J. Niederkorn

Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors.
20247 citationsauthor #4
“Corneal Nerves, CD11c+ Dendritic Cells and Their Impact on Ocular Immune Privilege”
202114 citationsauthor #1
Corneal Nerve Ablation Abolishes Ocular Immune Privilege by Downregulating CD103 on T Regulatory Cells
202014 citationsauthor #2
The biology of Acanthamoeba keratitis.
202051 citationsauthor #1
The Eye Sees Eye to Eye With the Immune System: The 2019 Proctor Lecture
201925 citationsauthor #1
Defective FasL expression is associated with increased resistance to melanoma liver metastases and enhanced natural killer cell activity.
20191 citationsauthor #4
Deregulation of Acanthamoeba castellanii steroidogenesis is amoebicidal and protects cultured corneal cells from Ac attack
20191 citationsauthor #8
Severing corneal nerves induces the release of substance P which converts ocular surface CD11c+ cells to contrasuppressor cells that abolish ocular immune privilege.
20180 citationsauthor #4
Role of Antigen-presenting Cells within Conjunctiva-associated Lymphoid Tissue in the Induction of Ocular Allergy
20180 citationsauthor #4
Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation
20189 citationsauthor #4
Corneal nerve ablation in one eye induces Langerhans cell infiltration into both eyes and abolishes immune privilege in both eyes
20170 citationsauthor #1
Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens
201714 citationsauthor #5
Pathobiology and Immunobiology of Acanthamoeba Keratitis: Insights from Animal Models 
201746 citationsauthor #2
Natural Killer T Cells Contribute to Neutrophil Recruitment and Ocular Tissue Damage in a Model of Intraocular Tumor Rejection
20164 citationsauthor #2
Immunology of the Eye
20160 citationsauthor #1
Mechanisms of immune deviation
20160 citationsauthor #1
Growth and Metastasis of Intraocular Tumors in Aged Mice
201613 citationsauthor #3
Immunology of Uveitis
20162 citationsauthor #5
Effect of severing corneal nerves on the induction of immune tolerance during corneal transplantation
20160 citationsauthor #3
Role of interferon‐γ and cytotoxic T lymphocytes in intraocular tumor rejection
201616 citationsauthor #3
NKT cells act through third party bone marrow‐derived cells to suppress NK cell activity in the liver and exacerbate hepatic melanoma metastases
201527 citationsauthor #5
Second corneal allografts ablate T regulatory cells that are induced by first corneal allografts and produce a permanent loss of immune privilege in both eyes
20150 citationsauthor #1
Immunology of Corneal Allografts: Insights from Animal Models.
201512 citationsauthor #1
Parasite Eccentricities
20150 citationsauthor #1
Advances on Non-CD4 + Foxp3+ T Regulatory Cells: CD8+, Type 1, and Double Negative T Regulatory Cells in Organ Transplantation
201564 citationsauthor #2
Baseline Delayed-Type Hypersensitivity and Desiccating Stress- Induced Dry Eye are Significantly Influenced by Thermoneutral Housing Temperature
20150 citationsauthor #5
Severing Corneal Nerves in One Eye Induces Sympathetic Loss of Immune Privilege and Promotes Rejection of Future Corneal Allografts Placed in Either Eye
201571 citationsauthor #6
Interferon-gamma is required for protecting against intraocular tumor growth after peripheral immunization but not for the generation of tumor-specific cytotoxic T-lymphocytes.
20150 citationsauthor #2
Liver NKT cells enhance, rather than inhibit, liver metastases arising from intraocular melanomas in mice
20140 citationsauthor #1
Impact of the Host Microbiota on the Development of Murine Desiccating Stress-Induced Dry Eye Disease
20141 citationsauthor #7
Role of CD147 in Experimental Autoimmune Anterior Uveitis (EAAU)
20140 citationsauthor #7
Stress-Induced Damage to the Ocular Surface Resembling Dry Eye can Occur Independently of Chronic T cell-mediated Disease
20140 citationsauthor #8
Regulatory T cell mediated suppression of dendritic cells in a mouse model of dry eye
20140 citationsauthor #8
Chapter-12 Innate Immune System and its Impact on Immune Privilege in the Eye
20130 citationsauthor #1
CD8+ Cells Regulate the T helper-17 Response in an Experimental Murine Model of Sjögren Syndrome
201345 citationsauthor #8
Corneal Transplantation and Immune Privilege
2013110 citationsauthor #1
IFN‐γ Blocks CD4+CD25+ Tregs and Abolishes Immune Privilege of Minor Histocompatibility Mismatched Corneal Allografts
201318 citationsauthor #2
Penetrating keratoplasty to one eye abolishes immune privilege and promotes corneal allograft rejection in the opposite eye, even to grafts from unrelated donors
20131 citationsauthor #1
Epigenetic regulation of CXCR4 expression by the ocular microenvironment.
