Yoshiro Saito

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Yoshiro Saito, Yoshi Saito
Publication record
451 papers · 18,320 citations · H-index 68

PAPERS

Validation of a genotyping technique for a surrogate marker of HLA-B∗58:01 for allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in the Japanese population.
20232 citationsauthor #7
Role of selenoprotein P expression in the function of pancreatic β cells: Prevention of ferroptosis-like cell death and stress-induced nascent granule degradation.
202218 citationsauthor #10
High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database.
202212 citationsauthor #7
Safety of selenium exposure and limitations of selenoprotein maximization: Molecular and epidemiologic perspectives.
202247 citationsauthor #4
Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation
202116 citationsauthor #13
Results of a nationwide survey of Japanese pharmacists regarding the application of pharmacogenomic testing in precision medicine
202113 citationsauthor #2
Importance of NUDT15 Polymorphisms in Thiopurine Treatments
202113 citationsauthor #2
Diverse cytoprotective actions of vitamin E isoforms- role as peroxyl radical scavengers and complementary functions with selenoproteins.
202134 citationsauthor #1
Identification of an endogenous long non-coding RNA that inhibits selenoprotein P translation- New regulatory mechanism of SeP translation
20210 citationsauthor #1
Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors.
20215 citationsauthor #7
Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-μm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging.
202117 citationsauthor #11
Bioanalysis of therapeutic monoclonal antibody by peptide adsorption-controlled LC-MS.
20212 citationsauthor #17
Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia
202124 citationsauthor #4
Associations Between Stevens–Johnson Syndrome and Infection: Overview of Pharmacoepidemiological Studies
202114 citationsauthor #2
Ossifying fibromyxoid tumor of buccal mucosa: Report of a rare case and review of the literature
20211 citationsauthor #2
Selenium Transport Mechanism via Selenoprotein P—Its Physiological Role and Related Diseases
202196 citationsauthor #1
Implementation of Pharmacogenomic Information on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
20212 citationsauthor #3
Efficacy Comparison for a Schizophrenia and a Dysuria Drug Among East Asian Populations: A Retrospective Analysis Using Multi-regional Clinical Trial Data
20211 citationsauthor #7
Analytical method validation for biomarkers as a drug development tool: points to consider.
202117 citationsauthor #17
Lipid peroxidation products as a mediator of toxicity and adaptive response - The regulatory role of selenoprotein and vitamin E.
202124 citationsauthor #1
A multilaboratory validation study of LC/MS biomarker assays for three lysophosphatidylcholines.
20213 citationsauthor #16
Imaging Mass Spectrometry (IMS) for drug discovery and development survey: Results on methods, applications and regulatory compliance.
20215 citationsauthor #17
Effects of serial cervical or tail blood sampling on toxicity and toxicokinetic evaluation in rats.
20209 citationsauthor #4
Hepatic Adaptation to Therapeutic Doses of acetaminophen: An Exploratory Study in healthy Individuals.
20208 citationsauthor #7
Plasma Lipid Profiling of Three Types of Drug-Induced Liver Injury in Japanese Patients: A Preliminary Study
202011 citationsauthor #22
Development of a bioanalytical method for an antisense therapeutic using high-resolution mass spectrometry.
202010 citationsauthor #18
The Association Between Concurrence of Infection and the Onset of Severe Eruption or Liver Injury in Patients Using Antipyretic Analgesics: A Matched, Nested Case-Control Study.
20201 citationsauthor #3
Lack of toxicological influences by microsampling (50 µL) from jugular vein of rats in a collaborative 28-day study.
20209 citationsauthor #14
Generic MS-based method for the bioanalysis of therapeutic monoclonal antibodies in nonclinical studies.
20205 citationsauthor #12
Statin Intolerance Clinical Guide 2018
202026 citationsauthor #9
A case of inverted ductal papilloma of the buccal mucosa
20200 citationsauthor #5
Hydrogen Peroxide Causes Cell Death via Increased Transcription of HOXB13 in Human Lung Epithelial A549 Cells
20203 citationsauthor #4
Association of HLA-A*11:01 with sulfonamide-related severe cutaneous adverse reactions in Japanese patients.
202025 citationsauthor #20
Association of HLA-DRB1*04:05 allele with drug-induced interstitial lung disease in Japanese population
