J. Pachter

Immuno-laser capture microdissection of perfusion-fixed mouse brain tissue coupled to RNA-seq.
20250 citationsauthor #5
Unveiling the immune surveillance role of extracellular vesicles
20240 citationsauthor #13
Proteomic interrogation of the meninges reveals the molecular identities of structural components and regional distinctions along the CNS axis
20235 citationsauthor #6
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis
202352 citationsauthor #13
The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration
202223 citationsauthor #3
The primary macrophage chemokine, CCL2, is not necessary after a peripheral nerve injury for macrophage recruitment and activation or for conditioning lesion enhanced peripheral regeneration
20221 citationsauthor #3
Mitofusin‐2 regulates leukocyte adhesion and β2 integrin activation
20217 citationsauthor #6
Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE
20216 citationsauthor #5
Mitofusin‐2 regulates leukocyte adhesion through the maturation of β2 integrin activation in differentiation
20210 citationsauthor #7
Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis.
20217 citationsauthor #10
Systemic TLR2 tolerance enhances central nervous system remyelination
201927 citationsauthor #9
Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model
201916 citationsauthor #6
The CCL 2 Synthesis Inhibitor Bindarit Targets Cells of the Neurovascular Unit , and Suppresses Experimental Autoimmune Encephalomyelitis
20193 citationsauthor #6
Biodegradable nanofiber-based piezoelectric transducer
2019220 citationsauthor #21
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
2018128 citationsauthor #4
Laser-Capture Microdissection and RNA Extraction from Perfusion-Fixed Cartilage and Bone Tissue from Mice Implanted with Human iPSC-Derived MSCs in a Calvarial Defect Model.
20183 citationsauthor #6
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
201817 citationsauthor #4
Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia
2017187 citationsauthor #19
Spatiotemporal resolution of spinal meningeal and parenchymal inflammation during experimental autoimmune encephalomyelitis.
201716 citationsauthor #6
Additional file 6: Figure S5. of Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles
20160 citationsauthor #8
Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles
201667 citationsauthor #8
Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles
20160 citationsauthor #8
Alterations in Tight Junction Protein and IgG Permeability Accompany Leukocyte Extravasation Across the Choroid Plexus During Neuroinflammation
201435 citationsauthor #3
Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation
20140 citationsauthor #3
Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation
20140 citationsauthor #7
Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation
201419 citationsauthor #3
Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of Multiple Sclerosis
2014145 citationsauthor #10
P-glycoprotein regulates trafficking of CD8+ T cells to the brain parenchyma
201450 citationsauthor #12
Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation
201468 citationsauthor #7
Novel 3D analysis of Claudin-5 reveals significant endothelial heterogeneity among CNS microvessels.
201367 citationsauthor #4
Bindarit, Inhibitor of CCL2 Synthesis, Protects Neurons Against Amyloid-β-Induced Toxicity
201341 citationsauthor #10
Endothelial Cell Heterogeneity of Blood–Brain Barrier Gene Expression: Analysis by LCM/qRT-PCR
20121 citationsauthor #4
The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis
20120 citationsauthor #7
Brain regional angiogenic potential at the neurovascular unit during normal aging.
201279 citationsauthor #4
Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus
201244 citationsauthor #6
The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis
201266 citationsauthor #7
Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan(®) low density array.
201218 citationsauthor #4
Active induction of experimental autoimmune encephalomyelitis by MOG35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus
201212 citationsauthor #6
Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR.
20115 citationsauthor #4
Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics.
201122 citationsauthor #6
The Blood–Brain Barrier: Geriatric Relevance of a Critical Brain–Body Interface
2010116 citationsauthor #2
Astrocyte- and Endothelial-Targeted CCL2 Conditional Knockout Mice: Critical Tools for Studying the Pathogenesis of Neuroinflammation
200927 citationsauthor #3
Endothelial cell heterogeneity of blood‐brain barrier gene expression along the cerebral microvasculature
200999 citationsauthor #3
Transcellular transport of CCL2 across brain microvascular endothelial cells
200892 citationsauthor #5
Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood-brain barrier gene expression in situ.
200829 citationsauthor #3
Analysis of mouse brain microvascular endothelium using immuno‐laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform‐mass spectrometry proteomics platform
200838 citationsauthor #5
Qualitative and quantitative analysis of monocyte transendothelial migration by confocal microscopy and three-dimensional image reconstruction
20078 citationsauthor #4
“In situ” translation: Use of the cytoskeletal framework to direct cell-free protein synthesis
20076 citationsauthor #2
Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease.
200771 citationsauthor #4
Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells.
2007180 citationsauthor #3
Isolation and culture of microvascular endothelial cells from murine spinal cord.
2006103 citationsauthor #2
Colloquium C06: The Blood Brain Barrier and it's Role in Immune Priviledge in the CNS in Health and Disease
20060 citationsauthor #1
CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2.
