Brigitte Gasser

Impact of Oxygen Availability on the Organelle‐Specific Redox Potentials and Stress in Recombinant Protein Producing Komagataella phaffii
20251 citationsauthor #7
Protein production dynamics and physiological adaptation of recombinant Komagataella phaffii at near-zero growth rates
20249 citationsauthor #11
Knock-out of the major regulator Flo8 in Komagataella phaffii results in unique host strain performance for methanol-free recombinant protein production.
20244 citationsauthor #10
Synthetic activation of yeast stress response improves secretion of recombinant proteins.
202329 citationsauthor #5
Customizing amino acid metabolism of Pichia pastoris for recombinant protein production
202315 citationsauthor #10
Characterising the metabolic rewiring of extremely slow growing Komagataella phaffii
20232 citationsauthor #3
Systematic sequence engineering enhances the induction strength of the glucose-regulated GTH1 promoter of Komagataella phaffii
202311 citationsauthor #6
technoYeast: New technologies and developments from the Yeast world
20220 citationsauthor #1
Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion.
202226 citationsauthor #6
Two homologs of the Cat8 transcription factor are involved in the regulation of ethanol utilization in Komagataella phaffii
202110 citationsauthor #6
Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in yeast
20214 citationsauthor #3
Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris.
202123 citationsauthor #4
Microbial protein cell factories fight back?
202145 citationsauthor #18
Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in yeast
20210 citationsauthor #3
What makes Komagataella phaffii non-conventional?
20218 citationsauthor #7
Beyond alcohol oxidase: the methylotrophic yeast Komagataella phaffii utilizes methanol also with its native alcohol dehydrogenase Adh2
202131 citationsauthor #6
Biotechnology and Bioengineering: Volume 117, Number 6, June 2020
20200 citationsauthor #2
Microbe Profile: Komagataella phaffii: a methanol devouring biotech yeast formerly known as Pichia pastoris.
202031 citationsauthor #2
The Degree and Length of O‐Glycosylation of Recombinant Proteins Produced in Pichia pastoris Depends on the Nature of the Protein and the Process Type
202025 citationsauthor #5
Engineered Deregulation of Expression in Yeast with Designed Hybrid‐Promoter Architectures in Coordination with Discovered Master Regulator Transcription Factor
202020 citationsauthor #4
A subcellular proteome atlas of the yeast Komagataella phaffii
202022 citationsauthor #12
Komagataella phaffii YPS1-5 encodes the alpha-factor degrading protease Bar1.
20204 citationsauthor #2
Pseudohyphal differentiation in Komagataella phaffii: investigating the FLO gene family
202011 citationsauthor #7
13 Yeast Cell Factories
20200 citationsauthor #3
The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2
20190 citationsauthor #3
Slow growth rate triggered transition to a pseudohyphal lifestyle of the protein production host Pichia pastoris
20190 citationsauthor #5
Detection and Elimination of Cellular Bottlenecks in Protein-Producing Yeasts.
201928 citationsauthor #2
Engineering of alcohol dehydrogenase 2 hybrid‐promoter architectures in Pichia pastoris to enhance recombinant protein expression on ethanol
20191 citationsauthor #2
CRISPR/Cas9-Mediated Homology-Directed Genome Editing in Pichia pastoris.
201963 citationsauthor #4
The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2
2019265 citationsauthor #3
A synthetic Calvin cycle enables autotrophic growth in yeast
20192 citationsauthor #3
The secretome of Pichia pastoris in fed‐batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time
201927 citationsauthor #7
Disruption of vacuolar protein sorting components of the HOPS complex leads to enhanced secretion of recombinant proteins in Pichia pastoris
201931 citationsauthor #5
Digital humanities and digital social reading
201919 citationsauthor #4
Dissection of growth-rate- and cell-cycle-dependent gene regulation in P. pastoris
20180 citationsauthor #5
A yeast for all seasons - Is Pichia pastoris a suitable chassis organism for future bioproduction?
201847 citationsauthor #1
Metabolic engineering of Pichia pastoris.
2018208 citationsauthor #2
Characterizing vacuolar protein sorting pathways in the yeast Pichia pastoris
20180 citationsauthor #6
The impact of ERAD on recombinant protein secretion in Pichia pastoris (syn Komagataella spp.).
201829 citationsauthor #3
Yeast biomass formation from carbon dioxide by rational metabolic engineering of Pichia pastoris
20180 citationsauthor #2
Engineering vacuolar sorting pathways for efficient secretion of recombinant proteins
20180 citationsauthor #1
Identification and characterization of the Komagataella phaffii mating pheromone genes
201816 citationsauthor #5
Promoter and process engineering for recombinant protein production in Pichia pastoris towards simple, fast and methanol-free cultivation regimes and high product titers
20182 citationsauthor #6
Enlarging the synthetic biology toolbox for Pichia pastoris: Golden Gate cloning and CRISPR/Cas9
20180 citationsauthor #8
Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose‐regulated GTH1 promoter of Pichia pastoris
201836 citationsauthor #6
Production under the AOX1 promoter in methanol utilization negative Pichia pastoris: An efficient expression system for less intensive fermentation
20180 citationsauthor #2
Transcriptional engineering of the glyceraldehyde‐3‐phosphate dehydrogenase promoter for improved heterologous protein production in Pichia pastoris
201763 citationsauthor #3
Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation
201727 citationsauthor #2
GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris
2017142 citationsauthor #9
Biomarkers allow detection of nutrient limitations and respective supplementation for elimination in Pichia pastoris fed-batch cultures
201721 citationsauthor #4
Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris.
