M. Chance

A multipronged footprinting map validates the predicted structure of stress biomarker Neuropeptide Y (NPY) and its binding with novel peptide binders.
20231 citationsauthor #5
Intact mass spectrometry screening to optimize hydroxyl radical dose for protein footprinting.
20233 citationsauthor #6
Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system
202311 citationsauthor #8
Multiplex Chemical Labeling of Amino Acids for Protein Footprinting Structure Assessment.
202215 citationsauthor #7
Utilization of Landscape of Kinases and Phosphosites To Predict Kinase-Substrate Association
20220 citationsauthor #4
Constructing Functional Networks of Phosphorylation Sites Using Co-Phosphorylation
20210 citationsauthor #3
GABARAP membrane conjugation sequesters the FLCN-FNIP tumor suppressor complex to activate TFEB and lysosomal biogenesis
20213 citationsauthor #21
New high-throughput endstation to accelerate the experimental optimization pipeline for synchrotron X-ray footprinting.
20219 citationsauthor #6
Structurally distinct external solvent-exposed domains drive replication of major human prions
20218 citationsauthor #7
Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution.
202031 citationsauthor #1
Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation.
202019 citationsauthor #5
Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism*
202037 citationsauthor #13
Proteins inform survival-based differences in patients with glioblastoma
20207 citationsauthor #15
Robust inference of kinase activity using functional networks
202064 citationsauthor #5
Time-resolved Conformational Analysis during GPCR-Gs Coupling
20201 citationsauthor #11
Co-Phosphorylation Networks Reveal Subtype-Specific Signaling Modules in Breast Cancer
20209 citationsauthor #2
Corrigendum: Myometrial Transcriptional Signatures of Human Parturition
20193 citationsauthor #7
Myometrial Transcriptional Signatures of Human Parturition
201938 citationsauthor #7
Assembly of a GPCR-G Protein Complex.
2019181 citationsauthor #13
Interplay of transcriptional signaling by progesterone, cyclic AMP, and inflammation in myometrial cells: implications for the control of human parturition.
201920 citationsauthor #6
Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains
201851 citationsauthor #12
CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis
201831 citationsauthor #7
Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells
20189 citationsauthor #5
Abstract 2698: Phosphoproteomics-guided anticancer drug combination design with a novel small-molecule PP2A activator
20181 citationsauthor #5
A metastable contact and structural disorder in the estrogen receptor transactivation domain
201842 citationsauthor #14
High-Resolution Hydroxyl Radical Protein Footprinting: Biophysics Tool for Drug Discovery.
201845 citationsauthor #2
Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor†,‡
201814 citationsauthor #6
Abstract 4220: Heterogeneous distribution of prognostic protein markers in glioblastoma
20180 citationsauthor #5
Structural basis of ligand interaction with atypical chemokine receptor 3
201790 citationsauthor #9
Abstract 4173: Drug target mutations as a mechanism of acquired resistance to small molecules activators of protein phosphatase 2a
20170 citationsauthor #9
Regulation of endothelial hemoglobin alpha expression by Kruppel-like factors
201717 citationsauthor #8
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
2017158 citationsauthor #43
The KSEA App: a web‐based tool for kinase activity inference from quantitative phosphoproteomics
2017232 citationsauthor #3
A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs.
201710 citationsauthor #5
Linearity of network proximity measures: implications for set-based queries and significance testing.
20171 citationsauthor #2
Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment*
201756 citationsauthor #2
A Practical Guide to iSPOT Modeling: An Integrative Structural Biology Platform.
201713 citationsauthor #3
A dynamical systems model of progesterone receptor interactions with inflammation in human parturition
201614 citationsauthor #3
During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy.
201639 citationsauthor #11
Recent Advances and Applications in Synchrotron X-Ray Protein Footprinting for Protein Structure and Dynamics Elucidation.
20165 citationsauthor #3
Development of the XFP beamline for x-ray footprinting at NSLS-II
20164 citationsauthor #6
Linearity of network proximity measures: implications for set‐based queries and significance testing
20169 citationsauthor #2
Proteome and Protein Network Analyses of Memory T Cells Find Altered Translation and Cell Stress Signaling in Treated Human Immunodeficiency Virus Patients Exhibiting Poor CD4 Recovery
201612 citationsauthor #9
Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth.
201614 citationsauthor #9
MoBaS on Phosphorylation Data
20160 citationsauthor #5
Abstract 3865: Therapeutic activation of protein phosphatase 2A for the treatment of lung cancer
20160 citationsauthor #14
Probing the structure of ribosome assembly intermediates in vivo using DMS and hydroxyl radical footprinting.
201632 citationsauthor #8
Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration
2015270 citationsauthor #21
Apigenin blocks IKKα activation and suppresses prostate cancer progression
201579 citationsauthor #5
Detection of structural waters and their role in structural dynamics of rhodopsin activation.
