T. Perls

PROFILE

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Aliases
T Perls, T T Perls, T. T. Perls, Thomas Perls, Tom Perls, Thomas T. Perls, Thomas T Perls
Publication record
280 papers · 12,755 citations · H-index 60

PAPERS

Causal mediation analysis of the neuroprotection of APOE2 through lipid pathways
20250 citationsauthor #5
Pathway analysis of cognitive resilience factors and cognitive function in the Long Life Family Study (LLFS).
20250 citationsauthor #3
Whole blood transcriptional signatures of age and survival identified in Long Life Family and Integrative Longevity Omics Studies
20250 citationsauthor #19
Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity
20250 citationsauthor #7
SNP rs6543176 is associated with extreme human longevity but increased risk for cancer
20251 citationsauthor #13
The role of lipids in the effect of APOE2 on cognitive function: a causal mediation analysis
20250 citationsauthor #5
IPSC-based modeling of resiliency in centenarians reveals longevity-specific signatures
20250 citationsauthor #14
Robust Serum Proteomic Signatures of APOE2
20251 citationsauthor #21
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E
20250 citationsauthor #21
Additional Cover
20250 citationsauthor #15
A longevity‐specific bank of induced pluripotent stem cells from centenarians and their offspring
20244 citationsauthor #15
Cross-platform proteomics signatures of extreme old age
20241 citationsauthor #6
Estimating treatment effects from observational data under truncation by death using survival-incorporated quantiles
20240 citationsauthor #3
Metabolite signatures of chronological age, aging, survival, and longevity
202422 citationsauthor #31
The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank
20242 citationsauthor #11
Adherence to the Alternative Health Eating Index and Planetary Health Diet Index in the New England Centenarian Study
20240 citationsauthor #6
A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring
20240 citationsauthor #14
Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease
202411 citationsauthor #5
Cross-platform proteomics signatures of extreme old age
20244 citationsauthor #6
Mosaic chromosomal alterations and human longevity.
20235 citationsauthor #11
DETECTING COGNITIVE IMPAIRMENT FROM DIGITAL VOICE RECORDINGS OF A REPETITION TASK
20230 citationsauthor #4
Examination of Genetic Risk Factors for Alzheimer’s Disease in a Cohort of Familial Longevity: the Long Life Family Study
20230 citationsauthor #9
DISTANCE-BASED ANALYSIS OF LONGEVITY-RELATED METABOLOMIC PROFILES
20230 citationsauthor #6
Signatures of Neuropsychological Test Results in the Long Life Family Study: A Cluster Analysis
20235 citationsauthor #6
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
20232 citationsauthor #114
SERUM METABOLOMICS SIGNATURES OF EXTREME OLD AGE AND LONGEVITY
20230 citationsauthor #6
METABOLOMIC SIGNATURES OF AGE, EXTREME OLD AGE, AND LONGEVITY IN LONG LIFE FAMILY STUDY PARTICIPANTS
20230 citationsauthor #4
TRANSCRIPTOMIC SIGNATURES FOR AGING AND EXTREME OLD AGE IDENTIFIED IN THE LONG LIFE FAMILY STUDY
20230 citationsauthor #6
SuperAger Initiative: unlocking the genetic potential of exceptional longevity
20230 citationsauthor #6
Successful aging and its subtypes in centenarians: The Chinese experience
20233 citationsauthor #1
MOSAIC CHROMOSOMAL ALTERATIONS AND LONGEVITY
20220 citationsauthor #4
Digitally generated Trail Making Test data: Analysis using hidden Markov modeling
202217 citationsauthor #5
MEGA-ANALYSIS OF A CONSORTIUM OF FOUR CENTENARIAN STUDIES IDENTIFIES NOVEL EXTREME LONGEVITY VARIANTS
20220 citationsauthor #7
ARE RECENTLY INCARCERATED OLDER ADULTS MORE LIKELY TO DEVELOP DEMENTIA THAN THE NEVER INCARCERATED?
20221 citationsauthor #4
