K. Hirokawa

Viruses - a major cause of amyloid deposition in the brain
20233 citationsauthor #9
[Ⅳ. Dendritic Cell Immunotherapy as Pancreatic Cancer Treatment].
20220 citationsauthor #9
Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to Change
202233 citationsauthor #10
Parallel gold enhancement of quantum dots 565/655 for double-labelling correlative light and electron microscopy on human autopsied samples
20222 citationsauthor #6
Publisher Correction: Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
20210 citationsauthor #12
Digital mapping of Lewy bodies and neurites in alpha-synuclein stained large cerebral hemispheric sections from three patients with dementia with Lewy bodies showing psychotic manifestations: A pilot study.
20212 citationsauthor #3
NDT_A_264910 1311..1339
20210 citationsauthor #12
Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease
202113 citationsauthor #12
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease
20210 citationsauthor #5
Severe Dialysis-Related Amyloidosis Spared the Brain: An Autopsy Case of a Patient Receiving Hemodialysis for 41 Years.
20210 citationsauthor #9
Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
20219 citationsauthor #12
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease
202155 citationsauthor #5
Immunosenescence and Cancer Immunotherapy at Old Age: Basics
20203 citationsauthor #3
Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
20207 citationsauthor #10
Parallel enlargement of Marinesco bodies and nuclei and progressive deposition of p62 in pigmented neurons of the substantia nigra
20203 citationsauthor #5
Asymptomatic sinusitis as an origin of infection-related glomerulonephritis manifesting steroid-resistant nephrotic syndrome
20205 citationsauthor #7
Numerous ballooned neurons in a 94-year-old man with dementia with Lewy bodies.
20201 citationsauthor #5
Quantitative Assessment of Immunological Level Using Peripheral Blood Cells
20200 citationsauthor #1
Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer’s Disease
202030 citationsauthor #11
Immunosenescence is both functional/adaptive and dysfunctional/maladaptive
202083 citationsauthor #3
Comorbid argyrophilic grain disease in an 87-year-old male with spinocerebellar ataxia type 31 with dementia: a case report
20203 citationsauthor #4
How to demix Alzheimer-type and PSP-type tau lesions out of their mixture -hybrid approach to dissect comorbidity-
201919 citationsauthor #5
Assessment of Age-Related Decline of Immunological Function and Possible Methods for Immunological Restoration in Elderly
201911 citationsauthor #1
Age-Related Changes in Subpopulations of Peripheral Blood Lymphocytes in Healthy Japanese Population
20196 citationsauthor #4
Perspectives: Is Immunosenescence Clinically Relevant?
20190 citationsauthor #3
Title : Brainstem tau pathology in Alzheimer ’ s disease is characterized by increase of three repeat tau and independent of amyloid β Author Names
20190 citationsauthor #4
Frailty in Old Age Is Associated with Altered Cytokine Production in Response to TLR Ligation
20191 citationsauthor #6
Three-dimensional surface models of autopsied human brains constructed from multiple photographs by photogrammetry
201912 citationsauthor #5
Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody
20199 citationsauthor #6
Neuroendocrine-Immune Network and Its Age-Related Changes
20191 citationsauthor #1
Aging, Cancer, and Apoptosis in Animal Models and Clinical Settings
20190 citationsauthor #4
14-3-3 protein sigma isoform co-localizes with phosphorylated α-synuclein in Lewy bodies and Lewy neurites in patients with Lewy body disease.
201813 citationsauthor #3
Brainstem tau pathology in Alzheimer’s disease is characterized by increase of three repeat tau and independent of amyloid β
201880 citationsauthor #4
Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?
2018169 citationsauthor #7
Macroscopic Localized Subicular Thinning as a Potential Indicator of Amyotrophic Lateral Sclerosis
20183 citationsauthor #9
Time-dependent and lesion-dependent HMGB1-selective localization in brains of patients with cerebrovascular diseases.
