L. Harker

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Aliases
La Harker, L. Harker, Lawrence Harker, Lawrence A. Harker, L.a. Harker, Laurence A. Harker, Laurence Harker, Laurence A Harker, Laurence Minnesot A. C. O. Harker, L Harker, L. A. Harker, Lawrence A Harker, L A Harker
Publication record
310 papers · 28,563 citations · H-index 70

PAPERS

OF INHIBITING PLATELET DEPENDENT ARTERAL THROMBOSIS Inventors :
20170 citationsauthor #1
Growth and Development Factor Megakaryocyte Immunodeficiency Virus by Pegylated Recombinant Human Treatment of Thrombocytopenia in Chimpanzees Infected With Human
20130 citationsauthor #4
Platelet and fibrinogen kinetic evaluation of thrombogenesis.
20094 citationsauthor #1
Pathogenesis of Arterial Vascular Disease
200835 citationsauthor #1
Factors influencing platelet consumption by polyacrylamide hydrogels
20069 citationsauthor #2
Atherogenlc Diet Mixture and Control Diet Ingredient Atherogenic diet Casein , USP Lactalbumin Wheat flour Dextrin Sucrose
20050 citationsauthor #3
Drug Siastic Tubing Silastic Adhesive Dacron Graft Porous Teflon Drug Concentration Graft Boundary Layer
20050 citationsauthor #4
Anticoagulants and Thrombolytic Agents in Cardiovascular Disease 'ombosis: Its Role Prevention in rdiovascuIar 3,nts Part
20050 citationsauthor #1
PLATELETS AND VASCULAR OCCLUSION: PHARMACOLOGY OF PLATELET INHIBITION
20050 citationsauthor #1
Heparin-Resistant Thrombus Formation by Endovascular Stents
20050 citationsauthor #6
Contributions Regulation of Platelet-Derived Growth Factor Ligand and Receptor Gene Expression by a-Thrombin in Vascular Smooth Muscle Cells
20050 citationsauthor #3
Concepts of Thrombogenesis and Its Prevention ombosis: Its Role Prevention in diovascular )nts Part
20050 citationsauthor #1
CLOFIBRATE THERAPY IN HYPERLIPOPROTEINEMIA / Harker and Hazzard bound 125 I . Fibrinogen survival ( the average time in
20050 citationsauthor #1
Effects of Aspirin 0130 BLEEDING COMPLICATIONS IN TREATMENT WITH ASA AND ANTICOAGULANTS
200513 citationsauthor #27
Platelet-active drugs: the relationships among dose, effectiveness, and side effects.
20041,005 citationsauthor #6
Preparation and Storage of Platelet Concentrates
2003183 citationsauthor #2
A Protocol for Cryoprecipitate Production
200315 citationsauthor #2
Cardiovascular Biomaterials and Biocompatibility
20022 citationsauthor #1
The sensitivity of indicators of thrombosis initiation to a bileaflet prosthesis leakage stimulus.
200122 citationsauthor #7
Thrombogenesis in sickle cell disease.
2001223 citationsauthor #2
Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers.
2000213 citationsauthor #1
Comparative Safety and Tolerability of Clopidogrel and Aspirin
1999148 citationsauthor #1
Anticoagulant Therapy with Warfarin for Thrombotic Disorders
19990 citationsauthor #1
Leakage flow through mechanical prostheses: an initiator of platelet damage
19990 citationsauthor #6
Reduction in vascular lesion formation by hirudin secreted from retrovirus-transduced confluent endothelial cells on vascular grafts in baboons.
199911 citationsauthor #7
Platelet growth factors: potential impact on transfusion medicine
199920 citationsauthor #3
Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates.
1998136 citationsauthor #1
Therapeutic Inhibition of Platelet Function in Stroke
199845 citationsauthor #1
Effective and efficient platelet transfusion strategies that maintain hemostatic protection
199816 citationsauthor #1
Local delivery of 125l-labeled ReoPro to baboon brachial arteries using an iontophoretic balloon catheter
19980 citationsauthor #9
Platelet-Active Drugs
1998157 citationsauthor #6
Ineffective platelet production in thrombocytopenic human immunodeficiency virus-infected patients.
1998111 citationsauthor #9
Effects of mpl ligands on platelet production and function in nonhuman primates
19982 citationsauthor #1
Platelets in thrombotic disorders: quantitative and qualitative platelet disorders predisposing to arterial thrombosis.
199811 citationsauthor #1
