M. Topf

Structural journey of an insecticidal protein against western corn rootworm
20235 citationsauthor #23
Protein target highlights in CASP15: Analysis of models by structure providers
202318 citationsauthor #49
ChemEM: flexible docking of small molecules in Cryo-EM structures using difference maps
20230 citationsauthor #3
Assessment of three-dimensional RNA structure prediction in CASP15
202367 citationsauthor #9
CASP15 cryoEM protein and RNA targets: refinement and analysis using experimental maps
20232 citationsauthor #8
PICKLUSTER: a protein-interface clustering and analysis plug-in for UCSF ChimeraX
202312 citationsauthor #4
New prediction categories in CASP15
202349 citationsauthor #14
Loss-of-Function Variants in DRD1 in Infantile Parkinsonism-Dystonia
20236 citationsauthor #14
Cryo-EM structure and B-factor refinement with ensemble representation
202220 citationsauthor #3
Structural journey of an insecticidal pore-forming protein targeting western corn rootworm
20220 citationsauthor #23
Stoichiometry-Selective Antagonism of α4β2 Nicotinic Acetylcholine Receptors by Fluoroquinolone Antibiotics
20226 citationsauthor #3
Structural mass spectrometry decodes domain interaction and dynamics of the full-length Human Histone Deacetylase 2
20224 citationsauthor #8
MED27, SLC6A7, and MPPE1 Variants in a Complex Neurodevelopmental Disorder with Severe Dystonia
202211 citationsauthor #15
Integrating model simulation tools and cryo‐electron microscopy
202211 citationsauthor #6
GOAT: Deep learning-enhanced Generalized Organoid Annotation Tool
20223 citationsauthor #31
PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma
20223 citationsauthor #29
Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule.
20210 citationsauthor #5
Critical assessment of methods of protein structure prediction (CASP)—Round XIV
2021416 citationsauthor #3
Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule.
20210 citationsauthor #5
Author response for "Cryo‐EM targets in CASP14"
20210 citationsauthor #3
The pore conformation of lymphocyte perforin
202135 citationsauthor #4
TEMPy2: a Python library with improved 3D electron microscopy density-fitting and validation workflows
202128 citationsauthor #7
Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy
20217 citationsauthor #5
TopoStats – A program for automated tracing of biomolecules from AFM images
202138 citationsauthor #7
Target highlights in CASP14: Analysis of models by structure providers
202128 citationsauthor #35
Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition
202119 citationsauthor #5
Cryo‐EM targets in CASP14
202111 citationsauthor #3
Molecular mechanism of a parasite kinesin motor and implications for its inhibition
20210 citationsauthor #5
Editorial: Experiments and Simulations: A Pas de Deux to Unravel Biological Function
20210 citationsauthor #1
Automated Modeling and Validation of Protein Complexes in Cryo-EM Maps.
20200 citationsauthor #3
Assessment of protein–protein interfaces in cryo-EM derived assemblies
202029 citationsauthor #4
TopoStats - an automated tracing program for AFM images
20203 citationsauthor #7
Comparing Cryo-EM Reconstructions and Validating Atomic Model Fit Using Difference Maps
202029 citationsauthor #6
Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy
202030 citationsauthor #5
Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1)
20200 citationsauthor #5
Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2)
20200 citationsauthor #5
Pseudoatomic model of the pre-fusion conformation of glycoprotein B of Herpes simplex virus 1
20200 citationsauthor #11
KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation
202088 citationsauthor #108
Human kinesin-5 motor domain in the AMPPNP state bound to microtubules
20200 citationsauthor #5
Author Correction: A structural model for microtubule minus-end recognition and protection by CAMSAP proteins
20200 citationsauthor #12
The prefusion structure of herpes simplex virus glycoprotein B
202069 citationsauthor #11
Tweedy, J. and Escriva, E. and Topf, Maya and Gompels, U. (2017) Analyses of tissue culture adaptation of human Herpesvirus-6A by whole genome deep sequencing redefines the reference sequence and identifies virus entry
20200 citationsauthor #3
Mapping Aldehyde Dehydrogenase 1A1 Activity using an [18F]Substrate‐Based Approach
20195 citationsauthor #8
Target highlights in CASP13: experimental target structures through the eyes of their authors. Proteins: Structure,
20194 citationsauthor #41
The Cryo-EM Structure and Activity of Kinesin-5 from Plasmodium falciparum: Mechanistic Lessons from a Parasite Kinesin
20190 citationsauthor #3
Cryo‐electron microscopy targets in CASP13: Overview and evaluation of results
201919 citationsauthor #7
Conserved Central Intraviral Protein Interactome of the Herpesviridae Family
20197 citationsauthor #3
Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism
201927 citationsauthor #12
Modeling Protein Monomers and Complexes using Restraints from Crosslinking Mass Spectrometry
20190 citationsauthor #1
Target highlights in CASP13: Experimental target structures through the eyes of their authors
201911 citationsauthor #33
Cover Image, Volume 87, Issue 12
20190 citationsauthor #3
BACTERIOPHAGE SPP1 MATURE CAPSID PROTEIN
20190 citationsauthor #5
Farabella, I. and Vasishtan, D. and Joseph, Agnel Praveen and Pandurangan, Arun Prasad and Sahota, Harpal and Topf, Maya (2015) TEMPy: a Python library for assessment of 3D electron microscopy density
20190 citationsauthor #6
Critical assessment of methods of protein structure prediction (CASP)—Round XIII
2019420 citationsauthor #3
Frequency and phenotypic spectrum of KMT2B dystonia in childhood: A single‐center cohort study
201967 citationsauthor #12
Exome sequencing identifies variants in FKBP4 that are associated with recurrent fetal loss in humans.
