B. Afzali

The CD4 T cell-intrinsic C3-like molecule CD109 prevents hyper-inflammatory T cell responses
20240 citationsauthor #9
Anakinra-associated renal amyloidosis.
20246 citationsauthor #5
Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark
202410 citationsauthor #27
Prostate epithelial cell intrinsic C3 represses MYC-driven tumorigenesis
20240 citationsauthor #14
The role of transcription factors in shaping regulatory T cell identity
202390 citationsauthor #3
Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
202338 citationsauthor #19
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection.
202375 citationsauthor #30
Successful Treatment of Paecilomyces variotii Pneumonia and Lupus Nephritis With Posaconazole-Cyclophosphamide Co-administration Without Drug Interaction-Induced Toxicity.
20232 citationsauthor #16
CD4 T cell intrinsic arginase 1 controls the kinetics of Th1 induction and contraction
20230 citationsauthor #15
Transcription factor EGR2 controls homing and pathogenicity of T_H17 cells in the central nervous system
202311 citationsauthor #19
PI3Kδ shapes Th2 lineage restriction through coordination of IL-2 signaling, Foxo1 inactivation and epigenetic remodeling
20230 citationsauthor #10
183 Exploring the role of C5aR2 in neutrophil-driven autoimmune diseases: An often overlooked player in the pathogenesis of epidermolysis bullosa acquisita
20230 citationsauthor #13
A comprehensive single cell data analysis of in lymphoblastoid cells reveals the role of Super-enhancers in maintaining EBV latency
20221 citationsauthor #17
EBV-associated diseases: Current therapeutics and emerging technologies
202271 citationsauthor #2
Complement activates an autocrine Vitamin D system that recruits a defined transcription factor network to shut down pro-inflammatory programs of Th1 cells
20220 citationsauthor #29
Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations.
202231 citationsauthor #5
Folic acid-mediated fibrosis is driven by C5a receptor 1-mediated activation of kidney myeloid cells.
202212 citationsauthor #10
A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super‐enhancers in maintaining EBV latency
20227 citationsauthor #18
Systematic Single Cell Pathway Analysis (SCPA) reveals novel pathways engaged during early T cell activation
20222 citationsauthor #10
A central role for STAT5 in the transcriptional programing of T helper cell metabolism
202240 citationsauthor #8
1,25-Dihydroxyvitamin D3 suppresses CD4+ T-cell effector functionality by inhibition of glycolysis
202212 citationsauthor #8
Systematic single-cell pathway analysis to characterize early T cell activation.
202272 citationsauthor #11
MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.
202148 citationsauthor #14
Response to Comments on “Aberrant type 1 immunity drives susceptibility to mucosal fungal infections”
20217 citationsauthor #39
BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8+ T cells
2021149 citationsauthor #16
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
20215 citationsauthor #5
Autocrine Vitamin D-signaling switches off pro-inflammatory programs of Th1 cells
2021154 citationsauthor #29
Fibroblast tissue priming-not so nice to C you!
202110 citationsauthor #1
A functional map of genomic HIF1α-DNA complexes in the eye lens revealed through multiomics analysis
20216 citationsauthor #5
Reply to Grigoriev et al., “Sequences of SARS-CoV-2 ‘Hybrids’ with the Human Genome: Signs of Non-coding RNA?”
20210 citationsauthor #11
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections
2021128 citationsauthor #39
Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells
20212 citationsauthor #16
Renal diseases and the role of complement: Linking complement to immune effector pathways and therapeutics.
202113 citationsauthor #2
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
2021116 citationsauthor #23
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells
202144 citationsauthor #29
Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual
202129 citationsauthor #11
Host-virus chimeric events in SARS-CoV2 infected cells are infrequent and artifactual
20218 citationsauthor #11
The state of complement in COVID-19
2021233 citationsauthor #1
BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells
20210 citationsauthor #16
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation
2021173 citationsauthor #29
Diapedesis and LFA-1 mediate tissue immune cell effector activity via intrinsic complement C3 licensing
20200 citationsauthor #12
SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyperactivation
202028 citationsauthor #13
Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
202091 citationsauthor #29
Diapedesis-induced integrin signalling via LFA-1 facilitates tissue immunity by inducing intrinsic complement C3 expression in immune cells
20201 citationsauthor #26
Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid Cells
202038 citationsauthor #10
Pericyte and Macrophage C5aR1 Mediate Renal Fibrosis
20200 citationsauthor #6
The role of Virostatic genes in modulating Immune Checkpoints in Epstein-Barr Virus associated Tumors
20200 citationsauthor #11
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19
202024 citationsauthor #25
