H. Schüler

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
202354 citationsauthor #10
PARP14 is a writer, reader, and eraser of mono-ADP-ribosylation
202324 citationsauthor #4
Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors.
20228 citationsauthor #5
14-3-3 Activated Bacterial Exotoxins AexT and ExoT Share Actin and the SH2 Domains of CRK Proteins as Targets for ADP-Ribosylation
20222 citationsauthor #7
MacroGreen, a simple tool for detection of ADP-ribosylated proteins
202117 citationsauthor #4
Correction to "A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes".
20213 citationsauthor #9
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates
20212 citationsauthor #17
MacroGreen, a simple tool for detection of ADP-ribosylated proteins
20210 citationsauthor #4
System-wide identification and prioritization of enzyme substrates by thermal analysis
202153 citationsauthor #17
PARP10 Multi-Site Auto- and Histone MARylation Visualized by Acid-Urea Gel Electrophoresis
202110 citationsauthor #2
Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins
202073 citationsauthor #11
System-wide identification and prioritization of enzyme substrates by thermal analysis (SIESTA)
20201 citationsauthor #17
Human PARP16 (ARTD15) IN COMPLEX WITH EB-47
20190 citationsauthor #4
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000633a
20190 citationsauthor #8
Correction to "Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors".
20192 citationsauthor #9
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000711a
20190 citationsauthor #8
Crystal structure of in vitro evolved Af1521
20190 citationsauthor #5
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000347a
20190 citationsauthor #8
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000466a
20190 citationsauthor #8
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000597a
20191 citationsauthor #8
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000385a
20190 citationsauthor #8
Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD
20190 citationsauthor #4
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000506a
20190 citationsauthor #8
A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.
201977 citationsauthor #9
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000242a
20190 citationsauthor #8
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000475a
20190 citationsauthor #8
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000110a
20190 citationsauthor #8
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000352a
20190 citationsauthor #8
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000299a
20190 citationsauthor #8
Human PARP1 (ARTD1) - Catalytic domain in complex with inhibitor ME0527
20190 citationsauthor #9
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000462a
20190 citationsauthor #8
Human PARP10 (ARTD10), catalytic fragment in complex with 3-aminobenzamide and citrate
20190 citationsauthor #3
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000278a
20190 citationsauthor #8
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000605a
20190 citationsauthor #8
PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000065a
20190 citationsauthor #8
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMSOA000341b
20190 citationsauthor #8
Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form
20180 citationsauthor #6
Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14.
201836 citationsauthor #9
Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form in complex with STO1101
20180 citationsauthor #6
Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol
201823 citationsauthor #6
Cover Feature: A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition (ChemMedChem 13/2018)
20180 citationsauthor #9
Structure-activity relationships for inhibitors of Pseudomonas aeruginosa exoenzyme S ADP-ribosyltransferase activity.
201813 citationsauthor #7
System-wide Identification of Enzyme Substrates by Thermal Analysis (SIESTA)
20187 citationsauthor #15
Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form
20180 citationsauthor #5
Yersinia YscU C-terminal fragment in complex with a synthetic compound
20180 citationsauthor #7
14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface
201841 citationsauthor #17
A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity.
201857 citationsauthor #9
A DNA‐Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition
201844 citationsauthor #9
Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101
20180 citationsauthor #6
Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, trimeric crystal form bound to Carba-NAD
20180 citationsauthor #6
Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14.
201723 citationsauthor #10
Human PARP14 (ARTD8), catalytic fragment in complex with an N-aryl piperazine inhibitor
20170 citationsauthor #3
Targeting dissociation of the substrate specificity switch protein YscU in the Yersinia type III secretion system with small molecules
20170 citationsauthor #9
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.
2017310 citationsauthor #9
Selectivity profile of the poly(ADP-ribose) polymerase (PARP) inhibitor, A-966492
20173 citationsauthor #2
Human PARP10 (ARTD10), catalytic fragment in complex with PARP inhibitor Veliparib
20170 citationsauthor #3
Small Molecule Microarray Based Discovery of PARP14 Inhibitors.
