T. Shimada

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Aliases
T Shimada, T. Shimada, Tsutomu Shimada
Publication record
305 papers · 20,791 citations · H-index 71

PAPERS

Oxidation of 3’-methoxyflavone, 4’-methoxyflavone, and 3’,4’-dimethoxyflavone and their derivatives having 5,7-dihydroxyl moieties by human cytochromes P450 1B1 and 2A13
20224 citationsauthor #1
Roles of cytochrome P450 2A6 in the oxidation of flavone, 4′-hydroxyflavone, and 4′-, 3′-, and 2′-methoxyflavones by human liver microsomes
20217 citationsauthor #9
Initial Serum C-reactive Protein Level as a Predictor of Increasing Serum Vancomycin Concentration During Treatment
20214 citationsauthor #5
Effect of NOS Inhibitors and Anticoagulants on Nitric Oxide Production in a Tissue-factor Induced Rat DIC Model
20211 citationsauthor #3
The active ingredients in the anti‐obesity drug bofutsushosan in high‐fat‐diet‐fed obese mice
20203 citationsauthor #5
Preference for O-demethylation reactions in the oxidation of 2′-, 3′-, and 4′-methoxyflavones by human cytochrome P450 enzymes
202011 citationsauthor #11
Risk Factors for Delayed Elimination of Methotrexate in Children, Adolescents and Young Adults With Osteosarcoma
202011 citationsauthor #5
Administration of erlotinib in apple juice overcomes decreased absorption in a rat model of gastric acid suppression.
20202 citationsauthor #1
Comparison of Tolerability Between 2-Weekly and 3-Weekly Docetaxel Regimen in Castration-resistant Prostate Cancer
20207 citationsauthor #8
Examination of Aggregate Formation upon Simultaneous Dissolution of Methacrylic Acid Copolymer LD Enteric Coating Agent, Pharmaceutical Additives, and Zwitterionic Ingredients.
20201 citationsauthor #4
Liquid chromatography-tandem mass spectrometry analysis of oxidation of 2′-, 3′-, 4′- and 6-hydroxyflavanones by human cytochrome P450 enzymes
20204 citationsauthor #1
Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes.
201913 citationsauthor #12
Palonosetron on Days 1 and 5 Versus Granisetron Daily (Days 1-5) in Germ Cell Tumour Therapy
20193 citationsauthor #7
Cytochrome P450 2A6 and other human P450 enzymes in the oxidation of flavone and flavanone
201916 citationsauthor #11
Risk Factors for Peripheral Neuropathy Induced by Albumin-bound Paclitaxel Plus Gemcitabine Therapy in Pancreatic Cancer Patients
20190 citationsauthor #5
Incidence and risk factors of neonatal hypoglycemia after ritodrine therapy in premature labor: a retrospective cohort study
20199 citationsauthor #7
Detailed assessment and risk factor analysis of corticosteroid-induced psychiatric disorders in pediatric, adolescent, and young adult patients undergoing induction or consolidation therapy for hematologic malignancy
20197 citationsauthor #7
Multiday corticosteroids in cancer chemotherapy delay the diagnosis of and antimicrobial administration for febrile neutropenia: a double-center retrospective study
20193 citationsauthor #5
Hatano rats are a suitable metabolic syndrome model for studying feeding behavior, blood pressure levels, and percent body fat
20181 citationsauthor #2
Consideration of post-marketing drug safety assessment in hospitals
20180 citationsauthor #7
Incidence and Risk Factors of Cholinergic Syndromes Induced by FOLFIRINOX in Advanced Pancreatic Adenocarcinoma
20180 citationsauthor #3
Pharmacokinetics of fentanyl after dermal administration to arthritis model rats
20180 citationsauthor #1
Site-specific oxidation of flavanone and flavone by cytochrome P450 2A6 in human liver microsomes
201810 citationsauthor #12
Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies
201823 citationsauthor #13
Risk factors for oxaliplatin-induced vascular pain in patients with colorectal cancer and comparison of the efficacy of preventive methods
20184 citationsauthor #5
Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants
201819 citationsauthor #1
Title Obesity-induced increase of CYP 2 E 1 activity and its effect on dispositionkinetics of chlorzoxazone in Zucker rats
20170 citationsauthor #2
Drug interaction between methotrexate and salazosulfapyridine in Japanese patients with rheumatoid arthritis
20174 citationsauthor #8
Aggregation in a Suspension of Lansoprazole OD Tablets and Levofloxacin Hydrate Tablets in Water
20172 citationsauthor #5
Title Disposition kinetics of taxanes in peritoneal dissemination
20170 citationsauthor #2
Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastine, adriamycin and cisplatin chemotherapy: a retrospective cohort study
20175 citationsauthor #8
Title Site-dependent contributions of P-glycoprotein and CYP 3 A to cyclosporinA absorption , and effect of dexamethasone in small intestine of mice