RNF144A shapes the hierarchy of cytokine signaling to provide protective immunity against influenza
20193 citationsauthor #1
Integrated pan-cancer map of EBV-associated neoplasms reveals functional host-virus interactions.
201952 citationsauthor #14
A New crucial role for complement receptor CD46 in chromatin packaging and direct gene regulation
20190 citationsauthor #5
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells
2019112 citationsauthor #15
Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa
201889 citationsauthor #25
Complement receptor CD46 is a key co-stimulator for optimal human CD8+ T cell effector function
20180 citationsauthor #8
STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells
201832 citationsauthor #9
Intracellular C3a maintains normal cell homeostasis in prostate epithelial cells
20180 citationsauthor #10
Unexpected Roles for Intracellular Complement in the Regulation of Th1 Responses.
201823 citationsauthor #2
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism
201898 citationsauthor #19
Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development
201748 citationsauthor #9
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
2017126 citationsauthor #1
Intrinsic NLRP3 inflammasome activity is critical for normal adaptive immunity via regulation of IFN-γ in CD4+ T cells
20161 citationsauthor #18
Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells
201673 citationsauthor #11
Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells
20160 citationsauthor #13
Author response: Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions
20161 citationsauthor #6
Autocrine NLRP3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4+T cells
20161 citationsauthor #16
The C3-like molecule CD109 controls Th1 versus Th17 induction in CD4+ T cells
20162 citationsauthor #9
Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions
201680 citationsauthor #6
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
2016465 citationsauthor #18
Janus Kinases (JAKs)/STAT Pathway
20160 citationsauthor #1
SP399BENEFICIAL IMMUNOMODULATORY EFFECT OF CHOLECALCIFEROL REPLETION IN CKD PATIENTS : DOWN-REGULATION OF CELL SURFACE HLA-DR EXPRESSION MAY EXPLAIN REDUCTION IN INFLAMMATION
20150 citationsauthor #5
EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion
2015136 citationsauthor #5
Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses
2015238 citationsauthor #14
Regulatory T-cell therapy in the induction of transplant tolerance: the issue of subpopulations.
201474 citationsauthor #7
272 In Vitro Generated Regulatory T Cells From Crohn's Disease Patients’ Blood Home to Inflamed Human Small Bowel In Vivo
20130 citationsauthor #6
Thymic Versus Induced Regulatory T Cells – Who Regulates the Regulators?
201397 citationsauthor #6
Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations
2013142 citationsauthor #9
Assessment of regulatory T-cell function in forthcoming clinical trials of cell therapy
20133 citationsauthor #2
Evidence for intracellular complement activation vital to Th1 immunity
20131 citationsauthor #13
CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner
2013113 citationsauthor #1
Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.
201381 citationsauthor #1
Su1266 In Vitro Generated Regulatory T Cells From Blood Suppress Mucosal Effector T Cells in Crohn's Disease Patients
20130 citationsauthor #8
Regulatory T cells in renal cell carcinoma: additional fuel to the bonfire of debate
20130 citationsauthor #1
Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation
2013528 citationsauthor #19
Differential effects of rapamycin and retinoic acid on expansion , stability and suppressive qualities of human CD 4 + CD 25 + FOXP 3 + Treg subpopulations
201210 citationsauthor #9
Mineral and bone disease - CKD 1-5
20120 citationsauthor #35
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy.
201289 citationsauthor #2
Faculty Opinions recommendation of Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation.
20120 citationsauthor #2
Core Concepts in Renal Transplantation
20127 citationsauthor #1
Faculty Opinions recommendation of Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative.
20120 citationsauthor #2
(MDS) regulatory T cells in myelodysplastic syndrome + Foxp3 high CD25 + CD4
20120 citationsauthor #10
Faculty Opinions recommendation of Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases.
20110 citationsauthor #2
IL-2 Regulates Expression of C-MAF in Human CD4 T Cells
201132 citationsauthor #2
Relative Resistance of Human CD4+ Memory T Cells to Suppression by CD4+CD25+ Regulatory T Cells
201137 citationsauthor #1
Cell therapy to promote transplantation tolerance: a winning strategy?
201123 citationsauthor #7
Anti-TNFalpha therapy--killing two birds with one stone?
201013 citationsauthor #3
T-cell alloimmunity and chronic allograft dysfunction.
201063 citationsauthor #2
Optimisation of Treg cells functions by alteration of in vitro culture conditions
20100 citationsauthor #4
Graft Rejection: Immunological Suppression
20102 citationsauthor #1
Infections in hemodialysis
20091 citationsauthor #1
The T helper 17–regulatory T cell axis in transplant rejection and tolerance
200989 citationsauthor #2

PROFILE

PAPERS

TIMELINE

COAUTHOR MAP

CONCEPT FOOTPRINT