G. Guarguaglini

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Aliases
G Guarguaglini, G. Guarguaglini, Giulia Guarguaglini
Publication record
56 papers · 3,287 citations · H-index 25

PAPERS

AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation
202314 citationsauthor #11
When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases
20238 citationsauthor #4
AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation
20237 citationsauthor #20
Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1
20225 citationsauthor #12
PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc
202112 citationsauthor #18
Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer
202145 citationsauthor #7
A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc
20210 citationsauthor #17
M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines
20217 citationsauthor #9
Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A
20216 citationsauthor #3
Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit
202025 citationsauthor #10
AURKA destruction is decoupled from its activity at mitotic exit but is essential to suppress interphase activity
202012 citationsauthor #6
The Aurora-A/TPX2 Axis Directs Spindle Orientation by Regulating NuMa and Microtubule Dynamics
20201 citationsauthor #8
AURKA destruction is decoupled from its activity at mitotic exit but essential to suppress interphase activity.
20207 citationsauthor #6
X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics
20208 citationsauthor #8
X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics
20201 citationsauthor #8
The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability.
202039 citationsauthor #10
Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling
201913 citationsauthor #5
AURKA destruction is decoupled from its activity at mitotic exit but suppresses interphase activity
20190 citationsauthor #6
Actin-dependent regulation of cilia length by the inverted formin FHDC1
201838 citationsauthor #3
Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays
201816 citationsauthor #6
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex
201721 citationsauthor #6
Use of Ferritin-Based Metal-Encapsulated Nanocarriers as Anticancer Agents
201716 citationsauthor #6
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma
201783 citationsauthor #3
NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation.
201690 citationsauthor #8
TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure
201618 citationsauthor #6
Amorphous silica nanoparticles alter microtubule dynamics and cell migration
201525 citationsauthor #5
The centrosome: a multifaceted cellular weapon against chromosome instability
20151 citationsauthor #1
Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly
201592 citationsauthor #3
Immunofluorescence methods in studies of the GTPase RAN and its effectors in interphase and in mitotic cells.
20141 citationsauthor #1
The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy
201445 citationsauthor #8
TPX2 (TPX2, microtubule-associated, homolog (Xenopus laevis))
20131 citationsauthor #2
Self-assembling peptide hydrogels promote microglial cells proliferation and NGF production
201233 citationsauthor #3
Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high‐risk neuroblastoma
201217 citationsauthor #7
HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.
201258 citationsauthor #11
Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces
201159 citationsauthor #4
Control of Aurora-A stability through interaction with TPX2
201186 citationsauthor #7
Result of the chromosomal anomaly
20100 citationsauthor #9
Ran control of mitosis in human cells: gradients and local signals.
201011 citationsauthor #3
The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?
201084 citationsauthor #5
Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells.
200890 citationsauthor #3
Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity
200862 citationsauthor #6
A Functional Interplay Between Aurora-A, Plk1 and TPX2 at Spindle Poles: Plk1 Controls Centrosomal Localization of Aurora-A and TPX2 Spindle Association
2006142 citationsauthor #3
Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects
200585 citationsauthor #3
The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles.
2005255 citationsauthor #1
Importin β is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells
200489 citationsauthor #4
Regulation of the centrosome cycle by protein phosphorylation
20030 citationsauthor #4
Identification of a new centrosomal protein interacting with the Polo-like kinase
20030 citationsauthor #1
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.
2001299 citationsauthor #4
Ran Induces Spindle Assembly by Reversing the Inhibitory Effect of Importin α on TPX2 Activity
2001562 citationsauthor #4
Mitotic Control by Ran and RanBP1 in Mammalian Cells
20010 citationsauthor #2
Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo.
200081 citationsauthor #1
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
1999524 citationsauthor #2
Two E2F Sites Control Growth-regulated and Cell Cycle-regulated Transcription of the Htf9-a/RanBP1 Gene through Functionally Distinct Mechanisms*
199928 citationsauthor #2
Interactions with Single-stranded and Double-stranded DNA-binding Factors and Alternative Promoter Conformation upon Transcriptional Activation of the Htf9-a/RanBP1 andHtf9-c Genes*
199817 citationsauthor #3
Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.
199743 citationsauthor #2
Atlas of Genetics and Cytogenetics in Oncology and Haematology TPX 2 ( TPX 2 , microtubule-associated , homolog ( Xenopus laevis ) )
year unknown0 citationsauthor #2

TIMELINE

1997 43 citations

1998 17 citations

1999 552 citations

2000 81 citations

2001 861 citations

2003 0 citations

2004 89 citations

2005 340 citations

2006 142 citations

2008 152 citations

2010 95 citations

2011 145 citations

2012 108 citations

2013 1 citations

2014 46 citations

2015 118 citations

2016 108 citations

2017 120 citations

2018 54 citations

2019 13 citations

2020 93 citations

2021 70 citations

2022 5 citations

2023 29 citations

Unknown 0 citations

G. Guarguaglini

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