A. Bowcock

Correlation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal Melanoma
20227 citationsauthor #10
Author Correction: Integrated genomics point to immune vulnerabilities in pleural mesothelioma
20220 citationsauthor #21
Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase
20214 citationsauthor #15
Clinicopathological features and associations in a series of South African acral melanomas
20213 citationsauthor #5
Canonical and Interior Circular RNAs Function as Competing Endogenous RNAs in Psoriatic Skin
202115 citationsauthor #3
Integrated genomics point to immune vulnerabilities in pleural mesothelioma
202117 citationsauthor #21
CARD14‐associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature
202117 citationsauthor #6
Abstract 81: Studying Ghanian Cancer Genomes Using Cell-free DNA
20210 citationsauthor #21
The tumor genetics of acral melanoma: What should a dermatologist know?
202032 citationsauthor #3
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa
20207 citationsauthor #22
Global expression and CpG methylation analysis of primary endothelial cells before and after TNFa stimulation reveals gene modules enriched in inflammatory and infectious diseases and associated DMRs
202014 citationsauthor #6
CARD14-Mediated Psoriasis and Pityriasis Rubra Piliaris (PRP)
20200 citationsauthor #2
P-138 A comparison of the transcriptomic profiles of matched tissue from primary colorectal cancer and corresponding secondary lung metastases
20200 citationsauthor #20
Multiple therapeutic pathways in malignant mesothelioma identified by genomic mapping
20203 citationsauthor #21
Integrated genomics identify novel immunotherapy targets for malignant mesothelioma
20200 citationsauthor #21
CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation
202018 citationsauthor #6
Kinetics characterization of ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase
20200 citationsauthor #13
PD-L1 expression in pleomorphic lung carcinoma with STK11 mutations
20200 citationsauthor #8
Author response: CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation
20200 citationsauthor #6
MA23.10 Low Number of Mutations and Frequent Co-Deletions of CDKN2A and IFN Type I Characterize Malignant Pleural Mesothelioma
20192 citationsauthor #14
Intratumoral heterogeneity in PD-L1 expression in pleomorphic lung carcinoma: implications for management of stage III disease
20190 citationsauthor #11
Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity.
201915 citationsauthor #9
A Breath of Fresh Air: Opening up the Lung Cancer Genome.
20190 citationsauthor #1
MA23.11 Analysis of Immune Phenotype Composition in Malignant Pleural Mesothelioma (MPM) Using Bulk RNA Sequencing
20190 citationsauthor #13
P1.04-63 Correlation of Mutations in TP53, CDKN2A and PIK3CA with VISTA Expression in Pleomorphic Lung Carcinoma
20190 citationsauthor #13
Copy number variations in malignant pleural mesothelioma reveal novel regions of genomic imbalances
20180 citationsauthor #13
BAP1 DE‐UBIQUITINASE IS ALLOSTERICALLY REGULATED BY ASXL1/2: SOMATIC BAP1 MUTATION IN RCC AND OTHER TUMORS INACTIVE THIS REGULATION BY TARGETING MULTIPLE INDEPENDENT DOMAINS: PD46‐01
20180 citationsauthor #8
MA21.03 Heterogeneity in MET Copy Number and Intratumoural Subsets in Pleomorphic Lung Carcinoma: Implications for MET Directed Therapy in NSCLC
20180 citationsauthor #10
Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.
201825 citationsauthor #7
Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer
201844 citationsauthor #19
Targeted next-generation sequencing of malignant pleural mesothelioma identifies recurrent NRAS oncogene mutations
20180 citationsauthor #14
CARD14‐associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris
2018101 citationsauthor #18
Punctuated evolution of canonical genomic aberrations in uveal melanoma
2018180 citationsauthor #6
P1.17-019 B7-H3 Protein Expression in Thymic Epithelial Tumor Subtypes and Its Association with PD-L1 and Clinical Characteristics
20170 citationsauthor #7
Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment
201716 citationsauthor #22
Abstract 3390: Clonal evolution in uveal melanoma
20170 citationsauthor #8
Referee Acknowledgement for 2016
20170 citationsauthor #153
The Molecular Revolution in Cutaneous Biology: The Era of Genome-Wide Association Studies and Statistical, Big Data, and Computational Topics.
201713 citationsauthor #2
116: Somatic and germline mutations in thymic epithelial tumours and their correlation with histological and clinical phenotypes
20170 citationsauthor #7
55: Somatic BAP1 and NF2 mutations in pleural malignant mesothelioma and their correlation with clinical phenotype
20170 citationsauthor #13
OA 03.02 Comprehensive Characterization of Thymic Epithelial Tumor Subtypes Through an Analysis of Somatic Mutations and Copy Number Alterations
20170 citationsauthor #5
oligonucleotide array revealed by profiling of psoriasis on the 63,100-element Novel mechanisms of T-cell and dendritic cell activation
20160 citationsauthor #2
Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.
201663 citationsauthor #7
Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas
2016123 citationsauthor #8
Expression of PD-L1, PD-L2 and PD-1 in thymic epithelial tumours (TETs).
20160 citationsauthor #7
Correction: AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake (PLoS One.(2014)9:4 (e92948)Doi: 10.1371/journal.pone.0092948)
20161 citationsauthor #4
Comparison of the genetic profiles of primary colorectal cancers and their subsequent pulmonary metastases: Implications for targeted treatment.
