P. Brubaker

A New Role for Endocrine Cells in the Intestinal Crypt
20231 citationsauthor #1
Thank you to all of our reviewers in 2021
20220 citationsauthor #21
The molecular determinants of glucagon-like peptide secretion by the intestinal L-cell.
202210 citationsauthor #1
The cytoskeletal transport protein, secretagogin, is essential for diurnal glucagon-like peptide-1 secretion in mice.
20223 citationsauthor #5
Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion
202212 citationsauthor #4
Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells
202217 citationsauthor #6
Disrupted and elevated circadian secretion of glucagon-like peptide-1 in a murine model of type 2 diabetes.
20227 citationsauthor #5
The intestine and the microbiota in maternal glucose homeostasis during pregnancy
202211 citationsauthor #2
Diurnal changes in the murine small intestine are disrupted by obesogenic Western Diet feeding and microbial dysbiosis
20218 citationsauthor #6
The discovery of insulin revisited: lessons for the modern era.
202151 citationsauthor #2
Effects of Obesogenic Feeding and Free Fatty Acids on Circadian Secretion of Metabolic Hormones: Implications for the Development of Type 2 Diabetes
20216 citationsauthor #2
1193-P: Investigating the Role of Intestinal L-Cell Secretagogin in Circadian GLP-1 Secretion in a Mouse Model of Type 2 Diabetes
20210 citationsauthor #2
L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis
20218 citationsauthor #5
260-OR: The L-Cell Clock Is Required for Circadian GLP-1 Secretion and Maintenance of Intestinal Homeostasis
20210 citationsauthor #4
Complementary and antagonistic effects of combined glucagon-like peptide-2 and glucagon-like peptide-1 receptor agonist administration on parameters relevant to short bowel syndrome.
20218 citationsauthor #3
Metabolic homeostasis: it's all in the timing.
20219 citationsauthor #1
Thank you to all of our reviewers in 2020
20210 citationsauthor #21
Sa118 THE ROLE OF LGR5+ STEM CELLS IN GLUCAGON-LIKE PEPTIDE-2 INDUCED INTESTINAL PROLIFERATION
20210 citationsauthor #2
Why Recycling Matters: Glucagon-Like Peptide-2 and the Regulation of Intestinal Sodium and Fluid Absorption
20200 citationsauthor #1
Requirement for the intestinal epithelial insulin‐like growth factor‐1 receptor in the intestinal responses to glucagon‐like peptide‐2 and dietary fat
20207 citationsauthor #4
In the Short-term, Milk Fat Globule Epidermal Growth Factor-8 Causes Site-specific Intestinal Growth in Resected Piglets
20201 citationsauthor #7
Circadian GLP-1 Secretion in Mice Is Dependent on the Intestinal Microbiome for Maintenance of Diurnal Metabolic Homeostasis
202040 citationsauthor #9
Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion
202030 citationsauthor #8
Inflaming the Clock: Effects of Interleukin 1β on Circadian Rhythmicity of Pancreatic β Cells
20201 citationsauthor #2
Dietary Cyanidin-3-Glucoside Attenuates High-Fat-Diet-Induced Body-Weight Gain and Impairment of Glucose Tolerance in Mice via Effects on the Hepatic Hormone FGF21.
202026 citationsauthor #8
Durability of linear small intestinal growth following treatment discontinuation of long-acting glucagon-like peptide-2 (GLP-2) analogues.
20202 citationsauthor #5
Site-Specific and Temporal Effects of Apraglutide, a Novel Long-Acting Glucagon-Like Peptide-2 Receptor Agonist, on Intestinal Growth in Mice
202011 citationsauthor #5
Analysis of Western diet, palmitate and BMAL1 regulation of neuropeptide Y expression in the murine hypothalamus and BMAL1 knockout cell models.
202026 citationsauthor #5
GLP-2, EGF and the intestinal epithelial IGF-1 receptor interactions in the regulation of crypt cell proliferation.
202024 citationsauthor #3
Circadian rhythms and the gastrointestinal tract: relationship to metabolism and gut hormones.
202039 citationsauthor #4
The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1
201939 citationsauthor #14
SUN-LB018 Role of BMAL1 in Western Diet-Induced Disruption of Circadian Hypothalamic Feeding Neuropeptides
20190 citationsauthor #4
The roles of glucagon-like peptide-2 and the intestinal epithelial insulin-like growth factor-1 receptor in regulating microvillus length
201928 citationsauthor #2