Treatment of Thrombocytopenia in Chimpanzees Infected With Human Immunodeficiency Virus by Pegylated Recombinant Human Megakaryocyte Growth and Development Factor
19987 citationsauthor #1
S28 Clopidogrel benefits over aspirin in patients with coronary disease
19980 citationsauthor #1
In Vivo Dose—Response Effects of Mpl Ligands on Platelet Production and Function
19975 citationsauthor #1
Identification of Dysfunctional Endothelial Cells over Vascular Lesions in the Non‐Human Primate a
19973 citationsauthor #4
Hemodialysis access graft stenosis: percutaneous transluminal angioplasty.
19979 citationsauthor #4
In Vitro Effects of Mpl Ligands on Platelet Function
19972 citationsauthor #1
Effects of polyethylene glycol-conjugated recombinant human megakaryocyte growth and development factor on platelet counts after chemotherapy for lung cancer.
1997275 citationsauthor #10
Anti-VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates.
199720 citationsauthor #6
Prevention of thrombocytopenia and neutropenia in a nonhuman primate model of marrow suppressive chemotherapy by combining pegylated recombinant human megakaryocyte growth and development factor and recombinant human granulocyte colony-stimulating factor.
199746 citationsauthor #1
Antithrombotic Strategies Targeting Thrombin Activities, Thrombin Receptors and Thrombin Generation
199770 citationsauthor #1
Reduction in stent and vascular graft thrombosis and enhancement of thrombolysis by recombinant Lys-plasminogen in nonhuman primates.
199711 citationsauthor #8
The role of platelets in the early and late vascular responses initiated by mechanical vascular injury
199712 citationsauthor #1
Relative benefits and risks of new antithrombotic agents
19960 citationsauthor #1
Distribution and severity of stenoses in functioning arteriovenous grafts: A duplex and angiographic study
199633 citationsauthor #6
Enhanced in vivo antithrombotic effects of endothelial cells expressing recombinant plasminogen activators transduced with retroviral vectors.
1996106 citationsauthor #5
Heparin coating dramatically reduces platelet deposition on incompletely deployed Palmaz-Schatz™ in the baboon A-V shunt
19964 citationsauthor #8
MECHANICAL VALVES. AUTHORS' REPLY
199615 citationsauthor #3
Neointima formation in stented baboon carotid arteries is reduced by bonded heparin: Correlation with decreased thrombogenicity
19963 citationsauthor #7
Measurements of In Vivo Megakaryocytopoiesis: Studies in Nonhuman Primates and Patients
199618 citationsauthor #2
Subject Index, Vol. 26 (suppl 1), 1996
19961 citationsauthor #34
Mechanical valves.
199614 citationsauthor #3
Antithrombotic and antilesion benefits without hemorrhagic risks by inhibiting tissue factor pathway.
199680 citationsauthor #1
Host Reactions to Biomaterials and Their Evaluation
1996125 citationsauthor #4
Preclinical studies and potential clinical applications of c‐mpl ligand
19965 citationsauthor #2
Exaggerated platelet reactivity in major depression.
1996573 citationsauthor #8
Heparin coated Palmaz-Schatz™ stents are highly thrombo-resistant: A baboon A-V shunt study
19968 citationsauthor #7
Title Page / Table of Contents, Vol. 26, Supplement 1, 1996
19960 citationsauthor #34
Enhanced thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons.
199654 citationsauthor #2
123. The endothelium and hemostatic control
19960 citationsauthor #1
Antithrombotic Benefits and Hemorrhagic Risks of Direct Thrombin Antagonists
199564 citationsauthor #1
Hemostasis and Cardiopulmonary Bypass
199520 citationsauthor #3
A device for local administration of a drug
19950 citationsauthor #4
Dispositif d'apport localise d'un medicament
19950 citationsauthor #2
Thrombin hypothesis of thrombus generation and vascular lesion formation.
1995122 citationsauthor #1
Comparison of the thrombogenicity of stainless steel and tantalum coronary stents.
199549 citationsauthor #7
Device localized delivery of a drug.
19950 citationsauthor #2
Strategies for inhibiting the effects of thrombin
199418 citationsauthor #1
Relative antithrombotic effects of monoclonal antibodies targeting different platelet glycoprotein-adhesive molecule interactions in nonhuman primates.
