P. Strålfors

Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue
202210 citationsauthor #8
A systems biology analysis of lipolysis and fatty acid release from adipocytes in vitro and from adipose tissue in vivo
20208 citationsauthor #4
Adiponectin is secreted via caveolin 1-dependent mechanisms in white adipocytes.
20209 citationsauthor #7
Insulin and β-adrenergic receptors mediate lipolytic and anti-lipolytic signalling that is not altered by type 2 diabetes in human adipocytes
201926 citationsauthor #4
Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes.
201820 citationsauthor #5
Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients
201611 citationsauthor #4
Scaffolding protein IQGAP1: an insulin-dependent link between caveolae and the cytoskeleton in primary human adipocytes?
201611 citationsauthor #4
Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes*
201629 citationsauthor #5
Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes
201624 citationsauthor #6
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State
201517 citationsauthor #5
Dominant negative inhibition data should be analyzed using mathematical modeling – re‐interpreting data from insulin signaling
20156 citationsauthor #4
A Miniature Graphene-based Biosensor for Intracellular Glucose Measurements
201535 citationsauthor #8
A Single Mechanism Can Explain Network-wide Insulin Resistance in Adipocytes from Obese Patients with Type 2 Diabetes*
201447 citationsauthor #6
Combining test statistics and models in bootstrapped model rejection: it is a balancing act
201410 citationsauthor #2
The Concentration of β-Carotene in Human Adipocytes, but Not the Whole-Body Adipocyte Stores, Is Reduced in Obesity
201449 citationsauthor #4
Diabetes Adipocytes from Obese Patients with Type Network-wide Insulin Resistance in A Single Mechanism Can Explain Molecular Bases of Disease :
20140 citationsauthor #1
The insulin-signaling network in human adipocytes, normally and in diabetes : role of signaling through ERK1/2
20140 citationsauthor #6
A two-dimensional bootstrap approach to model discrimination
20130 citationsauthor #3
A computational model of the interplay between postprandial lipid and glucose dynamics
20130 citationsauthor #4
Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes
201341 citationsauthor #6
Phosphorylation of IRS1 at Serine 307 in Response to Insulin in Human Adipocytes Is Not Likely to be Catalyzed by p70 Ribosomal S6 Kinase
201322 citationsauthor #6
Siri ADIPOCYTES INSULIN RESISTANCE IN HUMAN ANALYSES REVEAL MECHANISMS OF EXPERIMENTAL AND MODELING Insulin Signaling in Type 2 Diabetes : Molecular Bases of Disease
20130 citationsauthor #7
Insulin Signaling in Type 2 Diabetes
2013117 citationsauthor #7
muscle of obese Zucker rats Exercise training increases ERK2 activity in skeletal
20130 citationsauthor #17
Global differences in specific histone H3 methylation are associated with overweight and type 2 diabetes
20131 citationsauthor #6
Mechanistic explanations for counter‐intuitive phosphorylation dynamics of the insulin receptor and insulin receptor substrate‐1 in response to insulin in murine adipocytes
201213 citationsauthor #4
Insulin signaling - mathematical modeling comes of age.
201236 citationsauthor #3
Graphene-based Biosensor for Intracellular Glucose Measurements
20120 citationsauthor #7
Lipid composition of caveolae and of surrounding plasma membrane in rat adipocytes
20120 citationsauthor #8
Reduced content of cholesterol in caveolae of adipocytes from insulin resistant, obese, and diabetic Zucker fa/fa rats
20120 citationsauthor #5
Localization of adiponectin at the plasma membrane in caveolae of human adipocytes
20120 citationsauthor #3
Caveolins and caveolae, roles in insulin signalling and diabetes.
201256 citationsauthor #1
In human adipocytes the insulin receptor and IRS1 are localized in caveolae, and caveolae destruction makes cells resistant to insulin signaling for metabolic and mitogenic control
20120 citationsauthor #7
Zinc Oxide Nanorods and their Application to Intracellular Glucose Measurements
20124 citationsauthor #3
Multilevel-Modeling, Core Predictions, and the Concept of Final Conclusions
20112 citationsauthor #2
A Hierarchical Whole-body Modeling Approach Elucidates the Link between in Vitro Insulin Signaling and in Vivo Glucose Homeostasis*
201179 citationsauthor #6
Histone Variants and Their Post-Translational Modifications in Primary Human Fat Cells
201134 citationsauthor #2
Intracellular K$^+$ Determination With a Potentiometric Microelectrode Based on ZnO Nanowires
201130 citationsauthor #7
Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes--role of insulin and IGF-I receptors.
201130 citationsauthor #3
Functionalised ZnO-nanorod-based selective electrochemical sensor for intracellular glucose.
2010126 citationsauthor #6
Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-free Modeling Framework*
201097 citationsauthor #5
Attenuated mTOR Signaling and Enhanced Autophagy in Adipocytes from Obese Patients with Type 2 Diabetes
2010281 citationsauthor #9
An intracellular glucose biosensor based on nanoflake ZnO
2010133 citationsauthor #7
Growth and Structure of ZnO Nanorods on a Sub-Micrometer Glass Pipette and Their Application as Intracellular Potentiometric Selective Ion Sensors
201025 citationsauthor #4
P47 Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes – role of insulin and IGF-I receptors
20100 citationsauthor #3
Elucidating mechanisms of early insulin signaling in primary adipocytes and hepatocytes : a joint systems biology effort
20090 citationsauthor #4
Rapid Insulin-Dependent Endocytosis of the Insulin Receptor by Caveolae in Primary Adipocytes
2009113 citationsauthor #5
Creating a Bridge between Modelica and the Systems Biology Community
20096 citationsauthor #9
Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the beta3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes.
