S. Przedborski

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Aliases
S Przedborski, S. Przedborski, Serge Przedborski, Serge E. Przedborski
Publication record
320 papers · 51,442 citations · H-index 115

PAPERS

Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson’s disease
202339 citationsauthor #7
RNA- and ATAC-sequencing Reveals a Unique CD83+ Microglial Population Focally Depleted in Parkinson’s Disease
20238 citationsauthor #19
Patterns of TDP‐43 Deposition in Brains with LRRK2 G2019S Mutations
202310 citationsauthor #12
Motoneuron Diseases.
20222 citationsauthor #2
Reply to: “Letter on Discussion of Gait Research”
20220 citationsauthor #12
Lipid level alteration in human and cellular models of alpha synuclein mutations
20220 citationsauthor #10
Lipid level alteration in human and cellular models of alpha synuclein mutations
202215 citationsauthor #10
Retromer dysfunction in amyotrophic lateral sclerosis
202215 citationsauthor #17
Non-cell-autonomous pathogenic mechanisms in amyotrophic lateral sclerosis.
202183 citationsauthor #3
The impact of COVID-19 and social distancing on people with Parkinson’s disease: a survey study
202175 citationsauthor #8
COVID-19 manifestations in people with Parkinson’s disease: a USA cohort
202120 citationsauthor #15
Sumoylation regulates the assembly and activity of the SMN complex
202114 citationsauthor #11
Recent Advances in the Development of Stem‐Cell‐Derived Dopaminergic Neuronal Transplant Therapies for Parkinson's Disease
202137 citationsauthor #4
Discussion of Research Priorities for Gait Disorders in Parkinson's Disease
202138 citationsauthor #12
SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence
202149 citationsauthor #26
Addressing the Challenges of Clinical Research for Freezing of Gait in Parkinson's Disease
202122 citationsauthor #7
COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital
2021336 citationsauthor #26
The impact of COVID-19 and social distancing on people with Parkinson’s disease: a survey study
20211 citationsauthor #8
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow
202038 citationsauthor #22
Preparing a neurology department for SARS-CoV-2 (COVID-19)
202054 citationsauthor #10
Amelioration of the nigrostriatal pathway facilitated by ultrasound-mediated neurotrophic delivery in early Parkinson's disease.
201963 citationsauthor #11
Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas.
2019133 citationsauthor #4
Role for VGLUT 2 in selective vulnerability of midbrain dopamine neurons
201915 citationsauthor #7
Decision letter: Mitochondrial fusion is required for spermatogonial differentiation and meiosis
20190 citationsauthor #1
Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson’s disease mouse model
201958 citationsauthor #7
Molsidomide provides neuroprotection against vincristine-induced peripheral neurotoxicity
20190 citationsauthor #9
PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation
201954 citationsauthor #8
Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo
201935 citationsauthor #10
Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons
201880 citationsauthor #7
Focused Ultrasound Enhanced Intranasal Delivery of Neurotrophic Factors Exhibit Neurorestorative Effects in Parkinson's Disease Mouse Model
20180 citationsauthor #4
Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas
20181 citationsauthor #4
A motif within the armadillo repeat of Parkinson’s-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway
201832 citationsauthor #8
The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form
201757 citationsauthor #8
PARKINSON'S DISEASE: molecular and therapeutic insights from model systems
201723 citationsauthor #2
Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy
2017704 citationsauthor #13
The two-century journey of Parkinson disease research
2017306 citationsauthor #1
Targeting α -synuclein for treating Parkinson’s disease: mechanistic and therapeutic considerations
201710 citationsauthor #4
Neuroinflammation in glaucoma: A new opportunity
2017221 citationsauthor #9
The Ubiquitination of PINK 1 Is Restricted to Its Mature 52-kDa Form Graphical Abstract Highlights
20170 citationsauthor #8
Focused-ultrasound Mediated Anti-Alpha-Synuclein Antibody Delivery for the Treatment of Parkinson's Disease
20178 citationsauthor #6
Axonal Degeneration: RIPK1 Multitasking in ALS.
201614 citationsauthor #2
5th International Symposium on Focused Ultrasound
201613 citationsauthor #22
Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults
201673 citationsauthor #5
Neuroprotection and neuroregeneration triggered through the FUS-induced opening of the blood-brain barrier in a Parkinson’s mouse model
20151 citationsauthor #5
α-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2
201591 citationsauthor #10
Novel subcellular localization for α-synuclein: possible functional consequences
201549 citationsauthor #4
c-jun-N-Terminal Kinase (JNK) for the Treatment of Amyotrophic Lateral Sclerosis
20150 citationsauthor #2
Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations.
2015417 citationsauthor #4
The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis.
201551 citationsauthor #14
From Man to Mouse: The MPTP Model of Parkinson Disease
20156 citationsauthor #4
Astrocyte mediated toxicity leads to motor neuron death in Spinal Muscular Atrophy (S17.006)
20150 citationsauthor #9
