L. Skálová

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Aliases
L Skálová, L. Skálová,, Lenka Skalova, L Skalova, Lenka Skálová, L. V. Skalova, L. Skálová
Publication record
195 papers · 4,172 citations · H-index 34

PAPERS

Environment-like exposure of free-living stages of Haemonchus contortus to albendazole: The intra- and intergeneration stability of altered expression of UDP-glycosyl transferases and ABC-transporters.
20250 citationsauthor #6
Metabolomic and proteomic differences in susceptible and benzimidazole-resistant adult females and males of Haemonchus contortus
20250 citationsauthor #10
New derivatives of benzhydroxamic acid with nematocidal activity against Haemonchus contortus and Caenorhabditis elegans
20250 citationsauthor #13
Biotransformation of anthelmintics in nematodes in relation to drug resistance
20253 citationsauthor #8
Phylogenetic and transcriptomic study of aldo-keto reductases in Haemonchus contortus and their inducibility by flubendazole
20241 citationsauthor #6
Flubendazole carbonyl reduction in drug-susceptible and drug-resistant strains of the parasitic nematode Haemonchus contortus: changes during the life cycle and possible inhibition
20243 citationsauthor #9
Anthelmintics in the environment: Their occurrence, fate, and toxicity to non-target organisms.
202319 citationsauthor #4
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation.
202312 citationsauthor #11
Albendazole from ovine excrements in soil and plants under real agricultural conditions: Distribution, persistence, and effects.
20238 citationsauthor #8
Short-chain dehydrogenases in Haemonchus contortus: changes during life cycle and in relation to drug-resistance
20238 citationsauthor #4
Anthelmintic activity of European fern extracts against Haemonchus contortus
20239 citationsauthor #9
Albendazole from Ovine Excrements in Soil and Plants Under Real Agricultural Conditions: Distribution, Persistence, and Effects
20220 citationsauthor #8
The role of UDP-glycosyltransferases in xenobioticresistance
202241 citationsauthor #5
The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole
20225 citationsauthor #5
Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus.
202214 citationsauthor #8
Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation
20222 citationsauthor #11
Proof of the environmental circulation of veterinary drug albendazole in real farm conditions.
202118 citationsauthor #8
Soybean (Glycine max) Is Able to Absorb, Metabolize and Accumulate Fenbendazole in All Organs Including Beans
20213 citationsauthor #6
The ATP bioluminescence assay: a new application and optimization for viability testing in the parasitic nematode Haemonchus contortus
202112 citationsauthor #5
MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis.
20217 citationsauthor #6
Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation
20216 citationsauthor #8
The Effect of the Manure from Sheep Treated with Anthelmintics on Clover (Trifolium pratense)
20216 citationsauthor #3
The Uptake of Ivermectin and Its Effects in Roots, Leaves and Seeds of Soybean (Glycine max)
202014 citationsauthor #5
Pharmaceuticals in environment: the effect of ivermectin on ribwort plantain (Plantago lanceolata L.)
202022 citationsauthor #3
Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults
202024 citationsauthor #9
The Modulation of Phase II Drug-Metabolizing Enzymes in Proliferating and Differentiated CaCo-2 Cells by Hop-Derived Prenylflavonoids
202014 citationsauthor #5
The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)
20206 citationsauthor #7
UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus
202013 citationsauthor #7
The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells
202012 citationsauthor #3
Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions
20196 citationsauthor #2
The Selection and Validation of Reference Genes for mRNA and microRNA Expression Studies in Human Liver Slices Using RT-qPCR
201911 citationsauthor #5
Ivermectin-induced changes in the expression of cytochromes P450 and efflux transporters in Haemonchus contortus female and male adults.
201926 citationsauthor #8
High-fructose drinks affect microRNAs expression differently in lean and obese mice.
201916 citationsauthor #3
The uptake, effects and biotransformation of monepantel in meadow plants used as a livestock feed.
20197 citationsauthor #7
Imatinib-induced changes in the expression profile of microRNA in the plasma and heart of mice-A comparison with doxorubicin.
201924 citationsauthor #9
Metabolism of the anthelmintic drug fenbendazole in Arabidopsis thaliana and its effect on transcriptome and proteome.
201915 citationsauthor #5
Phenotypic screening of the ‘Kurz-box’ of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus
201911 citationsauthor #11
beta-caryophyllene oxide and trans-nerolidol affect enzyme activity of CYP3A4 - in vitro and in silico studies.
201910 citationsauthor #3
Ivermectin biotransformation and impact on transcriptome in Arabidopsis thaliana.
201916 citationsauthor #6
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
20193 citationsauthor #7
Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells
201929 citationsauthor #4
Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats.
20198 citationsauthor #8
Anthelmintics in the future: current trends in the discovery and development of new drugs against gastrointestinal nematodes.
201977 citationsauthor #3
Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites
201837 citationsauthor #10
Inter-Individual Variability in Acute Toxicity of R-Pulegone and R-Menthofuran in Human Liver Slices and Their Influence on miRNA Expression Changes in Comparison to Acetaminophen
201819 citationsauthor #5
Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells
201845 citationsauthor #9
UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences
201834 citationsauthor #13
The impact of sesquiterpenes β-caryophyllene oxide and trans-nerolidol on xenobiotic-metabolizing enzymes in mice in vivo
201815 citationsauthor #3
A single adulticide dose of albendazole induces cytochromes P4501A in mouflon ( Ovis musimon) with dicrocoeliosis
20183 citationsauthor #8
MicroRNAs as Potential Regulators of Glutathione Peroxidases Expression and Their Role in Obesity and Related Pathologies