201311 citationsauthor #2
Liver natural killer T cells enhance, rather than inhibit, liver metastases arising from intraocular melanomas in mice. (P2087)
20130 citationsauthor #3
Plasmacytoid Dendritic Cells are the Primary Source of IFN-α During the Immunopathogenesis of Desiccating Stress-Induced Dry Eye Disease
20134 citationsauthor #7
Development, Alteration and Real Time Dynamics of Conjunctiva-Associated Lymphoid Tissue
201338 citationsauthor #8
Mice with Desiccating Stress-Induced Dry Eye Develop Trigeminal Neuralgia, Despite Decreased Corneal Sensitivity and Nerve Fiber Degeneration
20130 citationsauthor #7
Penetrating keratoplasty to one eye abolishes immune privilege for corneal allograft placed into the other eye. (P2164)
20130 citationsauthor #2
Allergic Conjunctivitis Renders CD4+ T Cells Resistant to T Regulatory Cells and Exacerbates Corneal Allograft Rejection
201322 citationsauthor #3
Potential Regulatory T Cell Mechanisms Of Immune Suppression In A Mouse Model Of Dry Eye
20130 citationsauthor #6
New Twists to an Old Story: Novel Concepts in the Pathogenesis of Allergic Eye Disease
201346 citationsauthor #7
Anatomy and Pathology Epigenetic Regulation of CXCR 4 Expression by the Ocular Microenvironment
20130 citationsauthor #2
Chapter-16 Role of the Innate Immune System in Corneal Transplantation
20130 citationsauthor #1
Autoantibodies contribute to the immunopathogenesis of experimental dry eye disease.
201271 citationsauthor #10
IFN‐γ‐independent intraocular tumor rejection is mediated by a macrophage‐dependent process that leaves the eye intact
20125 citationsauthor #3
Allergic Conjunctivitis Exacerbates Corneal Allograft Rejection by Rendering Effector Cells Resistant to T Regulatory Cell-mediated Suppression
20120 citationsauthor #3
Ocular Immune Privilege and Ocular Melanoma: Parallel Universes or Immunological Plagiarism?
201274 citationsauthor #1
Cornea Autoantibodies Contribute to the Immunopathogenesis of Experimental Dry Eye Disease
20120 citationsauthor #10
Alterations in Corneal Nerve Fiber Density and Pain Markers during the Progression of Desiccating Stress-Induced Dry Eye Disease
20120 citationsauthor #7
Expression Of Adhesion Molecules During Development Of Conjunctiva-Associated Lymphoid Tissue
20120 citationsauthor #4
Penetrating Keratoplasty To One Eye Abolishes Immune Privilege For Corneal Allografts Placed Into The Other Eye
20120 citationsauthor #3
Role of IFN‐γ in the establishment of anterior chamber‐associated immune deviation (ACAID)‐induced CD8+ T regulatory cells
201217 citationsauthor #3
NK Cells Promote Th-17 Mediated Corneal Barrier Disruption in Dry Eye
2012109 citationsauthor #11
Inhibition Of Interferon- Promotes Survival Of MHC-mismatched Corneal Allografts But Exacerbates Rejection Of MHC Plus Minor Histocompatibility Antigen-mismatched Corneal Allografts
20120 citationsauthor #1
The role of NKT cells in immune evasion of liver metastases arising from intraocular tumors (74.12)
20120 citationsauthor #2
Plasmacytoid Dendritic Cells are Modulated During the Immunopathogenesis of Desiccating Stress-Induced Experimental Dry Eye
20122 citationsauthor #8
Role Of Interferon- And IL-17 In The Immune Rejection Of Intraocular Tumors
20110 citationsauthor #1
Spontaneous Autoimmune Inflammation of the Ocular Surface Mucosa in Aged CD4-DNTGFβRII Mice
20117 citationsauthor #3
IL-17A–Dependent CD4+CD25+ Regulatory T Cells Promote Immune Privilege of Corneal Allografts
201153 citationsauthor #3
Ocular Surface Antigen Presenting Cells are Necessary for the Generation of Autoreactive T cells during Experimental Dry Eye
20110 citationsauthor #6
This information is current as Autoimmune Lacrimal Keratoconjunctivitis Autoreactive T Cell-Mediated Experimental Ocular Surface APCs Are Necessary for Pflugfelder and
20110 citationsauthor #4
IL-17–Dependent, IFN-γ–Independent Tumor Rejection Is Mediated by Cytotoxic T Lymphocytes and Occurs at Extraocular Sites, but Is Excluded from the Eye
20113 citationsauthor #3
γδ T cells are required for maximal expression of allergic conjunctivitis.
