L. Nadler

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Aliases
L M Nadler, Lee M. Nadler, Lee m. Nadler, Lee Nadler, L Nadler, Lee M Nadler, L. M. Nadler, Leem. Nadler, Lee Marshall Nadler
Publication record
335 papers · 25,100 citations · H-index 75

PAPERS

Infusion of Alloanergized Donor Lymphocytes after CD34-selected Haploidentical Myeloablative Hematopoietic Stem Cell Transplantation
20189 citationsauthor #13
Alloanergization of Human T Cells Results in Expansion of Alloantigen‐Specific CD8+CD28− Suppressor Cells
201425 citationsauthor #6
containing the bcl-2 rearrangement at evaluation and after treatment chain reaction amplifiable breakpoint of bcl-2 have residual cells All advanced stage non-Hodgkin's lymphomas with a polymerase
20130 citationsauthor #1
by Dexamethasone Muc-1 Core Protein Is Expressed on Multiple Myeloma Cells and Is Induced
20130 citationsauthor #3
after ex vivo costimulatory blockade: results of 2 phase 1 studies Outcome of alloanergized haploidentical bone marrow transplantation
20130 citationsauthor #5
cells and preferential enrichment for antigen specificity Engagement of CD83 ligand induces prolonged expansion of CD8+ T
20131 citationsauthor #2
antileukemic immune responses lymphoblastic leukemia and acute myeloid leukemia cells to induce colony-stimulating factor in human acute - granulocyte-macrophage Lentiviral vectors for efficient delivery of CD80 and
20130 citationsauthor #2
T-cell chemotaxis: potential as cellular adjuvants CD40-activated B-cells express full 'lymph node homing triad' and induce
20130 citationsauthor #7
in First Complete Remission CD6-Depleted Allogeneic Bone Marrow Transplantation for Acute Leukemia
20130 citationsauthor #4
inducible gene expression, without significant toxicity - β / α interferon- rituximab in patients with non-Hodgkin lymphoma: increased Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and
20130 citationsauthor #1
antigen-presenting cells: potential for clinical application efficiently induced by means of CD40-activated B cells as Human primary and memory cytotoxic T lymphocyte responses are
20130 citationsauthor #6
discovery in T-ALL An IL-7-dependent human leukemia T-cell line as a valuable tool for drug
20130 citationsauthor #2
lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase Interleukin-7 promotes survival and cell cycle progression of T-cell acute
20130 citationsauthor #3
Ex Vivo Alloanergization with Belatacept: A Strategy to Selectively Modulate Alloresponses after Transplantation
201222 citationsauthor #4
IL-21 Can Supplement Suboptimal Lck-Independent MAPK Activation in a STAT-3–Dependent Manner in Human CD8+ T Cells
201213 citationsauthor #8
T Cells + Dependent Manner in Human CD 8 − STAT3 Lck-Independent MAPK Activation in a IL-21 Can Supplement Suboptimal Kuzushima
20121 citationsauthor #8
Ex Vivo Expansion of Human CD8+ T Cells Using Autologous CD4+ T Cell Help
201236 citationsauthor #12
Endogenous Ligands Selectively Stimulate Highly Avid Autoreactive Human Invariant Natural Killer T Cells with Distinctive T-Cell Receptor Vβ11 CDR3 Sequence Motifs
20112 citationsauthor #5
cells from normal human bone marrow Purification of common acute lymphoblastic leukemia antigen positive
20110 citationsauthor #2
A phase III study of anti-B4-blocked ricin as adjuvant therapy post-autologous bone marrow transplant: CALGB 9254
201125 citationsauthor #8
lymphomas of B-cell and T-cell lineage Expression of common acute lymphoblastic leukemia antigen (CALLA) by
20110 citationsauthor #2
Butler T Cells + CD 8 Educated − Establishment of Antitumor Memory in Humans Using in Vitro
20110 citationsauthor #21
alloantigen Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to
20111 citationsauthor #2
tumor immunity Pivotal role of the B7:CD28 pathway in transplantation tolerance and