524 – Epidermal Growth Factor Improves Glucagon-Like Peptide-2-Mediated Growth in the Intestine of Mice in an Insulin-Like Growth Factor-1 Receptor-Independent Manner
20190 citationsauthor #4
Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum.
201936 citationsauthor #6
307 – Proteomic Analysis of Intestinal Brush Border Membranes from Intestinal Epithelial Insulin-Like Growth Factor-1 Receptor Knockout Mice with and Without Chronic Glucagon-Like Peptide-2 Treatment
20190 citationsauthor #2
Essential role of Munc18-1 in the regulation of glucagon-like peptide-1 secretion
20194 citationsauthor #8
33 - Connection Between Lipid Absorption and the Intestinal Epithelial Insulin-Like Growth Factor-1 Receptor
20180 citationsauthor #2
The Cardiac Glucagonlike Peptide-1 Receptor: Whither Art Thou?
20180 citationsauthor #1
Linking the Gut Microbiome to Metabolism Through Endocrine Hormones.
20189 citationsauthor #1
Glucagon-like Peptide-2 and the Regulation of Intestinal Growth and Function.
201892 citationsauthor #1
Comment on Ussar et al. Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor. Diabetes 2017;66:886–896
20171 citationsauthor #1
The SNARE Protein Syntaxin-1a Plays an Essential Role in Biphasic Exocytosis of the Incretin Hormone Glucagon-Like Peptide 1
201735 citationsauthor #10
Role and Regulation of Insulin-Like Growth Factor Binding Protein-4 in the Rodent Intestine
20170 citationsauthor #4
Synergy of glucagon-like peptide-2 and epidermal growth factor coadministration on intestinal adaptation in neonatal piglets with short bowel syndrome.
201729 citationsauthor #10
Translational Human Pathophysiology Synergy of glucagon-like peptide-2 and epidermal growth factor coadministration on intestinal adaptation in neonatal piglets with short bowel syndrome
20170 citationsauthor #10
Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function
20178 citationsauthor #8
Species-Dependent Mechanisms Regulating Glucose-Dependent GLP-1 Secretion?
20173 citationsauthor #1
Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors
20176 citationsauthor #10
Current and potential therapeutic targets of glucagon-like peptide-2.
201625 citationsauthor #3
Short-term sleep deprivation with nocturnal light exposure alters time-dependent glucagon-like peptide-1 and insulin secretion in male volunteers.
201689 citationsauthor #6
High-Fat Diet and Palmitate Alter the Rhythmic Secretion of Glucagon-Like Peptide-1 by the Rodent L-cell.
201653 citationsauthor #4
The Endocrine Society Centennial: Cleavage Matters.
20160 citationsauthor #1
Glucagon-Like Peptide-2 Requires a Full Complement of Bmi-1 for Its Proliferative Effects in the Murine Small Intestine.
20168 citationsauthor #3
Su1770 Insulin-Like Growth Factor Binding Protein-4 Inhibits Intestinal Epithelial Proliferation
20160 citationsauthor #3
40th EASD Annual Meeting of the European Association for the Study of Diabetes
201626 citationsauthor #492
Su1776 Microvillus Structure and Function Modulated by Glucagon-like Peptide-2 and the Intestinal Epithelial Insulin-like Growth Factor-1 Receptor
20160 citationsauthor #3
Glucagon‐like peptide‐1: The missing link in the metabolic clock?
201628 citationsauthor #1
On the horizon: trophic peptide growth factors as therapy for neonatal short bowel syndrome
20168 citationsauthor #5
Murine GLUTag Cells
20157 citationsauthor #2
673 Novel Role of the Insulin-Like Growth Factor-1 Receptor in Regulating Murine Intestinal Microvillus Structure and Fat Absorption
20150 citationsauthor #4
190 The Stimulation of Quiescent Stem Cells by Glucagon-Like Peptide-2 (GLP-2) in the Murine Small Intestine
20150 citationsauthor #3
Glucagon-Like Peptide-2 Therapy Augments Intestinal Adaptation in a Preclinical Model of Neonatal Short Bowel Syndrome with Distal Intestinal Resection
20150 citationsauthor #3
GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7.
2015116 citationsauthor #8
Chronic Exposure to TNFα Impairs Secretion of Glucagon-Like Peptide-1.
201542 citationsauthor #7
Metformin improves intestinal L cell survival in vitro and in vivo
20150 citationsauthor #2
IGF binding protein-4 is required for the growth effects of glucagon-like peptide-2 in murine intestine.