202017 citationsauthor #10
An Investigational Study to Establish the Basic Construction of Precision Medicine from a Pharmaceutical Perspective
20202 citationsauthor #2
Comparisons of PK/efficacy/safety data on drug labels among 3 East Asian countries
20200 citationsauthor #1
Case Report of a Clear-Cell Variant of Follicular Thyroid Carcinoma
20200 citationsauthor #4
2. Current Usage and Future Perspectives of Package Inserts for Prescription Drugs
20200 citationsauthor #2
A Study of 100 Cases of Cervical Schwannoma Treated with Inter-Capsular Resection
20208 citationsauthor #5
Selenoprotein P; P for Plasma, Prognosis, Prophylaxis, and More.
202028 citationsauthor #2
Clinical study designs and patient selection methods based on genomic biomarkers: Points-to-consider documents.
20200 citationsauthor #2
A Case of Bilateral Secondary Pneumothorax Shortly after the Completion of Concurrent Chemoradiotherapy for Tongue Cancer
20200 citationsauthor #1
Real‐world evidence of population differences in allopurinol‐related severe cutaneous adverse reactions in East Asians: A population‐based cohort study
20209 citationsauthor #9
Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses
202052 citationsauthor #4
Elucidation of the statistical factors that influence anti-drug antibody cut point setting through a multi-laboratory study.
20194 citationsauthor #17
Lipid Profile Characterization and Lipoprotein Comparison of Extracellular Vesicles from Human Plasma and Serum
201955 citationsauthor #3
Evaluating the impact of regulatory action on denosumab‐induced hypocalcaemia in Japan
20193 citationsauthor #14
Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation
20193 citationsauthor #8
Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans.
20194 citationsauthor #9
Association of HLA class I and II gene polymorphisms with acetaminophen-related Stevens–Johnson syndrome with severe ocular complications in Japanese individuals
201920 citationsauthor #3
Lipidomic Profiling of Plasma Samples in Patients with Newly Diagnosed Multiple Myeloma; A Biomarker Study for Predicting the Response and Toxicities of Melphalan, Prednisolone and Bortezomib (MPB) Regimen : An Ancillary Study of the JCOG1105 (JCOG1105A1)
20191 citationsauthor #5
Overall similarities and a possible factor affecting plasma metabolome profiles between venous and capillary blood samples from 20 healthy human males.
20196 citationsauthor #7
Lipidomic signatures of aortic media from patients with atherosclerotic and nonatherosclerotic aneurysms
201913 citationsauthor #15
Biomarker assay validation for clinical trials: a questionnaire survey to pharmaceutical companies in Japan.
20193 citationsauthor #12
Conference report: pharmacogenomics in special populations at WCP2018
20195 citationsauthor #3
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
20192 citationsauthor #1
Selenoprotein P as a significant regulator of pancreatic β cell function.
201938 citationsauthor #1
CHAPTER 4. Chemical Reactivity and Cellular Uptake of Tocopherols and Tocotrienols
20195 citationsauthor #1
Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients With Pulmonary Hypertension.
201916 citationsauthor #12
Population/regional differences in efficacy of 3 drug categories (antidiabetic, respiratory and psychotropic agents) among East Asians: A retrospective study based on multiregional clinical trials
20194 citationsauthor #9
Serum lipidomics for exploring biomarkers of bortezomib therapy in patients with multiple myeloma
201921 citationsauthor #8
Identification of a novel interaction of nephronectin with selenoprotein P
20190 citationsauthor #2
DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTEN.
201922 citationsauthor #6
Selenoprotein P as an in vivo redox regulator: disorders related to its deficiency and excess
201985 citationsauthor #1
Comprehensive lipid profiling of bleomycin‐induced lung injury
201920 citationsauthor #7
Acute Stage Longitudinal Change of Quality of Life from Pre- to 3 Months after Surgical Treatment in Head and Neck Cancer Patients
201912 citationsauthor #5
Application of Ion Chromatography Coupled with Mass Spectrometry for Human Serum and Urine Metabolomics
201914 citationsauthor #4
Response by Kikuchi et al Regarding Article, "Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: A Possible Novel Therapeutic Target".
20195 citationsauthor #3
Points-to-consider documents: Scientific information on the evaluation of genetic polymorphisms during non-clinical studies and phase I clinical trials in the Japanese population.
20182 citationsauthor #10
2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays).
