I. Shureiqi

PPARδ: An Underappreciated Tumor Accelerator in Pancreatic Ductal Adenocarcinoma.
20260 citationsauthor #5
Colorectal 15-Lipoxygenase-1 as a Host Factor Determining the Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Colorectal Tumorigenesis in Mice
20250 citationsauthor #11
EPA, DHA, and resolvin effects on cancer risk: the underexplored mechanisms.
20247 citationsauthor #5
Abstract 2182: 15-lipoxygenase-1 modulation of colonic resolvin production to suppress colorectal carcinogenesis
20240 citationsauthor #7
Abstract 3038: PPARδ promotes gastric adenocarcinoma carcinogenesis by enhancing ZBP1-induced necroptosis and inflammation and fostering gastric tumor immunosuppressive microenvironment
20240 citationsauthor #5
Dysregulated KLF4 expression plays a pivotal role in the pathogenesis of pancreatic intraductal papillary mucinous neoplasms
20245 citationsauthor #10
Colorectal ALOX15 as a host factor determinant of EPA and DHA effects on colorectal carcinogenesis
20243 citationsauthor #11
PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment
202317 citationsauthor #14
Association of Prediagnosis Obesity and Postdiagnosis Aspirin With Survival From Stage IV Colorectal Cancer
20223 citationsauthor #19
Aspirin for Colorectal Cancer Prevention: Age Matters.
20223 citationsauthor #1
Abstract A023: Influence of pre-diagnosis obesity and post-diagnosis aspirin use on survival from stage IV colorectal cancer
20220 citationsauthor #19
Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ
202258 citationsauthor #19
Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors
20229 citationsauthor #6
deepOrganoid: A brightfield cell viability model for screening matrix-embedded organoids.
202225 citationsauthor #7
Epigenome-Wide Study Identifies Epigenetic Outliers in Normal Mucosa of Patients with Colorectal Cancer
20226 citationsauthor #6
Abstract 3821: Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARD
20220 citationsauthor #19
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation
202226 citationsauthor #8
Abstract 6265: Do epigenetic outliers impact racial disparities in colorectal cancer
20220 citationsauthor #5
BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation
20220 citationsauthor #8
Use of Uridine Triacetate to Reverse Severe Persistent Myelosuppression Following 5-fluorouracil Exposure in a Patient With a c.557A>G Heterozygous DPYD Variant.
202110 citationsauthor #3
A rat model to investigate quality of recovery after abdominal surgery
20217 citationsauthor #10
Ppard Is Essential in Acceleration of Pancreatic Ductal Adenocarcinoma Development by High-Fat Diet in Mutant Kras Mice
20201 citationsauthor #15
A phase II study of durvalumab (MEDI4736) (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
20202 citationsauthor #11
FOLFOXIRI Versus Doublet Regimens in Right-Sided Metastatic Colorectal Cancer: Focus on Subsequent Therapies and Impact on Overall Survival.
20205 citationsauthor #5
A randomized study evaluating tailoring of advanced/metastatic colorectal cancer (mCRC) therapy using circulating cell-free tumor DNA (ctDNA) (TACT-D).
20202 citationsauthor #10
Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P.
202025 citationsauthor #16
Clinical and pathologic factors associated with survival in BRAFV600E colorectal cancers.
20202 citationsauthor #7
Celecoxib Colorectal Bioavailability and Chemopreventive Response in Familial Adenomatous Polyposis Patients
20200 citationsauthor #7
Abstract 2557: 15-lipoxygenase-1 suppresses linoleic acid promotion of colorectal tumorigenesis through oxidative metabolism of PI3P_linoleic acid to inhibit membranous LRP5 recycling and WNT/β-catenin signaling activation
20200 citationsauthor #16
PPARD and Interferon Gamma Promote Transformation of Gastric Progenitor Cells and Tumorigenesis in Mice.
201944 citationsauthor #25
Pleiotropic Effects of PPARD Accelerate Colorectal Tumorigenesis, Progression, and Invasion.
201952 citationsauthor #18
Patient-reported Symptom Outcomes and Microsatellite Instability in Patients With Metastatic Colorectal Cancer.