199470 citationsauthor #8
5 Platelet factors predisposing to arterial thrombosis
199414 citationsauthor #1
Characterization of thrombin receptor expression during vascular lesion formation.
1994142 citationsauthor #12
New Antithrombotic Strategies for Resistant Thrombotic Processes
199419 citationsauthor #1
Local delivery of an antithrombin inhibits platelet-dependent thrombosis.
199443 citationsauthor #4
Thrombosis/antithrombotic therapy. The role of thrombin in vascular lesion formation in nonhuman primates
19941 citationsauthor #1
Transient Ischemic Attacks in Baboons due to Platelet Microemboli1
19940 citationsauthor #5
Platelet factors predisposing to arterial thrombosis.
199412 citationsauthor #1
Platelets and vascular thrombosis.
199436 citationsauthor #1
Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
19943,783 citationsauthor #369
Dermatan sulfate inhibition of fibrin-rich thrombus formation in nonhuman primates.
199310 citationsauthor #3
Antithrombotic Effects of Synthetic Pentasaccharide with High Affinity for Plasma Antithrombin III in Non-Human Primates
199344 citationsauthor #3
Lasting safe interruption of endarterectomy thrombosis by transiently infused antithrombin peptide D-Phe-Pro-ArgCH2Cl in baboons.
199338 citationsauthor #7
Interruption of vascular thrombosis by bolus anti-platelet glycoprotein IIb/IIIa monoclonal antibodies in baboons.
199315 citationsauthor #5
Interruption of Vascular Thrombus Formation and Vascular Lesion Formation by Dietary n‐3 Fatt Acids in Fish Oil in Nonhuman Primates
1993117 citationsauthor #1
Ticlopidine’s Mechanism of Action on Human Platelets
199330 citationsauthor #1
Use of antiplatelet agents in the management of thrombotic disorders.
19932 citationsauthor #1
4 Mechanism of Action on Human Platelets
19930 citationsauthor #1
Exteriorized chronic aorto-caval arteriovenous access shunts in the baboon (Papio cynocephalus).
19934 citationsauthor #7
Induced anticoagulant therapy by endogenous activated protein C (APC)
19920 citationsauthor #2
Induction of Transient Neurological Dysfunction in Baboons by Platelet Microemboli
199231 citationsauthor #7
Aspirin Plus Dipyridamole: Not-So-Dynamic Buo
19920 citationsauthor #1
What are the effects of dietary n-3 fatty acids on vascular thrombus and lesion formation in nonhuman primates?
19920 citationsauthor #1
Antihemostatic and antithrombotic effects of monoclonal antibodies against von Willebrand factor in nonhuman primates.
199213 citationsauthor #5
Failure of Aspirin plus Dipyridamole To Prevent Restenosis after Carotid Endarterectomy
199233 citationsauthor #1
Regulation of platelet-derived growth factor ligand and receptor gene expression by alpha-thrombin in vascular smooth muscle cells.
1992115 citationsauthor #3
Production of transient ischaemic events by platelet emboli in baboons.
19924 citationsauthor #5
Starting Aspirin Therapy After Operation: Effects on Early Graft Patency
1991186 citationsauthor #27
Experimental arterial thrombosis in nonhuman primates.
199170 citationsauthor #1

TIMELINE

1953 0 citations

1968 269 citations

1969 665 citations

1970 857 citations

1971 74 citations

1972 1,022 citations

1973 57 citations

1974 2,957 citations

1975 169 citations

1976 2,628 citations

1977 1,126 citations

1978 404 citations

1979 412 citations

1980 1,867 citations

1981 499 citations

1982 532 citations

1983 592 citations

1984 1,987 citations

1985 165 citations

1986 645 citations

1987 235 citations

1988 864 citations

1989 509 citations

1990 668 citations

1991 603 citations

1992 196 citations

1993 260 citations

1994 4,138 citations

1995 255 citations

1996 1,039 citations

1997 453 citations

1998 485 citations

1999 179 citations

2000 213 citations

2001 245 citations

2002 2 citations

2003 198 citations

2004 1,005 citations

2005 13 citations

2006 9 citations

2008 35 citations

2009 4 citations

2013 0 citations

2017 0 citations

Unknown 1 citations

L. Harker

PROFILE

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