Marcos Malumbres

ORCID {0000-0002-0829-6315}

PROFILE

Homepage
https://malumbreslab.org/
ORCID
{0000-0002-0829-6315}
Affiliations
Vall d'Hebron Institute of Oncology (VHIO), ICREA Professor
Aliases
M Malumbres, M. Malumbres
Publication record
258 papers · 29,515 citations · H-index 75

PAPERS

p27Kip1 V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor–positive breast cancer
20231 citationsauthor #13
Correction to: CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation
20232 citationsauthor #10
Decoding protein methylation function with thermal stability analysis
20238 citationsauthor #12
Abstract P5-02-28: p27Kip1 V109G single-nucleotide polymorphism (SNP): pinpointing the hormone-receptor positive breast cancer subpopulation that requires CDK4/6 inhibitors in addition to endocrine therapy
20230 citationsauthor #10
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
202323 citationsauthor #17
miR-203 drives breast cancer cell differentiation
202310 citationsauthor #16
HOPE (SOLTI-1903) breast cancer study: real-world, patient-centric, clinical practice study to assess the impact of genomic data on next treatment decision-choice in patients with locally advanced or metastatic breast cancer
20232 citationsauthor #7
Haspin participates in AURKB recruitment to centromeres and contributes to chromosome congression in male mouse meiosis.
20228 citationsauthor #8
Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A
202211 citationsauthor #25
A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas
20223 citationsauthor #11
Abstract OT2-06-01: Solti-1903 HOPE: Real-world clinical practice study to assess the impact of using genomic data on the next treatment decision making-choice in patients with locally advanced or metastatic breast cancer in Spain
20220 citationsauthor #14
The MASTL/PP2A cell cycle kinase‐phosphatase module restrains PI3K‐Akt activity in an mTORC1‐dependent manner
202224 citationsauthor #14
Mitotic Checkpoint Imbalances in Familiar Cancer.
20223 citationsauthor #2
Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility
202213 citationsauthor #15
Mammalian CDC14 phosphatases control exit from stemness in pluripotent cells
202210 citationsauthor #18
Genetic interaction between PLK1 and downstream MCPH proteins in the control of centrosome asymmetry and cell fate during neural progenitor division
20229 citationsauthor #12
Bilallelic germline mutations in MAD1L1 induce a novel syndrome of aneuploidy with high tumor susceptibility
20221 citationsauthor #14
CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation
20227 citationsauthor #10
Expanding the Differentiation Potential of Already-Established Pluripotent Stem Cells.
20212 citationsauthor #2
USP7 limits CDK1 activity throughout the cell cycle
202131 citationsauthor #7
PLK1 regulates centrosome migration and spindle dynamics in male mouse meiosis
202126 citationsauthor #4
Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias
202114 citationsauthor #16
Haspin participates in Aurora phosphorylation at centromeres and contributes to chromosome congression in male mouse meiosis
20211 citationsauthor #7
Mammalian cell cycle cyclins.
2020132 citationsauthor #2
CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
2020130 citationsauthor #12
Effects of energy metabolism on the mechanical properties of breast cancer cells
202033 citationsauthor #4
Squamous differentiation requires G2/mitosis slippage to avoid apoptosis
20200 citationsauthor #5
Peer Review #1 of "The spindle assembly checkpoint and speciation (v0.1)"
20200 citationsauthor #1
Control of the Cell Cycle
20202 citationsauthor #1
Mechanisms of Sensitivity and Resistance to CDK4/6 Inhibition.
2020295 citationsauthor #2
Decision letter: PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107
20200 citationsauthor #1
Effects of energy metabolism on the mechanical properties of breast cancer cells
20202 citationsauthor #4
CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
202027 citationsauthor #12
Transient exposure to miR‐203 enhances the differentiation capacity of established pluripotent stem cells
202017 citationsauthor #22
miR-203 imposes an intrinsic barrier during cellular reprogramming by targeting NFATC2
20202 citationsauthor #7
Peer Review #1 of "The spindle assembly checkpoint and speciation (v0.2)"
20200 citationsauthor #1
Lack of adaptation to centriolar defects leads to p53-independent microcephaly in the absence of Cep135
20200 citationsauthor #13
Squamous differentiation requires G2/mitosis slippage to avoid apoptosis
202024 citationsauthor #5
Advice from Cell Press Reviewers.
20191 citationsauthor #9
Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma
201939 citationsauthor #9
A Compendium to the Phosphoregulation of Mitosis
20190 citationsauthor #5
p38γ is essential for cell cycle progression and liver tumorigenesis
201981 citationsauthor #30
Aurora A controls CD8+ T cell cytotoxic activity and antiviral response
20196 citationsauthor #6
Contribution of the mRNA binding protein CPEB4 in platelet biology through translational control
20190 citationsauthor #6
A novel microRNA-based strategy to expand the differentiation potency of stem cells
20190 citationsauthor #22
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
20197 citationsauthor #7
Cdk 4 promotes adipogenesis through PPAR γ activation
20193 citationsauthor #3
Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma
201911 citationsauthor #10
Molecular Basis of the Mechanisms Controlling MASTL*
20199 citationsauthor #12
A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells
201931 citationsauthor #5
Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets
201826 citationsauthor #13
Functional analysis of Mastl mutations in cancer.
20180 citationsauthor #3
CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
201862 citationsauthor #23
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas
20181 citationsauthor #12
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas
201813 citationsauthor #12
Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis.
201863 citationsauthor #6
Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells
201872 citationsauthor #12
PO-028 Effectiveness and molecular basis of CDK4/6 inhibition in combination with taxanes in pancreatic cancer
20180 citationsauthor #8
Study of the role of microRNAs in T-cell lymphoblastic lymphoma development through the regulation of expression of FBXW7 gene.
20180 citationsauthor #14
Effectiveness and molecular basis of CDK4/6 inhibition in combination with taxanes in pancreatic cancer.
20180 citationsauthor #6
Plk1 overexpression suppresses tumor development by inducing chromosomal instability
20180 citationsauthor #12
Myelopathy secondary to copper deficiency: The great imitator.
20182 citationsauthor #3
Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1
20187 citationsauthor #3
An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability
201853 citationsauthor #7
PO-030 Functional analysis of mastl mutations in cancer
20180 citationsauthor #4
CDK4/6 Inhibitors: What Is the Best Cocktail?
201818 citationsauthor #1
Plk1 overexpression induces chromosomal instability and suppresses tumor development
2018135 citationsauthor #12
Programmed mitophagy is essential for the glycolytic switch during cell differentiation
2017296 citationsauthor #10
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
201782 citationsauthor #14
Erratum: The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
20170 citationsauthor #11
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites
201724 citationsauthor #11
APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity
20179 citationsauthor #14
SnapShot: Phosphoregulation of Mitosis.
201716 citationsauthor #4
Fueling the Cell Division Cycle.
2017242 citationsauthor #2
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis
201753 citationsauthor #18
Welcome to our first issue...
20160 citationsauthor #1
E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation
201629 citationsauthor #4
microRNAs regulate TAL1 expression in T-cell acute lymphoblastic leukemia
201630 citationsauthor #6
CDK4/6 Inhibitors resTORe Therapeutic Sensitivity in HER²⁺ Breast Cancer.
201612 citationsauthor #1
The cell proliferation antigen Ki-67 organises heterochromatin
2016313 citationsauthor #16
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
201633 citationsauthor #23
Aurora A drives early signalling and vesicle dynamics during T-cell activation
201643 citationsauthor #10
E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation.
201616 citationsauthor #4
Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid
201623 citationsauthor #10
Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
2016459 citationsauthor #2
Author response: The cell proliferation antigen Ki-67 organises heterochromatin
20160 citationsauthor #16
Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner
201639 citationsauthor #7
Keeping Order in Anaphase.
20153 citationsauthor #1
Deregulated expression of Cdc6 in the skin facilitates papilloma formation and affects the hair growth cycle
201515 citationsauthor #8
CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
2015219 citationsauthor #11
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
2015102 citationsauthor #9
AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest
2015245 citationsauthor #19
A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain.
201562 citationsauthor #3
Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development
2015105 citationsauthor #13
Mitophagy in mitosis: More than a myth
201512 citationsauthor #5
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy
2015146 citationsauthor #13
An Atypical Oncogene Within the Atypical E2Fs.
20153 citationsauthor #2
Functional reprogramming of polyploidization in megakaryocytes.
201553 citationsauthor #9
Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis.
201530 citationsauthor #16
d Is an APC/C Cdh1 Substrate that Regulates Cerebellar Granule Cell Neurogenesis
20152 citationsauthor #16

TIMELINE

1991 1,317 citations

1992 1 citations

1993 108 citations

1994 58 citations

1996 83 citations

1997 75 citations

1998 416 citations

1999 86 citations

2000 578 citations

2001 712 citations

2002 870 citations

2003 3,176 citations

2004 846 citations

2005 1,850 citations

2006 796 citations

2007 1,771 citations

2008 1,711 citations

2009 4,425 citations

2010 633 citations

2011 2,091 citations

2012 743 citations

2013 944 citations

2014 1,971 citations

2015 1,043 citations

2016 997 citations

2017 722 citations

2018 452 citations

2019 188 citations

2020 664 citations

2021 74 citations

2022 89 citations

2023 46 citations

Marcos Malumbres

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