20160 citationsauthor #15
Management of resectable colorectal lung metastases
201638 citationsauthor #3
CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts
201640 citationsauthor #16
394 Card14 knockin mouse model of psoriasis and psoriatic arthritis
20160 citationsauthor #7
Reproducible Novel Transcriptional Differences Between Psoriatic Lesional and Non-Lesional Skin Show Increased Inflammation and Metabolism.
20153 citationsauthor #8
The immunogenetics of Psoriasis: A comprehensive review.
2015544 citationsauthor #3
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
2015182 citationsauthor #30
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
2015304 citationsauthor #29
Management of resectable colorectal lung metastases
20150 citationsauthor #3
CARD14 Expression in Dermal Endothelial Cells in Psoriasis
201458 citationsauthor #9
AKT Inhibitors Promote Cell Death in Cervical Cancer through Disruption of mTOR Signaling and Glucose Uptake
201479 citationsauthor #4
Genome-wide association analysis of psoriatic arthritis
20143 citationsauthor #11
Meta-Analysis of the TNFAIP3 Region in Psoriasis Reveals a Risk Haplotype that is Distinct from Other Autoimmune Diseases
201435 citationsauthor #9
Phosphorylated NF-κB (pNF-κB) was upregulated in psoriatic skin and dermal pNF-κB co-localized with CARD14 + ECs.
20140 citationsauthor #9
Transfection of psoriasis-associated CARD14 mutations into dermal endothelial cells resulted in increased expression and of several chemokines.
20140 citationsauthor #9
Fine mapping of eight psoriasis susceptibility loci
201432 citationsauthor #12
Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes
2014219 citationsauthor #10
Biology of advanced uveal melanoma and next steps for clinical therapeutics
201489 citationsauthor #8
Increased expression of CARD14-modulated chemokines in psoriatic skin co-localized with dermal endothelial cells.
20140 citationsauthor #9
Immune activating effects of stimulation of TLR agonists and cytokines on keratinocytes from a patient with a CARD14 mediated pustular psoriasis (P6283)
20130 citationsauthor #7
Genome‐wide linkage scan for psoriasis susceptibility loci in multiplex Tunisian families
201320 citationsauthor #15
DNA copy number changes as diagnostic tools for lung cancer
201323 citationsauthor #1
Deletion of the activating NKG2C receptor and a functional polymorphism in its ligand HLA‐E in psoriasis susceptibility
201331 citationsauthor #5
Primary ciliary dyskinesia-causing mutations in Amish and Mennonite communities.
201331 citationsauthor #6
Runx Transcription Factors Repress Human and Murine c-Myc Expression in a DNA-Binding and C-Terminally Dependent Manner
201313 citationsauthor #6
Dermal CARD14 expression in psoriasis
20130 citationsauthor #6
Noncanonical microRNAs and endogenous siRNAs in normal and psoriatic human skin.
201348 citationsauthor #3
Protective Effect of Human Endogenous Retrovirus K dUTPase Variants on Psoriasis Susceptibility
201225 citationsauthor #12
Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.
2012354 citationsauthor #26
Psoriasis Patients Are Enriched for Genetic Variants That Protect against HIV-1 Disease
201267 citationsauthor #16
Mutations in the Novel Protein PRRT2 Cause Infantile Convulsions with Paroxysmal Kinesigenic Dyskinesia
201219 citationsauthor #38
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
2012581 citationsauthor #22
PSORS2 is due to mutations in CARD14.
2012395 citationsauthor #19
Mutations in the Novel Protein PRRT2 Cause Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsions (IN10-2.005)
201248 citationsauthor #5
Mutations in the gene PRRT2 cause paroxysmal kinesigenic dyskinesia with infantile convulsions.
2012249 citationsauthor #38
Targeting skin: vitiligo and autoimmunity.
201213 citationsauthor #1
Association of Cardiovascular and Metabolic Disease Genes with Psoriasis
201280 citationsauthor #8
Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity
2012524 citationsauthor #22
Use of pharmacogenomics in psoriasis
20117 citationsauthor #2
A Genetic Risk Score Combining Ten Psoriasis Risk Loci Improves Disease Prediction
201197 citationsauthor #6
Genome-wide meta-analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL
2011128 citationsauthor #16
Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response.
2011216 citationsauthor #11
Histone Deacetylase Inhibitors Induce Growth Arrest and Differentiation in Uveal Melanoma
2011268 citationsauthor #7
Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome.
2011252 citationsauthor #8
A subset of methylated CpG sites differentiate psoriatic from normal skin
2011160 citationsauthor #10
Influence of Crohn's Disease Risk Alleles and Smoking on Disease Location
201120 citationsauthor #3
Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.
2011432 citationsauthor #8
Meta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.
2011117 citationsauthor #38
Carriers of rare missense variants in IFIH1 are protected from psoriasis.
201075 citationsauthor #10
Association analyses identify six new psoriasis susceptibility loci in the Chinese population
2010326 citationsauthor #63
Psoriasis genetics: breaking the barrier.
2010252 citationsauthor #2
Genome-wide association studies and infectious disease.
201011 citationsauthor #1
Primary ciliary dyskinesia in Amish communities.
201018 citationsauthor #4
ZNF750 is a nuclear protein whose promoter sequence variants are found in psoriasis patients
20100 citationsauthor #3

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