20170 citationsauthor #1
Multiple Oral Dosing Pharmacokinetics of Standardized Extract of Centella asiatica ECa 233 and Its Inductive Effect on Efflux Transporters in Rats
201713 citationsauthor #3
Title Establishment of glycosaminoglycan assays for mucopolysaccharidoses
20170 citationsauthor #2
Effect of Kaempferia parviflora extract on knee osteoarthritis
201722 citationsauthor #11
Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity
201749 citationsauthor #1
Roles of Human CYP 2 A 6 and Monkey CYP 2 A 24 and 2 A 26 Cytochrome P 450 Enzymes in the Oxidation of 2 , 5 , 2 ́ , 5 ́Tetrachlorobiphenyl ́Tetrachlorobiphenyl ́Tetrachlorobiphenyl
20160 citationsauthor #1
Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
201631 citationsauthor #1
Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.
201624 citationsauthor #1
Structure − Function Studies of Naphthalene , Phenanthrene , Biphenyl , and Their Derivatives in Interaction with and Oxidation by Cytochromes P 450 2 A 13 and 2 A 6
20165 citationsauthor #1
Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13
201619 citationsauthor #1
Gallic Acid, the Active Ingredient of Terminalia bellirica, Enhances Adipocyte Differentiation and Adiponectin Secretion.
201622 citationsauthor #10
Activity of daily living for Morquio A syndrome.
201626 citationsauthor #3
Effect of switching basal insulin regimen to degludec on quality of life in Japanese patients with type 1 and type 2 diabetes mellitus
201510 citationsauthor #7
Non-invasive pulmonary function test on Morquio patients.
201515 citationsauthor #4
Effects of ethyl acetate extract of Kaempferia parviflora on brown adipose tissue
201525 citationsauthor #7
Di-sulfated keratan sulfate as a novel biomarker for mucopolysaccharidosis IVA
201516 citationsauthor #2
PK/PD analysis of biapenem in patients undergoing continuous hemodiafiltration
20155 citationsauthor #5
Chondroitin 6-Sulfate as a Novel Biomarker for Mucopolysaccharidosis IVA and VII.
201542 citationsauthor #1
Enzyme replacement therapy for treating mucopolysaccharidosis type IVA (Morquio A syndrome): effect and limitations
201561 citationsauthor #3
Long-term follow-up of post hematopoietic stem cell transplantation for Hurler syndrome: Clinical, biochemical, and pathological improvements
201521 citationsauthor #4
Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome
201574 citationsauthor #4
Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.
201514 citationsauthor #1
Di-sulfated Keratan Sulfate as a Novel Biomarker for Mucopolysaccharidosis II, IVA, and IVB.
201542 citationsauthor #1
Noninvasive pulmonary function test on Morquio syndrome type A patients
20150 citationsauthor #4
Analysis of C6S/C4S ratio in Morquio syndrome type A patients
20151 citationsauthor #2
Salacia reticulata has therapeutic effects on obesity
201420 citationsauthor #1
Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora.
201464 citationsauthor #2
Assay for Glycosaminoglycans by Tandem Mass Spectrometry and its Applications
201446 citationsauthor #2
Growth charts for patients with Hunter syndrome
201444 citationsauthor #5
Enzyme replacement therapy in newborn mucopolysaccharidosis IVA mice: early treatment rescues bone lesions?
201435 citationsauthor #9
Morquio A syndrome: diagnosis and current and future therapies.
201466 citationsauthor #5
Establishment of Glycosaminoglycan Assays for Mucopolysaccharidoses
201467 citationsauthor #2
Newborn screening and diagnosis of mucopolysaccharidoses: application of tandem mass spectrometry.
201426 citationsauthor #6
Impact of enzyme replacement therapy and hematopoietic stem cell therapy on growth in patients with Hunter syndrome
201462 citationsauthor #6
Enzyme replacement therapy on hypophosphatasia mouse model
201414 citationsauthor #5
A Dietary Restriction Influences the Progression But Not the Initiation of MSG-Induced Nonalcoholic Steatohepatitis
201425 citationsauthor #10
Potent SIRT1 Enzyme-stimulating and Anti-glycation Activities of Polymethoxyflavonoids from Kaempferia parviflora
201422 citationsauthor #4
Novel heparan sulfate assay by using automated high-throughput mass spectrometry: Application to monitoring and screening for mucopolysaccharidoses.
201435 citationsauthor #1
Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.
201347 citationsauthor #1
Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.
201330 citationsauthor #1
CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with reduced CYP3A4 protein level and function in human liver microsomes.
201378 citationsauthor #4
Therapies of mucopolysaccharidosis IVA (Morquio A syndrome)
