M. Karperien

Aggregation and Gelation Behavior of Stereocomplexed Four-Arm PLA-PEG Copolymers Containing Neutral or Cationic Linkers
20235 citationsauthor #5
Steering Stem Cell Fate within 3D Living Composite Tissues Using Stimuli‐Responsive Cell‐Adhesive Micromaterials (Adv. Sci. 10/2023)
202318 citationsauthor #8
Choice of Protein, Not Its Amyloid-Fold, Determines the Success of Amyloid-Based Scaffolds for Cartilage Tissue Regeneration
20232 citationsauthor #2
Mapping RUNX2 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells
20231 citationsauthor #3
Steering Stem Cell Fate within 3D Living Composite Tissues Using Stimuli‐Responsive Cell‐Adhesive Micromaterials
20236 citationsauthor #8
Cartilage-On-Chip Platform For Drug Screening In Osteoarthritis
20231 citationsauthor #3
Bioluminescence imaging on-chip platforms for non-invasive high-content bioimaging.
202314 citationsauthor #7
Microfluidic Generation of Thin‐Shelled Polyethylene Glycol‐Tyramine Microgels for Non‐Invasive Delivery of Immunoprotected β‐Cells
20237 citationsauthor #9
The use of peptides, aptamers, and variable domains of heavy chain only antibodies in tissue engineering and regenerative medicine.
202311 citationsauthor #3
Emulating the chondrocyte microenvironment using multi-directional mechanical stimulation in a cartilage-on-chip.
202228 citationsauthor #3
INVESTIGATING THE MECHANO-IMMUNE RESPONSE OF CARTILAGE AND THE SYNOVIAL MEMBRANE USING A JOINT-ON-CHIP APPROACH
20220 citationsauthor #7
Chitosan and carboxymethyl cellulose-based 3D multifunctional bioactive hydrogels loaded with nano-curcumin for synergistic diabetic wound repair.
202265 citationsauthor #3
Lab on a Chip
20220 citationsauthor #3
Joint-on-chip platforms: entering a new era of in vitro models for arthritis
202263 citationsauthor #4
Injectable Hydrogels for Articular Cartilage and Nucleus Pulposus Repair: Status Quo and Prospects
202216 citationsauthor #4
Enzymatic co-crosslinking of star-shaped poly(ethylene glycol) tyramine and hyaluronic acid tyramine conjugates provides elastic biocompatible and biodegradable hydrogels
202241 citationsauthor #5
Kinetic characterization of SPR-based biomarker assays enables quality control, calibration free measurements and robust optimization for clinical application.
20224 citationsauthor #5
Injectable Cell-Laden Polysaccharide Hydrogels: In Vivo Evaluation of Cartilage Regeneration
20226 citationsauthor #6
High Titers of Low Affinity Antibodies in COVID-19 Patients Are Associated With Disease Severity
202224 citationsauthor #10
TARGETTING JOINT PAIN BY INTRA-ARTICULAR INJECTION OF DRUG DEPOTS RELEASING NGF NEUTRALIZING ANTIBODY FRAGMENTS
20220 citationsauthor #8
Mapping SOX9 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells
20212 citationsauthor #3
Tethering Cells via Enzymatic Oxidative Crosslinking Enables Mechanotransduction in Non‐Cell‐Adhesive Materials
202120 citationsauthor #12
Mechanical stimulation is a key component in the development of pericellular matrix around human chondrocytes
20213 citationsauthor #5
Engineering Cartilage Tissue by Co-culturing of Chondrocytes and Mesenchymal Stromal Cells.
20211 citationsauthor #6
Engineering of Optimized Hydrogel Formulations for Cartilage Repair
202118 citationsauthor #5
High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection
20216 citationsauthor #7
Clinically feasible multiplex biomarker assay for assessing joint health and stratifying osteoarthritis patient population
20211 citationsauthor #2
An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation
20213 citationsauthor #11
Injectable hydrogels functionalized with antibody fragments as intra-articular cytokine sinks neutralizing pro-catabolic cytokines
20211 citationsauthor #7
Tethering Cells via Enzymatic Oxidative Crosslinking Enables Mechanotransduction in Non‐Cell‐Adhesive Materials (Adv. Mater. 42/2021)
20211 citationsauthor #12
Protein Adsorption Enhances Energy Dissipation in Networks of Lysozyme Amyloid Fibrils
20218 citationsauthor #4
Analytically validated multiplex biomarker assay to advance development of therapies and enable early OA diagnosis
20200 citationsauthor #6
A High Cell-Bearing Capacity Multibore Hollow Fiber Device for Macroencapsulation of Islets of Langerhans.