201854 citationsauthor #3
The metabolism of flubendazole in human liver and cancer cell lines.
201810 citationsauthor #9
MicroRNAs in the diagnosis and prevention of drug-induced cardiotoxicity
201838 citationsauthor #3
Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels
201820 citationsauthor #2
Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).
201824 citationsauthor #2
Flubendazole and mebendazole impair migration and epithelial to mesenchymal transition in oral cell lines.
201825 citationsauthor #6
The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines
201732 citationsauthor #6
Monosodium glutamate-induced obesity changed the expression and activity of glutathione S-transferases in mouse heart and kidney.
201712 citationsauthor #6
Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice
20178 citationsauthor #5
The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice.
201770 citationsauthor #9
The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro.
201762 citationsauthor #10
Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity
20177 citationsauthor #5
Hepatotoxicity of monoterpenes and sesquiterpenes
201791 citationsauthor #4
Biotransformation of Monepantel in Two Species Meadow Plants (Plantago Lanceolata and Campanula Rotundifolia)
20170 citationsauthor #4
Evaluation of drug uptake and deactivation in plant: Fate of albendazole in ribwort plantain (Plantago laceolata) cells and regenerants.
201725 citationsauthor #5
The Effect of Flubendazole on Adhesion and Migration in SW480 and SW620 Colon Cancer Cells.
201722 citationsauthor #2
Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions
201715 citationsauthor #10
Effect of Anthelmintics on Antioxidant Enzymes in Arabidopsis Thaliana
20170 citationsauthor #6
Phytotoxicity and Biotransformation of Fenbendazole in Ribwort
20170 citationsauthor #3
DIFFERENTIATED AND PROLIFERATING HUMAN INTESTINAL CELL LINE CACO2: DIFFERENCE IN ACTIVITY OF ANTIOXIDANT ENZYMES AND THEIR MODULATION BY SELECTED SESQUITERPENES
20160 citationsauthor #5
Metabolism of drugs and other xenobiotics in giant liver fluke (Fascioloides magna)
20167 citationsauthor #7
Veterinary drugs in the environment and their toxicity to plants.
2016243 citationsauthor #3
Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination
201628 citationsauthor #5
Comparison of biotransformation and efficacy of aminoacetonitrile anthelmintics in vitro.
20163 citationsauthor #8
Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity
201617 citationsauthor #10
Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro
201645 citationsauthor #5
Potential combination therapy of anticancer drugs with prenylflavonoids
20160 citationsauthor #4
Metabolic pathways of benzimidazole anthelmintics in harebell (Campanula rotundifolia).
201639 citationsauthor #3
The Role of Xenobiotic-Metabolizing Enzymes in Anthelmintic Deactivation and Resistance in Helminths.
201676 citationsauthor #4
Catechins Variously Affect Activities of Conjugation Enzymes in Proliferating and Differentiated Caco-2 Cells
20167 citationsauthor #3
Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice.
20159 citationsauthor #9
Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity.
201526 citationsauthor #3
Potential anti-cancer drugs commonly used for other indications.
201571 citationsauthor #2
Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment
201562 citationsauthor #2
Effect of oral administration of green tea extract in various dosage schemes on oxidative stress status of mice in vivo
201517 citationsauthor #2
The modulation of carbonyl reductase 1 by polyphenols
201523 citationsauthor #2
Essential Oil from Myrica rubra Leaves Potentiated Antiproliferative and Prooxidative Effect of Doxorubicin and its Accumulation in Intestinal Cancer Cells
201511 citationsauthor #7
Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus.
201519 citationsauthor #9
The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells
201563 citationsauthor #8
The effect of Myrica rubra essential oil and its components α-humulene and trans-nerolidol on adhesion and apoptosis of colorectal cancer cells
20156 citationsauthor #2
Drug-Metabolizing and Antioxidant Enzymes in Monosodium L-Glutamate Obese Mice
201516 citationsauthor #6
Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo.
201512 citationsauthor #10
Antioxidant, pro-oxidant and other biological activities of sesquiterpenes.
201496 citationsauthor #3
Effect of selected catechins on doxorubicin antiproliferative efficacy and hepatotoxicity in vitro
201418 citationsauthor #3
Essential oil from Myrica rubra leaves inhibits cancer cell proliferation and induces apoptosis in several human intestinal lines
201442 citationsauthor #11
Effect of Standardized Cranberry Extract on the Activity and Expression of Selected Biotransformation Enzymes in Rat Liver and Intestine
201410 citationsauthor #5
Biotransformation of anthelmintics and the activity of drug-metabolizing enzymes in the tapeworm Moniezia expansa
201411 citationsauthor #7
Metabolic pathways of anthelmintic drug monepantel in sheep and in its parasite (Haemonchus contortus).
201423 citationsauthor #8
In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb.
201422 citationsauthor #2
Reference Genes for Real-Time PCR Quantification of Messenger RNAs and MicroRNAs in Mouse Model of Obesity
201461 citationsauthor #6
Aerobic Fitness of Healthy Adults in Relation to Metabolomic and Transcriptomic Response to Acute Metabolic Challenges
20140 citationsauthor #8

TIMELINE

1963 0 citations

1977 0 citations

1997 3 citations

1998 9 citations

1999 45 citations

2000 39 citations

2001 47 citations

2002 21 citations

2003 80 citations

2004 446 citations

2005 65 citations

2006 67 citations

2007 74 citations

2008 147 citations

2009 174 citations

2010 71 citations

2011 128 citations

2012 178 citations

2013 240 citations

2014 324 citations

2015 335 citations

2016 465 citations

2017 344 citations

2018 324 citations

2019 259 citations

2020 105 citations

2021 52 citations

2022 62 citations

2023 56 citations

2024 4 citations

2025 3 citations

Unknown 10 citations

L. Skálová

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