201329 citationsauthor #6
Newborn screening and diagnosis of mucopolysaccharidoses.
2013164 citationsauthor #5
Aging‐like skin changes in metabolic syndrome model mice are mediated by mineralocorticoid receptor signaling
201335 citationsauthor #10
Pathogenesis of Morquio A syndrome: an autopsied case reveals systemic storage disorder.
201380 citationsauthor #9
Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome
201349 citationsauthor #13
Pharmacokinetics of 6-shogaol, a pungent ingredient of Zingiberis Rhizoma, and the anti-inflammatory activity of its metabolite, 6-paradol
20136 citationsauthor #2
Puerariae flos alleviates metabolic diseases in Western diet-loaded, spontaneously obese type 2 diabetic model mice
20128 citationsauthor #2
Skin fragility in obese diabetic mice: possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinases
201246 citationsauthor #10
Tetrandrine prevents bone loss in sciatic-neurectomized mice and inhibits receptor activator of nuclear factor κB ligand-induced osteoclast differentiation.
201221 citationsauthor #5
Disposition Kinetics of Taxanes in Peritoneal Dissemination
201218 citationsauthor #2
The molecular mechanisms of the hepatoprotective effect of gomisin A against oxidative stress and inflammatory response in rats with carbon tetrachloride-induced acute liver injury.
201241 citationsauthor #2
Docking and QSAR comparative studies of polycyclic aromatic hydrocarbons and other procarcinogen interactions with cytochromes P450 1A1 and 1B1
201221 citationsauthor #4
Aging-Like Skin Changes Induced by Ultraviolet Irradiation in an Animal Model of Metabolic Syndrome
201231 citationsauthor #8
The Crude Extract from Puerariae Flower Exerts Antiobesity and Antifatty Liver Effects in High-Fat Diet-Induced Obese Mice
201213 citationsauthor #7
Polymethoxyflavonoids from Kaempferia parviflora induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation.
201248 citationsauthor #2
Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models.
201239 citationsauthor #1
Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases.
201151 citationsauthor #1
Preventive effect of geniposide on metabolic disease status in spontaneously obese type 2 diabetic mice and free fatty acid-treated HepG2 cells.
201192 citationsauthor #2
Preventive Effect of Boiogito on Metabolic Disorders in the TSOD Mouse, a Model of Spontaneous Obese Type II Diabetes Mellitus
201125 citationsauthor #1
Preventive Effect of Pine Bark Extract (Flavangenol) on Metabolic Disease in Western Diet-Loaded Tsumura Suzuki Obese Diabetes Mice
201119 citationsauthor #1
Salacia reticulata inhibits differentiation of 3T3-L1 adipocytes.
201132 citationsauthor #1
Advantages and Disadvantages of Hyperbaric Oxygen Treatment in Mice with Obesity Hyperlipidemia and Steatohepatitis
201126 citationsauthor #6
Effects of bezafibrate in nonalcoholic steatohepatitis model mice with monosodium glutamate-induced metabolic syndrome.
201141 citationsauthor #2
Preventive effects of Salacia reticulata on non-alcoholic fatty liver disease (NAFLD)/ non-alcoholic steatohepatitis (NASH) in monosodium glutamate treated mice
20112 citationsauthor #2
Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds.
201125 citationsauthor #1
Antiobesity effects of Kaempferia parviflora in spontaneously obese type II diabetic mice
201193 citationsauthor #2
Preventive effect of Terminalia bellirica on obesity and metabolic disorders in spontaneously obese type 2 diabetic model mice
201131 citationsauthor #2
A study of cardiovascular function in Tsumura Suzuki obese diabetes, a new model mouse of type 2 diabetes.
201011 citationsauthor #3

TIMELINE

1957 3 citations

1976 50 citations

1977 3 citations

1978 8 citations

1981 27 citations

1983 55 citations

1984 10 citations

1985 58 citations

1986 325 citations

1987 329 citations

1989 1,011 citations

1990 67 citations

1991 1,153 citations

1992 1,000 citations

1993 112 citations

1994 3,523 citations

1995 133 citations

1996 2,193 citations

1997 1,186 citations

1998 1,033 citations

1999 1,243 citations

2000 94 citations

2001 338 citations

2002 830 citations

2003 457 citations

2004 828 citations

2005 319 citations

2006 1,138 citations

2007 229 citations

2008 257 citations

2009 107 citations

2010 186 citations

2011 437 citations

2012 286 citations

2013 518 citations

2014 526 citations

2015 326 citations

2016 127 citations

2017 95 citations

2018 57 citations

2019 51 citations

2020 39 citations

2021 12 citations

2022 4 citations

Unknown 19 citations

T. Shimada

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