201749 citationsauthor #4
Sister Chromatid Cohesion Establishment Factor ESCO1 Operates by Substrate-Assisted Catalysis.
201610 citationsauthor #8
Sirtuins are Unaffected by PARP Inhibitors Containing Planar Nicotinamide Bioisosteres
201618 citationsauthor #2
Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor MCD72
20160 citationsauthor #6
Identification of Inhibitors of Pseudomonas aeruginosa Exotoxin-S ADP-Ribosyltransferase Activity
201613 citationsauthor #6
DNA binding to SMC ATPases—trapped for release
20165 citationsauthor #1
Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library.
201554 citationsauthor #13
Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library.
201586 citationsauthor #13
Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor ME0328
20150 citationsauthor #10
Towards small molecule inhibitors of mono-ADP-ribosyltransferases.
201547 citationsauthor #9
Human PARP13 (ZC3HAV1), C-Terminal PARP Domain (H810N; N830Y variant)
20150 citationsauthor #4
Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.
201517 citationsauthor #2
HUMAN ARTD1 (PARP1) - CATALYTIC DOMAIN IN COMPLEX WITH INHIBITOR TALAZOPARIB
20151 citationsauthor #8
HUMAN ARTD2 (PARP2) - CATALYTIC DOMAIN IN COMPLEX WITH OLAPARIB
20150 citationsauthor #5
Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein*
201575 citationsauthor #9
Human ESCO1 (Eco1/Ctf7 ortholog), acetyltransferase domain in complex with acetyl-CoA
20150 citationsauthor #30
Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein*
201575 citationsauthor #8
Design, synthesis, crystallographic studies, and preliminary biological appraisal of new substituted triazolo[4,3-b]pyridazin-8-amine derivatives as tankyrase inhibitors.
201432 citationsauthor #9
Crystal structure of OCRL in complex with a phosphate ion
20140 citationsauthor #12
Human artd3 (parp3) - catalytic domain in complex with inhibitor STO1542
20140 citationsauthor #10
Human artd3 (parp3) - catalytic domain in complex with inhibitor ME0400
20140 citationsauthor #10
Human artd3 (parp3) - catalytic domain in complex with inhibitor STO1168
20140 citationsauthor #10
Crystal Structure of INPP5B in complex with Phosphatidylinositol 3,4- bisphosphate
20140 citationsauthor #12
Human artd3 (parp3) - catalytic domain in complex with inhibitor ME0395
20140 citationsauthor #10
Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling
201371 citationsauthor #4
Pharmacology of ADP‐ribosylation
20133 citationsauthor #1
Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
20130 citationsauthor #8
Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3.
201312 citationsauthor #11
PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
201355 citationsauthor #13
Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
2013132 citationsauthor #13
PARP inhibitors: polypharmacology versus selective inhibition
201369 citationsauthor #3
Human PARP14 (ARTD8, BAL2) - macro domains 1 and 2 in complex with adenosine-5-diphosphoribose
20130 citationsauthor #8
BRICHOS domain of Surfactant protein C precursor protein
20120 citationsauthor #36
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
2012473 citationsauthor #14
Human Artd8 (Parp14, Bal2) - catalytic domain in complex with inhibitor A16(Z)
20120 citationsauthor #10
Human Mitochondrial endo-exonuclease
20121 citationsauthor #16
Human ARTD15/PARP16 IN COMPLEX WITH 3-AMINOBENZAMIDE
20120 citationsauthor #4
HUMAN PARP14 (ARTD8, BAL2) - MACRO DOMAIN 3
20120 citationsauthor #9
Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase
201231 citationsauthor #9
Discovery of ligands for ADP-ribosyltransferases via docking-based virtual screening.
201243 citationsauthor #12
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.
20120 citationsauthor #4
Human Artd8 (Parp14, Bal2) - catalytic domain in complex with A16(E)
20120 citationsauthor #10
Crystal structure of human SHIP2 in complex with biphenyl 2,3',4,5',6- pentakisphosphate
20120 citationsauthor #14
Human ADP-RIBOSYLTRANSFERASE 7 (ARTD7/PARP15), CATALYTIC DOMAIN IN COMPLEX WITH STO1102
20120 citationsauthor #10

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