David R. Loiselle

PROFILE

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Aliases
David Loiselle, David R Loiselle, David r. Loiselle
Publication record
41 papers · 1,673 citations · H-index 23

PAPERS

Expression of membrane Hsp90 is a molecular signature of T cell activation
20229 citationsauthor #8
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
202130 citationsauthor #9
Expression of extracellular Hsp90 is a molecular signature of T cell activation, providing a means to image and target T Cell activation in autoimmune disease
20210 citationsauthor #8
Transcription factor–driven alternative localization of Cryptococcus neoformans superoxide dismutase
202111 citationsauthor #4
A bioorthogonal chemical reporter for fatty acid synthase–dependent protein acylation
202113 citationsauthor #3
Author response: Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death
20200 citationsauthor #4
Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1
202070 citationsauthor #4
Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death
202030 citationsauthor #4
Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion
20198 citationsauthor #9
Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90
201946 citationsauthor #7
Genetic and pharmacological validation of TAK1 inhibition in macrophages as a therapeutic strategy to effectively inhibit TNF secretion
201831 citationsauthor #6
Cellular fatty acid synthase is required for late stages of HIV-1 replication
201745 citationsauthor #7
Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer.
201724 citationsauthor #5
Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
2017118 citationsauthor #7
A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo.
201747 citationsauthor #7
An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target.
201647 citationsauthor #4
Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.
2016134 citationsauthor #3
Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.
201626 citationsauthor #4
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
201675 citationsauthor #5
Abstract 4457: Novel fatty-acid synthase inhibitor in combination with platinum-based therapy provides increased tumor killing efficacy in luminal breast murine model
20150 citationsauthor #4
Pregnancy and Smoothelin-like Protein 1 (SMTNL1) Deletion Promote the Switching of Skeletal Muscle to a Glycolytic Phenotype in Human and Mice*
201519 citationsauthor #5
c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells
201566 citationsauthor #8
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70.
201465 citationsauthor #6
Identiﬁcation of an Allosteric Small-Molecule Inhibitor Selective for the Inducible Form of Heat Shock Protein 70
20145 citationsauthor #6
Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
201363 citationsauthor #6
The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules
2013184 citationsauthor #3
Tethered Hsp90 Inhibitors Carrying Optical or Radioiodinated Probes Reveal Selective Internalization of Ectopic Hsp90 in Malignant Breast Tumor Cells
20131 citationsauthor #6
Author ' s personal copy A highly selective Hsp 90 affinity chromatography resin with a cleavable linker
20120 citationsauthor #4
A highly selective Hsp90 affinity chromatography resin with a cleavable linker.
201228 citationsauthor #4
Smoothelin-like 1 Protein Is a Bifunctional Regulator of the Progesterone Receptor during Pregnancy*
201123 citationsauthor #5
Efficient detection of RNA–protein interactions using tethered RNAs
201181 citationsauthor #2
Smoothelin-like 1 Protein Regulates Myosin Phosphatase-targeting Subunit 1 Expression during Sexual Development and Pregnancy*
201038 citationsauthor #4
Human Cytidine Triphosphate Synthetase 1 Interacting Proteins
200813 citationsauthor #2
ROCK1 Phosphorylates and Activates Zipper-interacting Protein Kinase*
200791 citationsauthor #6
Abstract 329: Discovery of a Novel Paracrine Angiogenic Factor from Akt-Transduced Mesenchymal Stem Cells for Cell/Protein-based Therapy in angiogenesis
20070 citationsauthor #6
Abstract 1120: Akt Modified MSCs Secrete a Novel Stem Cell Paracrine Factor that Protects Injured Heart, Activates Cyclin Dependent Kinase and Phosphorylates/Activates Akt Signaling Pathway in Adult Rat Cardiomyocytes
20070 citationsauthor #6
Identification of components of protein complexes.
200545 citationsauthor #3
Improved protein identification through the use of unstained gels.
20057 citationsauthor #1
Selective roles for TACE / ADAM 17 in the shedding of the epidermal growth factor receptor ligand family . The juxtamembrane stalk determines cleavage efficiency . *
200410 citationsauthor #3
Selective Roles for Tumor Necrosis Factor α-converting Enzyme/ADAM17 in the Shedding of the Epidermal Growth Factor Receptor Ligand Family
200417 citationsauthor #3
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.
2004154 citationsauthor #3

TIMELINE

2004 181 citations

2005 52 citations

2007 91 citations

2008 13 citations

2010 38 citations

2011 104 citations

2012 28 citations

2013 248 citations

2014 70 citations

2015 85 citations

2016 282 citations

2017 234 citations

2018 31 citations

2019 54 citations

2020 100 citations

2021 54 citations

2022 9 citations

David R. Loiselle

PROFILE

PAPERS

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