200950 citationsauthor #7
Short-Term Overeating Induces Insulin Resistance in Fat Cells in Lean Human Subjects
200939 citationsauthor #7
Functionalized zinc oxide nanorod with ionophore-membrane coating as an intracellular Ca2+ selective sensor
200961 citationsauthor #6
Putting the pieces together in diabetes research: towards a hierarchical model of whole-body glucose homeostasis.
200929 citationsauthor #2
Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes.
200820 citationsauthor #4
Core-Box Modeling in the Biosimulation of Drug Action
20081 citationsauthor #2
Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling
200848 citationsauthor #6
Erratum
20080 citationsauthor #6
ZnO nanorods as an intracellular pH sensor
20070 citationsauthor #7
Insulin-induced GLUT4 translocation to the plasma membrane is blunted in large compared with small primary fat cells isolated from the same individual
200797 citationsauthor #5
A new role for caveolae as metabolic platforms.
200747 citationsauthor #4
Human, but not rat, IRS1 targets to the plasma membrane in both human and rat adipocytes.
200717 citationsauthor #7
Retinol‐binding protein‐4 attenuates insulin‐induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes
2007144 citationsauthor #6
ZINC OXIDE NANORODS AS AN INTRACELLULAR pH SENSOR
20075 citationsauthor #7
Phosphorylation of IRS1 at serine 307 and serine 312 in response to insulin in human adipocytes.
200628 citationsauthor #3
Association and insulin regulated translocation of hormone-sensitive lipase with PTRF.
200654 citationsauthor #4
Hormonal Control of Reversible Translocation of Perilipin B to the Plasma Membrane in Primary Human Adipocytes*
200636 citationsauthor #3
PPAR-gamma response element activity in intact primary human adipocytes: effects of fatty acids.
200636 citationsauthor #4
PPAR-γ response element activity in intact primary human adipocytes: effects of fatty acids
200658 citationsauthor #4
Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes
200627 citationsauthor #6
Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions
200650 citationsauthor #6
Insulin signaling and caveolae
20055 citationsauthor #1
Glucose transport is equally sensitive to insulin stimulation, but basal and insulin-stimulated transport is higher, in human omental compared with subcutaneous adipocytes.
200517 citationsauthor #4
Chapter 8 Insulin Signaling and Caveolae
20054 citationsauthor #1
Triacylglycerol Is Synthesized in a Specific Subclass of Caveolae in Primary Adipocytes*
2005144 citationsauthor #5
Vectorial Proteomics
200510 citationsauthor #2
Subcutaneous adipocytes from obese hyperinsulinemic women with polycystic ovary syndrome exhibit normal insulin sensitivity but reduced maximal insulin responsiveness.
200518 citationsauthor #8
Attenuation of Insulin-stimulated Insulin Receptor Substrate-1 Serine 307 Phosphorylation in Insulin Resistance of Type 2 Diabetes*
200595 citationsauthor #4
Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level of phosphorylation of IRS1 in type 2 diabetes
200485 citationsauthor #7
Lipids and glycosphingolipids in caveolae and surrounding plasma membrane of primary rat adipocytes.
2004151 citationsauthor #8
Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes. Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control.
200498 citationsauthor #8
Expression of a mutant IRS inhibits metabolic and mitogenic signalling of insulin in human adipocytes.
200423 citationsauthor #8
Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes.
2004163 citationsauthor #3
N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes.
200411 citationsauthor #4
Cell surface orifices of caveolae and localization of caveolin to the necks of caveolae in adipocytes.
2003167 citationsauthor #7
Synthesis of inositol phosphoglycans containing thiol-terminated spacers for efficient coupling to maleimide functionalized solid phases or proteins
20024 citationsauthor #2
Transfection of human fatcells by electroporation
20020 citationsauthor #2
Insulin induces translocation of glucose transporter GLUT4 to plasma membrane caveolae in adipocytes
2002105 citationsauthor #4
Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control*
2001346 citationsauthor #4
Localization of the insulin receptor in caveolae of adipocyte plasma membrane
1999391 citationsauthor #10
[A national meeting for medical students--new pedagogic approach. High tempo visits to different scientific fields].
19980 citationsauthor #6
Insulin second messengers
199764 citationsauthor #1
Insulin-Stimulated Glucose Uptake Involves the Transition of Glucose Transporters to a Caveolae-Rich Fraction within the Plasma Membrane: Implications for Type II Diabetes
1996106 citationsauthor #3
Cytoplasmic CREB alpha-like antigens in specific regions of the rat brain.
19963 citationsauthor #3
Cytoplasmic CREBα-like Antigens in Specific Regions of the Rat Brain
19966 citationsauthor #3
Translocation of insulin-regulated glucose transporter is stimulated by long-chain 1,2-diacylglycerol in rat adipocytes.
19955 citationsauthor #3
Uptake and metabolism of long-chain 1,2-diacylglycerols by rat adipocytes and H4IIE hepatoma cells.
19952 citationsauthor #3
Isolation of phosphooligosaccharide/phosphoinositol glycan from caveolae and cytosol of insulin-stimulated cells
199537 citationsauthor #3
Inhibition of Raf-1 kinase expression abolishes insulin stimulation of DNA synthesis in H4IIE hepatoma cells.
199413 citationsauthor #4
Autolysis of isolated adipocytes by endogenously produced fatty acids
199027 citationsauthor #1
Phosphorylation control by insulin in adipocytes is interfered with at a post‐receptor step by phosphoinositol and glucosamine
19908 citationsauthor #1
Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.
198919 citationsauthor #1

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