A new role for α‐synuclein in Parkinson's disease: Alteration of ER–mitochondrial communication
201567 citationsauthor #4
Parkinson’s disease: animal models and dopaminergic cell vulnerability
2014466 citationsauthor #2
A computational model of motor neuron degeneration.
2014150 citationsauthor #2
Necroptosis drives motor neuron death in models of both sporadic and familial ALS.
2014403 citationsauthor #17
α-Synuclein Is Localized to Mitochondria-Associated ER Membranes
2014475 citationsauthor #9
Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes.
2013204 citationsauthor #10
When Schwann cells conspire with mitochondria, neighboring axons are under attack by glia-derived neurotoxic lipids.
20135 citationsauthor #2
Pathogenesis of Parkinson's disease
2013197 citationsauthor #3
Mitophagy and Parkinson's disease: be eaten to stay healthy.
201394 citationsauthor #2
Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis
2013165 citationsauthor #13
Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy
2013125 citationsauthor #10
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition.
2012160 citationsauthor #7
Neuroprotective Small Molecules for the Treatment of Amyotrophic Lateral Sclerosis
20120 citationsauthor #1
3.14.1 MICROGLIA AND NEUROINFLAMMATION IN PD
20120 citationsauthor #1
Neurodegeneration and inflammation in Parkinson's disease.
2012248 citationsauthor #3
Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit.
2012155 citationsauthor #9
3.260 D-β-HYDROXYBUTYRATE IS NEUROPROTECTIVE IN MOUSE MODELS OF HUNTINGTON'S DISEASE
20120 citationsauthor #6
Animal models of Parkinson's disease.
2012118 citationsauthor #3
Parkinson's disease : a subject collection from Cold Spring Harbor perspectives in meicine
20121 citationsauthor #1
Pink1 and its Δψ -dependent cleavage product both localize to the outer mitochondrial membrane by a unique targeting mode*
20124 citationsauthor #4
3.205 NECDIN PREVENTS LOSS OF DOPAMINERGIC NEURONS IN ANIMAL MODELS OF PARKINSON'S DISEASE
20120 citationsauthor #3
The Role of the Innate Immune System in ALS
201248 citationsauthor #3
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease
2012497 citationsauthor #36
Classic and New Animal Models of Parkinson's Disease
2012512 citationsauthor #4
Mitochondrial Dynamics and Bioenergetic Dysfunction Is Associated with Synaptic Alterations in Mutant SOD1 Motor Neurons
2012134 citationsauthor #3
Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research
2012127 citationsauthor #41
Multimodal Actions of Neural Stem Cells in a Mouse Model of ALS: A Meta-Analysis
2012111 citationsauthor #22
3.7.3 ANIMAL MODELS OF PD
20120 citationsauthor #1
Mitophagy in cells with mtDNA mutations
201220 citationsauthor #3
Pink1 Kinase and Its Membrane Potential (Δψ)-dependent Cleavage Product Both Localize to Outer Mitochondrial Membrane by Unique Targeting Mode*
201292 citationsauthor #4
Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies.
201252 citationsauthor #5
Mitochondria: The Next (Neurode)Generation
2011560 citationsauthor #2
A tale on animal models of Parkinson's disease
2011164 citationsauthor #2
Pre-Clinical Testing of New Hydroxybutyrate Analogues
20110 citationsauthor #1
Can we reverse alpha‐synuclein lesions?
20111 citationsauthor #1
Can a defect in bioenergetics be involved in the pathogenesis of Parkinson's disease after all?
20110 citationsauthor #1
Mitophagy: the latest problem for Parkinson's disease.
2011160 citationsauthor #2
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease
201178 citationsauthor #10
D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease
201181 citationsauthor #6
New insights into the pathophysiology of dystonia
20110 citationsauthor #1
MPTP and Oxidative Stress: It’s Complicated!
20111 citationsauthor #5
Inflammation and Parkinson's disease pathogenesis
201089 citationsauthor #1
Interaction of Synuclein and Inflammation in Dopaminergic Neurodegeneration
20100 citationsauthor #1
PINK1/Parkin direct mitochondria to autophagy
201057 citationsauthor #4
Apoptosis‐inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins
201058 citationsauthor #6
Is amyotrophic lateral sclerosis a mitochondrial channelopathy?
20109 citationsauthor #2
Glutamate pathway implication in amyotrophic lateral sclerosis: what is the signal in the noise?
201017 citationsauthor #4
What can pluripotent stem cells teach us about neurodegenerative diseases?
201048 citationsauthor #2
Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease
2010434 citationsauthor #4

TIMELINE

1984 21 citations

1988 25 citations

1989 266 citations

1990 143 citations

1991 760 citations

1992 495 citations

1993 359 citations

1994 539 citations

1995 1,122 citations

1996 896 citations

1997 1,072 citations

1998 1,228 citations

1999 2,307 citations

2000 1,860 citations

2001 3,052 citations

2002 3,402 citations

2003 10,343 citations

2004 1,575 citations

2005 2,368 citations

2006 1,163 citations

2007 3,060 citations

2008 2,787 citations

2009 2,672 citations

2010 897 citations

2011 1,045 citations

2012 2,279 citations

2013 790 citations

2014 1,494 citations

2015 682 citations

2016 100 citations

2017 1,329 citations

2018 113 citations

2019 358 citations

2020 92 citations

2021 675 citations

2022 32 citations

2023 57 citations

S. Przedborski

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