201814 citationsauthor #3
Effects of chocolate containing Leuconostoc mesenteroides strain NTM048 on immune function: a randomized, double-blind, placebo-controlled trial
20185 citationsauthor #8
Reduced MIBG uptake under relative preservation of cardiac sympathetic nerve in four autopsy patients of CBD-tau without lewy pathology
20170 citationsauthor #13
14-3-3 protein sigma isoform co-localizes with phosphorylated α-synuclein in lewy bodies and lewy neurites of patients with lewy body disease
20170 citationsauthor #3
Three-Repeat Tau with Grain-Like Structures and Distribution in an 83-Year-Old Man
20170 citationsauthor #6
[A Case of Gallbladder Carcinoma Producing Alpha-Fetoprotein(AFP)with Metastatic Liver Tumor].
20171 citationsauthor #9
Role of TLR Polymorphisms in Aging and Age-Related Diseases
20170 citationsauthor #3
Immunomodulation in Middle‐Aged Humans Via the Ingestion of Physta® Standardized Root Water Extract of Eurycoma longifolia Jack—A Randomized, Double‐Blind, Placebo‐Controlled, Parallel Study
201618 citationsauthor #6
Improvement in Human Immune Function with Changes in Intestinal Microbiota by Salacia reticulata Extract Ingestion: A Randomized Placebo-Controlled Trial
201510 citationsauthor #7
An Autopsy Case of Dementia with Lewy Bodies with Vocal Cord Abductor Paralysis
20150 citationsauthor #6
Trade off situation between thymus and growth hormone: age-related decline of growth hormone is a cause of thymic involution but favorable for elongation of lifespan
201517 citationsauthor #1
Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology
201353 citationsauthor #2
Type 1-Immortalized Cells Syngeneic Human T-Cell Leukemia Virus T-Cell-Deficient Nude Rats Inoculated with Inhibition by Adoptive Immunotherapy in Lymphoproliferative Disease and Its Induction of Adult T-Cell Leukemia-Like
20130 citationsauthor #6
Slower immune system aging in women versus men in the Japanese population
2013175 citationsauthor #1
Slower immune system aging in women versus men in the Japanese population
20131 citationsauthor #1
Four-repeat tau-selective deposition in subthalamic nucleus and motor cortex in Alzheimer disease.
20133 citationsauthor #7
Myotonic dystrophy and lipoma: a new association
20122 citationsauthor #6
Correlative magnetic resonance imaging and autopsy findings in a patient with coagulation necrosis treated with tissue plasminogen activator.
20120 citationsauthor #8
Tangle evolution linked to differential 3- and 4-repeat tau isoform deposition: a double immunofluorolabeling study using two monoclonal antibodies
201131 citationsauthor #4
Depletion or Preservation of Cardiac Sympathetic Nerve – An Autopsy-Verified Contrast in Two Cases of Alzheimer’s Disease with or without Lewy Bodies
20105 citationsauthor #8
Neuro-Endocrine-Immune Network and its Age-Related Changes
20092 citationsauthor #1
Decline of T cell-related immune functions in cancer patients and an attempt to restore them through infusion of activated autologous T cells.
200934 citationsauthor #1
Recreational music-making modulates immunological responses and mood states in older adults.
200944 citationsauthor #5
Sialidosis type I carrying V217M/G243R mutations in lysosomal sialidase: an autopsy study demonstrating terminal sialic acid in lysosomal lamellar inclusions and cerebellar dysplasia
200914 citationsauthor #6
Identification and tissue-specific expression of a novel isoform of Semaphorin 3D.
20094 citationsauthor #4
Aging, Cancer and Apoptosis in Animal Models and Clinical Settings
20090 citationsauthor #2
Expression of FOXP2 in the developing monkey forebrain: Comparison with the expression of the genes FOXP1, PBX3, and MEIS2
200872 citationsauthor #7
Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus
200822 citationsauthor #3
Expression of Foxp4 in the developing and adult rat forebrain
200862 citationsauthor #3
Experimental Allergic Sialadenitis in Mice
20070 citationsauthor #4
Immunosupportive therapies in aging
200762 citationsauthor #3
Scoring of Immunological Vigor: Trial Assessment of Immunological Status as a Whole for Elderly People and Cancer Patients
200713 citationsauthor #1
Recreational music-making modulates natural killer cell activity, cytokines, and mood states in corporate employees.