201522 citationsauthor #4
Exogenous glucagon-like peptide-2 improves outcomes of intestinal adaptation in a distal-intestinal resection neonatal piglet model of short bowel syndrome
201432 citationsauthor #8
Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell
201434 citationsauthor #4
660 Insulin-Like Growth Factor Binding Protein-4 Is Required for the Growth Effects of Glucagon-Like Peptide-2 in Murine Intestine
20140 citationsauthor #4
Circadian Secretion of the Intestinal Hormone GLP-1 by the Rodent L Cell
2014113 citationsauthor #5
Corticotropin-releasing hormone and the sympathoadrenal system are major mediators in the effects of peripherally administered exendin-4 on the hypothalamic-pituitary-adrenal axis of male rats.
201424 citationsauthor #6
Gut hormones fulfill their destiny: from basic physiology to the clinic.
20143 citationsauthor #1
R-spondin1 Deficiency Enhances &bgr;-Cell Neogenesis in a Murine Model of Diabetes
20145 citationsauthor #4
The intestinal epithelial insulin-like growth factor-1 receptor links glucagon-like peptide-2 action to gut barrier function.
2014102 citationsauthor #9
Ghrelin Is a Novel Regulator of GLP-1 Secretion
201497 citationsauthor #4
Effects of prolonged exendin-4 administration on hypothalamic-pituitary-adrenal axis activity and water balance.
201329 citationsauthor #5
Glucagon‐like Peptide‐2 Therapy Improves Outcomes of Intestinal Adaptation and Decreases Relative Apoptosis in a Distal Intestinal Resection Neonatal Piglet Model of Short Bowel Syndrome
20130 citationsauthor #5
697 Role of the Intestinal Epithelial-Insulin-Like Growth Factor-1 Receptor in Glucagon-Like Peptide-2-Mediated Enhancement of Intestinal Barrier Function
20130 citationsauthor #5
Hypothalamic-Pituitary-Adrenal axis activity and water
20131 citationsauthor #5
From Diarrhea to Obesity in Prohormone Convertase 1/3 Deficiency: Age-dependent Clinical, Pathologic, and Enteroendocrine Characteristics
201338 citationsauthor #5
Glucagon-like peptide-2 increases dysplasia in rodent models of colon cancer.
201246 citationsauthor #4
Novel biological action of the dipeptidylpeptidase-IV inhibitor, sitagliptin, as a glucagon-like peptide-1 secretagogue.
201246 citationsauthor #6
Role of fatty acid transport protein 4 in oleic acid-induced glucagon-like peptide-1 secretion from murine intestinal L cells.
201252 citationsauthor #6
Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis
201246 citationsauthor #2
Canadian Surgery Forum.
20123 citationsauthor #102
A beautiful cell (or two or three?).
201219 citationsauthor #1
Intestinal Epithelial Insulin-Like Growth Factor-1 Receptor Mediates Chronic Glucagon-Like Peptide-2-Induced Epithelial Proliferation and Associated Growth of the Crypt-Villus Unit
20110 citationsauthor #4
Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts.
201166 citationsauthor #11
Essential role for protein kinase Cζ in oleic acid-induced glucagon-like peptide-1 secretion in vivo in the rat.
201150 citationsauthor #5
Glucagon-Like Peptide-2 Receptor Antagonism Decreases Carcinogenesis in Murine Colitis-Associated Cancer
20110 citationsauthor #4
Loss of glucagon-like peptide-2-induced proliferation following intestinal epithelial insulin-like growth factor-1-receptor deletion.
201183 citationsauthor #7
Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell.
2011161 citationsauthor #6
The "cryptic" mechanism of action of glucagon-like peptide-2.
2011146 citationsauthor #2
R-SPONDIN-1 IS A NOVEL β -CELL GROWTH FACTOR AND INSULIN SECRETAGOGUE
20100 citationsauthor #4
Minireview: update on incretin biology: focus on glucagon-like peptide-1.
2010125 citationsauthor #1
R-spondin-1 Is a Novel β-Cell Growth Factor and Insulin Secretagogue*
201033 citationsauthor #4
S1688 Glucagon-Like Peptide-2 Increases Colonic Dysplasia in Rats Treated With the Dietary Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]Pyridine (Phip)
20100 citationsauthor #2
Proceedings of a Symposium to Honour Mladen Vranic for a Lifetime of Scientific Achievements and Mentoring
20100 citationsauthor #1
From Enteroglucagon to the Glucagon-Like Peptides, GLP-1 and GLP-2
20100 citationsauthor #1

PROFILE

PAPERS

TIMELINE

COAUTHOR MAP

CONCEPT FOOTPRINT