F. Sladek

2A. Hepatocyte nuclear factor-4 receptors in GtoPdb v.2025.3
20250 citationsauthor #1
EP162 DIET HIGH IN LINOLEIC ACID INCREASES SUSCEPTIBILITY TO COLITIS IN MICE
20230 citationsauthor #17
P10-012-23 Impact of Various High Fat Diets on Intestinal Gene Expression in Mouse
20230 citationsauthor #7
HNF4α isoforms: the fraternal twin master regulators of liver function
202317 citationsauthor #4
Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine
202324 citationsauthor #3
2A. Hepatocyte nuclear factor-4 receptors in GtoPdb v.2023.1
20230 citationsauthor #1
Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice
202326 citationsauthor #17
Hepatic circadian and differentiation factors control liver susceptibility for fatty liver disease and tumorigenesis
20229 citationsauthor #11
HNF4α isoforms regulate the circadian balance between carbohydrate and lipid metabolism in the liver
202111 citationsauthor #14
Diet High in Soybean Oil Increases Susceptibility to Colitis in Mice
20211 citationsauthor #16
SUN-LB119 Role of HNF4a Isoforms in the Carbohydrate/Lipid Switch in the Liver and Responsiveness to AMPK
20200 citationsauthor #6
Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation.
202022 citationsauthor #6
Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice
202015 citationsauthor #15
SUN-101 Dysregulation of Hypothalamic Gene Expression by Soybean Oil Diets in Mice
20190 citationsauthor #12
SUN-023 HNF4a Isoforms Regulate the Circadian Balance between Carbohydrate and Fatty Acid Metabolism in the Liver
20190 citationsauthor #14
Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver
20198 citationsauthor #5
2A. Hepatocyte nuclear factor-4 receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
20190 citationsauthor #1
HNF4α-deficient Fatty Liver Provides a Permissive Environment for Sex-independent Hepatocellular Carcinoma.
201929 citationsauthor #6
Incompatibility of the circadian protein BMAL1 and HNF4α in hepatocellular carcinoma
201898 citationsauthor #13
Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human.
201815 citationsauthor #5
Can Inhibition of Soluble Epoxide Hydrolase Ameliorate Increased Susceptibility to DSS Induced Colitis in Soybean Oil Fed Mice?
20180 citationsauthor #7
Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice
201767 citationsauthor #12
Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs
201747 citationsauthor #5
Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer
201666 citationsauthor #10
Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver
201599 citationsauthor #7
Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells
201564 citationsauthor #11
Author response: Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer
20150 citationsauthor #10
NSIT: Novel Sequence Identification Tool
20141 citationsauthor #5
factor leads to chemokine gene expression Novel nuclear target for thrombin: activation of the Elk1 transcription
20130 citationsauthor #3
Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer
201281 citationsauthor #11
Additional file 3
201210 citationsauthor #112
The Transcription Factor Encyclopedia The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters
20120 citationsauthor #113
Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors
2012108 citationsauthor #5
HNF4α: a new biomarker in colon cancer?
201227 citationsauthor #3
The Transcription Factor Encyclopedia
2012145 citationsauthor #113
The yin and yang of proliferation and differentiation
20128 citationsauthor #1
The Transcription Factor Encyclopedia
20121 citationsauthor #112
What are nuclear receptor ligands?
2011170 citationsauthor #1
Nuclear Receptor HNF4α Binding Sequences are Widespread in Alu Repeats
201124 citationsauthor #6
Title Nuclear Receptor HNF 4 alpha Binding Sequences are Widespread in Alu Repeats Permalink
20110 citationsauthor #6
Use of phosphosphospecific pY 14 antibody to identify potential Src substrates
20110 citationsauthor #4
HNF4α--role in drug metabolism and potential drug target?
2010137 citationsauthor #2
Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays
2010181 citationsauthor #8
Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor
2009214 citationsauthor #9
Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs.
2009109 citationsauthor #9
Additional file 4
2009174 citationsauthor #112
Additional file 6
20092,125 citationsauthor #112
Expression of HNF-4α (MODY1), HNF-1β (MODY5), and HNF-1α (MODY3) proteins in the developing mouse pancreas
200838 citationsauthor #5
Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.
200875 citationsauthor #2
Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.
200815 citationsauthor #5
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters.
2007390 citationsauthor #4
Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization.