200575 citationsauthor #5
Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection.
200549 citationsauthor #2
Technical caveats in identifying the source of endothelial cells in cultures derived from brain microvessels
20050 citationsauthor #1
Where is the blood–brain barrier … really?
2005128 citationsauthor #3
Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells.
2004142 citationsauthor #2
Caveolin-1 Knockdown by Small Interfering RNA Suppresses Responses to the Chemokine Monocyte Chemoattractant Protein-1 by Human Astrocytes*
200463 citationsauthor #2
Culture of murine brain microvascular endothelial cells that maintain expression and cytoskeletal association of tight junction-associated proteins
2003112 citationsauthor #2
The Blood‐Brain Barrier and Its Role in Immune Privilege in the Central Nervous System
2003275 citationsauthor #1
Chemokines and Chemokine Receptors along the Brain Microvasculature
20022 citationsauthor #2
Functional expression of CCR2 by human fetal astrocytes
200272 citationsauthor #5
/ 3-1 nternexin , a Protein Ubiquitous Intermediate Filament-associated
20020 citationsauthor #2
The Chemokine Receptor CCR2 Mediates the Binding and Internalization of Monocyte Chemoattractant Protein-1 along Brain Microvessels
200198 citationsauthor #4
Engagement of the scavenger receptor is not responsible for beta-amyloid stimulation of monocytes to a neurocytopathic state.
200014 citationsauthor #3
Inflammation and Alzheimer's disease.
20004,585 citationsauthor #22
Inflammation and Alzheimer's disease.
2000269 citationsauthor #22
Open peer commentary Inflammation and Alzheimer's disease
20000 citationsauthor #20
Visualization of beta‐amyloid peptide (Aβ) phagocytosis by human mononuclear phagocytes: dependency on Aβ aggregate size
200025 citationsauthor #2
Monocyte:astrocyte interactions regulate MCP‐1 expression in both cell types
200049 citationsauthor #3
Characterization of Binding Sites for Chemokines MCP‐1 and MIP‐1α on Human Brain Microvessels
200074 citationsauthor #2
Expression of binding sites for β chemokines on human astrocytes
199974 citationsauthor #5
Expression of binding sites for beta chemokines on human astrocytes.
199930 citationsauthor #5
Visualization of Chemokine Binding Sites on Human Brain Microvessels
199990 citationsauthor #3
Engagement of the scavenger receptor is not responsible for beta amyloid-induced monocyte neurotoxicity
19980 citationsauthor #3
Human astrocytes express chemokine binding sites
19980 citationsauthor #3
Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease
199836 citationsauthor #2
Chemokine binding sites on human brain microvessels
19981 citationsauthor #2
Phagocytosis of beta-amyloid: A possible requisite for neurotoxicity
19981 citationsauthor #8
Macrophages/microglial cells in human central nervous system during development: an immunohistochemical study
1998128 citationsauthor #3
Actin Depolymerization Is Developmentally Regulated in Rat Type II Cells Exposed to Terbutaline
199714 citationsauthor #3
Inflammatory mechanisms in Alzheimer disease: the role of beta-amyloid/glial interactions
199733 citationsauthor #1
Suppression of A beta-induced monocyte neurotoxicity by antiinflammatory compounds.
199715 citationsauthor #3
Adhesion of monocytic and astroglial cells: Effects of inflammatory mediators
19961 citationsauthor #2
A rapid and sensitive radioimmunoassay for the detection of human cytomegalovirus binding and infection of human fibroblasts.
19963 citationsauthor #3
Neurocytopathic effects of beta-amyloid-stimulated monocytes: a potential mechanism for central nervous system damage in Alzheimer disease.
199662 citationsauthor #3
Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro.
1995101 citationsauthor #3
Growth of brain microvessel endothelial cells on collagen gels: Applications to the study of blood-brain barrier physiology and CNS inflammation
199419 citationsauthor #2
Beta-actin mRNA-binding proteins associated with the cytoskeletal framework.
199315 citationsauthor #4
mRNA association with the cytoskeletal framework likely represents a physiological binding event
199220 citationsauthor #2
Association of mRNA with the cytoskeletal framework: its role in the regulation of gene expression.
199233 citationsauthor #1
Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides
1988144 citationsauthor #3
Intracellular distribution of mammalian stress proteins. Effects of cytoskeletal-specific agents.
198742 citationsauthor #2
Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs.
1987202 citationsauthor #1
alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues
1985103 citationsauthor #1
beta-Internexin, a ubiquitous intermediate filament-associated protein
198545 citationsauthor #2
Associated Proteins as Possible Cross‐Linkers in the Neuronal Cytoskeleton a
198511 citationsauthor #2
The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve.
1984171 citationsauthor #1
The Neuronal Cytoskeleton
198458 citationsauthor #1
A batchwise purification procedure of neurofilament proteins.
198352 citationsauthor #3

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