D. Radzioch

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Aliases
D Radzioch, D. Radzioch, Danuta Radzioch
Publication record
212 papers · 8,033 citations · H-index 50

PAPERS

Western Blotting with Fast SDS‐PAGE and Semi‐Dry Protein Transfer
20235 citationsauthor #4
Abstract 2329: Disulfiram metabolite modulates NK and T cell cytotoxicity against metastatic colorectal cancer through tumor derived NKG2D ligands
20230 citationsauthor #14
One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy
202212 citationsauthor #9
WS05.06 Novel high-throughput screening tool for monitoring CFTR levels and localisation in cytoplasm membrane with luminescent peptide tag
20220 citationsauthor #8
168 Results from APPLAUD phase 2 study with pro-resolution drug candidate LAU-7b in adults with cystic fibrosis
20220 citationsauthor #12
The gradient-like separation and reduced running time with Tris-Tricine-HEPES buffer for SDS-PAGE.
20227 citationsauthor #4
668 CRISPR-based cellular models with endogenous expression of HiBiT-tagged wild-type and mutant cystic fibrosis transmembrane conductance regulator enables high-throughput biology studies and screening for new transporter modulators
20220 citationsauthor #6
Oral Covid-19 Antiviral Candidate LAU-7b Demonstrates 100% Reduction of the Risk of Progression to Mechanical Ventilation and Death in Hospitalized Moderate-to-Severe Covid-19 Patients
20221 citationsauthor #13
Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease
20224 citationsauthor #15
Characterization of skeletal muscle wasting pathways in diaphragm and limb muscles of cystic fibrosis mice.
20228 citationsauthor #7
657 Combinatory treatment of LAU-7b with triple therapy results in improved lung physiology and restored fatty acid and lipid levels
20220 citationsauthor #15
678: Design and validation of luminescent HTS tool for discovery and optimization of novel combination of CFTR correctors and modifiers
20210 citationsauthor #8
CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells
202139 citationsauthor #12
LasR-deficient Pseudomonas aeruginosa variants increase airway epithelial mICAM-1 expression and enhance neutrophilic lung inflammation
202128 citationsauthor #8
Abstract 1251: Dithiocarb-copper complex, CuET, demonstrates anti-neoplastic activity in mouse model of prostate cancer and prevents recurrence of tumors
20210 citationsauthor #8
Editorial: Quo Vadis Lipid Mediators – Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases
20212 citationsauthor #1
627: Investigation of pharmacological correction of F508del-CFTR protein during chronic infections
20210 citationsauthor #9
The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide
202011 citationsauthor #5
Efficacy of Optimized Treatment Protocol Using LAU-7b Formulation against Ovalbumin (OVA) and House Dust Mite (HDM) -Induced Allergic Asthma in Atopic Hyperresponsive A/J Mice
20209 citationsauthor #6
Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction.
202011 citationsauthor #11
Computed Tomography of the Thorax to Determine Diaphragm and Non-Respiratory Muscle Characteristics in Patients with Cystic Fibrosis
20200 citationsauthor #5
Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis
20208 citationsauthor #7
A brief overview of cancer research in the elderly population
20200 citationsauthor #11
Abstract 5246: Disulfiram anticancer metabolite, dithiocarb-copper complex, demonstrates anti-neoplastic activity against hypermutated colorectal cancers
20200 citationsauthor #8
Importance of miRNA in SARS-CoV2 infection
20208 citationsauthor #6
Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults
20206 citationsauthor #3
Treatment of Allergic Asthma with Fenretinide Formulation (LAU-7b) Downregulates ORMDL Sphingolipid Biosynthesis Regulator 3 (Ormdl3) Expression and Normalizes Ceramide Imbalance
20204 citationsauthor #7
In Vivo Susceptibility of Cystic Fibrosis Mice to Inflammation-Induced Diaphragm and Limb Muscle Dysfunction
20190 citationsauthor #4
Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain.
20194 citationsauthor #5
Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain.
201936 citationsauthor #5
Depletion of BAFF cytokine exacerbates infection in Pseudomonas aeruginosa infected mice.
20196 citationsauthor #8
Loss of the zona pellucida-binding protein 2 (Zpbp2) gene in mice impacts airway hypersensitivity and lung lipid metabolism in a sex-dependent fashion
20180 citationsauthor #10
Toll‐Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris suum‐induced Allergic Asthma in Nonhuman Primates