201831 citationsauthor #55
Immunogenicity of therapeutic protein products: current considerations for anti-drug antibody assay in Japan.
201830 citationsauthor #7
Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: Possible Novel Therapeutic Target
201882 citationsauthor #12
The Medication Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Asians: The Major Drug Causality and Comparison With the US FDA Label
201862 citationsauthor #4
[Current Status of Health Foods Including Their Interactions with Drugs and Adverse Events].
20183 citationsauthor #1
Hydrogen Peroxide-Reducing Factor Released by PC12D Cells Increases Cell Tolerance against Oxidative Stress.
20180 citationsauthor #3
Current situation on biomarker validation in Japan.
20183 citationsauthor #1
Distribution of oxidized DJ-1 in Parkinson’s disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin
201838 citationsauthor #3
Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits.
201826 citationsauthor #1
Lipid profiling of pre-treatment plasma reveals biomarker candidates associated with response rates and hand–foot skin reactions in sorafenib-treated patients
201821 citationsauthor #5
HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians
201863 citationsauthor #8
Selenoprotein P as a regulator of pancreatic β cell function: Improving effects of neutralizing antibody
20180 citationsauthor #1
Identification of risk factors and development of detection algorithm for denosumab‐induced hypocalcaemia
20188 citationsauthor #10
Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation.
201811 citationsauthor #4
Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population
201854 citationsauthor #3
Low Levels of Amlodipine in Breast Milk and Plasma
20184 citationsauthor #4
Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies.
201812 citationsauthor #8
2018 White Paper on Recent Issues in Bioanalysis: focus on immunogenicity assays by hybrid LBA/LCMS and regulatory feedback (Part 2 - PK, PD & ADA assays by hybrid LBA/LCMS & regulatory agencies' inputs on bioanalysis, biomarkers and immunogenicity).
201820 citationsauthor #31
PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
201827 citationsauthor #13
6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
201856 citationsauthor #8
Association between dipeptidyl peptidase‐4 inhibitors and urinary tract infection in elderly patients: A retrospective cohort study
201810 citationsauthor #6
Comparison of different immunoassay methods to detect human anti-drug antibody using the WHO erythropoietin antibody reference panel for analytes.
201818 citationsauthor #6
Association of HLA-A*31: 01 Screening With the Incidence of Carbamazepine-Induced Cutaneous Adverse Reactions in a Japanese Population
201853 citationsauthor #30
Ether-phosphatidylcholine characterized by consolidated plasma and liver lipidomics is a predictive biomarker for valproic acid-induced hepatic steatosis.
201812 citationsauthor #5
2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis).
201822 citationsauthor #45
The skin as a metabolic and immune-competent organ: Implications for drug-induced skin rash
201822 citationsauthor #2
Factors influencing production of anti-drug antibodies against biopharmaceuticals in rheumatoid arthritis patients
20180 citationsauthor #6
Arachidonic acid‐containing phosphatidylcholine characterized by consolidated plasma and liver lipidomics as an early onset marker for tamoxifen‐induced hepatic phospholipidosis
201717 citationsauthor #6
Plasma Lipidomics of Healthy Japanese Adults Reveals Gender- and Age-Related Differences.
201712 citationsauthor #6
The mechanism of ER stress induction via selenium transport activity of excess Selenoprotein P in MIN6 cells, a model of pancreatic β cell
20170 citationsauthor #5
Effect of Infectious Diseases on the Pathogenesis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
201714 citationsauthor #7

TIMELINE

1970 4 citations

1971 1 citations

1991 0 citations

1994 22 citations

1995 14 citations

1998 0 citations

1999 273 citations

2000 36 citations

2001 466 citations

2002 1,017 citations

2003 993 citations

2004 2,457 citations

2005 2,210 citations

2006 777 citations

2007 988 citations

2008 785 citations

2009 871 citations

2010 1,425 citations

2011 671 citations

2012 708 citations

2013 627 citations

2014 829 citations

2015 385 citations

2016 499 citations

2017 645 citations

2018 690 citations

2019 361 citations

2020 223 citations

2021 287 citations

2022 77 citations

2023 2 citations

Yoshiro Saito

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