201121 citationsauthor #4
The Role of Allergic Conjunctivitis in the Exacerbation of Corneal Allograft Rejection
20110 citationsauthor #3
Cytokine Requirement, Molecular Mechanisms, and Kinetics of CD4+CD25+ T Regulatory Cells in the Establishment of Corneal Immune Privilege
20110 citationsauthor #3
Abrogating TNF-α expression prevents bystander destruction of normal tissues during iNOS-mediated elimination of intraocular tumors.
201111 citationsauthor #3
Autoantibodies Contribute to the Immunopathogenesis of Dry Eye in a Mouse Model of Autoimmune Lacrimal Keratoconjunctivitis
20110 citationsauthor #8
Cornea: Window to Ocular Immunology.
201150 citationsauthor #1
Integrated Systems and Technologies Integration of Genotypic and Phenotypic Screening Reveals Molecular Mediators of Melanoma – Stromal Interaction
201130 citationsauthor #36
NKT cell exacerbation of liver metastases arising from melanomas transplanted into either the eyes or spleens of mice.
201136 citationsauthor #6
Disruption of TGF-β Signaling Improves Ocular Surface Epithelial Disease in Experimental Autoimmune Keratoconjunctivitis Sicca
201163 citationsauthor #9
Desiccating stress induces CD4+ T-cell-mediated Sjögren's syndrome-like corneal epithelial apoptosis via activation of the extrinsic apoptotic pathway by interferon-γ.
201178 citationsauthor #8
Apoptosis and homeostasis in the eye
20112 citationsauthor #1
Comprar Immunology, inflammation and diseases of the eye | Darlene A. Dartt | 9780123819741 | Academic Press
20112 citationsauthor #4
CD8+ T Regulatory Cells Require IFN- to Mediate Anterior Chamber-Associated Immune Deviation (ACAID) Suppression
20110 citationsauthor #2
Conjunctival antigen presenting cells: Sentinels for ocular surface inflammation
20110 citationsauthor #1
Ocular Surface APCs Are Necessary for Autoreactive T Cell-Mediated Experimental Autoimmune Lacrimal Keratoconjunctivitis
2011147 citationsauthor #5
Disruption of TGF-β Signaling Improves Dry Eye Disease
20110 citationsauthor #8
Comprar Ocular periphery and disorders | Darlene A. Dartt | 9780123820426 | Academic Press
20110 citationsauthor #6
Characterization of Intraepithelial Lymphocyte Populations and Their Changes in Response to Experimental Desiccating Stress
20110 citationsauthor #8
The Functional Role of B Cells in a Mouse Model of Autoimmune Lacrimal Keratoconjunctivitis: Adoptive Transfer of Serum, but Not B Cells Alone, Mediates Ocular Surface Inflammation
20100 citationsauthor #7
Role of TNF- and iNOS in CD4+ T Cell-Mediated Immune Responses That Reject Intraocular Tumors but Destroy the Eye
20100 citationsauthor #3
Immunobiology of Uveal Melanoma
20100 citationsauthor #3
Paradigm shifts in the role of CD4+ T cells in keratoplasty.
201017 citationsauthor #3
Innate T Cells Are Necessary for Maximal Expression of Allergic Conjunctivitis
20100 citationsauthor #4
Dynamic Immunoregulatory Processes that Sustain Immune Privilege in the Eye
20107 citationsauthor #1
Allergic Conjunctivitis Exacerbates Corneal Allograft Rejection by Activating Th1 and Th2 Alloimmune Responses
201023 citationsauthor #1
Immune Privilege of Corneal Allografts
201060 citationsauthor #1
Immunopathology and Infectious Diseases Spontaneous Autoimmune Dacryoadenitis in Aged CD 25 KO Mice
20100 citationsauthor #6
Immunopathogenesis in a Mouse Model of Lacrimal Keratoconjunctivitis is Antigen Specific
20100 citationsauthor #5
Polarized Th1 and Th17 Cells Derived From a Mouse Model of Dry Eye Induce Ocular Surface Disease
20100 citationsauthor #7
NK cells in the eye
20107 citationsauthor #1
Autoimmunity at the ocular surface: pathogenesis and regulation
2010146 citationsauthor #5
Th2 Alloimmune Responses Allograft Rejection by Activating Th1 and Allergic Conjunctivitis Exacerbates Corneal
20100 citationsauthor #3

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