20111 citationsauthor #5
chromosomal region 3q13.3-3q21 The gene for B7, a costimulatory signal for T-cell activation, maps to
20111 citationsauthor #6
Induction of HLA-DP4–Restricted Anti-Survivin Th1 and Th2 Responses Using an Artificial Antigen-Presenting Cell
201128 citationsauthor #6
Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.
201150 citationsauthor #6
Aberrant Expression of Functional BAFF-System Receptors by Malignant B-Cell Precursors Impacts Leukemia Cell Survival
201147 citationsauthor #7
Establishment of Antitumor Memory in Humans Using in Vitro–Educated CD8+ T Cells
2011114 citationsauthor #22
Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.
201052 citationsauthor #8
A Series of Human Cell-Based Artificial APC Expands Long-Lived, Th1-Biased, Viral Antigen-Specific CD4+ T Cells with a Central/Effector Memory Phenotpype Restricted by Common HLA-DR Alleles
20100 citationsauthor #9
CD8 Coreceptor-Independent T Cell Stimulation Induces High Avidity CTL In the Presence of IL-21
20100 citationsauthor #7
Alloanergization in haploidentical hematopoietic stem cell transplantation
20100 citationsauthor #2
A panel of human cell-based artificial APC enables the expansion of long-lived antigen-specific CD4+ T cells restricted by prevalent HLA-DR alleles.
201044 citationsauthor #9
Leuprolide Acetate (GnRH Agonist) to Enhance Immune Function Post-Autologous Hematopoietic Stem Cell Transplantation (HSCT)
20100 citationsauthor #3
Human CD4+ T Cells Help CD8+ T Cells Proliferate Ex Vivo by Secreting Both IL-2/IL-21 and Upregulating IL-21R
20100 citationsauthor #12
Combining CD 19 Redirection and Alloanergization to Generate Tumor-Specific Human T Cells for Allogeneic Cell Therapy of B-Cell Malignancies
20103 citationsauthor #8
To Augment A GVL Effect And Reduce GvHD: Alloreactivity Of Human CD19-Specific T Cells Can Be Reduced By Alloanergization Without Reduction Of Tumor-Specific Killing
20090 citationsauthor #5
Delayed Infusion Of Alloanergized Donor Peripheral Blood Mononuclear Cells (PBMC) Augments Pathogen-Specific Immune Reconstitution After T Cell Depleted (TCD) Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) For High-Risk Acute LEUKEMIA/MDS
20090 citationsauthor #11
Artificial APC-Based Generation of IL-21 Secreting CD4+ T Cells That Can Provide Help to CD8+ T Cells.
20090 citationsauthor #6
Immunogenicity of Artificial Dendritic Cells Is Upregulated by ROCK Inhibition-Mediated Dendrite Formation.
20090 citationsauthor #8
Establishing CD8+ T Cell Immunity by Adoptive Transfer of Autologous, IL-15 Expanded, Anti-Tumor CTL with a Central/Effector Memory Phenotype Can Induce Objective Clinical Responses.
20093 citationsauthor #13
Expansion of Allospecific Regulatory T Cells After Anergized, Mismatched Bone Marrow Transplantation
200926 citationsauthor #2
10: Costimulatory Blockade (CSB) During Mixed Lymphocyte Reaction (MLR) Prevents IL27 Upregulation and Signalling
20080 citationsauthor #5
Cyclin D1–Specific Cytotoxic T Lymphocytes Are Present in the Repertoire of Cancer Patients: Implications for Cancer Immunotherapy
200822 citationsauthor #6
High-throughput gene expression profiling of memory differentiation in primary human T cells
200828 citationsauthor #9
42: In vivo Expansion of CD4+FOXP3+ Regulatory T Cells May Contribute to Control of Acute GVHD After HLA-Mismatched Alloanergized HSCT
20081 citationsauthor #4
Alloanergization of HLA-Mismatched Human Donor T Cells Results in the Generation of Allosuppressive CD4 + T Regulatory Cells Both in Vitro and in Vivo
20081 citationsauthor #3
Dissociation of Its Opposing Immunologic Effects Is Critical for the Optimization of Antitumor CD8+ T-Cell Responses Induced by Interleukin 21
200823 citationsauthor #6