201913 citationsauthor #4
Protein interactions and consensus clustering analysis uncover insights into herpesvirus virion structure and function relationships
201919 citationsauthor #6
Modelling structures in cryo-EM maps.
201948 citationsauthor #4
BIROn - Birkbeck Institutional Research Online
20190 citationsauthor #4
BACTERIOPHAGE SPP1 PROCAPSID-I PROTEIN
20190 citationsauthor #6
BACTERIOPHAGE SPP1 PROCAPSID-II PROTEIN
20190 citationsauthor #6
Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor
201814 citationsauthor #6
Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model
201840 citationsauthor #4
Closed conformation of the Membrane Attack Complex
20185 citationsauthor #7
Virus entry complex changes during tissue culture adaptation of human herpesvirus-6A identified by whole genome deep sequencing and structural modelling
20180 citationsauthor #3
OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX
20180 citationsauthor #6
CryoEM Models and Associated Data Submitted to the 2015/2016 EMDataBank Model Challenge
20182 citationsauthor #10
Consensus clustering of herpesvirus protein interaction networks provides insights into their evolutionary relationship with bacteriophages
20180 citationsauthor #6
Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties
201872 citationsauthor #3
Structural Model for Preferential Microtubule Minus End Binding by CAMSAP CKK Domains
20181 citationsauthor #11
Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.
201830 citationsauthor #43
Clinical and molecular characterization of KCNT1-related severe early-onset epilepsy
201892 citationsauthor #27
The evolution of CHC22 clathrin influences its role in human glucose metabolism
20180 citationsauthor #12
EVOLUTION OF THE CLTCL1 GENE ENCODING CHC22 CLATHRIN REVEALS SELECTION INFLUENCING CHC22’S ROLE IN HUMAN GLUCOSE METABOLISM
20180 citationsauthor #11
Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
2018232 citationsauthor #43
Resource Modeling Protein Complex es Using Restraints from Crosslinking Mass Spectrometry Graphical
20180 citationsauthor #4
Jwalk and MNXL web server: model validation using restraints from crosslinking mass spectrometry
201834 citationsauthor #3
CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers
2018101 citationsauthor #7
Modeling Protein Complexes Using Restraints from Crosslinking Mass Spectrometry
201856 citationsauthor #4
The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Nav1.7
201748 citationsauthor #10
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
20170 citationsauthor #5
A structural model for microtubule minus-end recognition and protection by CAMSAP proteins
201796 citationsauthor #12
Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx
20170 citationsauthor #9
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state
20170 citationsauthor #4
The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry
201738 citationsauthor #9
Structural basis of human kinesin-8 function and inhibition
201751 citationsauthor #6
Microtubule-bound MKLP2 motor domain in the with no nucleotide
20170 citationsauthor #9
Cryo EM structure of the E. coli disaggregase ClpB (BAP form, DWB mutant), in the ATPgammaS state, bound to the model substrate casein
20170 citationsauthor #4
Molecular basis of human kinesin-8 function and inhibition
20170 citationsauthor #3
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase
2017122 citationsauthor #4
Correction: Corrigendum: Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia
20171 citationsauthor #66
Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease
201713 citationsauthor #10
Improved metrics for comparing structures of macromolecular assemblies determined by 3D electron-microscopy
201751 citationsauthor #4
Integrative modelling of cellular assemblies.
201715 citationsauthor #4
Analyses of Tissue Culture Adaptation of Human Herpesvirus-6A by Whole Genome Deep Sequencing Redefines the Reference Sequence and Identifies Virus Entry Complex Changes
20178 citationsauthor #3
Solution chemical shifts CAMSAP3 CKK domain
20170 citationsauthor #12
Unravelling the Mechanism of Membrane Attack Complex Pore Closure
20170 citationsauthor #5
Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia
2016204 citationsauthor #66
Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B
2016100 citationsauthor #9
Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessment
201692 citationsauthor #7

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