20192 citationsauthor #7
FOLFOXIRI versus doublet-regimens in the first-line therapy of MSI-S right-sided (RS) metastatic colorectal cancer (mCRC): A survival analysis.
20190 citationsauthor #4
Meat consumption and BRAF mutation status in colorectal cancer.
20190 citationsauthor #9
Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma
20198 citationsauthor #9
Suppression of membranous LRP5 recycling, WNT/β-catenin signaling, and colorectal tumorigenesis by 15-LOX-1 peroxidation of PI3P_linoleic acid
20190 citationsauthor #16
The association between female hormonal supplementation and molecular types in colorectal cancer.
20190 citationsauthor #8
Abstract 2599: Pleiotropic effects of PPARD accelerate colorectal tumorigenesis progression and invasion
20190 citationsauthor #18
Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion
20181 citationsauthor #17
Novel and emerging innate immune therapeutic targets for pancreatic cancer
20186 citationsauthor #2
The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor
2018150 citationsauthor #6
Oxygenated lipid signaling in tumor-associated macrophages—focus on colon cancer
201813 citationsauthor #4
Predictors for detecting circulating tumor DNA (ctDNA) in metastatic colorectal cancer (mCRC).
20180 citationsauthor #11
Clinical utility of circulating cell-free DNA in advanced colorectal cancer
201725 citationsauthor #7
ALOX15 as a suppressor of inflammation and cancer: Lost in the link.
201766 citationsauthor #6
Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma
201741 citationsauthor #9
Metastasis regulation by PPARD expression in cancer cells.
201768 citationsauthor #19
FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma
201768 citationsauthor #8
Abstract 2224: Increased 15-lipoxygenase-1 activity limits tumor development in the azoxymethane mouse model of colon cancer: impact of omega-3-acid ethyl esters
20170 citationsauthor #10
PPARD regulation in gastric progenitor cells drives gastric tumorigenesis in mice
20170 citationsauthor #18
Abstract 844: PPARD downregulation in cancer cells suppresses metastases by inhibiting tumor angiogenesis and EMT
20170 citationsauthor #10
Molecular Predicators of Duodenal Familial Adenomatous Polyposis Chemoprevention: Do Chemopreventive Drugs Hit Their Presumed Molecular Targets?
20170 citationsauthor #1
Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer
201783 citationsauthor #11
Can an Organoid Recapitulate the Metabolome of its Parent Tissue? A Pilot NMR Spectroscopy Study
201711 citationsauthor #9
The role of 15-lipoxygenase-1 expression and its potential role in the pathogenesis of endometrial hyperplasia and endometrial adenocarcinomas.
20165 citationsauthor #6
Abstract 3819: PPAR-delta promotes Wnt/B-catenin-driven colorectal tumorigenesis
20160 citationsauthor #7
Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials.
201630 citationsauthor #13
Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation.
2016187 citationsauthor #14
methylation and KRAS signaling FXR silencing in human colon cancer by DNA
20160 citationsauthor #8
Abstract 1959: 15-lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway
20150 citationsauthor #10
Clinical utility of a circulating cell-free DNA assay for clinical trial enrollment in refractory metastatic colorectal cancer patients.
20150 citationsauthor #8
Proteomic signatures of colorectal cancer to identify distinct and reproducible subgroups and to reflect prognosis.
20150 citationsauthor #11
Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancer
201543 citationsauthor #8
Abstract 5236: Prospective clinical application of circulating cell-free DNA sequencing in metastatic colorectal cancer
20150 citationsauthor #6
Proteomic signatures of colorectal cancer to identify distinct and reproducible subgroups independent of oncogenic mutations.
20150 citationsauthor #11
Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-like and Claudin-Low Breast Cancer
201522 citationsauthor #9
Phase Ib study of vemurafenib in combination with irinotecan and cetuximab in patients with BRAF-mutated metastatic colorectal cancer and advanced cancers.
201537 citationsauthor #13
Predictors of clonal evolution in metastatic colorectal cancer patients.