200747 citationsauthor #6
Forthcoming papers
20060 citationsauthor #17
This information is current as via CRTH 2 Receptor Chronic Allergic Inflammation of the Skin Plays an Essential Role in 2 Prostaglandin
20060 citationsauthor #12
Immunity and Aging
200613 citationsauthor #1
Importance of gastrointestinal ingestion and macromolecular antigens in the vein for oral tolerance induction
200616 citationsauthor #6
Prostaglandin D2 Plays an Essential Role in Chronic Allergic Inflammation of the Skin via CRTH2 Receptor1
2006197 citationsauthor #12
An autopsy case of a hemodialysis patient with multiple amyloidomas of the anus and several other organs
20060 citationsauthor #8
Induction of immunological tolerance by oral, but not intravenous and intraportal, administration of ovalbumin and the difference between young and old mice.
20069 citationsauthor #6
A Need to Study the Immune Status of Frail Older Adults
200617 citationsauthor #4
Expression of IAP‐family proteins in adult acute mixed lineage leukemia (AMLL)
200543 citationsauthor #8
Dysregulation of T-Cell Function in the Elderly
2005131 citationsauthor #5
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.
2005310 citationsauthor #7
DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70.
20055 citationsauthor #8
Age-related Decline of Brain Monoamines in Mice is Reversed to Young Level by Japanese Herbal Medicine
20052 citationsauthor #5
Cancer and aging: symposium of the 27th annual meeting of the Japanese society for biomedical gerontology, Tokyo
200511 citationsauthor #8
Resistance against Friend leukemia virus-induced leukemogenesis in DNA-dependent protein kinase (DNA-PK)-deficient scid mice associated with defective viral integration at the Spi-1 and Fli-1 site.
20057 citationsauthor #7
Monoclonal antibody to β peptide, recognizing amyloid deposits, neuronal cells and lipofuscin pigments in systemic organs
20047 citationsauthor #5
Regulation of osteoclastogenesis by three human RANKL isoforms expressed in NIH3T3 cells.
200454 citationsauthor #9
Differential expression of survivin in bone marrow cells from patients with acute lymphocytic leukemia and chronic lymphocytic leukemia.
200463 citationsauthor #7
Lewy bodies in the sinoatrial nodal ganglion: Clinicopathological studies
200443 citationsauthor #6
T-cell repertoire in a strain of transgenic C57BL/6 mice with the HLA-DRA gene on the X-chromosome
20042 citationsauthor #4
Expression of IAP family proteins in colon cancers from patients with different age groups
200467 citationsauthor #8
Expression level of Wnt signaling components possibly influences the biological behavior of colorectal cancer in different age groups.
200418 citationsauthor #6
Search for factors determining early decline of thymic function
20040 citationsauthor #1
Gene expression of CD24 core polypeptide molecule in normal rat tissues and human tumor cell lines
200448 citationsauthor #3
Expression of IAP family proteins in esophageal cancer.
200461 citationsauthor #7
Expression of IAP family proteins in myelodysplastic syndromes transforming to overt leukemia.
200469 citationsauthor #8
Immunohistological study of senile brains by using a monoclonal antibody recognizing β amyloid precursor protein: significance of granular deposits in relation with senile plaques
20048 citationsauthor #4
Different metastatic modes of malignant melanoma implanted in the ear of young and old mice
200413 citationsauthor #3
Immunohistochemical study on the liver in autopsy cases with disseminated intravascular coagulation (DIC) with reference to clinicopathological analysis
20045 citationsauthor #2
Establishment of a monoclonal antibody against senile plaques and its application for immunohistological and immunoelectron microscopical studies in the brain of the elderly
20046 citationsauthor #8
coq7/clk‐1 regulates mitochondrial respiration and the generation of reactive oxygen species via coenzyme Q
200442 citationsauthor #7
Age-related Decline of Brain Monoamines in Mice is Reversed to Young Level by Japanese Herbal Medicine
200417 citationsauthor #5

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