J. Coers

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Aliases
J Coers, Jörn Coers, J. Coers, Jorn Coers, Jörn Coers
Publication record
97 papers · 6,409 citations · H-index 41

PAPERS

Human giant GTPase GVIN1 forms an antimicrobial coatomer around the intracellular bacterial pathogen Burkholderia thailandensis
20251 citationsauthor #6
Guanylate-Binding Proteins Promote Host Defense Against Leishmania major by Balancing iNOS/Arg-1 in Myeloid Cells
20250 citationsauthor #9
Autophagy and Bacterial infections
20254 citationsauthor #5
The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
20250 citationsauthor #9
Type I interferon signaling and peroxisomal dysfunction contribute to enhanced inflammatory cytokine production in IRGM1-deficient macrophages
20243 citationsauthor #15
Restriction and evasion: a review of IFNγ-mediated cell-autonomous defense pathways during genital Chlamydia infection
20245 citationsauthor #2
The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
20241 citationsauthor #8
Irgm proteins attenuate inflammatory disease in mouse models of genital Chlamydia infection
20244 citationsauthor #7
The Shigella flexneri effector IpaH1.4 facilitates RNF213 degradation and protects cytosolic bacteria against interferon-induced ubiquitylation
20246 citationsauthor #9
LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro
202354 citationsauthor #9
Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation
202315 citationsauthor #7
A binary module for microbiota-mediated regulation of γδ17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1.
20232 citationsauthor #12
Pyroptosis in defense against intracellular bacteria.
202344 citationsauthor #3
Overexpression of T3SS translocation signals in Salmonella causes delayed attenuation
20231 citationsauthor #6
An aging-susceptible circadian rhythm controls cutaneous antiviral immunity
202312 citationsauthor #11
A binary module for microbiota-mediated regulation of γδ17 cells, hallmarked by microbiota-driven expression of programmed cell death protein 1
20233 citationsauthor #12
The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
20238 citationsauthor #8
An ancestral mycobacterial effector promotes dissemination of infection.
202241 citationsauthor #11
GBP2 aggregates LPS and activates the caspase-4 inflammasome independent of the bacterial encapsulation factor GBP1
20222 citationsauthor #9
Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous Vacuoles
202235 citationsauthor #5
How did we get here? Insights into mechanisms of immunity-related GTPase targeting to intracellular pathogens.
202217 citationsauthor #2
Interactions of Autophagy and the Immune System in Health and Diseases
202220 citationsauthor #12
Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation
202224 citationsauthor #7
Irgm proteins attenuate inflammatory disease in mouse models of genital Chlamydia infection
20223 citationsauthor #4
Caspase-11 Interaction with NLRP3 Potentiates the Noncanonical Activation of the NLRP3 Inflammasome
202283 citationsauthor #9
Differential Requirement for IRGM Proteins during Tuberculosis Infection in Mice
202212 citationsauthor #5
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction.
202244 citationsauthor #13
Can't live outside you: a thematic issue on obligate intracellular bacterial pathogens.
20210 citationsauthor #1
SNX10 and caspase‐5 sort out endosomal LPS for a gut‐wrenching Slug‐fest
20212 citationsauthor #2
Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii
202113 citationsauthor #4
IRF3 inhibits IFN‐γ‐mediated restriction of intracellular pathogens in macrophages independently of IFNAR
20218 citationsauthor #5
The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.
20219 citationsauthor #4
Immunopathogenesis of genital Chlamydia infection: insights from mouse models.
202135 citationsauthor #2
Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting
202020 citationsauthor #4
Human guanylate binding proteins: nanomachines orchestrating host defense
202070 citationsauthor #2
Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions
2020134 citationsauthor #6
Mycobacterium tuberculosis Evasion of Guanylate Binding Protein-Mediated Host Defense in Mice Requires the ESX1 Secretion System
202012 citationsauthor #4
Dynamin-related Irgm proteins modulate LPS-induced caspase-4 activation and septic shock
202047 citationsauthor #13
C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo
201913 citationsauthor #7
IRG1 and iNOS act redundantly with other interferon gamma-induced factors to restrict intracellular replication of Legionella pneumophila
20190 citationsauthor #7
Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture
201928 citationsauthor #10
A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins
201920 citationsauthor #5
Fresh faces and new approaches at Pathogens and Disease.
20190 citationsauthor #2
IRG1 and Inducible Nitric Oxide Synthase Act Redundantly with Other Interferon-Gamma-Induced Factors To Restrict Intracellular Replication of Legionella pneumophila
201937 citationsauthor #7
Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.
201924 citationsauthor #6
Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense.
201825 citationsauthor #1
Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses
201878 citationsauthor #6
IRF3 inhibits IFNγ-mediated restriction of intracellular pathogens in macrophages independently of type I interferons
