S. Grzesiek

A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes.
202333 citationsauthor #10
The key role of glutamine for protein expression and isotopic labeling in insect cells
20235 citationsauthor #4
Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol
202229 citationsauthor #7
Nanobody GPS by PCS: An Efficient New NMR Analysis Method for G Protein Coupled Receptors and Other Large Proteins.
202214 citationsauthor #7
Preparation of a stable CCL5·CCR5·Gi signaling complex for Cryo-EM analysis.
20224 citationsauthor #6
Correspondence on "Synergy and Antagonism between Allosteric and Active-Site Inhibitors of Abl Tyrosine Kinase".
20224 citationsauthor #7
Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket
20223 citationsauthor #1
Efficient production of a functional G protein-coupled receptor in E. coli for structural studies
202112 citationsauthor #5
Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP
202026 citationsauthor #6
A high-resolution description of β1-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR
202052 citationsauthor #5
Versatile modules enable automated multi-column purifications on the ÄKTA pure chromatography system.
20209 citationsauthor #3
Solution structure of protein ARR_CleD in complex with c-di-GMP
20200 citationsauthor #5
Structural and Biochemical Studies Confirming the Mechanism of Action of Asciminib, an Agent Specifically Targeting the ABL Myristoyl Pocket (STAMP)
20209 citationsauthor #2
Rapid determination of general cell status, cell viability, and optimal harvest time in eukaryotic cell cultures by impedance flow cytometry
201921 citationsauthor #6
High pressure shifts the β1-adrenergic receptor to the active conformation in the absence of G protein.
201931 citationsauthor #3
Backbone 1H, 13C, and 15N Chemical Shift Assignments for the Hepatitis B Virus X protein (HBx)
20190 citationsauthor #2
Production of isotope-labeled proteins in insect cells for NMR
201863 citationsauthor #7
ATP Site Ligands Determine the Assembly State of the Abelson Kinase Regulatory Core via the Activation Loop Conformation.
201828 citationsauthor #5
Deuterium induces a distinctive Escherichia coli proteome that correlates with the reduction in growth rate
201818 citationsauthor #5
Author response: Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators
20170 citationsauthor #7
Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators
201756 citationsauthor #7
A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content.
201654 citationsauthor #7
Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor
2016169 citationsauthor #9
Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS
2016138 citationsauthor #7
Unraveling the complexity of protein backbone dynamics with combined (13)C and (15)N solid-state NMR relaxation measurements.
201528 citationsauthor #5
Backbone hydration determines the folding signature of amino acid residues.
201516 citationsauthor #3
An economic approach to efficient isotope labeling in insect cells using homemade 15N-, 13C- and 2H-labeled yeast extracts
201552 citationsauthor #3
NMR assignments and relaxation of 5P12-RANTES-E66S
20140 citationsauthor #2
Aromatic Amino Acids Promote Peptide Folding by Reducing Backbone Hydration
20140 citationsauthor #2
Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system
201422 citationsauthor #6
Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Promothiocin A in Complex with TipAS
20140 citationsauthor #5
Solid-state NMR of a protein in a precipitated complex with a full-length antibody.
201476 citationsauthor #9
1H, 13C and 15N assignments of Ubiquitin for both folded and denatured states at 258K and 2500 bar
20130 citationsauthor #4
Pressure & methanol-induced A-state of Ubiquitin
20130 citationsauthor #4
Characterization of structure, dynamics, and detergent interactions of the anti-HIV chemokine variant 5P12-RANTES.
201316 citationsauthor #3
High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin
201350 citationsauthor #4
WhiB7, an Fe-S-dependent Transcription Factor That Activates Species-specific Repertoires of Drug Resistance Determinants in Actinobacteria*
201355 citationsauthor #9
NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors
2013106 citationsauthor #5
Aromatic Amino Acids Confer Folding Propensities to a Nine-Residue Peptide
20130 citationsauthor #2
Kinase in Motion: Insights into the Dynamic Nature of p38α by High‐Pressure NMR Spectroscopic Studies
20139 citationsauthor #4
Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling.
20128 citationsauthor #4
Biophysical and structural investigation of bacterially expressed and engineered CCR5, a G protein-coupled receptor
201215 citationsauthor #5
Monocytes Contribute to Differential Immune Pressure on R5 versus X4 HIV through the Adipocytokine Visfatin/NAMPT
201238 citationsauthor #4
Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations.
201252 citationsauthor #5
Interactions of CCR5, the Main HIV Coreceptor, with Rantes and Other Ligands
20120 citationsauthor #7
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides.
201212 citationsauthor #5
In support of the BMRB
20129 citationsauthor #45
Sequence-specific mapping of the interaction between urea and unfolded ubiquitin from ensemble analysis of NMR and small angle scattering data.
201241 citationsauthor #4
Key stabilizing elements of protein structure identified through pressure and temperature perturbation of its hydrogen bond network.
201293 citationsauthor #2
Structure, Dynamics, Lipid Binding, and Physiological Relevance of the Putative GTPase-binding Domain of Dictyostelium Formin C*
201121 citationsauthor #6
Measurements of structural constraints
20110 citationsauthor #5
Site-specific measurement of slow motions in proteins.