20187 citationsauthor #16
Loss of the zona pellucida-binding protein 2 (Zpbp2) gene in mice impacts airway hypersensitivity and lung lipid metabolism in a sex-dependent fashion
20189 citationsauthor #10
c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages
20189 citationsauthor #5
Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside
201739 citationsauthor #10
A prognostic model for development of significant liver fibrosis in HIV-hepatitis C co-infection
20178 citationsauthor #6
Mouse Chromosome 4 Is Associated with the Baseline and Allergic IgE Phenotypes
20171 citationsauthor #6
LUNG INFLAMMATION IN F508DEL CFTR MICE, PARTIAL CORRECTION BY THE SPHINGOSINE-1-PHOSPHATE LYASE INHIBITOR LX2931
20160 citationsauthor #3
New Frontiers in Cancer Chemotherapy — Targeting Cell Death Pathways
201611 citationsauthor #3
Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions
2016908 citationsauthor #18
C-Reactive Protein in Stable Cystic Fibrosis: An Additional Indicator of Clinical Disease Activity and Risk of Future Pulmonary Exacerbations
201622 citationsauthor #11
Importance of characterization of variation in the secondary endpoint measures prior to the trial: A key to a successful outcome of phase 1 trial and progression to a phase 2 stage of the study
20160 citationsauthor #1
Genetics of Allergic Asthma and Current Perspectives on Therapeutic Management
20164 citationsauthor #4
Allergic Asthma: A Summary from Genetic Basis, Mouse Studies, to Diagnosis and Treatment.
20166 citationsauthor #2
AllerGen’s 8th research conference
20160 citationsauthor #66
Evolution of the Immune Response to Chronic Airway Colonization with Aspergillus fumigatus Hyphae
201533 citationsauthor #12
Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses
2015115 citationsauthor #5
Assessment of chloroquine as a modulator of immune activation to improve CD4 recovery in immune nonresponding HIV‐infected patients receiving antiretroviral therapy
201560 citationsauthor #5
Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection.
2015123 citationsauthor #10
Running title : Murine model of Aspergillus colonization 1 2 Title : The evolution of the immune response to chronic airway colonization with Aspergillus 3 fumigatus hyphae
20150 citationsauthor #13
Clinical outcomes associated with Staphylococcus aureus and Pseudomonas aeruginosa airway infections in adult cystic fibrosis patients
201577 citationsauthor #6
ZRBA1, a Mixed EGFR/DNA Targeting Molecule, Potentiates Radiation Response Through Delayed DNA Damage Repair Process in a Triple Negative Breast Cancer Model.
201516 citationsauthor #5
Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers
201418 citationsauthor #5
Fenretinide prevents inflammation and airway hyperresponsiveness in a mouse model of allergic asthma.
201424 citationsauthor #8
Candidate Markers Associated with the Probability of Future Pulmonary Exacerbations in Cystic Fibrosis Patients
201450 citationsauthor #13
Deregulated Balance of Omega-6 and Omega-3 Polyunsaturated Fatty Acids following Infection by the Zoonotic Pathogen Streptococcus suis
201419 citationsauthor #6
Mapping of a Chromosome 12 Region Associated with Airway Hyperresponsiveness in a Recombinant Congenic Mouse Strain and Selection of Potential Candidate Genes by Expression and Sequence Variation Analyses
20144 citationsauthor #8
Mapping of novel chromosomal regions associated with atopy
20140 citationsauthor #7
IDO-induced immunosuppressive tryptophan catabolism following primary HIV infection
20141 citationsauthor #5
A New Era of Targeting the Ancient Gatekeepers of the Immune System: Toll-Like Agonists in the Treatment of Allergic Rhinitis and Asthma
201493 citationsauthor #3
143: Potentiation of radiation response by a novel EGFR/DNA targeting molecule in a triple negative breast cancer model
20140 citationsauthor #6
Effect of lycopene administration on oxidative stress markers in blood plasma in cysic fibrosis patients
20130 citationsauthor #5
Chromatin Remodelling During Host-Bacterial Pathogen Interaction
201311 citationsauthor #3
Induction of nitric oxide synthase expression by lipopolysaccharide is mediated by calcium-dependent PKCα-β1 in alveolar epithelial cells.
201313 citationsauthor #6
Promoter deletion analysis using a dual-luciferase reporter system.
201345 citationsauthor #4
Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy.
201324 citationsauthor #9
Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses
201320 citationsauthor #13