201742 citationsauthor #6
Systems biotechnology for protein production in Pichia pastoris
2017105 citationsauthor #4
Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastoris
201760 citationsauthor #4
Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function.
201675 citationsauthor #9
The bud tip is the cellular hot spot of protein secretion in yeasts
201613 citationsauthor #2
Industrial Microorganisms: Pichia pastoris
201616 citationsauthor #3
P2-1Studying epigenetic regulation in fast and slow growing Pichia pastoris
20160 citationsauthor #3
The bud tip is the cellular hot spot of protein secretion in yeasts
20161 citationsauthor #2
The vitamin‐sensitive promoter PTHI11 enables pre‐defined autonomous induction of recombinant protein production in Pichia pastoris
201639 citationsauthor #2
Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris
201662 citationsauthor #7
Molecular optimization of rabies virus glycoprotein expression in Pichia pastoris
201642 citationsauthor #4
Functional inclusion bodies produced in the yeast Pichia pastoris
201636 citationsauthor #2
Increasing pentose phosphate pathway flux enhances recombinant protein production in Pichia pastoris
20160 citationsauthor #7
Developing a promoter into a process
20160 citationsauthor #4
Industrial Microorganisms: Saccharomyces cerevisiae and other Yeasts
20162 citationsauthor #2
Modulating the mating behavior of Pichia pastoris
20160 citationsauthor #2
Systems-level organization of yeast methylotrophic lifestyle
20150 citationsauthor #24
Methanol regulated yeast promoters: production vehicles and toolbox for synthetic biology
201539 citationsauthor #1
Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level
201593 citationsauthor #7
Systems-level organization of yeast methylotrophic lifestyle
2015152 citationsauthor #24
Multistep processing of the secretion leader of the extracellular protein Epx1 in Pichia pastoris and implications for protein localization.
201526 citationsauthor #6
Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris
2015151 citationsauthor #3
Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level
20150 citationsauthor #7
Metabolomics sampling of Pichia pastoris revisited: rapid filtration prevents metabolite loss during quenching.
201518 citationsauthor #5
Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production
2014139 citationsauthor #14
From slow to fast: effects of growth rate on global gene expression and recombinant protein secretion in Pichia pastoris
20140 citationsauthor #4
Systems biology of Pichia pastoris
20140 citationsauthor #1
Sample preparation workflow for the liquid chromatography tandem mass spectrometry based analysis of nicotinamide adenine dinucleotide phosphate cofactors in yeast.
201422 citationsauthor #3
Optimizing secretion efficiency of industrially relevant recombinant proteins in Pichia pastoris by means of yeast surface display and cytometric sorting
20140 citationsauthor #3
Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion
201443 citationsauthor #8
Engineering of Protein Folding and Secretion—Strategies to Overcome Bottlenecks for Efficient Production of Recombinant Proteins
201499 citationsauthor #4
Cross-species comparison of recombinant protein secretion in CHO cells and Pichia pastoris
20140 citationsauthor #10
Expression of C-terminal Fab fragment variants: the host determines the best variant
20140 citationsauthor #1
Metabolic model-based prediction of engineering targets for increased production of heterologous proteins
20140 citationsauthor #11
Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins
201467 citationsauthor #7
Yeast biotechnology: teaching the old dog new tricks
2014102 citationsauthor #3
The lipidome and proteome of microsomes from the methylotrophic yeast Pichia pastoris.
201433 citationsauthor #5
Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
201439 citationsauthor #7
Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics.
2013138 citationsauthor #2
Identification and deletion of the major secreted protein of Pichia pastoris
201338 citationsauthor #5
Comparison of Osmotic Conditions Based on Integrative Analysis Methods
20130 citationsauthor #4
The secretory pathway: exploring yeast diversity.
2013223 citationsauthor #6
Repressible promoters – A novel tool to generate conditional mutants in Pichia pastoris
201345 citationsauthor #3
Pichia pastoris: protein production host and model organism for biomedical research.
2013221 citationsauthor #1
Accurate quantification of the redox-sensitive GSH/GSSG ratios in the yeast Pichia pastoris by HILIC–MS/MS
201339 citationsauthor #3
In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response
2013100 citationsauthor #5
Induction without methanol: novel regulated promoters enable high-level expression in Pichia pastoris
2013131 citationsauthor #6
Recombinant protein production 6 (Vienna, February 2011).
20130 citationsauthor #1
Integrative Analysis Methods for Omics Data
20120 citationsauthor #4
Pichia pastoris as a cell factory — examining the secretory capabilities
20120 citationsauthor #3

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