20205 citationsauthor #8
Multivalency Enables Dynamic Supramolecular Host–Guest Hydrogel Formation
202042 citationsauthor #6
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2
202060 citationsauthor #16
Cartilage-on-chip: a multi-modal platform to study human chondrocyte’s response to mechanical stimuli
20209 citationsauthor #6
Intra-articular drug depots for controlled release of heavy chain only antibodies blocking joint inflammation
20202 citationsauthor #7
Synovial membrane on chip: a new tool to study co-culture response to mechanical stimulation
20200 citationsauthor #6
Presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection
202031 citationsauthor #7
Epigenetic priming of BMP-mediated osteogenesis and bone repair
20200 citationsauthor #14
Functional Expression of ZNF467 and PCBP2 Supports Adipogenic Lineage Commitment in Adipose-derived Mesenchymal Stem Cells.
20207 citationsauthor #4
supinfofinalfinalversion_adapted_for_resub_complete – Supplemental material for Autophagy Is Involved in Mesenchymal Stem Cell Death in Coculture with Chondrocytes
20200 citationsauthor #9
Autophagy Is Involved in Mesenchymal Stem Cell Death in Coculture with Chondrocytes
20204 citationsauthor #9
Monolithic microfluidic platform for exerting gradients of compression on cell-laden hydrogels, and application to a model of the articular cartilage
202048 citationsauthor #3
Single cell SOX9 dynamics reveals differential DNA binding in subpopulations of human chondrocytes
20202 citationsauthor #2
Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking.
202044 citationsauthor #9
In vitro degradation profiles and in vivo biomaterial–tissue interactions of microwell array delivery devices
202011 citationsauthor #7
Enzymatic outside-in cross-linking enables single-step microcapsule production for high-throughput three-dimensional cell microaggregate formation
202016 citationsauthor #6
In silico validation of a cartilage specific circadian clock: mutation of BMAL1 increased MMP expression
20192 citationsauthor #5
Heterospecific bivalent heavy chain only antibodies for targeting BMP7 to osteochondral lesions
20190 citationsauthor #5
Defining the baseline transcriptional fingerprint of rabbit hamstring autograft
20195 citationsauthor #6
Redox-responsive degradable prodrug nanogels for intracellular drug delivery by crosslinking of amine-functionalized poly(N-vinylpyrrolidone) copolymers.
201946 citationsauthor #4
Developing Hyaluronic Acid Microgels for Sustained Delivery of Platelet Lysate for Tissue Engineering Applications.
201928 citationsauthor #3
In Vitro Evaluation of Small Molecule Delivery into Articular Cartilage: Effect of Synovial Clearance and Compressive Load
20197 citationsauthor #5
An injectable platelet lysate-hyaluronic acid hydrogel supports cellular activities and induces chondrogenesis of encapsulated mesenchymal stem cells.
2019102 citationsauthor #5
Changes in Fluorescence Recovery After Photobleaching (FRAP) as an indicator of SOX9 transcription factor activity.
201915 citationsauthor #4
A highly sensitive multiplex biomarker assay for the early diagnosis of osteoarthritis
20193 citationsauthor #4
Changes in SOX9 and RUNX2 protein activity correlate to the health state of human primary chondrocytes
20192 citationsauthor #2
SP0151 MICROFABRICATION TECHNOLOGIES FOR CARTILAGE REPAIR
20190 citationsauthor #1
Prolonged intra-articular retention of mesenchymal stem cells by advanced microencapsulation
20190 citationsauthor #8
Human OA model technologies: “Joint-on-a-chip”
20191 citationsauthor #1
Mimicking the Articular Joint with In Vitro Models.
201940 citationsauthor #6
Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets
201917 citationsauthor #6
Spatiotemporal material functionalization via competitive supramolecular complexation of avidin and biotin analogs
201923 citationsauthor #8
The Expressions of Dickkopf-Related Protein 1 and Frizzled-Related Protein Are Negatively Correlated to Local Inflammation and Osteoarthritis Severity
201919 citationsauthor #8
On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials.