University of Groningen Distinct Tryptophan Catabolism and Th 17 / Treg Balance in HIV Progressors and Elite
20130 citationsauthor #5
EGFR/DNA Targeting Molecule Potentiates Radiation Response in a Murine Breast Cancer Model
20130 citationsauthor #6
Soluble CD40 Ligand Plays an Immunosuppressive Role in HIV Infection via IDO-Induced Tryptophan Catabolism, Treg Expansion and Microbial Translocation
20130 citationsauthor #5
Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers
201382 citationsauthor #5
ModelDevelopment in a Murine Asthma Protein Tyrosine Phosphatases Regulate
20130 citationsauthor #3
TLR4-Dependent Responses to Endogenous, Selective Disadvantage: Genetic Evidence for TLR4-Deficient Macrophages Imposes a Abrupt Expression of TLR4 in
20130 citationsauthor #5
Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway
201317 citationsauthor #6
Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model
201217 citationsauthor #7
Combination of Ionizing Radiation and DNA/EGFR Binary Targeting Molecule Delays DNA Double-Strands Repair
20120 citationsauthor #5
Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis
201258 citationsauthor #14
Exploring Secrets of Nuclear Actin Involvement in the Regulation of Gene Transcription and Genome Organization
20124 citationsauthor #3
A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas
201253 citationsauthor #11
Polymorphisms in TOLL-like receptor genes and their roles in allergic asthma and atopy.
201115 citationsauthor #4
Recruitment of SWI/SNF Complex Is Required for Transcriptional Activation of the SLC11A1 Gene during Macrophage Differentiation of HL-60 Cells*
201132 citationsauthor #4
Secretory Leukocyte Protease Inhibitor Plays an Important Role in the Regulation of Allergic Asthma in Mice
201144 citationsauthor #10
Distinct Functions of the Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinases MK2 and MK3
201166 citationsauthor #8
Fragile X Related Protein 1 Clusters with Ribosomes and Messenger RNAs at a Subset of Dendritic Spines in the Mouse Hippocampus
201133 citationsauthor #4
Abstract 2506: Preclinical evaluation of sorafenib in combination with ionizing radiation in metastatic breast cancer model
20110 citationsauthor #7
Brg-1 mediates the constitutive and fenretinide-induced expression of SPARC in mammary carcinoma cells via its interaction with transcription factor Sp1
201013 citationsauthor #6
Clinical Relevance of KRAS in Human Cancers
2010386 citationsauthor #3
Fenretinide Promotes Functional Recovery and Tissue Protection after Spinal Cord Contusion Injury in Mice
201071 citationsauthor #8
The protective effect of fenretinide against allergic asthma
20100 citationsauthor #4
Immunoregulatory role of secretory leukocyte protease inhibitor in allergic asthma
20102 citationsauthor #9
MAPKAPK-2 signaling is critical for cutaneous wound healing.
201060 citationsauthor #8
Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury.
201063 citationsauthor #8
Identification of novel chromosomal regions associated with airway hyperresponsiveness in recombinant congenic strains of mice
201015 citationsauthor #7
Combination of Sorafenib with Ionizing Radiation Induces G2/M Cell Cycle Arrest in Breast Cancer Cells
20100 citationsauthor #10
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK2) Contributes to Secondary Damage after Spinal Cord Injury
201055 citationsauthor #6
Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples.
201064 citationsauthor #10
Ceramide in Cystic Fibrosis: A Potential New Target for Therapeutic Intervention
201026 citationsauthor #3
Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death.
2010119 citationsauthor #4
Immunity to protozoan parasite infection (PP-002)
20103 citationsauthor #18

TIMELINE

1981 1 citations

1982 0 citations

1985 0 citations

1987 206 citations

1988 203 citations

1989 85 citations

1990 74 citations

1991 117 citations

1992 5 citations

1993 315 citations

1994 122 citations

1995 272 citations

1996 24 citations

1997 472 citations

1998 204 citations

1999 30 citations

2000 96 citations

2001 263 citations

2002 61 citations

2003 208 citations

2004 69 citations

2005 491 citations

2006 354 citations

2007 528 citations

2008 216 citations

2009 333 citations

2010 877 citations

2011 190 citations

2012 132 citations

2013 212 citations

2014 209 citations

2015 424 citations

2016 951 citations

2017 48 citations

2018 25 citations

2019 46 citations

2020 57 citations

2021 69 citations

2022 32 citations

2023 5 citations

D. Radzioch

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