2011110 citationsauthor #3
Solution Structure of the PilZ Domain Protein PA4608 Complex with Cyclic di-GMP Identifies Charge Clustering as Molecular Readout*♦
201185 citationsauthor #4
Measurement of Structural Restraints
20115 citationsauthor #5
Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.
201113 citationsauthor #4
Conformations in Urea-Denatured Ubiquitin and Protein G from 3 J Coupling Constants and Residual Dipolar Couplings
20100 citationsauthor #5
Measurement of site-specific 13C spin-lattice relaxation in a crystalline protein.
201096 citationsauthor #4
Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings.
201035 citationsauthor #5
Ensemble calculations of unstructured proteins constrained by RDC and PRE data: a case study of urea-denatured ubiquitin.
2010113 citationsauthor #2
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
201015 citationsauthor #4
Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors
2010568 citationsauthor #21
Backbone and stereospecific beta-sidechain assignments of 1H, 13C and 15N for Ubiquitin Unfolded in 8M Urea, pH2.5.
20100 citationsauthor #3
Backbone and stereospecific beta-sidechain assignments of 1H, 13C and 15N for Protein G Unfolded in 7.4M Urea, pH 2.0.
20100 citationsauthor #3
From biomolecular structure to functional understanding: new NMR developments narrow the gap.
200929 citationsauthor #1
L 3 Differences in the kinase binding modes of imatinib , nilotinib and dasatinib are reflected in Abl transphosphorylation assays
20090 citationsauthor #9
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings.
2009175 citationsauthor #6
DOTA-M8: An extremely rigid, high-affinity lanthanide chelating tag for PCS NMR spectroscopy.
2009143 citationsauthor #3
Structural analysis of B-Box 2 from MuRF1: identification of a novel self-association pattern in a RING-like fold.
200850 citationsauthor #7
Backbone NMR resonance assignment of the Abelson kinase domain in complex with imatinib
200827 citationsauthor #7
Crystal structure of the B2 box from MuRF1 in dimeric state
20080 citationsauthor #7
Backbone 1H, 15N, 13CO and 13CA resonance assignment of ABL kinase domain in complex with imatinib
20080 citationsauthor #7
Insights into the Low Adhesive Capacity of Human T-cadherin from the NMR Structure of Its N-terminal Extracellular Domain*
200834 citationsauthor #6
The signal transducer gp130: Solution structure of the carboxy‐terminal domain of the cytokine receptor homology region
200826 citationsauthor #8
Direct detection of N−H⋯N hydrogen bonds in biomolecules by NMR spectroscopy
200847 citationsauthor #4
Conformational distributions of unfolded polypeptides from novel NMR techniques.
200895 citationsauthor #3
Direct detection of N−H⋯O=C hydrogen bonds in biomolecules by NMR spectroscopy
200856 citationsauthor #4
Band-selective 1H-13C cross-polarization in fast magic angle spinning solid-state NMR spectroscopy.
200884 citationsauthor #6
Large-scale expression and purification of the major HIV-1 coreceptor CCR5 and characterization of its interaction with RANTES.
200831 citationsauthor #4
Solution Conformations and Dynamics of ABL Kinase-Inhibitor Complexes Determined by NMR Substantiate the Different Binding Modes of Imatinib/Nilotinib and Dasatinib*♦
2008198 citationsauthor #6
Minicollagen-15, a novel minicollagen isolated from Hydra, forms tubule structures in nematocysts.
200841 citationsauthor #5
Solution structure of the N-terminal extracellular domain of human T- cadherin
20080 citationsauthor #5
Structure and dynamics of 13C,15N-labeled lipopolysaccharides in a membrane mimetic.
200816 citationsauthor #4
Nematocyst outer wall antigen, cysteine rich domain NW1
20070 citationsauthor #3
Structure of NOWA cysteine rich domain 6
20070 citationsauthor #8
Nematocyst Outer Wall Antigen, NW1 K21P
20070 citationsauthor #3
Ultra high resolution backbone conformation of protein GB1 from residual dipolar couplings alone
20070 citationsauthor #3
1H, 13C, and 15N chemical shift assignments for the N-terminal extracellular domain of T-cadherin
20071 citationsauthor #5
Continuous molecular evolution of protein-domain structures by single amino acid changes.
200763 citationsauthor #6
Direct observation of dipolar couplings and hydrogen bonds across a beta-hairpin in 8 M urea.
200756 citationsauthor #4
Structure of the non-canonical Mcol5 of Hydra nematocysts
20070 citationsauthor #3
Sequence-structure and structure-function analysis in cysteine-rich domains forming the ultrastable nematocyst wall.
200728 citationsauthor #8
Nematocyst outer wall antigen, NW1 G11V K21P
20070 citationsauthor #3
Recognition of RANTES by extracellular parts of the CCR5 receptor.
2007101 citationsauthor #5
Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb
200758 citationsauthor #6
DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus
2007224 citationsauthor #6
NW1, K21P, Structural Species II
20070 citationsauthor #3
Mapping the conformational landscape of urea-denatured ubiquitin using residual dipolar couplings.
200773 citationsauthor #2
Correlation of protein structure and dynamics to scalar couplings across hydrogen bonds.
200730 citationsauthor #3
Structure of NOWA cysteine rich domain 8
20070 citationsauthor #8
Ultrahigh-resolution backbone structure of perdeuterated protein GB1 using residual dipolar couplings from two alignment media.
200635 citationsauthor #3

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