Evaluation of GENESIS, SAIGE, REGENIE and fastGWA-GLMM for genome-wide association studies of binary traits in correlated data
202211 citationsauthor #9
A metabolomic signature of the APOE2 allele
202214 citationsauthor #30
GENOME-WIDE ASSOCIATION STUDY OF EXTREME LONGEVITY USING WHOLE-GENOME SEQUENCING DATA
20220 citationsauthor #7
A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants
202212 citationsauthor #21
Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity
202261 citationsauthor #7
Association between late maternal age and age-related endophenotypes in the Long Life Family Study
20226 citationsauthor #3
Rare Genetic Variants Correlate with Better Processing Speed
20224 citationsauthor #13
Lexical markers from paragraph recall predict cognitive status
20221 citationsauthor #4
Slower Decline in Processing Speed Is Associated with Familial Longevity
20218 citationsauthor #6
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes
20215 citationsauthor #59
NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes
202146 citationsauthor #4
Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans
202178 citationsauthor #14
Correction to: Effect of longevity genetic variants on the molecular aging rate
20210 citationsauthor #11
APOE E2/E2 Is Associated with Slower Rate of Cognitive Decline with Age
202118 citationsauthor #6
Discovering Modality of Cognitive Function Using Clustering Analysis
20211 citationsauthor #2
Genetic Variants Correlate With Better Processing Speed
20210 citationsauthor #6
Effect of longevity genetic variants on the molecular aging rate
202121 citationsauthor #11
Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring
202112 citationsauthor #12
Association of fatigue, inflammation, and physical activity on gait speed: the Long Life Family Study
202128 citationsauthor #7
Digital Technology Differentiates Graphomotor and Information Processing Speed Patterns of Behavior
202111 citationsauthor #8
Cognitive Trajectories and Resilience in Centenarians-Findings From the 100-Plus Study.
20216 citationsauthor #1
Hematopoietic mosaic chromosomal alterations in the New England Centenarian Study.
20211 citationsauthor #4
Bayesian Variable Selection Utilizing Posterior Probability Credible Intervals
20211 citationsauthor #3
Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments
20216 citationsauthor #9
Longevity Studies in the New Normal: The Move to Virtual Assessment
20210 citationsauthor #8
The Long Life Family Study: Sequencing Exceptional Pedigrees for Rare Protective Variants
20200 citationsauthor #6
Early Differences in Cognition Associated With Familial Longevity and ApoE Genotype Using Digital Technology
20200 citationsauthor #6
COVID‐19 Deaths in Long‐Term Care Facilities: A Critical Piece of the Pandemic Puzzle
202071 citationsauthor #3
Complementary and Integrated Studies of Longevity and Healthy Aging
20200 citationsauthor #2
Pathway Analysis of Leisure Activity and Cognitive Function in the Long Life Family Study
20200 citationsauthor #5
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
202019 citationsauthor #129
Patterns of multi-domain cognitive aging in participants of the Long Life Family Study
202026 citationsauthor #9
Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.
202012 citationsauthor #6
Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study
20208 citationsauthor #6
Studying the Interplay Between Apolipoprotein E and Education on Cognitive Decline in Centenarians Using Bayesian Beta Regression
202011 citationsauthor #3
A comparison of genetic imputation methods using Long Life Family Study genotypes and sequence data with the 1000 Genome reference panel
20200 citationsauthor #15
Cancer Diagnosis, Polygenic Risk, and Longevity-Associated Variants.
