Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Biochemistry

• Publication date

  2016-08-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1021/acs.biochem.6b00489PMID 27509380PMCID PMC5513659
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progressive rod-cone degeneration (PRCD) in selected dog breeds and variability in its phenotypic expression.

  2018cited by this paper
• Impact of whole exome sequencing among Iranian patients with autosomal recessive retinitis pigmentosa.

  2015cited by this paper
• The physiology of protein S-acylation.

  2015cited by this paper
• Real-time PCR genotyping assay for canine progressive rod-cone degeneration and mutant allele frequency in Toy Poodles, Chihuahuas and Miniature Dachshunds in Japan

  2015cited by this paper
• Guanylate cyclase 1 relies on rhodopsin for intracellular stability and ciliary trafficking

  2015cited by this paper
• The progressive rod-cone degeneration (PRCD) protein is secreted through the conventional ER/Golgi-dependent pathway.

  2014cited by this paper
• Molecular complexes that direct rhodopsin transport to primary cilia.

  2014cited by this paper
• Next-generation sequencing-based molecular diagnosis of a Chinese patient cohort with autosomal recessive retinitis pigmentosa.

  2013cited by this paper
• Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.

  2013cited by this paper
• Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration

  2013cited by this paper
• Protein sorting, targeting and trafficking in photoreceptor cells.

  2013cited by this paper
• Identification of a novel mutation in the PRCD gene causing autosomal recessive retinitis pigmentosa in a Turkish family

  2013cited by this paper
• Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection.

  2013cited by this paper
• Membrane Attachment Is Key to Protecting Transducin GTPase-Activating Complex from Intracellular Proteolysis in Photoreceptors

  2011cited by this paper
• Site-specific analysis of protein S-acylation by resin-assisted capture[S]

  2011cited by this paper
• Identification of a prevalent founder mutation in an Israeli Muslim Arab village confirms the role of PRCD in the aetiology of retinitis pigmentosa in humans

  2010cited by this paper
• Proteomic Profiling of a Layered Tissue Reveals Unique Glycolytic Specializations of Photoreceptor Cells*

  2010cited by this paper
• Real-Time Detection of the Mutation Responsible for Progressive Rod-Cone Degeneration in Labrador Retriever Dogs Using Locked Nucleic Acid TaqMan Probes

  2009cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation.

  2009cited by this paper
• Depleting Rac1 in mouse rod photoreceptors protects them from photo-oxidative stress without affecting their structure or function

  2009cited by this paper
• The outer segment serves as a default destination for the trafficking of membrane proteins in photoreceptors

  2008cited by this paper
• Loss of Neuroprotective Survival Signal in Mice Lacking Insulin Receptor Gene in Rod Photoreceptor Cells*

  2008cited by this paper
• Transducin Translocation in Rods Is Triggered by Saturation of the GTPase-Activating Complex

  2007cited by this paper
• Palmitoylated proteins: purification and identification

  2007cited by this paper
• The pool of fatty acids covalently bound to platelet proteins by thioester linkages can be altered by exogenously supplied fatty acids

  2007cited by this paper
• Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals.

  2006cited by this paper
• Identical mutation in a novel retinal gene causes progressive rod-cone degeneration in dogs and retinitis pigmentosa in humans.

  2006cited by this paper
• Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome.

  2006cited by this paper
• Morphological and Biochemical Studies of Canine Progressive Rod-Cone Degeneration 3 H-Fucose Aurorodiogrophy

  2005cited by this paper
• Electroporation and RNA interference in the rodent retina in vivo and in vitro

  2003cited by this paper
• Light-mediated activation of Rac-1 in photoreceptor outer segments.

  2003cited by this paper
• Transmembrane domain length determines intracellular membrane compartment localization of syntaxins 3, 4, and 5.

  2001cited by this paper
• Morphological, physiological, and biochemical changes in rhodopsin knockout mice.

  1999cited by this paper
• ‘Shocking’ developments in chick embryology: electroporation and in ovo gene expression

  1999cited by this paper
• Modulation of class I major histocompatibility complex antigen cell-surface stability by transmembrane domain length variation.