20196 citationsauthor #5
Cartilage-on-chip: a physiologically inspired platform to reproduce articular joint compression and shear strain
20190 citationsauthor #5
ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in healthy and disease.
201915 citationsauthor #12
Membranes for bioartificial pancreas : Macroencapsulation strategies
20181 citationsauthor #3
Molecular characterization of physis tissue by RNA sequencing.
201820 citationsauthor #8
Delivery of Positively Charged Proteins Using Hyaluronic Acid Microgels
20180 citationsauthor #3
SOX9 transcriptional activity is differentially regulated in healthy and osteoarthritic chondrocytes
20183 citationsauthor #3
Promoted Chondrogenesis of Cocultured Chondrocytes and Mesenchymal Stem Cells under Hypoxia Using In-situ Forming Degradable Hydrogel Scaffolds.
201830 citationsauthor #6
NKX3.2 plays a key role in regulating HIF1α-directed angiogenesis in chondrocytes
20182 citationsauthor #2
Nanoparticle Enhancement Cascade for Sensitive Multiplex Measurements of Biomarkers in Complex Fluids with Surface Plasmon Resonance Imaging
201817 citationsauthor #5
Single-Cell Microgels: Technology, Challenges, and Applications.
201879 citationsauthor #2
Mitochondrial changes of articular chondrocytes revealed by omics analyses
20180 citationsauthor #5
Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture
201843 citationsauthor #4
In-air microfluidics enables rapid fabrication of emulsions, suspensions, and 3D modular (bio)materials
2018185 citationsauthor #5
A new method for multiplex measurements of biomarkers in synovial fluid aspirates with high sensitivity and extensive quality control
20181 citationsauthor #3
Hydrolytically Labile Linkers Regulate Release and Activity of Human Bone Morphogenetic Protein-6
20183 citationsauthor #4
Ultrahigh-Throughput Production of Monodisperse and Multifunctional Janus Microparticles Using in-Air Microfluidics
201879 citationsauthor #3
An important step towards a prevascularized islet macroencapsulation device—effect of micropatterned membranes on development of endothelial cell network
201825 citationsauthor #4
RUNX2 and SOX9 protein mobility correlates to osteogenic and chondrogenic differentiation of mesenchymal stem cells
20183 citationsauthor #3
Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice
201873 citationsauthor #14
Different response of human chondrocytes from healthy looking areas and damaged regions to IL1β stimulation under different oxygen tension
201810 citationsauthor #5
Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development
201845 citationsauthor #9
Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments
201823 citationsauthor #4
Fibronectin and Collagen IV Microcontact Printing Improves Insulin Secretion by INS1E Cells
201814 citationsauthor #5
The Effects of the WNT-Signaling Modulators BIO and PKF118-310 on the Chondrogenic Differentiation of Human Mesenchymal Stem Cells
201838 citationsauthor #5
An important step towards a prevascularized islet microencapsulation device: in vivo prevascularization by combination of mesenchymal stem cells on micropatterned membranes
201818 citationsauthor #9
O‐Phenanthroline as modulator of the hypoxic and catabolic response in cartilage tissue‐engineering models
20172 citationsauthor #5
Centering Single Cells in Microgels via Delayed Crosslinking Supports Long-Term 3D Culture by Preventing Cell Escape.
201758 citationsauthor #4
Amyloid micronetworks for cartilage repair
20171 citationsauthor #2
Single Cell Microgel Based Modular Bioinks for Uncoupled Cellular Micro‐ and Macroenvironments
2017102 citationsauthor #7
Nitric Oxide Mediates Crosstalk between Interleukin 1β and WNT Signaling in Primary Human Chondrocytes by Reducing DKK1 and FRZB Expression
201734 citationsauthor #5
Computational Modeling of Complex Protein Activity Networks
20171 citationsauthor #3
Molecular Validation of Chondrogenic Differentiation and Hypoxia Responsiveness of Platelet-Lysate Expanded Adipose Tissue–Derived Human Mesenchymal Stromal Cells
201734 citationsauthor #13
Pancreatic islet macroencapsulation using microwell porous membranes
201751 citationsauthor #7
Trophic Effects of Mesenchymal Stem Cells in Tissue Regeneration
2017238 citationsauthor #6

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