20150 citationsauthor #2
Proteomics of Carcinogen-Induced Tumor Development in Rats Consuming a Normal Diet
20150 citationsauthor #2
Tissue Specific Dysregulated Protein Subnetworks in Type 2 Diabetic Bladder Urothelium and Detrusor Muscle*
201519 citationsauthor #7
Abstract PR04: Cancer drug response networks built for comparative cancer pharmacogenomics identifies combination therapies for repositioning
20150 citationsauthor #6
MOBAS: identification of disease-associated protein subnetworks using modularity-based scoring
201524 citationsauthor #3
Erratum: Quantitative mapping of protein structure by hydroxyl radical footprinting mediated structural mass spectrometry: A protection factor analysis (Biophysical Journal (2015) 108(107-115))
20150 citationsauthor #3
Covalent Labeling Techniques for Characterizing Higher Order Structure of Monoclonal Antibodies
20157 citationsauthor #5
Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS)*
201546 citationsauthor #4
Abstract B124: Drugging the undruggable: development of small molecule activators of protein phosphatase 2A for cancer treatment
20150 citationsauthor #5
Characterizing monoclonal antibody structure by carboxyl group footprinting
201541 citationsauthor #9
Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P‐TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression
201523 citationsauthor #4
63,100-element oligonucleotide array activation revealed by profiling of psoriasis on the Novel mechanisms of T-cell and dendritic cell
20150 citationsauthor #9
Proteomic and bioinformatics profile of paired human alveolar macrophages and peripheral blood monocytes
201517 citationsauthor #9
Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart.
201526 citationsauthor #7
Efficiently Enumerating All Connected Induced Subgraphs of a Large Molecular Network
201427 citationsauthor #2
A Synchrotron-Based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Prefibrillar Intermediates with Residue-Specific Resolution
201429 citationsauthor #5
Reliable Determination of Site-Specific In Vivo Protein N-Glycosylation Based on Collision-Induced MS/MS and Chromatographic Retention Time
201440 citationsauthor #4
Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable It to Function as a Non-oligomerizing Chemokine*
201447 citationsauthor #5
Discovery of common sequences absent in the human reference genome using pooled samples from next generation sequencing
201424 citationsauthor #12
Characterizing monoclonal antibody structure by carbodiimide/GEE footprinting
20147 citationsauthor #9
MP1-18 MOLECULAR MECHANISMS AND DYSREGULATED SUB-NETWORKS FOR BLADDER DYSFUNCTION IN TYPE 2 DIABETIC MICE
20140 citationsauthor #4
Integrating phosphoproteomics in systems biology
201435 citationsauthor #2
Development of a microsecond X-ray protein footprinting facility at the Advanced Light Source.
201439 citationsauthor #4
Abstract 1616: Phosphoprotein enrichment pathway analysis tools for studying cancer signaling
20140 citationsauthor #6
Assessing collective disease association of multiple genomic loci
20140 citationsauthor #3
Visualizing the kinetic power stroke that drives proton-coupled Zn(II) transport
201496 citationsauthor #5
Chemokine Protein-3 / CCL 7 Enable It to Function as a Epitopes of Monocyte Chemoattractant Multiple Glycosaminoglycan-binding Molecular Biophysics :
20140 citationsauthor #5
Electron Microscopic and Proteomic Comparison of Terminal Branches of the Trigeminal Nerve in Patients with and without Migraine Headaches
201464 citationsauthor #6
Development of a High Throughput X-Ray Footprinting Facility at the Advanced Light Source to Study the Structure and Dynamics of Complex Biological Macromolecules
20140 citationsauthor #4
Proteomics of Skin Proteins in Psoriasis: From Discovery and Verification in a Mouse Model to Confirmation in Humans*
201449 citationsauthor #10
Synchrotron X-ray footprinting on tour.
201416 citationsauthor #5
Structural Basis for the Oligomerization-State Switch from a Dimer to a Trimer of an Engineered Cortexillin-1 Coiled-Coil Variant
20133 citationsauthor #5
Pathway Analyses and Understanding Disease Associations
201319 citationsauthor #2
SAHA enhances Proteostasis of epilepsy-associated α1(A322D)β2γ2 GABA(A) receptors.
201343 citationsauthor #4
Colorectal Cancer and Its Molecular Subsystems: Construction, Interpretation, and Validation
20131 citationsauthor #2
A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4)*
201325 citationsauthor #9
Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes
201391 citationsauthor #6
Structural Insights into the Dynamics of the TRPA1 Activation Mechanism
20130 citationsauthor #8
Abstract 3217: Identification of mutated peptides/proteins driving cancer phenotype utilizing improved shotgun proteomics and data analysis approaches.
20130 citationsauthor #4
Network Signatures of Survival in Glioblastoma Multiforme
201366 citationsauthor #8
Abstract 3660: Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition.
20131 citationsauthor #3
Plasma Proteome Analysis Reveals Overlapping, yet Distinct Mechanisms of Immune Activation in Chronic HCV and HIV Infections
201316 citationsauthor #11
Drug Intervention Response Predictions with Paradigm (DIRPP) Identifies Drug Resistant Cancer Cell Lines and Pathway Mechanisms of Resistance
201319 citationsauthor #7
Proteomics of early azoxymethane‐induced intestinal tumorigenesis in F344 rats consuming a normal diet.
20130 citationsauthor #2
Comparison of epigenetic profiles of human oral epithelial cells from HIV-positive (on HAART) and HIV-negative subjects
201317 citationsauthor #5
Algorithms for detecting complementary SNPs within a region of interest that are associated with diseases
20121 citationsauthor #4
Insights into Substrate Specificity and Metal Activation of Mammalian Tetrahedral Aspartyl Aminopeptidase*
201236 citationsauthor #3
Crystal Structure of Escherichia coli L-arabinose Isomerase (ECAI) complexed with Ribitol
20120 citationsauthor #4
Structure and dynamics of protein waters revealed by radiolysis and mass spectrometry
201243 citationsauthor #3
MAGNET: MicroArray Gene expression and Network Evaluation Toolkit
201213 citationsauthor #2
Molecular Networks and Complex Diseases
20120 citationsauthor #5

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