Atlas of Genetics and Cytogenetics in Oncology and Haematology TPX 2 ( TPX 2 , microtubule-associated , homolog ( Xenopus laevis ) )

No abstract is available for this paper.

• Publication year

  year unknown

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Cancer Therapy : Preclinical The Investigational Aurora Kinase A Inhibitor MLN 8237 Induces Defects in Cell Viability and Cell-Cycle Progression in Malignant Bladder Cancer Cells In Vitro and In Vivo

  2013cited by this paper
• Network-based approach identified cell cycle genes as predictor of overall survival in lung adenocarcinoma patients.

  2013cited by this paper
• Functional Genetic Screens Identify Genes Essential for Tumor Cell Survival in Head and Neck and Lung Cancer

  2013cited by this paper
• Integrated cross-species transcriptional network analysis of metastatic susceptibility

  2012cited by this paper
• Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high‐risk neuroblastoma

  2012cited by this paper
• DPEP1 Inhibits Tumor Cell Invasiveness, Enhances Chemosensitivity and Predicts Clinical Outcome in Pancreatic Ductal Adenocarcinoma

  2012cited by this paper
• High-Throughput Transcriptomic and RNAi Analysis Identifies AIM1, ERGIC1, TMED3 and TPX2 as Potential Drug Targets in Prostate Cancer

  2012cited by this paper
• The TPX2 gene is a promising diagnostic and therapeutic target for cervical cancer.

  2012cited by this paper
• Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation*

  2012cited by this paper
• TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression

  2011cited by this paper
• The nuclear scaffold protein SAF-A is required for kinetochore–microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles

  2011cited by this paper
• Control of Aurora-A stability through interaction with TPX2

  2011cited by this paper
• Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain

  2011cited by this paper
• Identification of a TPX2-Like Microtubule-Associated Protein in Drosophila

  2011cited by this paper
• TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle

  2011cited by this paper
• Identification of Gene Markers Associated With Aggressive Meningioma by Filtering Across Multiple Sets of Gene Expression Arrays

  2011cited by this paper
• Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma.

  2010cited by this paper
• Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux

  2010cited by this paper
• Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma

  2010cited by this paper
• Novel Binding of the Mitotic Regulator TPX2 (Target Protein for Xenopus Kinesin-like Protein 2) to Importin-α*

  2010cited by this paper
• Identification of Candidate Growth Promoting Genes in Ovarian Cancer through Integrated Copy Number and Expression Analysis

  2010cited by this paper
• The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?

  2010cited by this paper
• The diagnostic value of Ki-67 and repp86 in distinguishing between benign and malignant mesothelial proliferations.

  2009cited by this paper
• Validation of TPX2 as a Potential Therapeutic Target in Pancreatic Cancer Cells

  2009cited by this paper
• Plant TPX2 and related proteins

  2009cited by this paper
• Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas.

  2009cited by this paper
• The role of Hklp2 in the stabilization and maintenance of spindle bipolarity.

  2009cited by this paper
• Expression of TPX2 in salivary gland carcinomas.

  2009cited by this paper
• Kif15 cooperates with eg5 to promote bipolar spindle assembly.

  2009cited by this paper
• Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System

  2009cited by this paper
• TPX2 in malignantly transformed human bronchial epithelial cells by anti-benzo[a]pyrene-7,8-diol-9,10-epoxide.

  2008cited by this paper
• The Plant TPX2 Protein Regulates Prospindle Assembly before Nuclear Envelope Breakdown[W]

  2008cited by this paper
• Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

  2008cited by this paper
• Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: Potential role in progression

  2008cited by this paper
• Spindle pole regulation by a discrete Eg5-interacting domain in TPX2.

  2008cited by this paper
• Journal of Translational Medicine BioMed Central

  2007cited by this paper
• Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

  2007cited by this paper
• ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

  2007cited by this paper
• Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer.

  2006cited by this paper
• A Functional Interplay Between Aurora-A, Plk1 and TPX2 at Spindle Poles: Plk1 Controls Centrosomal Localization of Aurora-A and TPX2 Spindle Association

  2006cited by this paper
• A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

  2006cited by this paper
• Anaphase-Promoting Complex/Cyclosome Controls the Stability of TPX2 during Mitotic Exit

  2005cited by this paper
• Restricted-Expressed Proliferation–Associated Protein (Repp86) Expression in Squamous Cell Carcinoma of the Oral Cavity

  2005cited by this paper
• High-resolution genomic profiles of human lung cancer.

  2005cited by this paper
• An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles.

  2005cited by this paper
• Importin β is transported to spindle poles during mitosis and regulates Ran-dependent spindle assembly factors in mammalian cells

  2004cited by this paper
• Characterization of the TPX 2 Domains Involved in Microtubule Nucleation and Spindle Assembly in Xenopus Egg Extracts

  2004cited by this paper
• Importin α‐regulated nucleation of microtubules by TPX2

  2003cited by this paper
• Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.

  2003cited by this paper
• Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

  2003cited by this paper
• hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division.

  2002cited by this paper
• Human TPX2 is required for targeting Aurora-A kinase to the spindle

  2002cited by this paper
• Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

  2002cited by this paper
• Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.

  2001cited by this paper
• Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.

  1999cited by this paper
• A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

  1999cited by this paper
• p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M.

  1997cited by this paper

• No citing papers are available for this paper.