38: Alloanergized HLA-Mismatched Bone Marrow Transplantation – Low Incidence of Clinically Significant GVHD and Viral Infection Resulting in Long Term Disease Free Survival
20081 citationsauthor #4
CpG Oligodeoxynucleotides Alter Lymphocyte and Dendritic Cell Trafficking in Humans
200875 citationsauthor #19
Induction of Alloanergy in Human Donor T Cells Without Loss of Pathogen or Tumor Immunity
200823 citationsauthor #3
Phase 1 Clinical Study of Adoptive Immunotherapy with Delayed Infusion of Alloanergized Donor T Cells to Improve Immune Reconstution after Haploidentical Stem Cell Transplantation.
20080 citationsauthor #10
Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies.
200869 citationsauthor #5
Identification of an Evolutionarily Conserved Transcriptional Signature of CD8 Memory Differentiation That Is Shared by T and B Cells1
200877 citationsauthor #17
In Vivo Expansion of CD4+ FOXP3+ Regulatory T Cells May Contribute To Control of Acute GvHD after HLA-Mismatched Alloanergized HSCT.
20072 citationsauthor #4
Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission.
200756 citationsauthor #7
Follicular lymphoma cells stimulated through CD40 can prime alloantigen-specific T cell responses against primary malignant cells
20070 citationsauthor #6
Antigen-presenting function of B-cell precursor malignant cells can be modulated by crosslinking of CD40
20070 citationsauthor #7
Long-Lived Antitumor CD8+ Lymphocytes for Adoptive Therapy Generated Using an Artificial Antigen-Presenting Cell
2007138 citationsauthor #10
A Novel Role for CpG Oligonucleotides in Tumor Immunotherapy: CpG-ODN Induce Targeted Chemokine-Induced Lymphocyte Migration to the Peripheral Tissues in Humans.
20071 citationsauthor #17
Lee Marshall Nadler, MD: A Conversation with the Editor
20073 citationsauthor #1
Myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma at the time of second or subsequent remission: long-term follow-up.
2007223 citationsauthor #2
Costimulatory Blockade (CSB) during Mixed Lymphocyte Reaction (MLR) Prevents IL27 Upregulation and Signalling.
20070 citationsauthor #5
Donor-Derived T Cells Can Be Rendered Hyporesponsive to Alloantigen without Loss of Pathogen or Tumor Immune Responses.
20077 citationsauthor #3
Efficient Presentation of Naturally Processed HLA Class I Peptides by Artificial Antigen-Presenting Cells for the Generation of Effective Antitumor Responses
200640 citationsauthor #7
Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia.
200620 citationsauthor #8
IL-21 secreted by APC confers robust expansion of antigen specific CD8+ T cells with distinct phenotype
20060 citationsauthor #5
Effective Control of Mismatched Alloreactivity Via Ex Vivo Alloantigen-Specific Co-Stimulatory Blockade Does Not Significantly Impact Pathogen-Specific Immunity.
20062 citationsauthor #3
Induction of Alloantigen Specific CD4 T Cell Anergy by B7: CD28 Mediated Costimulatory Blockade Significantly Alters the Functional Program of Bystander CD8, Monocytes, NK and B Cells.
20060 citationsauthor #6
CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants.
200672 citationsauthor #10
Rapid, reliable and inexpensive quality assessment of biotinylated cRNA.
20063 citationsauthor #4
Transcriptional mapping of the anti-viral T cell response shows that impaired memory differentiation causes T cell dysfunction
20060 citationsauthor #7
Leukemia-stimulated bone marrow endothelium promotes leukemia cell survival.
200661 citationsauthor #5
Engagement of CD83 ligand induces prolonged expansion of CD8 (cid:1) T cells and preferential enrichment for antigen speciﬁcity
20062 citationsauthor #8
Long-Term Follow-Up of Autologous Bone Marrow Transplantation for Follicular Lymphoma in First Remission: Bone Marrow Involvement at Harvest and PCR Detectable Disease after Ex Vivo Purging Predict Relapse.
20060 citationsauthor #6
Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity.
2006171 citationsauthor #8
Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species
20060 citationsauthor #6
The N-terminal but not the C-terminal CRD of galectin-8 and the presence of cellular glycosylation are required for the externalization of galectin-8
20060 citationsauthor #4
Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB.
200630 citationsauthor #4
All Memory Lymphocytes Share a Common Differentiation Program.
20060 citationsauthor #12
Gene expression profiling identifies BAX-delta as a novel tumor antigen in acute lymphoblastic leukemia.
200517 citationsauthor #11
Gene Expression Profiling Identifies BAX-δ as a Novel Tumor Antigen in Acute Lymphoblastic Leukemia
200525 citationsauthor #11
Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin's lymphoma.
2005131 citationsauthor #6
Pro-angiogenic Stimulation of Bone Marrow Endothelium Engages mTOR , and Is Inhibited by Simultaneous Blockade of mTOR and NF-κ B
20052 citationsauthor #4
Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation.
20050 citationsauthor #5
Presence of anti‐kinectin and anti‐PMS1 antibodies in Japanese aplastic anaemia patients
200534 citationsauthor #4
Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity.
2005162 citationsauthor #7
Phase I/II Combined Chemoimmunotherapy with Carcinoembryonic Antigen–Derived HLA-A2–Restricted CAP-1 Peptide and Irinotecan, 5-Fluorouracil, and Leucovorin in Patients with Primary Metastatic Colorectal Cancer
200565 citationsauthor #13
Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia.
200550 citationsauthor #14
Long term outcome of patients with mantle cell lymphoma following autologous stem cell transplantation
20050 citationsauthor #4
Patients (Pts) Surviving Haploidentical Stem Cell Transplantation (SCT) after Ex Vivo Costimulatory Blockade To Induce Anergy Experience Few Long-Term Complications.
20053 citationsauthor #4
Identification of a new HLA‐A*0201‐restricted cryptic epitope from CYP1B1
200521 citationsauthor #4
Unexpected Association between Induction of Immunity to the Universal Tumor Antigen CYP1B1 and Response to Next Therapy
2005175 citationsauthor #14
Failure to define window of time for autologous tumor vaccination in patients with newly diagnosed or relapsed acute lymphoblastic leukemia.
200533 citationsauthor #16
Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia.
2005223 citationsauthor #15
Aberrant Expression of BAFF System Molecules on B-Cell Precursor Leukemia Modulates Tumor Cell Survival: Novel Targets for Therapeutic Intervention.
20041 citationsauthor #4
Crosstalk between Breast Cancer Cells and Bone Marrow Endothelium Require the Engagement of PI3K/AKT Signaling.
20040 citationsauthor #4
The T lymphoblastic malignancies
20040 citationsauthor #1
Common gamma chain-signaling cytokines promote proliferation of T-cell acute lymphoblastic leukemia.
200458 citationsauthor #4

TIMELINE

1973 21 citations

1978 0 citations

1979 196 citations

1980 1,636 citations

1981 3,961 citations

1982 572 citations

1983 635 citations

1984 1,291 citations

1985 301 citations

1986 1,067 citations

1987 310 citations

1988 41 citations

1989 722 citations

1990 50 citations

1991 971 citations

1992 891 citations

1993 1,121 citations

1994 1,956 citations

1995 1,119 citations

1996 793 citations

1997 617 citations

1998 324 citations

1999 903 citations

2000 525 citations

2001 530 citations

2002 625 citations

2003 370 citations

2004 798 citations

2005 941 citations

2006 401 citations

2007 430 citations

2008 320 citations

2009 29 citations

2010 99 citations

2011 269 citations

2012 72 citations

2013 1 citations

2014 25 citations

2018 9 citations

Unknown 161 citations

L. Nadler

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