20200 citationsauthor #8
Effect of Longevity Genetic Variants on the Molecular Aging Rate
20200 citationsauthor #8
Long Life Family Study Shows Reduced Coronary Artery Disease Despite High Polygenic Hazard Scores
20200 citationsauthor #5
A SERUM PROTEIN SIGNATURE OF APOE GENOTYPES IN CENTENARIANS
20190 citationsauthor #8
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.
2019106 citationsauthor #107
Genetic Markers of Extreme Human Longevity
20190 citationsauthor #4
CANCER: ARE OFFSPRING OF LONG-LIVED SIBLINGS BOTH ROBUST AND RESILIENT?
20190 citationsauthor #4
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
201940 citationsauthor #234
Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
20190 citationsauthor #11
LONG-LIVED INDIVIDUALS PRESENTING WITH LARGE BREAST AND COLON TUMORS HAVE A LOWER RISK OF CONCURRENT METASTASIS
20190 citationsauthor #8
Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism
201914 citationsauthor #12
PopCluster: an algorithm to identify genetic variants with ethnicity-dependent effects
20197 citationsauthor #9
A meta-analysis of genome-wide association studies identifies multiple longevity genes
2019299 citationsauthor #59
Healthy Longevity: An Introduction to the Special Issue.
20194 citationsauthor #1
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
2019333 citationsauthor #146
ADJUDICATION PILOT STUDY OF CAUSE OF DEATH IN THE LONG LIFE FAMILY STUDY
20190 citationsauthor #4
REDUCED COGNITIVE DECLINE WITH THE APOE ε2/ε2 GENOTYPE IN THE LONG LIFE FAMILY STUDY AND NEW ENGLAND CENTENARIAN STUDY
20190 citationsauthor #6
A catalog of genetic loci associated with kidney function from analyses of a million individuals
2019709 citationsauthor #207
A serum protein signature of APOE genotypes in centenarians
201931 citationsauthor #11
Age-related changes in lenses of healthy centenarian humans and old wild-type mice
20190 citationsauthor #6
Genetic associations with age of menopause in familial longevity.
201918 citationsauthor #6
CLONAL HEMATOPOIESIS IN A CENTENARIAN COHORT
20190 citationsauthor #3
THE LONGEVITY CONSORTIUM: MULTI-OMICS INTEGRATIVE APPROACH TO DISCOVERING HEALTHY AGING AND LONGEVITY DETERMINANTS
20191 citationsauthor #1
LONGITUDINAL CHANGES IN PULMONARY FUNCTION ELUCIDATE GENES ASSOCIATED WITH AGE-RELATED PULMONARY DECLINE IN LLFS
20180 citationsauthor #5
A novel healthy blood pressure phenotype in the Long Life Family Study
20187 citationsauthor #8
INTEGRATIVE ANALYSIS OF LONGITUDINAL CHANGES OF NEUROPSYCHOLOGICAL TESTS IN LONG LIFE FAMILY STUDY PARTICIPANTS
20180 citationsauthor #8
PROTEIN SIGNATURES OF EXTREME OLD AGE AND LONGEVITY
20180 citationsauthor #7
CAPTURING CHANGES OVER TIME IN LONGER LIVES IN THE LONG LIFE FAMILY STUDY
20180 citationsauthor #1
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
2018759 citationsauthor #159
Genetics of Circulating HbA1c Long-Term Change over Time in Nondiabetic Subjects—The Long Life Family Study
20180 citationsauthor #10

TIMELINE

1993 102 citations

1994 259 citations

1995 5 citations

1996 381 citations

1997 289 citations

1998 258 citations

1999 357 citations

2000 120 citations

2001 433 citations

2002 1,178 citations

2003 995 citations

2004 554 citations

2005 159 citations

2006 130 citations

2007 88 citations

2008 588 citations

2009 390 citations

2010 286 citations

2011 257 citations

2012 640 citations

2013 286 citations

2014 229 citations

2015 574 citations

2016 557 citations

2017 485 citations

2018 1,037 citations

2019 1,562 citations

2020 147 citations

2021 242 citations

2022 127 citations

2023 15 citations

2024 44 citations

2025 2 citations

Unknown 0 citations

T. Perls

PROFILE

PAPERS

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