20180 citationsauthor #4
PLOS Pathogens 2017 Reviewer and Editorial Board Thank You
20180 citationsauthor #37
Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems
2017135 citationsauthor #9
Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components
201738 citationsauthor #8
Sweet host revenge: Galectins and GBPs join forces at broken membranes
201723 citationsauthor #1
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
2017130 citationsauthor #9
Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages*
201727 citationsauthor #8
Metabolic changes in Irgm 1-deficient macrophages 1 Metabolic alterations contribute to enhanced inflammatory cytokine production in Irgm 1-deficient macrophages
20170 citationsauthor #8
The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs.
2017111 citationsauthor #7
Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility
2017107 citationsauthor #9
Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases.
201787 citationsauthor #13
Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii
201672 citationsauthor #6
The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence
201662 citationsauthor #9
Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.
201615 citationsauthor #2
Sensing the enemy, containing the threat: cell-autonomous immunity to Chlamydia trachomatis.
201650 citationsauthor #2
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
201650 citationsauthor #377
Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells
201652 citationsauthor #9
Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease.
2016192 citationsauthor #4
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
20161,464 citationsauthor #369
Canonical Inflammasomes Drive IFN-g to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium Graphical
2015107 citationsauthor #6
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins
2015158 citationsauthor #9
Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii
201517 citationsauthor #1
ID: 260: Ubiquitination of pathogen-containing vacuoles triggers host defense by IFN-inducible GBPs
20151 citationsauthor #1
Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages
2015135 citationsauthor #10
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
2014329 citationsauthor #10
The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance
201486 citationsauthor #5
Search for MicroRNAs Expressed by Intracellular Bacterial Pathogens in Infected Mammalian Cells
201467 citationsauthor #8
Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.
20138 citationsauthor #9
Self and Non-self Discrimination of Intracellular Membranes by the Innate Immune System
201345 citationsauthor #1
IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins
2013181 citationsauthor #9
Compensatory T Cell Responses in IRG-Deficient Mice Prevent Sustained Chlamydia trachomatis Infections
201155 citationsauthor #1
Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating Macroautophagy
201184 citationsauthor #9
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole
2010203 citationsauthor #6
Opinion Modeling Infectious Disease in Mice : Co-Adaptation and the Role of Host-Specific IFN c Responses
20092 citationsauthor #1
Balance of Irgm protein activities determines IFN‐γ‐induced host defense
200982 citationsauthor #6
Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.
200965 citationsauthor #2
Modeling Infectious Disease in Mice: Co-Adaptation and the Role of Host-Specific IFNγ Responses
200950 citationsauthor #1
Chlamydia muridarum Evades Growth Restriction by the IFN-γ-Inducible Host Resistance Factor Irgb101
2008134 citationsauthor #1
Resistance Factor Irgb10-Inducible Host g Restriction by the IFN-Evades Growth Chlamydia muridarum
20080 citationsauthor #6
Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways
2007149 citationsauthor #1
Genetic analysis of susceptibility to Chlamydia trachomatis in mouse
200654 citationsauthor #4
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice
2006114 citationsauthor #2
A Truncated Isoform of c-Mpl with an Essential C-terminal Peptide Targets the Full-length Receptor for Degradation*
200424 citationsauthor #1
Regulation of thrombopoietin receptor expression and function
20040 citationsauthor #1
Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders.
2003163 citationsauthor #4
Immunity to homologous rotavirus infection in adult mice
20004 citationsauthor #1
Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth
2000188 citationsauthor #1
Exploitation of macrophages as a replication niche by Legionella pneumophila: response.
20001 citationsauthor #2
Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth
1999268 citationsauthor #1
Antennnal olfactory and behavioral response of southern pine beetle,Dendroctonus frontalis, to analogs of its aggregation pheromone frontalin
198811 citationsauthor #6

TIMELINE

1988 11 citations

1999 268 citations

2000 193 citations

2003 163 citations

2004 24 citations

2006 168 citations

2007 149 citations

2008 134 citations

2009 199 citations

2010 203 citations

2011 139 citations

2013 234 citations

2014 482 citations

2015 418 citations

2016 1,957 citations

2017 658 citations

2018 103 citations

2019 122 citations

2020 283 citations

2021 67 citations

2022 281 citations

2023 139 citations

2024 19 citations

2025 5 citations

COAUTHOR MAP

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