  1997cited by this paper
• Decreased opsin mRNA and immunoreactivity in progressive rod-cone degeneration (prcd): cytochemical studies of early disease and degeneration.

  1994cited by this paper
• Rhodopsin levels in the central retinas of normal miniature poodles and those with progressive rod-cone degeneration.

  1992cited by this paper
• Variation in retinal degeneration phenotype inherited at the prcd locus.

  1988cited by this paper
• Nomarski evaluation of rod outer segment renewal in a hereditary retinal degeneration. Comparison with autoradiographic evaluation.

  1987cited by this paper
• Morphological and biochemical studies of canine progressive rod-cone degeneration. 3H-fucose autoradiography.

  1986cited by this paper
• Progressive rod-cone degeneration in the dog: characterization of the visual pigment.

  1982cited by this paper
• Pathogenesis of progressive rod-cone degeneration in miniature poodles.

  1982cited by this paper
• Proteinase K from Tritirachium album Limber.

  1974cited by this paper
• Progressive retinal atrophy in the miniature poodle: an electrophysiologic study.

  1972cited by this paper

• The tetraspanin disc proteins, peripherin-2 and ROM1, facilitate CNG channel localization to the rod outer segment

  2025cites this paper
• Novel progressive rod-cone degeneration mutation causes retinitis pigmentosa.

  2025cites this paper
• Extracellular vesicles highlight many cases of photoreceptor degeneration

  2023cites this paper
• ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims

  2023cites this paper
• Absence of PRCD Leads to Dysregulation in Lipid Homeostasis Resulting in Disorganization of Photoreceptor Outer Segment Structure.

  2023cites this paper
• R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization

  2022influential citation
• Dual Palmitoylation of PRCD, a Photoreceptor-Specific Protein Linked to RP, Alters Protein Stability and Subcellular Localization

  2022influential citation
• On the Wrong Track: Alterations of Ciliary Transport in Inherited Retinal Dystrophies

  2021cites this paper
• Photoreceptor Disc Enclosure Is Tightly Controlled by Peripherin-2 Oligomerization

  2021cites this paper
• Compartmentalization of Photoreceptor Sensory Cilia

  2021cites this paper
• The GARP Domain of the Rod CNG Channel ’ s b 1-Subunit Contains Distinct Sites for Outer Segment Targeting and Connecting to the Photoreceptor Disk Rim

  2021cites this paper
• Functional compartmentalization of photoreceptor neurons

  2021cites this paper
• The GARP Domain of the Rod CNG Channel's β1-Subunit Contains Distinct Sites for Outer Segment Targeting and Connecting to the Photoreceptor Disk Rim

  2020cites this paper
• Large Animal Models of Inherited Retinal Degenerations: A Review

  2020cites this paper
• Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

  2020cites this paper
• The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice

  2020cites this paper
• Photoreceptor Discs: Built Like Ectosomes.

  2020cites this paper
• Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes

  2020cites this paper
• TULP1 and TUB Are Required for Specific Localization of PRCD to Photoreceptor Outer Segments

  2020influential citation
• PRCD is essential for high-fidelity photoreceptor disc formation

  2019cites this paper
• PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function.

  2019cites this paper
• Photoreceptor disc membranes are formed through an Arp2/3-dependent lamellipodium-like mechanism

  2019cites this paper
• EARLY VITAMIN A SUPPLEMENTATION IMPROVES THE OUTCOME OF RETINOPATHY OF PREMATURITY IN EXTREMELY PRETERM INFANTS

  2019cites this paper
• PRCD is Concentrated at the Base of Photoreceptor Outer Segments and is Involved in Outer Segment Disc Formation.

  2019cites this paper
• Functional Genomics of the Retina to Elucidate its Construction and Deconstruction

  2019cites this paper
• Protein Sorting in Healthy and Diseased Photoreceptors.

  2019cites this paper
• Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina

  2018cites this paper
• Cilia - The sensory antennae in the eye.

  2017cites this paper
• The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking

  2017cites this paper