, but not R-ketamine.
20210 citationsauthor #5
Less Social Support for Patients With COVID-19: Comparison With the Experience of Nurses
202122 citationsauthor #16
Abnormal gene expression of BDNF, but not BDNF-AS, in iPSC, neural stem cells and postmortem brain samples from bipolar disorder.
20216 citationsauthor #8
Abnormalities of the composition of the gut microbiota and short-chain fatty acids in mice after splenectomy
202133 citationsauthor #8
Serum levels of glial cell line-derived neurotrophic factor as a biomarker for mood disorders and lithium response.
202111 citationsauthor #22
Effects of repeated electroconvulsive shocks on dopamine supersensitivity psychosis model rats.
20216 citationsauthor #9
Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor
2021206 citationsauthor #3
Upregulation of heat-shock protein HSP-70 and glutamate transporter-1/glutamine synthetase in the striatum and hippocampus in haloperidol-induced dopamine-supersensitivity-state rats.
20217 citationsauthor #9
Microglial depletion and abnormalities in gut microbiota composition and short-chain fatty acids in mice after repeated administration of colony stimulating factor 1 receptor inhibitor PLX5622
202129 citationsauthor #8
Reviews of "Inhibition of SARS-CoV-2 infection in human cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoskeleton architecture and contractility"
20210 citationsauthor #2
Old drug fluvoxamine, new hope for COVID-19
202127 citationsauthor #3
(R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture.
202124 citationsauthor #7
(R)-ketamine ameliorates the progression of experimental autoimmune encephalomyelitis in mice.
202124 citationsauthor #6
Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure
202119 citationsauthor #6
Correction: Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
20218 citationsauthor #8
Intranasal administration of transforming growth factor-β1 elicits rapid-acting antidepressant-like effects in a chronic social defeat stress model: A role of TrkB signaling.
202126 citationsauthor #3
Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents
202186 citationsauthor #8
Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice
202134 citationsauthor #8
Dextran sulfate sodium-induced inflammation and colitis in mice are ameliorated by (R)-ketamine, but not (S)-ketamine: A role of TrkB signaling.
202121 citationsauthor #5
Repurposing of CNS drugs to treat COVID-19 infection: targeting the sigma-1 receptor
2021101 citationsauthor #1
Abnormalities in the composition of the gut microbiota in mice after repeated administration of DREADD ligands.
20217 citationsauthor #5
Antidepressant-like actions of the mGlu2/3 receptor antagonist TP0178894 in the chronic social defeat stress model: Comparison with escitalopram.
202114 citationsauthor #7
Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine
2021175 citationsauthor #8
Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve.
202195 citationsauthor #15
Relationship between perception and anxiety about COVID-19 infection and risk behaviors for spreading infection: A national survey in Japan
202084 citationsauthor #10
Molecular mechanisms of the rapid-acting and long-lasting antidepressant actions of (R)-ketamine.
2020184 citationsauthor #1
Perception of and anxiety about COVID-19 infection and risk behaviors for spreading infection: an international comparison
202027 citationsauthor #10
Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study
202087 citationsauthor #10
Knowledge and attitudes of medical staff in Chinese psychiatric hospitals regarding COVID-19
2020297 citationsauthor #6
Reply to Reeves and Dunn: Risk for autism in offspring after maternal glyphosate exposure
20202 citationsauthor #1
Antidepressant Actions of Ketamine and Its Two Enantiomers
20201 citationsauthor #3
Antipsychotic-like effects of a novel phosphodiesterase 10A inhibitor MT-3014 in rats.
20207 citationsauthor #9
Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder.
202019 citationsauthor #23
Dietary intake of glucoraphanin during pregnancy and lactation prevents the behavioral abnormalities in the offspring after maternal immune activation
202029 citationsauthor #7