2007106 citationsauthor #9
Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4α (HNF4α) gene
200641 citationsauthor #8
Direct G Protein Modulation of Cav2 Calcium Channels
2006260 citationsauthor #75
International Union of Pharmacology. LXVI. Orphan Nuclear Receptors
2006223 citationsauthor #10
Tumor suppressor p53 down regulates the expression of hepatocyte nuclear factor 4 α
20060 citationsauthor #8
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.
2006176 citationsauthor #5
AMP-Activated Protein Kinase Is Involved in Endothelial NO Synthase Activation in Response to Shear Stress
2006222 citationsauthor #6
Tumour suppressor p 53 down-regulates the expression of the human hepatocyte nuclear factor 4 α ( HNF 4 α ) gene
20061 citationsauthor #8
Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.
200629 citationsauthor #8
Hepatocyte Nuclear Factor-4α Is Essential for Glucose-stimulated Insulin Secretion by Pancreatic β-Cells*
2006135 citationsauthor #10
Functional characterization of the HNF4alpha isoform (HNF4alpha8) expressed in pancreatic beta-cells.
200515 citationsauthor #7
Functional characterization of the HNF4α isoform (HNF4α8) expressed in pancreatic β-cells
200541 citationsauthor #7
Functional characterization of the HNF4a isoform (HNF4a8) expressed in pancreatic b-cells
20055 citationsauthor #7
Development of a Cancer-Targeted Tissue-Specific Promoter System
200443 citationsauthor #3
Nuclear Receptors as Drug Targets: New Developments in Coregulators, Orphan Receptors and Major Therapeutic Areas
200312 citationsauthor #1
MAP kinase phosphorylation‐dependent activation of Elk‐1 leads to activation of the co‐activator p300
2003172 citationsauthor #4
Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain
200297 citationsauthor #3
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity.
200256 citationsauthor #5
Identifying transcription factor binding sites through Markov chain optimization
2002101 citationsauthor #3
Developmentally Regulated N-terminal Variants of the Nuclear Receptor Hepatocyte Nuclear Factor 4α Mediate Multiple Interactions through Coactivator and Corepressor-Histone Deacetylase Complexes*
200271 citationsauthor #2
Desperately seeking...something.
200227 citationsauthor #1
Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.
200249 citationsauthor #6
Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4α in rat liver
200157 citationsauthor #4
Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver.
200128 citationsauthor #4
Hepatocyte Nuclear Factor 4α
2001145 citationsauthor #1
Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.
2000119 citationsauthor #9
Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression.
200039 citationsauthor #3
Modulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1
1999132 citationsauthor #1
A unified nomenclature system for the nuclear receptor superfamily
19991,174 citationsauthor #30
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.
199920 citationsauthor #1
1 α Receptor Hepatocyte Nuclear Factor 4 Variation in the F Domain of Nuclear and Coactivator Interaction by a Splicing Modulation of Transcriptional Activation
19995 citationsauthor #1
MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization.
199851 citationsauthor #1
Avoiding false positives in colony PCR.
199819 citationsauthor #3
The DNA Binding Domain of Hepatocyte Nuclear Factor 4 Mediates Cooperative, Specific Binding to DNA and Heterodimerization with the Retinoid X Receptor α*
199787 citationsauthor #2
Serine/threonine phosphorylation of orphan receptor hepatocyte nuclear factor 4.
199770 citationsauthor #4
Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization
199732 citationsauthor #3
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids.
1995221 citationsauthor #2
Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors
1995192 citationsauthor #4
Orphan receptor HNF-4 and bZip protein C/EBP alpha bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription.
1993102 citationsauthor #4
Theexpression patternofa Drosophila homologtothe mouse transcription factor HNF-4suggestsa determinative role ingutformation
19930 citationsauthor #1
Orphan receptor HNF-4 and liver-specific gene expression.
199317 citationsauthor #1
A transcriptional hierarchy involved in mammalian cell-type specification
1992422 citationsauthor #4
Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4.
19928 citationsauthor #5
Mechanisms of liver-specific gene expression.
199261 citationsauthor #1
Murine chromosomal location of four hepatocyte-enriched transcription factors: HNf-3α, HNF-3β, HNF-3γ, and HNF-4
199225 citationsauthor #5
Differential regulation of hepatocyte-enriched transcription factors explains changes in albumin and transthyretin gene expression among hepatoma cells.
199137 citationsauthor #3
For liver-enriched transcription factor
19913 citationsauthor #1
Facteur de transcription enrichi par extraits hepatiques
19910 citationsauthor #1
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.
19901,009 citationsauthor #1

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