20151 citationsauthor #9
15‐Lipoxygenase‐1 suppression of colitis‐associated colon cancer through inhibition of the IL‐6/STAT3 signaling pathway
201538 citationsauthor #10
A Case Report—Treatment of Metastatic Colorectal Cancer in a Patient on Hemodialysis
20143 citationsauthor #3
Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal cancer: a phase 1 trial.
201417 citationsauthor #12
Potentiation of colon cancer susceptibility in mice by colonic epithelial PPAR-δ/β overexpression.
201449 citationsauthor #12
Association of CpG island methylator phenotype (CIMP) with inferior progression-free survival with anti-EGFR monoclonal antibody therapy in metastatic colorectal cancer.
20143 citationsauthor #12
Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
2014423 citationsauthor #11
Clinical Investigation : Gastrointestinal Cancer Preoperative Radiation Therapy With Concurrent Capecitabine , Bevacizumab , and Erlotinib for Rectal Cancer : A Phase 1 Trial
20140 citationsauthor #12
Cellular location and expression of Na+, K+‐ATPase α subunits affect the anti‐proliferative activity of oleandrin
201436 citationsauthor #8
15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells
201421 citationsauthor #7
Phase 1B study of vemurafenib in combination with irinotecan and cetuximab in patients with BRAF-mutated advanced cancers and metastatic colorectal cancer.
201429 citationsauthor #10
FXR silencing in human colon cancer by DNA methylation and KRAS signaling.
201483 citationsauthor #4
Frequency of concurrent gene mutations and copy number alterations in circulating cell-free DNA (cfDNA) from refractory metastatic CRC patients.
20147 citationsauthor #5
Mutation and copy number discordance in primary versus metastatic colorectal cancer (mCRC).
201419 citationsauthor #11
Abstract 122: 15-lipoxygenase-1 regulation of HIF-1a and angiogenesis
20140 citationsauthor #6
Efficiency of biomarker screening for enriched metastatic colorectal cancer trials: The ATTACC program experience.
20140 citationsauthor #13
cancer metastatic progression and chromosomal instability in colon , a novel noncoding RNA mapping to 8 q 24 , underlies CCAT 2 Material Supplemental
20130 citationsauthor #26
Global quantitative assessment of the colorectal polyp burden in familial adenomatous polyposis by using a web-based tool.
20139 citationsauthor #10
Abstract 3561: Silencing of farnesoid X receptor in human colon cancer by epigenetic mechanisms is associated with cancer progression.
20130 citationsauthor #5
Eicosanoid profiling in colon cancer: emergence of a pattern.
201324 citationsauthor #2
Targeting peroxisome proliferator-activated receptor-β/δ in colon cancer: how to aim?
201320 citationsauthor #3
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer
2013610 citationsauthor #26
Su1298 QVAPolyp: Quantitative, Video-Based Assessment of Celecoxib Effects on Colorectal Polyp Burden in Familial Adenomatous Polyposis Using Web-Based Tool
20120 citationsauthor #9
Preoperative radiation therapy with concurrent capecitabine, bevacizumab, and erlotinib for rectal adenocarcinoma: A phase I trial.
20121 citationsauthor #11
Effects of gut-targeted 15-LOX-1 transgene expression on colonic tumorigenesis in mice.
201243 citationsauthor #11
Arachidonic acid metabolism in human prostate cancer
201274 citationsauthor #6
15-Lipoxygenase-1 as a tumor suppressor gene in colon cancer: is the verdict in?
201161 citationsauthor #3
Curcumin Chemoprevention: The Long Road to Clinical Translation
201143 citationsauthor #1
Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion
201144 citationsauthor #11
Profiling Lipoxygenase Metabolism in Specific Steps of Colorectal Tumorigenesis
201063 citationsauthor #1
Abstract 2897: Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis
20100 citationsauthor #1
15-LOX-1 transcription suppression through the NuRD complex in colon cancer cells
200926 citationsauthor #4
Targeted genetic disruption of peroxisome proliferator-activated receptor-delta and colonic tumorigenesis.
200983 citationsauthor #7

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