Differential effects of ketamine metabolites on depression-like behaviors induced by chronic corticosterone injection in mice
20200 citationsauthor #9
A historical review of antidepressant effects of ketamine and its enantiomers.
2020133 citationsauthor #3
Abnormal expression of colony stimulating factor 1 receptor (CSF1R) and transcription factor PU.1 (SPI1) in the spleen from patients with major psychiatric disorders: A role of brain-spleen axis.
202030 citationsauthor #4
Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?
202019 citationsauthor #1
(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression.
202052 citationsauthor #12
Betaine supplementation is associated with the resilience in mice after chronic social defeat stress: a role of brain-gut-microbiota axis.
202044 citationsauthor #11
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase
2020133 citationsauthor #16
Pharmacological inhibition of soluble epoxide hydrolase alleviates chronic neuropathic pain induced anhedonia symptoms: differential role of AhR and TSPO signaling
20200 citationsauthor #6
Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control
20201,003 citationsauthor #19
Antibiotic-induced microbiome depletion is associated with resilience in mice after chronic social defeat stress.
202076 citationsauthor #6
Current status of potential therapeutic candidates for the COVID-19 crisis
2020255 citationsauthor #3
Plasma levels of matrix metalloproteinase‐9 (MMP‐9) are associated with cognitive performance in patients with schizophrenia
202020 citationsauthor #15
Risk of neuropsychiatric disorders in offspring of COVID-19-infected pregnant women and nutritional intervention
202012 citationsauthor #1
Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve
2020149 citationsauthor #10
Brain-derived neurotrophic factor-TrkB signaling and the mechanism of antidepressant activity by ketamine in mood disorders
20209 citationsauthor #1
Glyphosate exposure exacerbates the dopaminergic neurotoxicity in the mouse brain after repeated administration of MPTP.
202017 citationsauthor #8
Impact of age on optimal dose of antidepressants
20204 citationsauthor #1
Corrigendum to "Prophylactic Effects of Sulforaphane on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation" Journal of Nutritional Biochemistry 39 (2017) 134-144.
20202 citationsauthor #11
Ketamine: From Abused Drug to Rapid-Acting Antidepressant
20206 citationsauthor #1
Efficacy of anticonvulsant ethosuximide for major depressive disorder: a randomized, placebo-control clinical trial
20208 citationsauthor #11
Treatment concerns for psychiatric symptoms in patients with COVID-19 with or without psychiatric disorders
202042 citationsauthor #4
Corrigendum to "Prophylactic Effects of Sulforaphane on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation" [Journal of Nutritional Biochemistry; 39(2017); 134-144].
20200 citationsauthor #11
Association between serum levels of glial cell line-derived neurotrophic factor and inattention in adult patients with attention deficits/hyperactivity disorder.
20205 citationsauthor #8
Essential role of microglial transforming growth factor-β1 in antidepressant actions of (R)-ketamine and the novel antidepressant TGF-β1
2020107 citationsauthor #16
Neuronal brain injury after cerebral ischemic stroke is ameliorated after subsequent administration of (R)-ketamine, but not (S)-ketamine.
202032 citationsauthor #9

TIMELINE

1976 0 citations

1988 0 citations

1992 1 citations

1993 1 citations

1995 89 citations

1996 98 citations

1997 50 citations

1998 109 citations

1999 13 citations

2000 46 citations

2001 80 citations

2002 270 citations

2003 2,099 citations

2004 1,611 citations

2005 1,404 citations

2006 1,610 citations

2007 2,067 citations

2008 1,719 citations

2009 1,321 citations

2010 1,899 citations

2011 1,423 citations

2012 1,203 citations

2013 1,651 citations

2014 1,295 citations

2015 2,833 citations

2016 2,781 citations

2017 1,927 citations

2018 1,364 citations

2019 1,941 citations

2020 5,082 citations

2021 1,211 citations

2022 813 citations

2023 145 citations

Unknown 0 citations

K. Hashimoto

PROFILE

PAPERS

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